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KLFDDRGDAGRQLAQRLAQLSGKAVVVLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAI GEDGVRVLNDDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAVIVDDGIATGATAKA ACQVARAHGADKVVLAVPIGPDDIVARFAGYADEVVCLATPALFFAVGQGYRNFTQTSDDEVVAFLDRAH RDFAEAGAIDAAADPPLRDEEVQVVAGPVPVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGA GFATLLFDLLTPEEERNRANVFDIELLASRLIDVTGWLATQPDTASLPVGYFGASTGAGAALVAAADPRV NVRAVVSRGGRPDLAGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLFEEPGTL EQVAKLACDWFIDHLCGPGPSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0571c | - | - | 100% (443) | hypothetical protein Rv0571c |
| M. tuberculosis H37Rv | Rv2143 | - | 8e-45 | 49.75% (201) | hypothetical protein Rv2143 |
| M. tuberculosis H37Rv | Rv2030c | - | 2e-42 | 44.83% (203) | hypothetical protein Rv2030c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0586c | - | 0.0 | 100.00% (443) | hypothetical protein Mb0586c |
| M. gilvum PYR-GCK | Mflv_4988 | - | 4e-42 | 43.32% (217) | erythromycin esterase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4659 | - | 1e-40 | 45.05% (202) | hypothetical protein MAB_4659 |
| M. marinum M | MMAR_2069 | - | 1e-169 | 71.33% (436) | hypothetical protein MMAR_2069 |
| M. avium 104 | MAV_2347 | - | 2e-41 | 47.12% (208) | phosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_4215 | - | 1e-44 | 48.53% (204) | phosphoribosyltransferase |
| M. thermoresistible (build 8) | TH_3117 | - | 0.0 | 74.26% (439) | PUTATIVE Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) |
| M. ulcerans Agy99 | MUL_3276 | - | 1e-167 | 70.41% (436) | hypothetical protein MUL_3276 |
| M. vanbaalenii PYR-1 | Mvan_1399 | - | 1e-82 | 74.04% (208) | hypothetical protein Mvan_1399 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0571c|M.tuberculosis_H37Rv ------------MKLFDDRGDAGRQLAQRLAQLSGK-AVVVLGLPRGGVP
Mb0586c|M.bovis_AF2122/97 ------------MKLFDDRGDAGRQLAQRLAQLSGK-AVVVLGLPRGGVP
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2069|M.marinum_M ------------MRQFSDRIDAGRKLGRRLEFLRGQ-DIVVLGLPRGGVP
MUL_3276|M.ulcerans_Agy99 ------------MRQFSDRIDAGRKLGRRLEFLRGQ-DIVVLGLPRGGVP
TH_3117|M.thermoresistible__bu --------MRADTRPFDDRVDAGRRPAERLASFRGR-DVVVLGLPRGGVP
Mflv_4988|M.gilvum_PYR-GCK MTTARRAASDQPRRVFRDRREAGQALAGLLGGYRGRENVVVLGLARGGIP
MAV_2347|M.avium_104 ------------MRSFRDRREAGRALAGELMGYRNRGDVLVFGLARGGLP
MSMEG_4215|M.smegmatis_MC2_155 --MSAWSVRHDAIRTFQDRREAGRVLAQRLSSYRDDPDVLVLGLARGGVP
MAB_4659|M.abscessus_ATCC_1997 --------MSDTHRMFSDRQDAGRVLAGMLAPRKLR-SIVVLALPRGGIP
Rv0571c|M.tuberculosis_H37Rv VAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVLNDDVVRGT
Mb0586c|M.bovis_AF2122/97 VAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVLNDDVVRGT
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2069|M.marinum_M VAFEVAKALHAPLDVLLVRKLGVPLHSELAFGAIGEGGVQVINSAVVHEA
MUL_3276|M.ulcerans_Agy99 VAFEVAKALHAPLDVLLVRKLGVPLHSELAFGAIGEGGVQVINSAVVHEA
TH_3117|M.thermoresistible__bu VAFAVARALRAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVVNDAVVRRT
Mflv_4988|M.gilvum_PYR-GCK VAWEVAAALGAPLDAFIVRKLGAPGHDEFAMGALASGGRVVVNDDVVRAL
MAV_2347|M.avium_104 VAWEIAAALHAPLDVFLVRKLGVPNWSELAMGALASGGGVVMNDDVVSSL
MSMEG_4215|M.smegmatis_MC2_155 VAWEVAAHLRAPLDVFLVRKLGVPQWQELAMGAVASGGGVVLNEKLMDRL
MAB_4659|M.abscessus_ATCC_1997 VGREIATALNAPLAVLVVRKLGVPGHEEYAMGAIASGGEVILDDDIVRSM
Rv0571c|M.tuberculosis_H37Rv HLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAVIVDDGIATGA
Mb0586c|M.bovis_AF2122/97 HLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAVIVDDGIATGA
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2069|M.marinum_M GLGEQEMAAVETAQWAELQRRVQRYRGDRHPIPLRGRIAVIVDDGVATGA
MUL_3276|M.ulcerans_Agy99 GLGEQEMAAVETAQWAELQRRVQRYRGDRHPIPLRGRIAVIVDDGVATGA
TH_3117|M.thermoresistible__bu RLTRADMAAVERRERAELQRRSERYRGGRSRIPLSGRVAVIVDDGVATGA
Mflv_4988|M.gilvum_PYR-GCK RVSPQQPRDVAEREGRELLRREAAYRAGRPPLELAGKTVIVVDDGLATGS
MAV_2347|M.avium_104 RITDEQVRAVIDSETAELARREHAYRGDRPMADLRDKVVILVDDGIATGA
MSMEG_4215|M.smegmatis_MC2_155 GISDDDMAETLRRETIELERREQAYRGDREPLQVAGRTVILVDDGIATGA
MAB_4659|M.abscessus_ATCC_1997 GVTPIQLDEVTDRERRELARRERIYLAHR-SVEIRDKTVILVDDGIATGA
Rv0571c|M.tuberculosis_H37Rv TAKAACQVAR----AHGADKVVLAVPIGPDDIVARFAGYADEVVCLATPA
Mb0586c|M.bovis_AF2122/97 TAKAACQVAR----AHGADKVVLAVPIGPDDIVARFAGYADEVVCLATPA
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2069|M.marinum_M TAAAACQVAR----AQGASRVILAVPIGATDTAPRFTEYADEVVCLETPT
MUL_3276|M.ulcerans_Agy99 TAAAACQVAR----AQGASRVILAVPIGATDTAPRFTEYADEVVCLETPT
TH_3117|M.thermoresistible__bu TAKAACQVVR----AEGAARVVLAVPVGPPDVAERFAGYADEVVCLQTPP
Mflv_4988|M.gilvum_PYR-GCK SMFAAVQALQ----EMDPAEVVIAVPAAPESTCREFAAIVDDVVCASMPT
MAV_2347|M.avium_104 SMLAAVRALRSGPTGATPRSIVVAVPVGPESACRELGREADEVVCLSTPP
MSMEG_4215|M.smegmatis_MC2_155 SMMAAVRAVR------GARRVVVAVPVGPPGVCRELAAEADDVVCASMPQ
MAB_4659|M.abscessus_ATCC_1997 TMRVALLTVKR----ASPARVVAAVPVAPRSAVGRFGSLVDDFVVATCPS
Rv0571c|M.tuberculosis_H37Rv LFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEV
Mb0586c|M.bovis_AF2122/97 LFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEV
Mvan_1399|M.vanbaalenii_PYR-1 -------------------------------------------------M
MMAR_2069|M.marinum_M PYFAVGQGYDNFTQTSDQEVVTLLDRARSEFGAG---HQPPVPARRDDEV
MUL_3276|M.ulcerans_Agy99 PYFAVGQGYDNFTQTSDQEVVTLLDRARSEFGAG---HQPPVPARRDDGV
TH_3117|M.thermoresistible__bu FFSAVGQGYRNFTQTSDDEVIALLRRARADVADTAAADIGDPPPLRDEEV
Mflv_4988|M.gilvum_PYR-GCK PFLAVGESFWDFRQVTDDEVRELLETPTVGFATARIRLAETPAEVIDRCA
MAV_2347|M.avium_104 GFEAVGQVYGDFHQVSDDEVRELLATPTG---------------------
MSMEG_4215|M.smegmatis_MC2_155 DFEAVGQAFADFHQVSDDEVRELLATPTTDPVR-----------------
MAB_4659|M.abscessus_ATCC_1997 RFQAVGDAYRDFHQISDREVRELLSAPVIR--------------------
Rv0571c|M.tuberculosis_H37Rv QVVAGPVPVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGF
Mb0586c|M.bovis_AF2122/97 QVVAGPVPVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGF
Mvan_1399|M.vanbaalenii_PYR-1 RVSTAAADLDGYLTVPENARGVVVFAHGSGSSRHSIRNRYVAKVLNEAGL
MMAR_2069|M.marinum_M RVLAGPVSVIGRLTIPDRPTGIVVFAHGSGSSRHSPRNRYVAEVLNQAGL
MUL_3276|M.ulcerans_Agy99 RVLAGPASVIGRLTIPDRPTGIVVFAHGSGSSRHSPRNRYVAEVLNQAGL
TH_3117|M.thermoresistible__bu RVDAGGVTVTGHLTVPGQPIGVVVFAHGSG--RHSPRNRYVADVLRRAGL
Mflv_4988|M.gilvum_PYR-GCK VDAPAGVPPLEALDELIGDARIVLIGESSHGTEEFYAARAEITKWLIEEK
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0571c|M.tuberculosis_H37Rv ATLLFDLLTPEEERNRAN--------------------------------
Mb0586c|M.bovis_AF2122/97 ATLLFDLLTPEEERNRAN--------------------------------
Mvan_1399|M.vanbaalenii_PYR-1 ATLLFDLLTPAEEADRAN--------------------------------
MMAR_2069|M.marinum_M ATLLLDLLTPEEEHNRAN--------------------------------
MUL_3276|M.ulcerans_Agy99 ATLLLDLLTPEEEHNRAN--------------------------------
TH_3117|M.thermoresistible__bu ATLLFDLLTPDEELDRAN--------------------------------
Mflv_4988|M.gilvum_PYR-GCK GFCGVAAEADWPDAYRVNRYVRGQAGDGSAEEALRGFERFPAWMWRNTVV
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0571c|M.tuberculosis_H37Rv ------------------------------------VFDIELLASRLIDV
Mb0586c|M.bovis_AF2122/97 ------------------------------------VFDIELLASRLIDV
Mvan_1399|M.vanbaalenii_PYR-1 ------------------------------------VFDIDLLAGRLVDV
MMAR_2069|M.marinum_M ------------------------------------VFDIGLLARRLVDV
MUL_3276|M.ulcerans_Agy99 ------------------------------------VFDIGLLARRLVDV
TH_3117|M.thermoresistible__bu ------------------------------------VFDIGLLAERLVGV
Mflv_4988|M.gilvum_PYR-GCK RDFVAWLRACNADRRAQGRREAGFYGLDLYSLHRSMQEVIDFLDRVDPDA
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0571c|M.tuberculosis_H37Rv TGWLATQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDL
Mb0586c|M.bovis_AF2122/97 TGWLATQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDL
Mvan_1399|M.vanbaalenii_PYR-1 TLWLAGRPDLAVLPVGYFGASTGAGAALTAAADRRVDIAAVVSRGGRPDL
MMAR_2069|M.marinum_M TGWLAAQPDTTALPVGFFGASTGAGAALVAAAHPGVKVQAVVSRGGRPDL
MUL_3276|M.ulcerans_Agy99 TGWLAAQPDTTALPVGFFGASTGGGAALVAAAHPGVKVQAVVSRGGRPDL
TH_3117|M.thermoresistible__bu TQWLAAQPETAALPVGYFGASTGAGAALVAAADPRVQVAAVVSRGGRPDL
Mflv_4988|M.gilvum_PYR-GCK AQRARERYSCFDHSSGDDGQAYGFAAAFGAGLSCEHQAVEQLVEMHRSAV
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0571c|M.tuberculosis_H37Rv AGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLF
Mb0586c|M.bovis_AF2122/97 AGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLF
Mvan_1399|M.vanbaalenii_PYR-1 AGVHLGAVTAPTLLIVGSRDEVVLELNQRAQAAMSAECTIAVVPGATHLF
MMAR_2069|M.marinum_M AGDALREVHAPTLLIVGGRDEAVLELNRQAQAAIPAPCELVVVPGATHLF
MUL_3276|M.ulcerans_Agy99 AGDALREVHAPTLPIVGGRDEAVLELNRQAQAAIPAPCELVVVPGATHLF
TH_3117|M.thermoresistible__bu AGQALGKVRAPTLLIVGGRDRFVLELNHQARAAIPAVCEIAVIPGATHLF
Mflv_4988|M.gilvum_PYR-GCK EYARRDGLLAEDELFYAQQNAQTVRDAEVYYRSMFGGRVTSWNLRDRHMA
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0571c|M.tuberculosis_H37Rv EEPGTLEQVAKLACDWFIDHLCGPGPSG----------------------
Mb0586c|M.bovis_AF2122/97 EEPGTLEQVAKLACDWFIDHLCGPGPSG----------------------
Mvan_1399|M.vanbaalenii_PYR-1 EEPGTLEQAAALARDWFVRHLGTPG--G----------------------
MMAR_2069|M.marinum_M EEPGALEQVATLARDWFLGHLRHH--------------------------
MUL_3276|M.ulcerans_Agy99 EEPGALEQVATLARDWFLGHLRHH--------------------------
TH_3117|M.thermoresistible__bu EEPGALDQVAELARDWFTDHLSRTGASTRP--------------------
Mflv_4988|M.gilvum_PYR-GCK ETLEALLRHLDRQGGSEPARIVVWAHNSHVGDARATEVGADGQLTLGQLA
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0571c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0586c|M.bovis_AF2122/97 --------------------------------------------------
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2069|M.marinum_M --------------------------------------------------
MUL_3276|M.ulcerans_Agy99 --------------------------------------------------
TH_3117|M.thermoresistible__bu --------------------------------------------------
Mflv_4988|M.gilvum_PYR-GCK REKFGDHVRLIGYTTYTGTVTAASEWGGLAERKAVRPALNGSVEELFHEV
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0571c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0586c|M.bovis_AF2122/97 --------------------------------------------------
Mvan_1399|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2069|M.marinum_M --------------------------------------------------
MUL_3276|M.ulcerans_Agy99 --------------------------------------------------
TH_3117|M.thermoresistible__bu --------------------------------------------------
Mflv_4988|M.gilvum_PYR-GCK DRPAFLVSPLISHAAAEPLDAVRLGRAIGVIYLPATERQSHYYHVRPSEQ
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0571c|M.tuberculosis_H37Rv -----------------------------------
Mb0586c|M.bovis_AF2122/97 -----------------------------------
Mvan_1399|M.vanbaalenii_PYR-1 -----------------------------------
MMAR_2069|M.marinum_M -----------------------------------
MUL_3276|M.ulcerans_Agy99 -----------------------------------
TH_3117|M.thermoresistible__bu -----------------------------------
Mflv_4988|M.gilvum_PYR-GCK FDGIIHIDRTTALEPLEVTSTWAAGETPETYPTGL
MAV_2347|M.avium_104 -----------------------------------
MSMEG_4215|M.smegmatis_MC2_155 -----------------------------------
MAB_4659|M.abscessus_ATCC_1997 -----------------------------------