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SGPQGSDPTQPWPGQQPEQGTDQPAGDSAANQGWQPPTPGAGQQPEQPSWQPPAYTPQQYPQYQQPAQPP TYSPQQYPADQYGQQPAEYSPAGYPPPGQYGQPGGYGQQYGQPYGQPGQYGQQPGQAGQYGQYPGAPGAP GYPAPGSEEGSKRSLAVIGGVVGVLAAVVIAAVLVLGFWKPGFFVTTKLDVNAAQNGVKQILTDETNGYG ATNVNDVKCNNGVSPTVKKGDTFNCEVSIDGTKRQVTVTFQDDNGTYEVGRPK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3439 | - | - | 100% (264) | hypothetical protein Mvan_3439 |
| M. vanbaalenii PYR-1 | Mvan_0029 | - | 9e-12 | 34.53% (139) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4486 | - | 8e-08 | 29.67% (209) | hypothetical protein Mvan_4486 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2118c | - | 5e-77 | 60.59% (269) | hypothetical protein Mb2118c |
| M. gilvum PYR-GCK | Mflv_3096 | - | 1e-125 | 79.78% (267) | hypothetical protein Mflv_3096 |
| M. tuberculosis H37Rv | Rv2091c | - | 5e-77 | 60.59% (269) | hypothetical protein Rv2091c |
| M. leprae Br4923 | MLBr_01334 | - | 5e-62 | 48.72% (273) | hypothetical protein MLBr_01334 |
| M. abscessus ATCC 19977 | MAB_2190 | - | 3e-64 | 52.04% (269) | hypothetical protein MAB_2190 |
| M. marinum M | MMAR_3077 | - | 2e-79 | 58.52% (270) | hypothetical protein MMAR_3077 |
| M. avium 104 | MAV_2412 | - | 2e-69 | 61.16% (224) | hypothetical protein MAV_2412 |
| M. smegmatis MC2 155 | MSMEG_3884 | - | 1e-91 | 63.70% (281) | hypothetical protein MSMEG_3884 |
| M. thermoresistible (build 8) | TH_1424 | - | 1e-82 | 60.14% (276) | Probable membrane protein |
| M. ulcerans Agy99 | MUL_2323 | - | 2e-79 | 58.52% (270) | hypothetical protein MUL_2323 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3439|M.vanbaalenii_PYR-1 --------------MSGP----QGSDPTQPWPG-----QQPEQGTDQ---
Mflv_3096|M.gilvum_PYR-GCK --------------MSGP----QGSDPTQPWSG-----QQPEQGTDQ---
TH_1424|M.thermoresistible__bu --------------MSGP----QGPDPTQPWSG-----Q-PAPGQDQ---
MSMEG_3884|M.smegmatis_MC2_155 MCGNGDSEQDQGEKVSGP----QGSDPAQPWPG-----QQPEPGRDQ---
Mb2118c|M.bovis_AF2122/97 --------------MSGP----QGSDPRQPW-------QPPGQGAD----
Rv2091c|M.tuberculosis_H37Rv --------------MSGP----QGSDPRQPW-------QPPGQGAD----
MMAR_3077|M.marinum_M --------------MSGP----QGPDPRQSW-------QPPGQGGD----
MUL_2323|M.ulcerans_Agy99 --------------MSGP----QGPDPRQSW-------QPPGQGGD----
MAV_2412|M.avium_104 --------------------------------------------------
MLBr_01334|M.leprae_Br4923 --------------MSEP----QGSDPGKQW-------QSPGEGVEN---
MAB_2190|M.abscessus_ATCC_1997 --------------MASLPLMAHKVEQTLRWSVSTLLHTGKKQGRDTGGT
Mvan_3439|M.vanbaalenii_PYR-1 PAGD-SAANQG-WQPPTPGAGQ----QPEQPSWQPPAYTPQ---QYPQYQ
Mflv_3096|M.gilvum_PYR-GCK PAGD-AAANQG-WQPPS----------TEQPAWQPPAYQPQ---QYPQYQ
TH_1424|M.thermoresistible__bu PSGDPTAAGQNPWQPTASGSEQPQAGAEGQQQWQPPAYGQQ---PYPPYQ
MSMEG_3884|M.smegmatis_MC2_155 PAGG------EAWQPPTGGTEEP---TTHNPAWQPPAYTQQPQPQYPQYQ
Mb2118c|M.bovis_AF2122/97 HSSDPTVAAGYPWQQQ----------PTQEATWQAPAYTP-------QYQ
Rv2091c|M.tuberculosis_H37Rv HSSDPTVAAGYPWQQQ----------PTQEATWQAPAYTP-------QYQ
MMAR_3077|M.marinum_M HSSDPTMAAGSPWQQ-----------PGQEGSWQPPSYPAA---DYQQYQ
MUL_2323|M.ulcerans_Agy99 HSSDPTMAAGSPWQQ-----------PGQEGSWQPPSYPAA---DYQQYQ
MAV_2412|M.avium_104 ------MAP--TWQDH----------ATQEASWQAPAYTPPA--EYPQYQ
MLBr_01334|M.leprae_Br4923 HSSDQPTQAASPWQQQP---------STQDSTWHPPAYASP---ECYNYP
MAB_2190|M.abscessus_ATCC_1997 MSGPQGTEPGGQWAPQP---------GQGQDPWQTPQSSDP---AQQGEQ
* : *:.*
Mvan_3439|M.vanbaalenii_PYR-1 QPAQPPTYSPQQ-YP-ADQYGQ-----QPAEYS-PAGYPPP----GQYGQ
Mflv_3096|M.gilvum_PYR-GCK QPTQPPTYSPQQ-YPPGDQYGQP----QTGEYN-PAAYPPP----GQYGQ
TH_1424|M.thermoresistible__bu QPGQP-AYPPP----------------QPTEYN-PAAYGQP----GQPGQ
MSMEG_3884|M.smegmatis_MC2_155 PPAQPGYGQPQQGYPSPEQFGQQPPYGQQPQYGQPGQYGQPS-QPGQYGQ
Mb2118c|M.bovis_AF2122/97 QPADPAYPQQYPQ--------------PTPGYAQPEQFGA---QPTQLGV
Rv2091c|M.tuberculosis_H37Rv QPADPAYPQQYPQ--------------PTPGYAQPEQFGA---QPTQLGV
MMAR_3077|M.marinum_M QPVEPAYPQQYP---------------AAPGYGQSD-FGS---QPTQFGA
MUL_2323|M.ulcerans_Agy99 QPVEPAYPQQYP---------------AAPGYGQSD-FGS---QPTRFGA
MAV_2412|M.avium_104 QPGEQAYPQPYP---------------QQQGYAQPGQYGQYG-QPGQYGQ
MLBr_01334|M.leprae_Br4923 QLTEPVYPHQYPS--------------ATPGYGQPGYFGA---QFSQCGI
MAB_2190|M.abscessus_ATCC_1997 GWQQPAYGQGQQ----------------YPQYQQPGFPGGGFGDPSQFGQ
: * . : *
Mvan_3439|M.vanbaalenii_PYR-1 P------GGYGQ---QYGQP-YGQ-PGQYGQ---QPGQAGQYGQYPGAPG
Mflv_3096|M.gilvum_PYR-GCK Q------PGYGQ---YGQQPQYGQ-PGQYGQ---QPG---QYGQYP---G
TH_1424|M.thermoresistible__bu F------GQYGQPPGQFGAPPYGQQPGQFGQ---QPG---QYGQFP---P
MSMEG_3884|M.smegmatis_MC2_155 P------GQYPQPGQYGQQPQYGQ-PGQYGQP-GQPG---QYGQPG---Q
Mb2118c|M.bovis_AF2122/97 P------GQYG----QYQQPGQYGQPGQYGQ----PG---QYAPPG---Q
Rv2091c|M.tuberculosis_H37Rv P------GQYG----QYQQPGQYGQPGQYGQ----PG---QYAPPG---Q
MMAR_3077|M.marinum_M PPQFGQPGQYGQP-GQYGQPGQYGQPGQPGQ----PG---QYGQPG---Q
MUL_2323|M.ulcerans_Agy99 PPQFGQPGQYGQP-GQYGQPGQYGQPGQPGQ----PG---QYGQPG---Q
MAV_2412|M.avium_104 P------GQYAQP-GQYPQPGQYPQPGQYPQ----PGQYGQYGQPG---Q
MLBr_01334|M.leprae_Br4923 P-------------GQYPQSG---SPGQYGP----PG---QYGPPG---Q
MAB_2190|M.abscessus_ATCC_1997 QPG----QGFGEP-SQFGQPGAYGQQGQYGQQGAYPG---QYGQPQG--Q
. ** ** **.
Mvan_3439|M.vanbaalenii_PYR-1 APGYPAPGSEEGS--KRSLAVIGGVVGVLAAVVIAAVLVLGFWKPGFFVT
Mflv_3096|M.gilvum_PYR-GCK APGYPGQGGDEGS--KRSMAVIGGVIGALVAVILAVVLVTGFWKPGFFVT
TH_1424|M.thermoresistible__bu YDAARAEGSGPKS--KMLLGVLGGVLG----LVVIAVLVLGLWKPGFLIT
MSMEG_3884|M.smegmatis_MC2_155 FGPYTPPGSADGS--KKSLLLFGGLGAA--ALVLIVLAVLFFWVPGWAVT
Mb2118c|M.bovis_AF2122/97 YPGQYGPYGQSGQGSKRSVAVIGGVIAVMAVLFIGAVLILGFWAPGFFVT
Rv2091c|M.tuberculosis_H37Rv YPGQYGPYGQSGQGSKRSVAVIGGVIAVMAVLFIGAVLILGFWAPGFFVT
MMAR_3077|M.marinum_M YPGQFSPYDQSGQGSKRSMALIGGVVGGIALLFVVVILVLGFWVPGFFVT
MUL_2323|M.ulcerans_Agy99 YPGQFSPYDQSGQGSKRSMALIGGVVGGIALLFVVVILVLGFWVPGFFVT
MAV_2412|M.avium_104 YPQQYQPYEQPGK--KRPVGLIAGVAGGIALLLIAVVLVLGFWQPGFFVT
MLBr_01334|M.leprae_Br4923 YSQQFQPYEQPGT--KGFVALIGSIAGVIGVLIFAAILVTGFLWPAWLVT
MAB_2190|M.abscessus_ATCC_1997 PFPQFGAGKPQRS--TKTIAIIGGIVAA--AVVLIVLLVTAFLAPGWAVT
. : ::..: . :.. .: : : *.: :*
Mvan_3439|M.vanbaalenii_PYR-1 TKLDVNAAQNGVKQILTDETNGYGATNVNDVKCNNGVSPTVKKGDTFNCE
Mflv_3096|M.gilvum_PYR-GCK TKLDVDAAQTGVRQILTDETNGYGAKNVNDVTCNGGVSPTVKKGDTFTCE
TH_1424|M.thermoresistible__bu TKLDVNAAQTGVQQILTDETNGYGAKNVRDVVCNDGESPTVKKDTSFTCE
MSMEG_3884|M.smegmatis_MC2_155 TELDIDKAQTGVQQILTDETNGYGAKNVKDVKCNGGKNPVVKKGDTFTCE
Mb2118c|M.bovis_AF2122/97 TKLDVIKAQAGVQQVLTDETTGYGAKNVKDVKCNNGSDPTVKKGATFECT
Rv2091c|M.tuberculosis_H37Rv TKLDVIKAQAGVQQVLTDETTGYGAKNVKDVKCNNGSDPTVKKGATFECT
MMAR_3077|M.marinum_M TKLDVSKANAGVQQVLTDETNGYGAKNVKDVKCNDGTDPTVKKGATFDCT
MUL_2323|M.ulcerans_Agy99 TKLDVSKANAGVQQVLTDETNGYGAKNVKDVKCNDGTDPTVKKGATFDCT
MAV_2412|M.avium_104 TKLDVNKAQAGVQQVLSDETNGYGAKNVKDVKCNHGQNPTVKKGATFDCD
MLBr_01334|M.leprae_Br4923 TKLDVNKAQASVQQVLTDETNGYGAKNVKDVKCNNGADPTVKKGDTFDCS
MAB_2190|M.abscessus_ATCC_1997 TTLDVNKAQDGVTKILTDETNGYGAKNVKDVKCNDGNNPEVKKGATFTCD
* **: *: .* ::*:***.****.**.** ** * .* ***. :* *
Mvan_3439|M.vanbaalenii_PYR-1 VSIDGTKRQVTVTFQDDNGTYEVGRPK
Mflv_3096|M.gilvum_PYR-GCK VSIDGTKRQVTVTFQDDDGTYEVGRPR
TH_1424|M.thermoresistible__bu VSIDGTKRRVTVTFLDDDGTYQVGRPQ
MSMEG_3884|M.smegmatis_MC2_155 VSIDGTKRQVTVTFQNDDGTYEVGRPK
Mb2118c|M.bovis_AF2122/97 VSIDGTSKRVTVTFQDNKGTYEVGRPQ
Rv2091c|M.tuberculosis_H37Rv VSIDGTSKRVTVTFQDNKGTYEVGRPQ
MMAR_3077|M.marinum_M VSIDGASKHVTVTFQDNKGTYEVGRPQ
MUL_2323|M.ulcerans_Agy99 VSIDGASKHVTVTFQDNKGTYEVGRPQ
MAV_2412|M.avium_104 VSIDGAPKHVTVTFQDNKGTYEVGRPQ
MLBr_01334|M.leprae_Br4923 VSIDGMQKRVTVTFQDDKGTYEVGRPQ
MAB_2190|M.abscessus_ATCC_1997 VSIDGTKRQVTVTFQNDKGTYEVGRPK
***** ::***** ::.***:****: