For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRQFSDRIDAGRKLGRRLEFLRGQDIVVLGLPRGGVPVAFEVAKALHAPLDVLLVRKLGVPLHSELAFGA IGEGGVQVINSAVVHEAGLGEQEMAAVETAQWAELQRRVQRYRGDRHPIPLRGRIAVIVDDGVATGATAA AACQVARAQGASRVILAVPIGATDTAPRFTEYADEVVCLETPTPYFAVGQGYDNFTQTSDQEVVTLLDRA RSEFGAGHQPPVPARRDDGVRVLAGPASVIGRLTIPDRPTGIVVFAHGSGSSRHSPRNRYVAEVLNQAGL ATLLLDLLTPEEEHNRANVFDIGLLARRLVDVTGWLAAQPDTTALPVGFFGASTGGGAALVAAAHPGVKV QAVVSRGGRPDLAGDALREVHAPTLPIVGGRDEAVLELNRQAQAAIPAPCELVVVPGATHLFEEPGALEQ VATLARDWFLGHLRHH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3276 | - | - | 100% (436) | hypothetical protein MUL_3276 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0586c | - | 1e-167 | 70.41% (436) | hypothetical protein Mb0586c |
| M. gilvum PYR-GCK | Mflv_2998 | - | 2e-45 | 47.91% (215) | phosphoribosyltransferase |
| M. tuberculosis H37Rv | Rv0571c | - | 1e-167 | 70.41% (436) | hypothetical protein Rv0571c |
| M. leprae Br4923 | MLBr_00248 | prsA | 3e-05 | 36.36% (66) | ribose-phosphate pyrophosphokinase |
| M. abscessus ATCC 19977 | MAB_4659 | - | 3e-38 | 42.72% (206) | hypothetical protein MAB_4659 |
| M. marinum M | MMAR_2069 | - | 0.0 | 99.08% (436) | hypothetical protein MMAR_2069 |
| M. avium 104 | MAV_2347 | - | 1e-46 | 49.06% (212) | phosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_4215 | - | 2e-48 | 49.04% (208) | phosphoribosyltransferase |
| M. thermoresistible (build 8) | TH_3117 | - | 1e-167 | 70.09% (438) | PUTATIVE Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) |
| M. vanbaalenii PYR-1 | Mvan_1399 | - | 2e-75 | 71.08% (204) | hypothetical protein Mvan_1399 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3276|M.ulcerans_Agy99 ------------MRQFSDRI--DAGRKLGRRLEFLRGQD---------IV
MMAR_2069|M.marinum_M ------------MRQFSDRI--DAGRKLGRRLEFLRGQD---------IV
Mb0586c|M.bovis_AF2122/97 ------------MKLFDDRG--DAGRQLAQRLAQLSGKA---------VV
Rv0571c|M.tuberculosis_H37Rv ------------MKLFDDRG--DAGRQLAQRLAQLSGKA---------VV
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3117|M.thermoresistible__bu --------MRADTRPFDDRV--DAGRRPAERLASFRGRD---------VV
MAV_2347|M.avium_104 ------------MRSFRDRR--EAGRALAGELMGYRNRGD--------VL
MSMEG_4215|M.smegmatis_MC2_155 --MSAWSVRHDAIRTFQDRR--EAGRVLAQRLSSYRDDPD--------VL
Mflv_2998|M.gilvum_PYR-GCK --------MKASARTFHDRR--DAGRVLARDLCDRISRPDAGDGDLGEIL
MAB_4659|M.abscessus_ATCC_1997 --------MSDTHRMFSDRQ--DAGRVLAGMLAPRKLRS---------IV
MLBr_00248|M.leprae_Br4923 MLSHDWTDNRKNLMLFSGRAHPELAEQVAKELDMHVTTQDAREFANG-EI
MUL_3276|M.ulcerans_Agy99 VLGLPRGGVPVAFEVAKALHAPLDVLLVRKLGVPLHSELAFGAIGEGGVQ
MMAR_2069|M.marinum_M VLGLPRGGVPVAFEVAKALHAPLDVLLVRKLGVPLHSELAFGAIGEGGVQ
Mb0586c|M.bovis_AF2122/97 VLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVR
Rv0571c|M.tuberculosis_H37Rv VLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVR
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3117|M.thermoresistible__bu VLGLPRGGVPVAFAVARALRAPLDVLVVRKLGVPFQPELAFGAIGEDGVR
MAV_2347|M.avium_104 VFGLARGGLPVAWEIAAALHAPLDVFLVRKLG------------------
MSMEG_4215|M.smegmatis_MC2_155 VLGLARGGVPVAWEVAAHLRAPLDVFLVRKLG------------------
Mflv_2998|M.gilvum_PYR-GCK VLGLARGGVPVGWEVAQRLKAPLDVCLVRKLG------------------
MAB_4659|M.abscessus_ATCC_1997 VLALPRGGIPVGREIATALNAPLAVLVVRKLG------------------
MLBr_00248|M.leprae_Br4923 FVRFHESVRGCDAFVLQSCPAPVNTWLMEQLIMIDALKRGSAKRITAVIP
MUL_3276|M.ulcerans_Agy99 VINSAVVHEAGLGEQEMAAVETAQWAELQRRVQRYRGDRHPIPLRGRIAV
MMAR_2069|M.marinum_M VINSAVVHEAGLGEQEMAAVETAQWAELQRRVQRYRGDRHPIPLRGRIAV
Mb0586c|M.bovis_AF2122/97 VLNDDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAV
Rv0571c|M.tuberculosis_H37Rv VLNDDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAV
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3117|M.thermoresistible__bu VVNDAVVRRTRLTRADMAAVERRERAELQRRSERYRGGRSRIPLSGRVAV
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2998|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00248|M.leprae_Br4923 FYPYARQDKKHRGREPISARLVADLLKTAGADRIVTVDLHTDQIQGFFDG
MUL_3276|M.ulcerans_Agy99 IVDDGVATGATAAAACQVARAQGASRVILAVPIGATDTAPRFTEYADEVV
MMAR_2069|M.marinum_M IVDDGVATGATAAAACQVARAQGASRVILAVPIGATDTAPRFTEYADEVV
Mb0586c|M.bovis_AF2122/97 IVDDGIATGATAKAACQVARAHGADKVVLAVPIGPDDIVARFAGYADEVV
Rv0571c|M.tuberculosis_H37Rv IVDDGIATGATAKAACQVARAHGADKVVLAVPIGPDDIVARFAGYADEVV
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3117|M.thermoresistible__bu IVDDGVATGATAKAACQVVRAEGAARVVLAVPVGPPDVAERFAGYADEVV
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2998|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00248|M.leprae_Br4923 --------------------------------------------------
MUL_3276|M.ulcerans_Agy99 CLETPTPYFAVGQGYDNFTQTSDQEVVTLLDRARSEFGAG---HQPPVPA
MMAR_2069|M.marinum_M CLETPTPYFAVGQGYDNFTQTSDQEVVTLLDRARSEFGAG---HQPPVPA
Mb0586c|M.bovis_AF2122/97 CLATPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPP
Rv0571c|M.tuberculosis_H37Rv CLATPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPP
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3117|M.thermoresistible__bu CLQTPPFFSAVGQGYRNFTQTSDDEVIALLRRARADVADTAAADIGDPPP
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2998|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00248|M.leprae_Br4923 --------------------------------------------------
MUL_3276|M.ulcerans_Agy99 RRDDGVRVLAGPASVIGRLTIPDRPT---GIVVFAHGSGSSRHSPRNRYV
MMAR_2069|M.marinum_M RRDDEVRVLAGPVSVIGRLTIPDRPT---GIVVFAHGSGSSRHSPRNRYV
Mb0586c|M.bovis_AF2122/97 LRDEEVQVVAGPVPVAGHLTVPEKPR---GIVVFAHGSGSSRHSIRNRYV
Rv0571c|M.tuberculosis_H37Rv LRDEEVQVVAGPVPVAGHLTVPEKPR---GIVVFAHGSGSSRHSIRNRYV
Mvan_1399|M.vanbaalenii_PYR-1 -----MRVSTAAADLDGYLTVPENAR---GVVVFAHGSGSSRHSIRNRYV
TH_3117|M.thermoresistible__bu LRDEEVRVDAGGVTVTGHLTVPGQPI---GVVVFAHGSG--RHSPRNRYV
MAV_2347|M.avium_104 ------------VPNWSELAMGALAS---GGGVVMNDDVVSSLRITDEQV
MSMEG_4215|M.smegmatis_MC2_155 ------------VPQWQELAMGAVAS---GGGVVLNEKLMDRLGISDDDM
Mflv_2998|M.gilvum_PYR-GCK ------------APQWPELAIGALAG---GGGVVLNNELIRSLGVGEDQI
MAB_4659|M.abscessus_ATCC_1997 ------------VPGHEEYAMGAIAS---GGEVILDDDIVRSMGVTPIQL
MLBr_00248|M.leprae_Br4923 ---------PVDHMRGQNLLTGYIKNNYPDTNMVVVSPDSGRVRIAEK-W
. :.
MUL_3276|M.ulcerans_Agy99 AEVLNQAGLATLLLDLLTPEEEHNRANVFDIGLLARRLVDVTGWLAAQPD
MMAR_2069|M.marinum_M AEVLNQAGLATLLLDLLTPEEEHNRANVFDIGLLARRLVDVTGWLAAQPD
Mb0586c|M.bovis_AF2122/97 AEVLTGAGFATLLFDLLTPEEERNRANVFDIELLASRLIDVTGWLATQPD
Rv0571c|M.tuberculosis_H37Rv AEVLTGAGFATLLFDLLTPEEERNRANVFDIELLASRLIDVTGWLATQPD
Mvan_1399|M.vanbaalenii_PYR-1 AKVLNEAGLATLLFDLLTPAEEADRANVFDIDLLAGRLVDVTLWLAGRPD
TH_3117|M.thermoresistible__bu ADVLRRAGLATLLFDLLTPDEELDRANVFDIGLLAERLVGVTQWLAAQPE
MAV_2347|M.avium_104 RAVIDSETAE------LARREHAYRGDRPMADLRDKVVILVDDGIATGAS
MSMEG_4215|M.smegmatis_MC2_155 AETLRRETIE------LERREQAYRGDREPLQVAGRTVILVDDGIATGAS
Mflv_2998|M.gilvum_PYR-GCK RDIVCRETAE------LHRREKAYRGDRGPVTVSGRTVVLVDDGIATGAS
MAB_4659|M.abscessus_ATCC_1997 DEVTDRERRE------LARRERIYLAHRS-VEIRDKTVILVDDGIATGAT
MLBr_00248|M.leprae_Br4923 GDALGGVPLAFIHKTRDLRVPNQVVSNRVVGEVEGRTCVLIDDMIDTGGT
. .. : : : :
MUL_3276|M.ulcerans_Agy99 TTALPVGFFGASTGGGAALVAAAHPGVKVQAVVSRGGRPDLAGDALREVH
MMAR_2069|M.marinum_M TTALPVGFFGASTGAGAALVAAAHPGVKVQAVVSRGGRPDLAGDALREVH
Mb0586c|M.bovis_AF2122/97 TASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDLAGDSLGSVV
Rv0571c|M.tuberculosis_H37Rv TASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDLAGDSLGSVV
Mvan_1399|M.vanbaalenii_PYR-1 LAVLPVGYFGASTGAGAALTAAADRRVDIAAVVSRGGRPDLAGVHLGAVT
TH_3117|M.thermoresistible__bu TAALPVGYFGASTGAGAALVAAADPRVQVAAVVSRGGRPDLAGQALGKVR
MAV_2347|M.avium_104 MLAAVRALRSGPTGATPRSIVVAVP-VGPESACRELGR--EADEVVCLST
MSMEG_4215|M.smegmatis_MC2_155 MMAAVRAVRG------ARRVVVAVP-VGPPGVCRELAA--EADDVVCASM
Mflv_2998|M.gilvum_PYR-GCK MIAAVRSVREAG----ARRIIVGVP-VGPRAACRLLRS--EADLVVCSTT
MAB_4659|M.abscessus_ATCC_1997 MRVALLTVKRAS----PARVVAAVP-VAPRSAVGRFGS--LVDDFVVATC
MLBr_00248|M.leprae_Br4923 VAGAVQLLRNDG---ASDVIIAATHGVLSPPAAERLAQYGTREVIVTNTL
. .. * . :
MUL_3276|M.ulcerans_Agy99 APTLPIVGGRDEAVLELNRQAQAAIPAPCELVVVPGATHLFEEPGALEQV
MMAR_2069|M.marinum_M APTLLIVGGRDEAVLELNRQAQAAIPAPCELVVVPGATHLFEEPGALEQV
Mb0586c|M.bovis_AF2122/97 APTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLFEEPGTLEQV
Rv0571c|M.tuberculosis_H37Rv APTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLFEEPGTLEQV
Mvan_1399|M.vanbaalenii_PYR-1 APTLLIVGSRDEVVLELNQRAQAAMSAECTIAVVPGATHLFEEPGTLEQA
TH_3117|M.thermoresistible__bu APTLLIVGGRDRFVLELNHQARAAIPAVCEIAVIPGATHLFEEPGALDQV
MAV_2347|M.avium_104 PPGFEAVG---QVYGDFHQVSDDEVRELLATPTG----------------
MSMEG_4215|M.smegmatis_MC2_155 PQDFEAVG---QAFADFHQVSDDEVRELLATPTTDPVR------------
Mflv_2998|M.gilvum_PYR-GCK PPNFRAVG---QVYADFHQVSDEEVRELLAAG------------------
MAB_4659|M.abscessus_ATCC_1997 PSRFQAVG---DAYRDFHQISDREVRELLSAPVIR---------------
MLBr_00248|M.leprae_Br4923 PIGEEKRFP-QLTVLSIAPLLASTIRAIFENGSVTGLFDGEA--------
. .: :
MUL_3276|M.ulcerans_Agy99 ATLARDWFLGHLRHH------
MMAR_2069|M.marinum_M ATLARDWFLGHLRHH------
Mb0586c|M.bovis_AF2122/97 AKLACDWFIDHLCGPGPSG--
Rv0571c|M.tuberculosis_H37Rv AKLACDWFIDHLCGPGPSG--
Mvan_1399|M.vanbaalenii_PYR-1 AALARDWFVRHLGTPG--G--
TH_3117|M.thermoresistible__bu AELARDWFTDHLSRTGASTRP
MAV_2347|M.avium_104 ---------------------
MSMEG_4215|M.smegmatis_MC2_155 ---------------------
Mflv_2998|M.gilvum_PYR-GCK ---------------------
MAB_4659|M.abscessus_ATCC_1997 ---------------------
MLBr_00248|M.leprae_Br4923 ---------------------