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GSQKGLVQRIERKLESTVGDAFARMFGGSIVPQEVEALLRREAADGVRSLPGNRLLAPNEYIITLSVHDA EELGADPHLTSSEFARYLADYIHEQGWQTYADVVVRFEQSSSLHTGQFRARGAVNPDVEPRPTVNDSAQP QSNDAFGAEPGVPPMTDNSSYRGGQGQGRPDEYYDERYARPQEDPRGGPHGGPDPRGGYPPEAGGYPPQP GYPPPRPQDQGGYPEQGGYPDQRGYPDQRGYQDQRGYPDQRDYQDQGGYPDQRGYPEQGGYPPSYEQCPP APGGYGAQGYDQGYRQGGGYGQPPGGQPGYGGYGEYGREPARQDEGAYSAPAAPSAPPEAQRPGYPDQGG GYDQGYQQGGAGYGRPEYGQGDYTQYADTSSPGGYPPQGAGYADPAGRDYEYGQAAAPDYGQAPPDYGQP AGGGYGGYGQSGYGAAGSSVILQLDDGSGRTYQLRDGSNIIGRGQDAQFRLPDTGVSRRHLEIRWDGQVA LLADLNSTNGTTVNNAPVQEWQLADGDVIRLGHSEIIVRIH*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_0024 | - | - | 100% (532) | hypothetical protein MUL_0024 |
M. ulcerans Agy99 | MUL_3149 | - | 3e-11 | 27.82% (248) | transmembrane ATP-binding protein ABC transporter |
M. ulcerans Agy99 | MUL_3046 | - | 6e-10 | 32.32% (99) | hypothetical protein MUL_3046 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0020c | TB39.8 | 0.0 | 77.82% (541) | hypothetical protein Mb0020c |
M. gilvum PYR-GCK | Mflv_0806 | - | 1e-165 | 59.96% (542) | FHA domain-containing protein |
M. tuberculosis H37Rv | Rv0020c | TB39.8 | 0.0 | 79.48% (541) | hypothetical protein Rv0020c |
M. leprae Br4923 | MLBr_00022 | - | 0.0 | 71.29% (533) | hypothetical protein MLBr_00022 |
M. abscessus ATCC 19977 | MAB_0039c | - | 1e-119 | 50.94% (532) | hypothetical protein MAB_0039c |
M. marinum M | MMAR_0022 | - | 0.0 | 95.79% (546) | hypothetical protein MMAR_0022 |
M. avium 104 | MAV_0024 | - | 0.0 | 73.20% (556) | xyppx repeat-containing protein |
M. smegmatis MC2 155 | MSMEG_0035 | - | 1e-177 | 62.11% (549) | FHA domain-containing protein |
M. thermoresistible (build 8) | TH_2237 | - | 1e-177 | 61.61% (560) | CONSERVED HYPOTHETICAL PROTEIN TB39.8 |
M. vanbaalenii PYR-1 | Mvan_0029 | - | 1e-168 | 61.31% (535) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0806|M.gilvum_PYR-GCK ------MGLVDRFERKLEDSVGDAFARVFGGSIVPREVEVLLRREAETGA Mvan_0029|M.vanbaalenii_PYR-1 ------MGLVGRFERKLEDKVGDAFARVFGGSIVPQEVESLLRREADAGV TH_2237|M.thermoresistible__bu ------MGLADRIERKLEATVGDAFARVFGGSIVPQEVEARLRREAQAGA MSMEG_0035|M.smegmatis_MC2_155 MKAGDVMGLVDRIERKLESTVGDAFARVFGGSIVPQEVEVALRREAETRA MUL_0024|M.ulcerans_Agy99 --MGSQKGLVQRIERKLESTVGDAFARMFGGSIVPQEVEALLRREAADGV MMAR_0022|M.marinum_M --MGSQKGLVQRIERKLESTVGDAFARMFGGSIVPQEVEALLRREAADGV Mb0020c|M.bovis_AF2122/97 --MGSQKRLVQRVERKLEQTVGDAFARIFGGSIVPQEVEALLRREAADRI Rv0020c|M.tuberculosis_H37Rv --MGSQKRLVQRVERKLEQTVGDAFARIFGGSIVPQEVEALLRREAADGI MLBr_00022|M.leprae_Br4923 --MDNQKELIQRIERKLESSIDDAFARMFGGSIVPQEVEALLRREASDGV MAV_0024|M.avium_104 --MSSQRGLVARIERKLEATVDNAFARVFGGPIVPQEVEALLCREARDGV MAB_0039c|M.abscessus_ATCC_199 ------MGIVQRFERKLEDVVGDAFARVFGGSIVPQEVQASLRREAADGV : *.***** :.:****:***.***:**: * *** Mflv_0806|M.gilvum_PYR-GCK RKVPGGHILAPNDYVITLSVPDFQKVNADPDITATTFAKHLEGYIHEQGW Mvan_0029|M.vanbaalenii_PYR-1 RELHGGRILAPNDYVITLSVPDYRKVSADPDITATTFAKHLEGYIHEQGW TH_2237|M.thermoresistible__bu RDVGGGRILAPNDYVITLSESDYRKVSADPDRTSTTFAKHLEGYIHDQGW MSMEG_0035|M.smegmatis_MC2_155 RTVAGGQVLAPNDYVITLSGTDYQKVRADTDLTSTTFAKHLKGYIHDQGW MUL_0024|M.ulcerans_Agy99 RSLPGNRLLAPNEYIITLSVHDAEELGADPHLTSSEFARYLADYIHEQGW MMAR_0022|M.marinum_M RSLPGNRLLAPNEYIITLSVHDAEELGADPHLTSSEFARYLADYIHEQGW Mb0020c|M.bovis_AF2122/97 QSLQGNRLLAPNEYIITLGVHDFEKLGADPELKSTGFARDLADYIQEQGW Rv0020c|M.tuberculosis_H37Rv QSLQGNRLLAPNEYIITLGVHDFEKLGADPELKSTGFARDLADYIQEQGW MLBr_00022|M.leprae_Br4923 RSLQGNRLLAPNEYIITLGVHDLEKMKADPDLTSSAFASDLADYIHEQGW MAV_0024|M.avium_104 QKLHGNRLLAPNEYIITLGMHDFEKVSADPDLTSSAFARYLADYIHEQGW MAB_0039c|M.abscessus_ATCC_199 RSAGQGRLLAPNEFFVLLSTADHEKAADDRDLNPDTFAELLREYIRDQGW : .::****::.: *. * .: * . .. ** * **::*** Mflv_0806|M.gilvum_PYR-GCK QTYGDVVVRFEQSPNLHTGQFRARGAVNPDA----TTVEPAPPSRDATSQ Mvan_0029|M.vanbaalenii_PYR-1 QTYGDVVVRFEQSPNLHTGQFRARAAVNPDA----TTVEPAPPPRDVTSQ TH_2237|M.thermoresistible__bu QTYGDVVVRFEQSSNLHTGQFRARGLVNPDT----TTGEPAQAQQDRAYT MSMEG_0035|M.smegmatis_MC2_155 QTYGEVVVRFEQSPNLHTGQFRARGAVNPDS----TAGESARAPRDHAFT MUL_0024|M.ulcerans_Agy99 QTYADVVVRFEQSSSLHTGQFRARGAVNPDVEPRPTVNDSAQPQSNDAFG MMAR_0022|M.marinum_M QTYGDVVVRFEQSSSLHTGQFRARGAVNPDVEPRPTVNDSAQPQSNDAFG Mb0020c|M.bovis_AF2122/97 QTYGDVVVRFEQSSNLHTGQFRARGTVNPDVETHPPVIDCARPQSNHAFG Rv0020c|M.tuberculosis_H37Rv QTYGDVVVRFEQSSNLHTGQFRARGTVNPDVETHPPVIDCARPQSNHAFG MLBr_00022|M.leprae_Br4923 QTYGDVVVRFDQSSSLHTGQIRARSVVNPDVEPRPTVNDPVRTQSNQAFS MAV_0024|M.avium_104 QTYGEVVVRFEQSSSLRTGQYRACGAVNPDVQPRPTVDDPVRPQSNNAFG MAB_0039c|M.abscessus_ATCC_199 QTYGEVVVRFEQSPNLHTGQFRTRGVVNPDS--KRDRPHGAVTTAPPTPD ***.:*****:**..*:*** *: . **** . . . : Mflv_0806|M.gilvum_PYR-GCK AEPGVPAMTDNPSYRGGPGQGRP-DEY--YN----RPPENRPEDEGGYNR Mvan_0029|M.vanbaalenii_PYR-1 AEPGVPPMTDNPTYRGGQGPGRPADDY--YN----RPEDERP-------- TH_2237|M.thermoresistible__bu AEPGVPPMSDNPSYRGGQGPGRPADDE--YDDRYGRPDDPRGQ----YPP MSMEG_0035|M.smegmatis_MC2_155 AESGEPPMTDNPNYRGGQGPARPGDEY--YDERYGRQDDPRG-------- MUL_0024|M.ulcerans_Agy99 AEPGVPPMTDNSSYRGGQGQGRPDE-Y--YDERYARPQEDPRGGP----- MMAR_0022|M.marinum_M AEPGVPPMTDNSSYRGGQGQGRPDE-Y--YDERYARPQEDPRGGP----- Mb0020c|M.bovis_AF2122/97 AEPGVAPMSDNSSYRGGQGQGRPDE-Y--YDDRYARPQEDPRGGPD---- Rv0020c|M.tuberculosis_H37Rv AEPGVAPMSDNSSYRGGQGQGRPDE-Y--YDDRYARPQEDPRGGPD---- MLBr_00022|M.leprae_Br4923 AEPGVPPMTDNSSYRGGQGQGRPS------DDYYGRPQDDPRGAD----- MAV_0024|M.avium_104 EERGVAPMTDNSSYRGAQGPGRPGDEY--YDERYGRPQDDARGGSE---- MAB_0039c|M.abscessus_ATCC_199 PQPG-APMTDNP----GPQQGRPGEEYGREDDRYGRPDQDPR-------- : * ..*:**. . .** : * : Mflv_0806|M.gilvum_PYR-GCK PENRGDEQRGGYPHGDQGGYP--AQDQGYP-----PRGGYPEQG------ Mvan_0029|M.vanbaalenii_PYR-1 --NRGDEPRGGYPPADQGGYPPPADQGGYP-----PRGGYPEHGGYPEHG TH_2237|M.thermoresistible__bu ADQGGYPPRGGYPEQPGGGYP--EQQGGYPE----QQGGYPDQGGYPPRG MSMEG_0035|M.smegmatis_MC2_155 --GQYPPEQGGYPPQDQGGYP--PRGGGYP-----DQGGYPDQG------ MUL_0024|M.ulcerans_Agy99 --HGGPDPRGGYPP-EAGGYP---PQPGYPPPRPQDQGGYPEQGGYPDQR MMAR_0022|M.marinum_M --HGGPDPRGGYPP-EAGGYP---PQPGYPPPRPQDQGGYPEQGGYPEQG Mb0020c|M.bovis_AF2122/97 -PQGGSDPRGGYPP-ETGGYP---PQPGYPRPRHPGQGDYPEQIGYPDQG Rv0020c|M.tuberculosis_H37Rv -PQGGSDPRGGYPP-ETGGYP---PQPGYPRPRHPDQGDYPEQIGYPDQG MLBr_00022|M.leprae_Br4923 -PQGGQDPRGCYPP-KPGSYP---QQAGHPPLHRPDQGGYPGQGGYE--- MAV_0024|M.avium_104 -PQGAPDQRGGYPP-EQGGYP---PQQGYPPPRHPEQGGYPEQGGYPPPQ MAB_0039c|M.abscessus_ATCC_199 ----GQQPQG------GQGYP--PRQGGYE------GGGYGQGQ------ :* .** *: *.* Mflv_0806|M.gilvum_PYR-GCK GYQDQGGYQ---------GQGGYP--------------------PQSYEQ Mvan_0029|M.vanbaalenii_PYR-1 GYPDQGGYP---------EQGGYP--------------------PQSYEQ TH_2237|M.thermoresistible__bu GYPDQGGYP---------EQGGYPDQG---------------GYPPSYEQ MSMEG_0035|M.smegmatis_MC2_155 GYPDQGGYP---------DQGGYP--------------------PQSYEQ MUL_0024|M.ulcerans_Agy99 GYPDQRGYQDQRG---YPDQRDYQDQG-GYPDQRGYPE--QGGYPPSYEQ MMAR_0022|M.marinum_M GYPDQRGYQDQRG---YQDQRGYPDQG-GYPDQRGYPE--QGGYPPSYEQ Mb0020c|M.bovis_AF2122/97 GYPEQRGYP---------DQRGHQDQGRGYPDQG------QGGYPPPYEQ Rv0020c|M.tuberculosis_H37Rv GYPEQRGYPEQRG---YPDQRGYQDQGRGYPDQG------QGGYPPPYEQ MLBr_00022|M.leprae_Br4923 ------------------DQRAYHDQG-------------QGGYPSPYEQ MAV_0024|M.avium_104 SYQEHGGYPDQRGGYPEPGQAGYPPQQHGYPDLRGYPEPAQGGYPQSYEQ MAB_0039c|M.abscessus_ATCC_199 PYGQDYGRP----------PAGYD--------------------QGGYQQ : *:* Mflv_0806|M.gilvum_PYR-GCK RPPAGYGP---PPG-YPDQGYRQGPGGY-------GPPPGG-----APGY Mvan_0029|M.vanbaalenii_PYR-1 RPPAGYGP---PPGGYPDQGYRQPPPGY-------GPPPGG-----QPGY TH_2237|M.thermoresistible__bu RPPAGYGP---PPGGGYDQGYRQPPPGY-------GPP-GG-----QPGY MSMEG_0035|M.smegmatis_MC2_155 RPPAGYGPP--PQGGGYDRGYGQPAGGYPPAGPPAGPPPGG-----QPGY MUL_0024|M.ulcerans_Agy99 CPPA-PG---GYGAQGYDQGYRQG-GGY-------GQPPGG-----QPGY MMAR_0022|M.marinum_M RPPA-PG---GYGAQGYDQGYRQA-GGY-------GQPPGG-----QPGY Mb0020c|M.bovis_AF2122/97 RPPVSPGPAAGYGAPGYDQGYRQS-GGC-------GPSPGGG----QPGY Rv0020c|M.tuberculosis_H37Rv RPPVSPGPAAGYGAPGYDQGYRQS-GGY-------GPSPGGG----QPGY MLBr_00022|M.leprae_Br4923 RPAT-PG---GYGSQGHDQGYRP--GSY-------GPPSGG-----QPGY MAV_0024|M.avium_104 RPPAPPG----YSGQGYDQGYRPP-GGG-------YPPPGGQPAGGPQGY MAB_0039c|M.abscessus_ATCC_199 RPPQQGG----YDQGGYGAPPQAPQGGGD-----YGRPPAP------PQQ *. * . . . . Mflv_0806|M.gilvum_PYR-GCK GGP-AGDYDYGR----RPDDGGYG-------QPP--RPAYPDQGG-YPDQ Mvan_0029|M.vanbaalenii_PYR-1 GPP-SGDYDYGR----RPDDGGYGP------QGPQGRPSYPDQGG-YPDQ TH_2237|M.thermoresistible__bu GAPPAGEYDYGRPPGGRPDD--YGR------PGHPDQGGYPDQGGGYPDQ MSMEG_0035|M.smegmatis_MC2_155 GGA---DYDYGR---QAPRHDDYGR------PDP--RQGYPEQGG-YPEQ MUL_0024|M.ulcerans_Agy99 GGY--GEYGREP---ARQDEGAYSAPAAPSAPPEAQRPGYPDQGGGYDQG MMAR_0022|M.marinum_M GGY--GEYGREP---ARQDEGAYSAPAAPSAPPEAQRPGYPDQGGGYDQG Mb0020c|M.bovis_AF2122/97 GGY--GEYGRGP---ARHEEGSY-VPSGPPGPPE-QRPAYPDQGG-YDQG Rv0020c|M.tuberculosis_H37Rv GGY--GEYGRGP---ARHEEGSY-VPSGPPGPPE-QRPAYPDQGG-YDQG MLBr_00022|M.leprae_Br4923 GGY--GDYGRGP---ARPDEGSY-TPSGFPAPPE-QRVAYPDQGGGYDQG MAV_0024|M.avium_104 GGY--GDYGRGP---ARPDEGGY-------APPE-QRPAYPEQGGGYDQG MAB_0039c|M.abscessus_ATCC_199 GGG----YGAPP------QQGGYGE------PPRPNYGEY-EQGGGYGGG * *. . * * :*** * Mflv_0806|M.gilvum_PYR-GCK ------GGYGAP-GGQQSYGRQDYAQP-DYGRYGEP-----AGYGDQG-- Mvan_0029|M.vanbaalenii_PYR-1 ------GGY----GGQQ-YGRQDYAQP-DYGRYGEAP----AGYQDQG-- TH_2237|M.thermoresistible__bu GYGDQGGGYPDQGYGDQGYGGQPYGRP-DYGQQPGQ-----GDYGAGG-- MSMEG_0035|M.smegmatis_MC2_155 ------GGY-----GGQAYGRPDYGQP-DYGQQPGRGYPEQGGYPEQGG- MUL_0024|M.ulcerans_Agy99 --------YQ---QGGAGYGRPEYGQG-DYTQYADTS--SPGGYPPQGAG MMAR_0022|M.marinum_M --------YQ---QGGAGYGRPEYGQG-DYTQYADTS--SPGGYPPQGAG Mb0020c|M.bovis_AF2122/97 --------YQ---QGATTYGRQDYGGGADYTRYTESP--QVPGYAPQGGG Rv0020c|M.tuberculosis_H37Rv --------YQ---QGATTYGRQDYGGGADYTRYTESP--RVPGYAPQGGG MLBr_00022|M.leprae_Br4923 --------YQ---HSGLGYGREDYGRQ-EYTQYAENL--PGGVYAPSSGG MAV_0024|M.avium_104 --------YP---QGG-GYGRQDYGSA-EYTQYAEHA--QGATYAPPGGG MAB_0039c|M.abscessus_ATCC_199 -------QYG---GQQGPPPGQDYGRPPAYPQQGGYG------APPQQGG * *. * : Mflv_0806|M.gilvum_PYR-GCK YGEQGYGDQGYGD-------QGYGAPA-----------------GQQGGY Mvan_0029|M.vanbaalenii_PYR-1 YGEP----AGYQD-------PGY---------------------GQGGSY TH_2237|M.thermoresistible__bu YGDAGGYGAGYGD-------PGRGDYD-----------------YAGAGY MSMEG_0035|M.smegmatis_MC2_155 YGEPAGRDYEYG--------GDYGAPA-----------------GQGGYG MUL_0024|M.ulcerans_Agy99 YADPAGRDYEYGQ----AAAPDYGQAPPDY--------------GQPAG- MMAR_0022|M.marinum_M YADPAGRDYEYCQ----AAAPDYGQAPPDYGQAPSDYGQAPPEYGQPAG- Mb0020c|M.bovis_AF2122/97 YAEPAGRDYDYGQ----SGAPDY---------------------GQPAP- Rv0020c|M.tuberculosis_H37Rv YAEPAGRDYDYGQ----SGAPDY---------------------GQPAP- MLBr_00022|M.leprae_Br4923 YAEPAGRDYDYGQP---GAANDY---------------------SQPVI- MAV_0024|M.avium_104 YPEAPGSEYEYGQPADYGQQPEYAQP---------------AEYGQPADY MAB_0039c|M.abscessus_ATCC_199 YGSPEYGDYEQGG-------------------------------YQSSP- * . Mflv_0806|M.gilvum_PYR-GCK ----GGYGAG-QGDYPAG----ATVTLQLDDGSGRTYQLREGANVIGRGQ Mvan_0029|M.vanbaalenii_PYR-1 ----AGYGA--QGDYPAAG---ATVTLQLDDGSGRTYQLREGANVIGRGQ TH_2237|M.thermoresistible__bu GQD-AGYGRQ-DYQQPPATGRPTTVTLQLDDGSGRTYQLREGANVIGRGQ MSMEG_0035|M.smegmatis_MC2_155 ----GGYGA----DYPAGG---TTVTLQLDDGSGRTYQLREGANVIGRGQ MUL_0024|M.ulcerans_Agy99 ----GGYGGYGQSGYGAAG---SSVILQLDDGSGRTYQLRDGSNIIGRGQ MMAR_0022|M.marinum_M ----GGYGGYGQSGYGAAG---SSVILQLDDGSGRTYQLRDGSNIIGRGQ Mb0020c|M.bovis_AF2122/97 ----GGYSGYGQGGYGSAG---TSVTLQLDDGSGRTYQLREGSNIIGRGQ Rv0020c|M.tuberculosis_H37Rv ----GGYSGYGQGGYGSAG---TSVTLQLDDGSGRTYQLREGSNIIGRGQ MLBr_00022|M.leprae_Br4923 ----GGYG-----GYGALG---SAVILQLDDGSGRTYQLREGSNIVGRGQ MAV_0024|M.avium_104 GQQAGGYGGYGQGGYGSTG---TTVTLQLDDGSGRTYQLREGSNIIGRGQ MAB_0039c|M.abscessus_ATCC_199 -----DYGAP-AGGPGGGR---TTVTLQLDDGSGRTYQLREGTNVIGRGQ .*. ::* **************:*:*::**** Mflv_0806|M.gilvum_PYR-GCK DAQFRLPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLAD Mvan_0029|M.vanbaalenii_PYR-1 DAQFRLPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLAD TH_2237|M.thermoresistible__bu DAQFRLPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLAD MSMEG_0035|M.smegmatis_MC2_155 DAQFRLPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLAD MUL_0024|M.ulcerans_Agy99 DAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLAD MMAR_0022|M.marinum_M DAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLAD Mb0020c|M.bovis_AF2122/97 DAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLAD Rv0020c|M.tuberculosis_H37Rv DAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLAD MLBr_00022|M.leprae_Br4923 DAQFRLPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLAD MAV_0024|M.avium_104 DAQFRLPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLAD MAB_0039c|M.abscessus_ATCC_199 DAQFRLPDTGVSRRHLEVRFDGHAALLSDLNSTNGTTVNNAPVTEWQLAD *****************:*:**:.***:*************** ****** Mflv_0806|M.gilvum_PYR-GCK GDVIRLGHSEIIVRVH Mvan_0029|M.vanbaalenii_PYR-1 GDVIRLGHSEIIVRVH TH_2237|M.thermoresistible__bu GDVIRLGHSEIIVRMH MSMEG_0035|M.smegmatis_MC2_155 GDVIRLGHSEIIVRVH MUL_0024|M.ulcerans_Agy99 GDVIRLGHSEIIVRIH MMAR_0022|M.marinum_M GDVIRLGHSEIIVRIH Mb0020c|M.bovis_AF2122/97 GDVIRLGHSEIIVRMH Rv0020c|M.tuberculosis_H37Rv GDVIRLGHSEIIVRMH MLBr_00022|M.leprae_Br4923 GDVIRLGHSEIIVRIH MAV_0024|M.avium_104 GDVIRLGHSEIIVRIH MAB_0039c|M.abscessus_ATCC_199 GDIIRLGHSEIIVRVQ **:***********::