For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VKLLSPLDQMFARMEAPRTPMHIGAFAIFDMPKNAPRGFIRDLYEAVSQLAFLPFPFDSVIVGGPSMAYW KQVQPDPSSHVRMSALPQPGTARDLGALVERLHSTPLDMTKPLWELHVIEGLEGKQFAIYFKAHHCAVDG MGGVNLIKSWLTTDPTAPPGSGKPEPLGDDYDLATVFAATTAKRAVEGVSAVSELIGKIISMALGANSSV RAALTTPGTPFNTRINRHRRLAVQVLSLPRLKAVSSATGTTINDVVLASIGGACRHYLRDQSALPKSNLT VSVPVGFERDADTVNAASGFVTQLGTSVEDPIERLTTISASTSRGKAELLALSPNALQHYSVFGLLPIAV GQKSGALGIIPPLFNFTVSNVVLSKEPLYLSGAKLDVIVPMSFLCDGYGLNVTLVGYTDKVVLGFLGCRD TLPHLQRLARYTGEAFDELETATTTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2706 | - | - | 100% (446) | hypothetical protein MUL_2706 |
| M. ulcerans Agy99 | MUL_2057 | - | 6e-66 | 34.98% (466) | hypothetical protein MUL_2057 |
| M. ulcerans Agy99 | MUL_4351 | - | 3e-64 | 34.71% (461) | hypothetical protein MUL_4351 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2306 | - | 0.0 | 85.97% (442) | hypothetical protein Mb2306 |
| M. gilvum PYR-GCK | Mflv_1058 | - | 8e-79 | 39.74% (463) | hypothetical protein Mflv_1058 |
| M. tuberculosis H37Rv | Rv2285 | - | 0.0 | 85.97% (442) | hypothetical protein Rv2285 |
| M. leprae Br4923 | MLBr_01244 | - | 3e-21 | 29.31% (348) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 1e-58 | 31.63% (449) | hypothetical protein MAB_4544c |
| M. marinum M | MMAR_3431 | - | 0.0 | 99.10% (446) | hypothetical protein MMAR_3431 |
| M. avium 104 | MAV_0355 | - | 7e-67 | 35.36% (461) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 7e-67 | 35.82% (455) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 2e-62 | 34.51% (455) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_5773 | - | 5e-78 | 39.22% (464) | hypothetical protein Mvan_5773 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2706|M.ulcerans_Agy99 ----MKLLSPLDQM----FARMEAPRTPMHIGAFAIFDMP-KNAPRGFIR
MMAR_3431|M.marinum_M ----MKLLSPLDQM----FARMEAPRTPMHIGAFAIFDMP-KNAPRGFIR
Mb2306|M.bovis_AF2122/97 ----MKLLSPLDQM----FARMEAPRTPMHIGAFAVFDLP-KGAPRRFIR
Rv2285|M.tuberculosis_H37Rv ----MKLLSPLDQM----FARMEAPRTPMHIGAFAVFDLP-KGAPRRFIR
Mflv_1058|M.gilvum_PYR-GCK MSANSVRLGLQDLM----FIYGETSSSKMHVGGLLPFTPP-ADAPRDYLR
Mvan_5773|M.vanbaalenii_PYR-1 -------------M----FIYGETSSSKMHVAGLLPFTPP-ADAPRDYLR
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPP-DDAGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPP-EGAGRNFVR
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPP-VDAGPDYAE
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFR
: : . ..: . .
MUL_2706|M.ulcerans_Agy99 DLYEAVSQLAFLPFPFDSVIVG-----GPSMAYWKQVQPDPSSHVRMSAL
MMAR_3431|M.marinum_M DLYEAVSQLAFLPFPFDSVIAG-----GPSMAYWKQVQPDPSYHVRMSAL
Mb2306|M.bovis_AF2122/97 DLYEAISQLAFLPFPFDSVIAG-----GASMAYWRQVQPDPSYHVRLSAL
Rv2285|M.tuberculosis_H37Rv DLYEAISQLAFLPFPFDSVIAG-----GASMAYWRQVQPDPSYHVRLSAL
Mflv_1058|M.gilvum_PYR-GCK GMIDEARRQEVVA-PWNRRLAYPRLQFSPLHSWVTDEDFDFDYHVRRSAL
Mvan_5773|M.vanbaalenii_PYR-1 RMVDDARRQEVMP-PWNRKLAYPRLQFSPLHTWVTDTEFDFDYHVRRSAL
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVRHTDFQPVFRKHPATL-LGGIANVGWTLDDEVDLDYHLRRSAL
TH_2030|M.thermoresistible__bu GLHQRLAAGRELHPTFRKHPATL-FGGIAHLGWAVDDDVDFDYHLRRSAL
MAV_0355|M.avium_104 DFYKQLVAQPDFQPTFRKHPAKF-VGGIANLGWSYDADVDVDYHVRRSAL
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMSTTEVSSDFRKRPGQP-LAVMGNLTWIVDDEVDWEYHVRRSAL
MLBr_01244|M.leprae_Br4923 SRIEDVSQRVLRLRQKVVVPTLP----TAAPRWVVDPDFELDFHVRRVRV
. : : : : . *:* :
MUL_2706|M.ulcerans_Agy99 PQPGTARDLGALVERLHSTPLDMTKPLWELHVIEGLEGKQFAIYFKAHHC
MMAR_3431|M.marinum_M PQPGTARDLGALVERLHSTPLDMTKPLWELHVIEGLEGKQFAIYFKAHHC
Mb2306|M.bovis_AF2122/97 PYPGTGRDLGALVERLHSTPLDMAKPLWELHLIEGLTGRQFAMYFKAHHC
Rv2285|M.tuberculosis_H37Rv PYPGTGRDLGALVERLHSTPLDMAKPLWELHLIEGLTGRQFAMYFKAHHC
Mflv_1058|M.gilvum_PYR-GCK ASPGDERELGVLVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHA
Mvan_5773|M.vanbaalenii_PYR-1 ASPGDERELGILVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHA
MSMEG_6322|M.smegmatis_MC2_155 PSPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHS
TH_2030|M.thermoresistible__bu PGPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHA
MAV_0355|M.avium_104 PSPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHA
MAB_4544c|M.abscessus_ATCC_199 PRPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHA
MLBr_01244|M.leprae_Br4923 PDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHA
. * *:: :.. : . :* :* * ::**: : *: : *.
MUL_2706|M.ulcerans_Agy99 AVDGMGGVNLIKSWLTTDPTAP----------PGSGKPEPLGDDYD---L
MMAR_3431|M.marinum_M AVDGMGGVNLIKSWLTTDPTAP----------PGSGKPEPLGDDYD---L
Mb2306|M.bovis_AF2122/97 AVDGLGGVNLIKSWLTTDPEAP----------PGSGKPEPFGDDYD---L
Rv2285|M.tuberculosis_H37Rv AVDGLGGVNLIKSWLTTDPEAP----------PGSGKPEPFGDDYD---L
Mflv_1058|M.gilvum_PYR-GCK LVDGYSAMRMLGRSLSTDPASRDTRMFFNVPSPTRSRRDPGAAESSNPLT
Mvan_5773|M.vanbaalenii_PYR-1 LVDGYTAMRMLGRSLSTDPETRDARMFFNVPIPKRSRPTGAGAQSSNPVT
MSMEG_6322|M.smegmatis_MC2_155 LIDGVSAMKLVERTLSEDPSDTT---------VRVPWNLPRRESSRRAGS
TH_2030|M.thermoresistible__bu LIDGVAVMKLMQRTLSTDPGDD----------ARVPWNLPPPRRNP-AGP
MAV_0355|M.avium_104 LIDGVSAQKLMQRALSSDPDDPE---------IRAPWTLP--KRSRKAGP
MAB_4544c|M.abscessus_ATCC_199 VIDGVGALRMMMRSLSDDPDARD---------CQAVWAPAKRRAKSSIVS
MLBr_01244|M.leprae_Br4923 ITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPV
** .:. :
MUL_2706|M.ulcerans_Agy99 ATVFAATTAKRAVEG-VSAVSELIGKIISMAL---GANSSVRAALTTPGT
MMAR_3431|M.marinum_M ATVFAATTAKRAVEG-VSAVSELIGKIISMAR---GANSSVRAALTTPGT
Mb2306|M.bovis_AF2122/97 ASVLAAATTKRAVEG-VSAVSELAGRLSSMVL---GANSSVRAALTTPRT
Rv2285|M.tuberculosis_H37Rv ASVLAAATTKRAVEG-VSAVSELAGRLSSMVL---GANSSVRAALTTPRT
Mflv_1058|M.gilvum_PYR-GCK ATLRALGGVSSAVTGGVSSAVDLTNALVNTQIRRDGENAHIAGSVSAPHS
Mvan_5773|M.vanbaalenii_PYR-1 ATLRALGAVGSTVSDGVGSAVDLASALVNTQIRRDGDFGRISGSASAPHS
MSMEG_6322|M.smegmatis_MC2_155 SS------LARTATGAATSLAALAPSTIRLAR-AALLEQQLTLPFGAPRT
TH_2030|M.thermoresistible__bu VS------RLRSATGAVGSVAALAPSTLSLAR-AALLEQRLTLPFGAPRT
MAV_0355|M.avium_104 SS------RLSSLVHAAGSVAALAPSTVSLAR-AALVEQQLTLPFGAPRT
MAB_4544c|M.abscessus_ATCC_199 TTNTSAIDLVKGAAGAVRQVVSIPPGLLKYGR-HALSDPQLVKPLSAPHT
MLBr_01244|M.leprae_Br4923 ALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAEPSP
. : * .
MUL_2706|M.ulcerans_Agy99 PFNTRINRHRRLAVQVLSLPRLKAVSSATGTTINDVVLASIGGACRHYLR
MMAR_3431|M.marinum_M PFNTRINRHRRLAVQVLSLPRLKAVSSATGTTINDVVLASIGGACRHYLR
Mb2306|M.bovis_AF2122/97 PFNTRVNRHRRLAVQVLKLPRLKAVAHATDCTVNDVILASVGGACRRYLQ
Rv2285|M.tuberculosis_H37Rv PFNTRVNRHRRLAVQVLKLPRLKAVAHATDCTVNDVILASVGGACRRYLQ
Mflv_1058|M.gilvum_PYR-GCK ILNARISRNRRFATQQYEFDRLKKLSSQHGATLNDVALAIIGGGLRKFLS
Mvan_5773|M.vanbaalenii_PYR-1 ILNARISRNRRFATQQYEFDRLKKLSSQHGATINDVALAIIGGGLRKFLA
MSMEG_6322|M.smegmatis_MC2_155 MFNVKIGGARRVAAQSWPLERLRRIKAVTGATINDIVLAMCAGALRAYLA
TH_2030|M.thermoresistible__bu MFNVRIGGARRVAAQSWPLQRIRRIRQAAGXTLNDVALAMCAGALRQYLL
MAV_0355|M.avium_104 MLNVKIGGARRCAAQSWPLERIKNVKNAAGVTVNDVVLAMCSGALRYYLL
MAB_4544c|M.abscessus_ATCC_199 MLNVSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGALRTYLE
MLBr_01244|M.leprae_Br4923 LLRQRS-LATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHE
:. * . : :: . ::** ** *. * :
MUL_2706|M.ulcerans_Agy99 DQSALPKSNLTVSVPVGFERD-ADT--VNAASGFVTQLGTSVEDPIERLT
MMAR_3431|M.marinum_M DQSALPKSNLTVSVPVGFERD-ADT--VNAASGFVTQLGTSIEDPIERLT
Mb2306|M.bovis_AF2122/97 ELGDLPTNTLTASVPVGFERD-ADT--VNAASGFVAPLGTSIEDPVARLT
Rv2285|M.tuberculosis_H37Rv ELGDLPTNTLTASVPVGFERD-ADT--VNAASGFVAPLGTSIEDPVARLT
Mflv_1058|M.gilvum_PYR-GCK DFDKLPDRSLIAFLPVNVRPK-GDEGGGNAVGAILAPMGTDIEDPVERLD
Mvan_5773|M.vanbaalenii_PYR-1 DLGELPDRSLIAFLPVNVRPK-GDEGGGNAVGAILAPMGTDIEDPVERLA
MSMEG_6322|M.smegmatis_MC2_155 EQDALPDRPLIAMVPVSMRSEHEADAGGNMVGSILCSLGTDVEDPADRLA
TH_2030|M.thermoresistible__bu EHDALPATPLVAMVPVSLRSADESAGGGNRTGLVLCNLATDSDDPAERLD
MAV_0355|M.avium_104 EQNALPDTPLIAMVPVSLRTEEEADAGGNLVGAILCNLATDSDDPAQRLL
MAB_4544c|M.abscessus_ATCC_199 EQNALPDKPLVAMCPVSIRAEGDQNAG-NSITALLANLATDKPDPLERFS
MLBr_01244|M.leprae_Br4923 ALG-VSISTLPMAVPVNVRTEADVVGSNRFVGVTLAAP-LGTNDPAARMQ
. :. * **... . : . ** *:
MUL_2706|M.ulcerans_Agy99 TISASTSRGKAELLALSPNALQHYSVFGLLPIAVG-QKSGALGIIPP---
MMAR_3431|M.marinum_M TISASTSRGKAELLALSPNALQHYSVFGLLPIAVG-QKSGALGIIPP---
Mb2306|M.bovis_AF2122/97 TISASTTRGKAELLAMSPNALQHYSVFGLLPIAVG-QKTGALGVIPP---
Rv2285|M.tuberculosis_H37Rv TISASTTRGKAELLAMSPNALQHYSVFGLLPIAVG-QKTGALGVIPP---
Mflv_1058|M.gilvum_PYR-GCK TITTATRAAKGQLQSMSPAAIIAYSAA-LLAPAGS-QIAGALTGVQPPWP
Mvan_5773|M.vanbaalenii_PYR-1 VITAATRASKAQLQSMSPAAIIAYSAA-LLAPAGG-QIAGALTGVNPPWP
MSMEG_6322|M.smegmatis_MC2_155 VIRRSITDNKRVFSELPRLQALALSALLIAPLGLTTAFPGFVDATAP---
TH_2030|M.thermoresistible__bu RISSSMRSNKRVFSQLPRVQAMALSAAMIAPLGLG-AVPGVVSSAPP---
MAV_0355|M.avium_104 TISESMRSNKKVFSQLPRFQALALSAANLSSLALA-AVPGWVSATSP---
MAB_4544c|M.abscessus_ATCC_199 AIRDSVQAAKSVLSEMTPLQRMLVGALNGAPVLTG-AVPGLVDRTAP---
MLBr_01244|M.leprae_Br4923 KIRSQMTQRR-----DEPAMNIIGSLAPLMTVLPASVLDFIVDSVAS---
* : . . : .
MUL_2706|M.ulcerans_Agy99 -LFNFTVSNVVLSKEPLYLSGAKLDVIVPMS----------FLCDGYGLN
MMAR_3431|M.marinum_M -LFNFTVSNVVLSKEPLYLSGAKLDVIVPMS----------FLCDGYGLN
Mb2306|M.bovis_AF2122/97 -LFNFTVSNVVLSKDPLYLSGAKLDVIVPMS----------FLCDGYGLN
Rv2285|M.tuberculosis_H37Rv -LFNFTVSNVVLSKDPLYLSGAKLDVIVPMS----------FLCDGYGLN
Mflv_1058|M.gilvum_PYR-GCK YTFNLCVSNVPGPREPLYFNGSRLEATYPVS----------IPIHGMALN
Mvan_5773|M.vanbaalenii_PYR-1 HTFNLCVSNVPGPREPLYFNGSRLEATFPVS----------IPIHGMALN
MSMEG_6322|M.smegmatis_MC2_155 -PFNLVISNVPGPKKPLYWRGARLAGNYPLS----------IALDGQALN
TH_2030|M.thermoresistible__bu -PFNLVISNVPGAPEPRYWMGARLAGNYPLS----------IVLDGQALN
MAV_0355|M.avium_104 -PFNIVISNVPGPTAPLYYGGARLDGNYPLS----------IVLDGQALN
MAB_4544c|M.abscessus_ATCC_199 -AFNVIISNVPGPRTDMFWNGFEMDGCYPAS----------IPIDGVALN
MLBr_01244|M.leprae_Br4923 --SDVNASNIPAYPGDTYFAGAKILRQYGIGPRPGVAMMAVLMSRGGFCT
:. **: : * .: . : * .
MUL_2706|M.ulcerans_Agy99 VTLVGYTDKVVLGFLGCRDTLPHLQRLARYTGEAFDELETATTTA-----
MMAR_3431|M.marinum_M VTLVGYTDKVVLGFLGCRDTLPHLQRLARYTGEAFDELETATTTA-----
Mb2306|M.bovis_AF2122/97 VTLVGYTDKVVLGFLGCRDTLPHLQRLAQYTGAAFEELETAALP------
Rv2285|M.tuberculosis_H37Rv VTLVGYTDKVVLGFLGCRDTLPHLQRLAQYTGAAFEELETAALP------
Mflv_1058|M.gilvum_PYR-GCK ITLQSYADTMNLGFVGCRDRLPHLQRLAVYTGDALAELEAASQI------
Mvan_5773|M.vanbaalenii_PYR-1 ITLQSYADTMNLGFVGCRDRLPRLQRLAVYTGDALGELEAASS-------
MSMEG_6322|M.smegmatis_MC2_155 MTVVSNAHNLDFGLVGCRRSVPHLQRLLGHLETSLKDLETATGA------
TH_2030|M.thermoresistible__bu ITLVTNADNLDFGLVGARGSVPHLQRLLGHLEDSLQQLERAVGG------
MAV_0355|M.avium_104 ITLASNAGNLDFGLVGCRRSVPHLQRLLMHLESSLKDLERAVGE------
MAB_4544c|M.abscessus_ATCC_199 ITCTSSGSSMHFGLTGCRTSVPHLQRILAHLEDALTQLEESVA-------
MLBr_01244|M.leprae_Br4923 VTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARSSGS
:* .: .* : ::.: . . :
MUL_2706|M.ulcerans_Agy99 --------
MMAR_3431|M.marinum_M --------
Mb2306|M.bovis_AF2122/97 --------
Rv2285|M.tuberculosis_H37Rv --------
Mflv_1058|M.gilvum_PYR-GCK --------
Mvan_5773|M.vanbaalenii_PYR-1 --------
MSMEG_6322|M.smegmatis_MC2_155 --------
TH_2030|M.thermoresistible__bu --------
MAV_0355|M.avium_104 --------
MAB_4544c|M.abscessus_ATCC_199 --------
MLBr_01244|M.leprae_Br4923 PAGWLSSS