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VPGTAGIANLANVLTGLRFVLVPIFLYLLFYDGGHQTTFRIAAWAVFAVASITDRFDGLLARNYGMATEF GAFVDPIADKALIGAALIGLSMLNDLPWWVTVLILSRELGVTMLRLAVIRRGVIPASWGGKLKTVVQAVA IGLFVLPLSGPLHMAAVVVMAAAIVLTVVTGIDYVASTVREIRAGKRAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1969 | pgsA3 | - | 100% (189) | PGP synthase PgsA3 |
| M. marinum M | MMAR_2699 | pgsA2 | 4e-11 | 26.15% (130) | CDP-diacylglycerol--glycerol-3-phosphate 3- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2767c | pgsA3 | 1e-81 | 80.77% (182) | CDP-diacylglycerol--glycerol-3-phosphate |
| M. gilvum PYR-GCK | Mflv_3989 | - | 1e-63 | 66.48% (179) | CDP-diacylglycerol--glycerol-3-phosphate |
| M. tuberculosis H37Rv | Rv2746c | pgsA3 | 1e-81 | 80.77% (182) | CDP-diacylglycerol--glycerol-3-phosphate |
| M. leprae Br4923 | MLBr_00979 | - | 2e-74 | 76.67% (180) | CDP-diacylglycerol--glycerol-3-phosphate |
| M. abscessus ATCC 19977 | MAB_3071c | - | 8e-59 | 59.77% (174) | PGP synthase PgsA3 (phosphatidylglycerophosphate synthase) |
| M. avium 104 | MAV_3637 | pgsA | 1e-73 | 75.54% (184) | CDP-diacylglycerol--glycerol-3-phosphate |
| M. smegmatis MC2 155 | MSMEG_2692 | pgsA | 9e-66 | 68.68% (182) | CDP-diacylglycerol--glycerol-3-phosphate |
| M. thermoresistible (build 8) | TH_0577 | pgsA3 | 8e-65 | 68.33% (180) | PROBABLE PGP SYNTHASE PGSA3 |
| M. ulcerans Agy99 | MUL_3388 | pgsA3 | 1e-102 | 99.47% (189) | PGP synthase PgsA3 |
| M. vanbaalenii PYR-1 | Mvan_2395 | - | 8e-66 | 69.27% (179) | CDP-diacylglycerol--glycerol-3-phosphate |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3989|M.gilvum_PYR-GCK ----------------MCNQYSVAVPGQPHTDPVVPRARVANIANVLTGI
Mvan_2395|M.vanbaalenii_PYR-1 ----------------------MAVPGQPHTDPVVPRARVANLANLLTGI
MSMEG_2692|M.smegmatis_MC2_155 ------------------------MPGQPSTDPVVPRARVANLANVLTGI
TH_0577|M.thermoresistible__bu ---------------------------------------VANLANALTGV
MMAR_1969|M.marinum_M ---------------------------------MPGTAGIANLANVLTGL
MUL_3388|M.ulcerans_Agy99 MTFGHEKTVSTSAAGRLVNRYSVAVSGQPQTGQVPGTVGIANLANVLTGL
Mb2767c|M.bovis_AF2122/97 --------MSRS------TRYSVAVSAQPETGQIAGRARIANLANILTLL
Rv2746c|M.tuberculosis_H37Rv --------MSRS------TRYSVAVSAQPETGQIAGRARIANLANILTLL
MLBr_00979|M.leprae_Br4923 ---------------------------------MVDCVRIANLANILTGL
MAV_3637|M.avium_104 ---------------------------------MVGRANIANLANTLTLL
MAB_3071c|M.abscessus_ATCC_199 --------------------MPMPPETQPDSAASAAPVPVLNIANILTVL
: *:** ** :
Mflv_3989|M.gilvum_PYR-GCK RMALVPVFLVALFVGDGHETFWRLTAFTIFLVAVITDRLDGALARSYGMV
Mvan_2395|M.vanbaalenii_PYR-1 RMALVPVFLFALFAGDGQETSWRITAFVVFAVAVITDRFDGALARSYGMV
MSMEG_2692|M.smegmatis_MC2_155 RMALVPVFLVFLFTDGGHEFFWRMAAFTVFAVAVITDRFDGALARSYGMV
TH_0577|M.thermoresistible__bu RLLLVPVFLILLFVGDGHETSWRIGAFAVFAVAVITDRFDGALARSYGMV
MMAR_1969|M.marinum_M RFVLVPIFLYLLFYDGGHQTTFRIAAWAVFAVASITDRFDGLLARNYGMA
MUL_3388|M.ulcerans_Agy99 RFVLVPIFLYLLFYDGGHQTTFRIAAWAVFAVASITDRFDGLLARNYGMA
Mb2767c|M.bovis_AF2122/97 RLVMVPVFLLALFYGGGHHSAARVVAWAIFATACITDRFDGLLARNYGMA
Rv2746c|M.tuberculosis_H37Rv RLVMVPVFLLALFYGGGHHSAARVVAWAIFATACITDRFDGLLARNYGMA
MLBr_00979|M.leprae_Br4923 RLMLVPVFLVALFAGNGHEIVGRIAAFVIFTVACITDRLDGLLARRYGMA
MAV_3637|M.avium_104 RLVLVPVFLLALFAGDGHETGFRILAFLIFAFACITDRLDGLLARNYGMA
MAB_3071c|M.abscessus_ATCC_199 RIVLVPVFVVVLFTEGGHQSSWRIAAFGVFALAIATDRYDGILARRYGLI
*: :**:*: ** .*:. *: *: :* * *** ** *** **:
Mflv_3989|M.gilvum_PYR-GCK TEFGTLADPIADKMLIGSALVGLSILGDLPWWVTVVILVREVAVTVLRLV
Mvan_2395|M.vanbaalenii_PYR-1 TEFGTLADPIADKALIGSALVGLSVLGDLPWWVTVVILVRELGVTLLRLV
MSMEG_2692|M.smegmatis_MC2_155 TEFGALADPIADKALIGAALIGLSMLGDLPWWVTAVVLAREIGITLMRLA
TH_0577|M.thermoresistible__bu TEFGTLADPIADKALIGAALIGLSLLGDLPWWVTAVILVREIGITALRFA
MMAR_1969|M.marinum_M TEFGAFVDPIADKALIGAALIGLSMLNDLPWWVTVLILSRELGVTMLRLA
MUL_3388|M.ulcerans_Agy99 TEFGAFVDPIADKALIGAALIGLSMLNDLPWWVTVLILSRELGVTMLRLA
Mb2767c|M.bovis_AF2122/97 TEFGAFVDPIADKTLIGSALIGLSMLGDLPWWVTVLILTRELGVTVLRLA
Rv2746c|M.tuberculosis_H37Rv TEFGAFVDPIADKTLIGSALIGLSMLGDLPWWVTVLILTRELGVTVLRLA
MLBr_00979|M.leprae_Br4923 TEFGAFVDPIADKTLIGAALIGLSMLGDLPWWVTVLIMTRELGVTLLRLA
MAV_3637|M.avium_104 TEFGAFVDPIADKTLVGSALIGLSMLGELPWWITVLILAREFGVTVLRLA
MAB_3071c|M.abscessus_ATCC_199 TPFGQLADPIADKALICAALVGLSLLGDLSWWVTAVILVREIGITVLRFS
* ** :.****** *: :**:***:*.:*.**:*.::: **..:* :*:
Mflv_3989|M.gilvum_PYR-GCK VLRRGVIPASRGGKIKTLVQAVAIGLFVMPLS---GAWLTGAWVIMAAAG
Mvan_2395|M.vanbaalenii_PYR-1 VLRRGVIPASRGGKLKTLVQAVAIGLFVLPLS---DGWLTGAWVIMLAAV
MSMEG_2692|M.smegmatis_MC2_155 VLRHGVIPASRGGKLKTTVQAVAIGLFVMPLYAWSPVWTTVAWAIMWAAV
TH_0577|M.thermoresistible__bu VLRHGVIPASRGGKLKTLAQAVAIGLFVLPLANWAPVWSTVAWGIMAVAV
MMAR_1969|M.marinum_M VIRRGVIPASWGGKLKTVVQAVAIGLFVLPLSG---PLHMAAVVVMAAAI
MUL_3388|M.ulcerans_Agy99 VIRRGVIPASWGGKLKTVVQAVAIGLFVLPLSG---PLHMAAVVVMAAAI
Mb2767c|M.bovis_AF2122/97 VIRRGVIPASWGGKLKTFVQAVAIGLFVLPLSG---PLHVAAVVVMAAAI
Rv2746c|M.tuberculosis_H37Rv VIRRGVIPASWGGKLKTFVQAVAIGLFVLPLSG---PLHVAAVVVMAAAI
MLBr_00979|M.leprae_Br4923 VIHRGVIPASWGGKLKTVVQAVAIGLFLLPLTQLSVPFHVGAAVVMAVAV
MAV_3637|M.avium_104 VIRRGVIPASWGGKLKTVVQVFAIGLFVLPWAGTPGPFRVGAAVVMGAAI
MAB_3071c|M.abscessus_ATCC_199 VLRHGVIPANRGGKLKTLVQSLAIAGYLLPLTG---HWHTAALILMGLAV
*:::*****. ***:** .* .**. :::* * :* *
Mflv_3989|M.gilvum_PYR-GCK VLTVLTGVDYFVSAVRDWRRQSPGR-
Mvan_2395|M.vanbaalenii_PYR-1 ALTVTTGVDYFVSAVRDWRGRSAGQ-
MSMEG_2692|M.smegmatis_MC2_155 VLTVLTGADYVVSAIRDSRGRPADN-
TH_0577|M.thermoresistible__bu VLTVFTGVDYVVSAVRDSRGRSAGH-
MMAR_1969|M.marinum_M VLTVVTGIDYVASTVREIRAGKRAS-
MUL_3388|M.ulcerans_Agy99 VLTVVTGIDYVASTVREIRAGKRAS-
Mb2767c|M.bovis_AF2122/97 LLTVITGVDYVARALRDIGGIRQTAS
Rv2746c|M.tuberculosis_H37Rv LLTVITGVDYVARALRDIGGIRQTAS
MLBr_00979|M.leprae_Br4923 VLTVVTGVDYVAGTIRAVRGVHQTAS
MAV_3637|M.avium_104 VLTVITGIDYVVSTVREVR---RTAA
MAB_3071c|M.abscessus_ATCC_199 ALTVITGIDYLVQALRPRPKTP----
*** ** **.. ::*