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SGPQGPDPRQSWQPPGQGGDHSSDPTMAAGSPWQQPGQEGSWQPPSYPAADYQQYQQPVEPAYPQQYPAA PGYGQSDFGSQPTRFGAPPQFGQPGQYGQPGQYGQPGQYGQPGQPGQPGQYGQPGQYPGQFSPYDQSGQG SKRSMALIGGVVGGIALLFVVVILVLGFWVPGFFVTTKLDVSKANAGVQQVLTDETNGYGAKNVKDVKCN DGTDPTVKKGATFDCTVSIDGASKHVTVTFQDNKGTYEVGRPQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2323 | - | - | 100% (254) | hypothetical protein MUL_2323 |
| M. ulcerans Agy99 | MUL_0024 | - | 2e-10 | 34.25% (181) | hypothetical protein MUL_0024 |
| M. ulcerans Agy99 | MUL_2957 | - | 1e-08 | 61.36% (44) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2118c | - | 1e-109 | 74.32% (257) | hypothetical protein Mb2118c |
| M. gilvum PYR-GCK | Mflv_3096 | - | 5e-79 | 59.09% (264) | hypothetical protein Mflv_3096 |
| M. tuberculosis H37Rv | Rv2091c | - | 1e-109 | 74.32% (257) | hypothetical protein Rv2091c |
| M. leprae Br4923 | MLBr_01334 | - | 5e-80 | 60.47% (258) | hypothetical protein MLBr_01334 |
| M. abscessus ATCC 19977 | MAB_2190 | - | 1e-65 | 54.02% (261) | hypothetical protein MAB_2190 |
| M. marinum M | MMAR_3077 | - | 1e-156 | 99.61% (254) | hypothetical protein MMAR_3077 |
| M. avium 104 | MAV_2412 | - | 2e-90 | 72.12% (226) | hypothetical protein MAV_2412 |
| M. smegmatis MC2 155 | MSMEG_3884 | - | 5e-79 | 57.35% (279) | hypothetical protein MSMEG_3884 |
| M. thermoresistible (build 8) | TH_1424 | - | 1e-74 | 55.88% (272) | Probable membrane protein |
| M. vanbaalenii PYR-1 | Mvan_3439 | - | 2e-79 | 58.52% (270) | hypothetical protein Mvan_3439 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3096|M.gilvum_PYR-GCK --------------MSGP----QGSDPTQPWSG-----QQPEQGTDQ---
Mvan_3439|M.vanbaalenii_PYR-1 --------------MSGP----QGSDPTQPWPG-----QQPEQGTDQ---
TH_1424|M.thermoresistible__bu --------------MSGP----QGPDPTQPWSG-----Q-PAPGQDQ---
MSMEG_3884|M.smegmatis_MC2_155 MCGNGDSEQDQGEKVSGP----QGSDPAQPWPG-----QQPEPGRDQ---
MUL_2323|M.ulcerans_Agy99 --------------MSGP----QGPDPRQSW-------QPPGQGGD----
MMAR_3077|M.marinum_M --------------MSGP----QGPDPRQSW-------QPPGQGGD----
Mb2118c|M.bovis_AF2122/97 --------------MSGP----QGSDPRQPW-------QPPGQGAD----
Rv2091c|M.tuberculosis_H37Rv --------------MSGP----QGSDPRQPW-------QPPGQGAD----
MAV_2412|M.avium_104 --------------------------------------------------
MLBr_01334|M.leprae_Br4923 --------------MSEP----QGSDPGKQW-------QSPGEGVEN---
MAB_2190|M.abscessus_ATCC_1997 --------------MASLPLMAHKVEQTLRWSVSTLLHTGKKQGRDTGGT
Mflv_3096|M.gilvum_PYR-GCK PAGD-AAANQG-WQPPS----------TEQPAWQPPAYQPQ---QYPQYQ
Mvan_3439|M.vanbaalenii_PYR-1 PAGD-SAANQG-WQPPTPGAGQ----QPEQPSWQPPAYTPQ---QYPQYQ
TH_1424|M.thermoresistible__bu PSGDPTAAGQNPWQPTASGSEQPQAGAEGQQQWQPPAYGQQ---PYPPYQ
MSMEG_3884|M.smegmatis_MC2_155 PAGG------EAWQPPTGGTEEP---TTHNPAWQPPAYTQQPQPQYPQYQ
MUL_2323|M.ulcerans_Agy99 HSSDPTMAAGSPWQQ-----------PGQEGSWQPPSYPAA---DYQQYQ
MMAR_3077|M.marinum_M HSSDPTMAAGSPWQQ-----------PGQEGSWQPPSYPAA---DYQQYQ
Mb2118c|M.bovis_AF2122/97 HSSDPTVAAGYPWQQQ----------PTQEATWQAPAYTP-------QYQ
Rv2091c|M.tuberculosis_H37Rv HSSDPTVAAGYPWQQQ----------PTQEATWQAPAYTP-------QYQ
MAV_2412|M.avium_104 ------MAP--TWQDH----------ATQEASWQAPAYTPPA--EYPQYQ
MLBr_01334|M.leprae_Br4923 HSSDQPTQAASPWQQQP---------STQDSTWHPPAYASP---ECYNYP
MAB_2190|M.abscessus_ATCC_1997 MSGPQGTEPGGQWAPQP---------GQGQDPWQTPQSSDP---AQQGEQ
* : *:.*
Mflv_3096|M.gilvum_PYR-GCK QPTQPPTYSPQQ-YPPGDQYGQP----QTGEYN-PAAYPPP----GQYGQ
Mvan_3439|M.vanbaalenii_PYR-1 QPAQPPTYSPQQ-YP-ADQYGQ-----QPAEYS-PAGYPPP----GQYGQ
TH_1424|M.thermoresistible__bu QPGQP-AYPPP----------------QPTEYN-PAAYGQP----GQPGQ
MSMEG_3884|M.smegmatis_MC2_155 PPAQPGYGQPQQGYPSPEQFGQQPPYGQQPQYGQPGQYGQPS-QPGQYGQ
MUL_2323|M.ulcerans_Agy99 QPVEPAYPQQYP---------------AAPGYGQSD-FGS---QPTRFGA
MMAR_3077|M.marinum_M QPVEPAYPQQYP---------------AAPGYGQSD-FGS---QPTQFGA
Mb2118c|M.bovis_AF2122/97 QPADPAYPQQYPQ--------------PTPGYAQPEQFGA---QPTQLGV
Rv2091c|M.tuberculosis_H37Rv QPADPAYPQQYPQ--------------PTPGYAQPEQFGA---QPTQLGV
MAV_2412|M.avium_104 QPGEQAYPQPYP---------------QQQGYAQPGQYGQYG-QPGQYGQ
MLBr_01334|M.leprae_Br4923 QLTEPVYPHQYPS--------------ATPGYGQPGYFGA---QFSQCGI
MAB_2190|M.abscessus_ATCC_1997 GWQQPAYGQGQQ----------------YPQYQQPGFPGGGFGDPSQFGQ
: * . : *
Mflv_3096|M.gilvum_PYR-GCK Q------PGYGQ---YGQQPQYGQ-PGQYGQ---QPG---QYGQYPGAP-
Mvan_3439|M.vanbaalenii_PYR-1 P------GGYGQ---QYGQP-YGQ-PGQYGQ---QPGQAGQYGQYPGAPG
TH_1424|M.thermoresistible__bu F------GQYGQPPGQFGAPPYGQQPGQFGQ---QPG---QYGQFPPYD-
MSMEG_3884|M.smegmatis_MC2_155 P------GQYPQPGQYGQQPQYGQ-PGQYGQP-GQPG---QYGQPGQFG-
MUL_2323|M.ulcerans_Agy99 PPQFGQPGQYGQP-GQYGQPGQYGQPGQPGQ----PG---QYGQPGQYPG
MMAR_3077|M.marinum_M PPQFGQPGQYGQP-GQYGQPGQYGQPGQPGQ----PG---QYGQPGQYPG
Mb2118c|M.bovis_AF2122/97 P------GQYG----QYQQPGQYGQPGQYGQ----PG---QYAPPGQYPG
Rv2091c|M.tuberculosis_H37Rv P------GQYG----QYQQPGQYGQPGQYGQ----PG---QYAPPGQYPG
MAV_2412|M.avium_104 P------GQYAQP-GQYPQPGQYPQPGQYPQ----PGQYGQYGQPGQYPQ
MLBr_01334|M.leprae_Br4923 P-------------GQYPQSG---SPGQYGP----PG---QYGPPGQYSQ
MAB_2190|M.abscessus_ATCC_1997 QPG----QGFGEP-SQFGQPGAYGQQGQYGQQGAYPG---QYGQPQGQPF
. ** ** **.
Mflv_3096|M.gilvum_PYR-GCK --GYPGQGGDEGSKRSMAVIGGVIGALVAVILAVVLVTGFWKPGFFVTTK
Mvan_3439|M.vanbaalenii_PYR-1 APGYPAPGSEEGSKRSLAVIGGVVGVLAAVVIAAVLVLGFWKPGFFVTTK
TH_1424|M.thermoresistible__bu --AARAEGSGPKSKMLLGVLGGVLG----LVVIAVLVLGLWKPGFLITTK
MSMEG_3884|M.smegmatis_MC2_155 --PYTPPGSADGSKKSLLLFGGLGAA--ALVLIVLAVLFFWVPGWAVTTE
MUL_2323|M.ulcerans_Agy99 -QFSPYDQSGQGSKRSMALIGGVVGGIALLFVVVILVLGFWVPGFFVTTK
MMAR_3077|M.marinum_M -QFSPYDQSGQGSKRSMALIGGVVGGIALLFVVVILVLGFWVPGFFVTTK
Mb2118c|M.bovis_AF2122/97 -QYGPYGQSGQGSKRSVAVIGGVIAVMAVLFIGAVLILGFWAPGFFVTTK
Rv2091c|M.tuberculosis_H37Rv -QYGPYGQSGQGSKRSVAVIGGVIAVMAVLFIGAVLILGFWAPGFFVTTK
MAV_2412|M.avium_104 -QYQPYEQPGK--KRPVGLIAGVAGGIALLLIAVVLVLGFWQPGFFVTTK
MLBr_01334|M.leprae_Br4923 -QFQPYEQPGT--KGFVALIGSIAGVIGVLIFAAILVTGFLWPAWLVTTK
MAB_2190|M.abscessus_ATCC_1997 --PQFGAGKPQRSTKTIAIIGGIVAA--AVVLIVLLVTAFLAPGWAVTTT
. : ::..: . :.. .: : : *.: :**
Mflv_3096|M.gilvum_PYR-GCK LDVDAAQTGVRQILTDETNGYGAKNVNDVTCNGGVSPTVKKGDTFTCEVS
Mvan_3439|M.vanbaalenii_PYR-1 LDVNAAQNGVKQILTDETNGYGATNVNDVKCNNGVSPTVKKGDTFNCEVS
TH_1424|M.thermoresistible__bu LDVNAAQTGVQQILTDETNGYGAKNVRDVVCNDGESPTVKKDTSFTCEVS
MSMEG_3884|M.smegmatis_MC2_155 LDIDKAQTGVQQILTDETNGYGAKNVKDVKCNGGKNPVVKKGDTFTCEVS
MUL_2323|M.ulcerans_Agy99 LDVSKANAGVQQVLTDETNGYGAKNVKDVKCNDGTDPTVKKGATFDCTVS
MMAR_3077|M.marinum_M LDVSKANAGVQQVLTDETNGYGAKNVKDVKCNDGTDPTVKKGATFDCTVS
Mb2118c|M.bovis_AF2122/97 LDVIKAQAGVQQVLTDETTGYGAKNVKDVKCNNGSDPTVKKGATFECTVS
Rv2091c|M.tuberculosis_H37Rv LDVIKAQAGVQQVLTDETTGYGAKNVKDVKCNNGSDPTVKKGATFECTVS
MAV_2412|M.avium_104 LDVNKAQAGVQQVLSDETNGYGAKNVKDVKCNHGQNPTVKKGATFDCDVS
MLBr_01334|M.leprae_Br4923 LDVNKAQASVQQVLTDETNGYGAKNVKDVKCNNGADPTVKKGDTFDCSVS
MAB_2190|M.abscessus_ATCC_1997 LDVNKAQDGVTKILTDETNGYGAKNVKDVKCNDGNNPEVKKGATFTCDVS
**: *: .* ::*:***.****.**.** ** * .* ***. :* * **
Mflv_3096|M.gilvum_PYR-GCK IDGTKRQVTVTFQDDDGTYEVGRPR
Mvan_3439|M.vanbaalenii_PYR-1 IDGTKRQVTVTFQDDNGTYEVGRPK
TH_1424|M.thermoresistible__bu IDGTKRRVTVTFLDDDGTYQVGRPQ
MSMEG_3884|M.smegmatis_MC2_155 IDGTKRQVTVTFQNDDGTYEVGRPK
MUL_2323|M.ulcerans_Agy99 IDGASKHVTVTFQDNKGTYEVGRPQ
MMAR_3077|M.marinum_M IDGASKHVTVTFQDNKGTYEVGRPQ
Mb2118c|M.bovis_AF2122/97 IDGTSKRVTVTFQDNKGTYEVGRPQ
Rv2091c|M.tuberculosis_H37Rv IDGTSKRVTVTFQDNKGTYEVGRPQ
MAV_2412|M.avium_104 IDGAPKHVTVTFQDNKGTYEVGRPQ
MLBr_01334|M.leprae_Br4923 IDGMQKRVTVTFQDDKGTYEVGRPQ
MAB_2190|M.abscessus_ATCC_1997 IDGTKRQVTVTFQNDKGTYEVGRPK
*** ::***** ::.***:****: