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M. thermoresistible (build 8) TH_0577 (pgsA3)

annotation: PROBABLE PGP SYNTHASE PGSA3 (CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE) (PHOSPHATIDYLGLYCEROPHOSPHATE SYNTHASE)
coordinates: 1229050 - 1229610
length: 187

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0577 pgsA3 - 100% (187) PROBABLE PGP SYNTHASE PGSA3 (CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE) (PHOSPHATIDYLGLYCEROPHOSPHATE SYNTHASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2767c pgsA3 1e-62 65.75% (181) CDP-diacylglycerol--glycerol-3-phosphate
M. gilvum PYR-GCK Mflv_3989 - 3e-75 75.14% (185) CDP-diacylglycerol--glycerol-3-phosphate
M. tuberculosis H37Rv Rv2746c pgsA3 1e-62 65.75% (181) CDP-diacylglycerol--glycerol-3-phosphate
M. leprae Br4923 MLBr_00979 - 6e-65 66.85% (181) CDP-diacylglycerol--glycerol-3-phosphate
M. abscessus ATCC 19977 MAB_3071c - 1e-63 66.67% (177) PGP synthase PgsA3 (phosphatidylglycerophosphate synthase)
M. marinum M MMAR_1969 pgsA3 1e-64 68.33% (180) PGP synthase PgsA3
M. avium 104 MAV_3637 pgsA 4e-63 64.13% (184) CDP-diacylglycerol--glycerol-3-phosphate
M. smegmatis MC2 155 MSMEG_2692 pgsA 8e-83 80.98% (184) CDP-diacylglycerol--glycerol-3-phosphate
M. ulcerans Agy99 MUL_3388 pgsA3 8e-65 68.33% (180) PGP synthase PgsA3
M. vanbaalenii PYR-1 Mvan_2395 - 1e-78 80.54% (185) CDP-diacylglycerol--glycerol-3-phosphate

CLUSTAL 2.0.9 multiple sequence alignment


TH_0577|M.thermoresistible__bu      ---------------------------------------VANLANALTGV
MSMEG_2692|M.smegmatis_MC2_155      ------------------------MPGQPSTDPVVPRARVANLANVLTGI
Mflv_3989|M.gilvum_PYR-GCK          ----------------MCNQYSVAVPGQPHTDPVVPRARVANIANVLTGI
Mvan_2395|M.vanbaalenii_PYR-1       ----------------------MAVPGQPHTDPVVPRARVANLANLLTGI
MLBr_00979|M.leprae_Br4923          ---------------------------------MVDCVRIANLANILTGL
MAV_3637|M.avium_104                ---------------------------------MVGRANIANLANTLTLL
Mb2767c|M.bovis_AF2122/97           --------MSRS------TRYSVAVSAQPETGQIAGRARIANLANILTLL
Rv2746c|M.tuberculosis_H37Rv        --------MSRS------TRYSVAVSAQPETGQIAGRARIANLANILTLL
MMAR_1969|M.marinum_M               ---------------------------------MPGTAGIANLANVLTGL
MUL_3388|M.ulcerans_Agy99           MTFGHEKTVSTSAAGRLVNRYSVAVSGQPQTGQVPGTVGIANLANVLTGL
MAB_3071c|M.abscessus_ATCC_199      --------------------MPMPPETQPDSAASAAPVPVLNIANILTVL
                                                                           : *:** ** :

TH_0577|M.thermoresistible__bu      RLLLVPVFLILLFVGDGHETSWRIGAFAVFAVAVITDRFDGALARSYGMV
MSMEG_2692|M.smegmatis_MC2_155      RMALVPVFLVFLFTDGGHEFFWRMAAFTVFAVAVITDRFDGALARSYGMV
Mflv_3989|M.gilvum_PYR-GCK          RMALVPVFLVALFVGDGHETFWRLTAFTIFLVAVITDRLDGALARSYGMV
Mvan_2395|M.vanbaalenii_PYR-1       RMALVPVFLFALFAGDGQETSWRITAFVVFAVAVITDRFDGALARSYGMV
MLBr_00979|M.leprae_Br4923          RLMLVPVFLVALFAGNGHEIVGRIAAFVIFTVACITDRLDGLLARRYGMA
MAV_3637|M.avium_104                RLVLVPVFLLALFAGDGHETGFRILAFLIFAFACITDRLDGLLARNYGMA
Mb2767c|M.bovis_AF2122/97           RLVMVPVFLLALFYGGGHHSAARVVAWAIFATACITDRFDGLLARNYGMA
Rv2746c|M.tuberculosis_H37Rv        RLVMVPVFLLALFYGGGHHSAARVVAWAIFATACITDRFDGLLARNYGMA
MMAR_1969|M.marinum_M               RFVLVPIFLYLLFYDGGHQTTFRIAAWAVFAVASITDRFDGLLARNYGMA
MUL_3388|M.ulcerans_Agy99           RFVLVPIFLYLLFYDGGHQTTFRIAAWAVFAVASITDRFDGLLARNYGMA
MAB_3071c|M.abscessus_ATCC_199      RIVLVPVFVVVLFTEGGHQSSWRIAAFGVFALAIATDRYDGILARRYGLI
                                    *: :**:*:  **  .*:.   *: *: :*  *  *** ** *** **: 

TH_0577|M.thermoresistible__bu      TEFGTLADPIADKALIGAALIGLSLLGDLPWWVTAVILVREIGITALRFA
MSMEG_2692|M.smegmatis_MC2_155      TEFGALADPIADKALIGAALIGLSMLGDLPWWVTAVVLAREIGITLMRLA
Mflv_3989|M.gilvum_PYR-GCK          TEFGTLADPIADKMLIGSALVGLSILGDLPWWVTVVILVREVAVTVLRLV
Mvan_2395|M.vanbaalenii_PYR-1       TEFGTLADPIADKALIGSALVGLSVLGDLPWWVTVVILVRELGVTLLRLV
MLBr_00979|M.leprae_Br4923          TEFGAFVDPIADKTLIGAALIGLSMLGDLPWWVTVLIMTRELGVTLLRLA
MAV_3637|M.avium_104                TEFGAFVDPIADKTLVGSALIGLSMLGELPWWITVLILAREFGVTVLRLA
Mb2767c|M.bovis_AF2122/97           TEFGAFVDPIADKTLIGSALIGLSMLGDLPWWVTVLILTRELGVTVLRLA
Rv2746c|M.tuberculosis_H37Rv        TEFGAFVDPIADKTLIGSALIGLSMLGDLPWWVTVLILTRELGVTVLRLA
MMAR_1969|M.marinum_M               TEFGAFVDPIADKALIGAALIGLSMLNDLPWWVTVLILSRELGVTMLRLA
MUL_3388|M.ulcerans_Agy99           TEFGAFVDPIADKALIGAALIGLSMLNDLPWWVTVLILSRELGVTMLRLA
MAB_3071c|M.abscessus_ATCC_199      TPFGQLADPIADKALICAALVGLSLLGDLSWWVTAVILVREIGITVLRFS
                                    * ** :.****** *: :**:***:*.:*.**:*.::: **..:* :*: 

TH_0577|M.thermoresistible__bu      VLRHGVIPASRGGKLKTLAQAVAIGLFVLPLANWAPVWSTVAWGIMAVAV
MSMEG_2692|M.smegmatis_MC2_155      VLRHGVIPASRGGKLKTTVQAVAIGLFVMPLYAWSPVWTTVAWAIMWAAV
Mflv_3989|M.gilvum_PYR-GCK          VLRRGVIPASRGGKIKTLVQAVAIGLFVMPLS---GAWLTGAWVIMAAAG
Mvan_2395|M.vanbaalenii_PYR-1       VLRRGVIPASRGGKLKTLVQAVAIGLFVLPLS---DGWLTGAWVIMLAAV
MLBr_00979|M.leprae_Br4923          VIHRGVIPASWGGKLKTVVQAVAIGLFLLPLTQLSVPFHVGAAVVMAVAV
MAV_3637|M.avium_104                VIRRGVIPASWGGKLKTVVQVFAIGLFVLPWAGTPGPFRVGAAVVMGAAI
Mb2767c|M.bovis_AF2122/97           VIRRGVIPASWGGKLKTFVQAVAIGLFVLPLSG---PLHVAAVVVMAAAI
Rv2746c|M.tuberculosis_H37Rv        VIRRGVIPASWGGKLKTFVQAVAIGLFVLPLSG---PLHVAAVVVMAAAI
MMAR_1969|M.marinum_M               VIRRGVIPASWGGKLKTVVQAVAIGLFVLPLSG---PLHMAAVVVMAAAI
MUL_3388|M.ulcerans_Agy99           VIRRGVIPASWGGKLKTVVQAVAIGLFVLPLSG---PLHMAAVVVMAAAI
MAB_3071c|M.abscessus_ATCC_199      VLRHGVIPANRGGKLKTLVQSLAIAGYLLPLTG---HWHTAALILMGLAV
                                    *:::*****. ***:** .* .**. :::*           *  :*  * 

TH_0577|M.thermoresistible__bu      VLTVFTGVDYVVSAVRDSRGRSAGH-
MSMEG_2692|M.smegmatis_MC2_155      VLTVLTGADYVVSAIRDSRGRPADN-
Mflv_3989|M.gilvum_PYR-GCK          VLTVLTGVDYFVSAVRDWRRQSPGR-
Mvan_2395|M.vanbaalenii_PYR-1       ALTVTTGVDYFVSAVRDWRGRSAGQ-
MLBr_00979|M.leprae_Br4923          VLTVVTGVDYVAGTIRAVRGVHQTAS
MAV_3637|M.avium_104                VLTVITGIDYVVSTVREVR---RTAA
Mb2767c|M.bovis_AF2122/97           LLTVITGVDYVARALRDIGGIRQTAS
Rv2746c|M.tuberculosis_H37Rv        LLTVITGVDYVARALRDIGGIRQTAS
MMAR_1969|M.marinum_M               VLTVVTGIDYVASTVREIRAGKRAS-
MUL_3388|M.ulcerans_Agy99           VLTVVTGIDYVASTVREIRAGKRAS-
MAB_3071c|M.abscessus_ATCC_199      ALTVITGIDYLVQALRPRPKTP----
                                     *** ** **.. ::*

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0577	pgsA3	-	100% (187)	PROBABLE PGP SYNTHASE PGSA3 (CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE) (PHOSPHATIDYLGLYCEROPHOSPHATE SYNTHASE)