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M. ulcerans Agy99 MUL_1779 (pyrR)

annotation: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase
coordinates: 1966139 - 1966702
length: 187

MGAANDAVDGRELMSAAVVGRTISRIAHQIIEKTALDSPDSPRVVLLGIPTRGVILASRLAANIGEYSGI
EVDHGALDITLYRDDLMSKPPRPLEETEIPAGGVDDALVILVDDVLYSGRSVRSALDALRDVGRPRSVQL
AVLVDRGHRELPVRADYVGKNVPTARSESVHVQFSEHDGHDGVVISR

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. ulcerans Agy99 MUL_1779 pyrR - 100% (187) bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1414 pyrR 4e-85 84.46% (193) bifunctional pyrimidine regulatory protein PyrR uracil
M. gilvum PYR-GCK Mflv_3748 - 4e-77 75.81% (186) pyrimidine regulatory protein PyrR
M. tuberculosis H37Rv Rv1379 pyrR 4e-85 84.46% (193) bifunctional pyrimidine regulatory protein PyrR uracil
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_2832c - 6e-72 78.29% (175) PyrR bifunctional protein (pyrimidine operon regulatory
M. marinum M MMAR_2194 pyrR 1e-101 99.47% (187) pyrimidine operon regulatory protein PyrR
M. avium 104 MAV_3394 - 3e-86 84.74% (190) pyrimidine regulatory protein PyrR
M. smegmatis MC2 155 MSMEG_3042 - 2e-78 83.15% (178) pyrimidine regulatory protein PyrR
M. thermoresistible (build 8) TH_1352 pyrR 3e-80 79.79% (188) PROBABLE PYRIMIDINE OPERON REGULATORY PROTEIN PYRR
M. vanbaalenii PYR-1 Mvan_2659 - 3e-78 76.88% (186) pyrimidine regulatory protein PyrR

CLUSTAL 2.0.9 multiple sequence alignment


MUL_1779|M.ulcerans_Agy99           MGAANDAVDG---RELMSAAVVGRTISRIAHQIIEKTALD---SPDSPRV
MMAR_2194|M.marinum_M               MGAANDAVDG---RELMSAADVGRTISRIAHQIIEKTALD---SPDSPRV
Mb1414|M.bovis_AF2122/97            MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRV
Rv1379|M.tuberculosis_H37Rv         MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRV
MAV_3394|M.avium_104                MGAAGNTGSSGDSRELMSAADVGRTVSRIAHQIIEKTALD---GPDGPRV
MSMEG_3042|M.smegmatis_MC2_155      -----MGS-SSTDRELLSAADVGRTVSRIAHQIIEKTALDD--PAERTRV
TH_1352|M.thermoresistible__bu      --VGSMADGSDAARELLSAADVGRTISRIAHQIIEKTALDG--P-DAPRV
MAB_2832c|M.abscessus_ATCC_199      ---------------MLSAADVGRTISRIAHQIIEKTALSD--SGDAPRV
Mflv_3748|M.gilvum_PYR-GCK          ---MGAPDQSGSDRELMSAADVSRTIARIAHQIIEKTALD---GPDGPRV
Mvan_2659|M.vanbaalenii_PYR-1       ---MGAPDQTGPDRELMSAADVSRTIARIAHQIIEKTALD---GPDGPRV
                                                   ::*** *.**::************.     : .**

MUL_1779|M.ulcerans_Agy99           VLLGIPTRGVILASRLAANIGEYSGIEVDHGALDITLYRDDLMSKPPRPL
MMAR_2194|M.marinum_M               VLLGIPTRGVILASRLAANIGEYSGIEVDHGALDITLYRDDLMSKPPRPL
Mb1414|M.bovis_AF2122/97            VLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPL
Rv1379|M.tuberculosis_H37Rv         VLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPL
MAV_3394|M.avium_104                VLLGIPTRGVTLADRLARNIGEYSGVEVGHGALDITLYRDDLMQKPPRPL
MSMEG_3042|M.smegmatis_MC2_155      VLLGIPTRGVILATRLAAKIKEFAGEDVPHGALDITLYRDDLNFKPPRPL
TH_1352|M.thermoresistible__bu      VLLGIPTRGVTLADRLATKIREFSGVQVPHGALDITLYRDDLNIKPPRPL
MAB_2832c|M.abscessus_ATCC_199      VLVGIPTRGATLAKRLAAHITEFSGVEVPAGFLDITLYRDDLRNKPHRPL
Mflv_3748|M.gilvum_PYR-GCK          ILLGIPTRGVTLASRLATNIAEFSGVQVAHGALDTTLYRDDLMTKPPRAL
Mvan_2659|M.vanbaalenii_PYR-1       ILLGIPTRGVTLATRLARNIAEFSGVEVAHGALDITLYRDDLMTKPPRAL
                                    :*:******. ** *** :* *::* .*  * ** *******  ** *.*

MUL_1779|M.ulcerans_Agy99           EETEIPAGGVDDALVILVDDVLYSGRSVRSALDALRDVGRPRSVQLAVLV
MMAR_2194|M.marinum_M               EETEIPAGGVDDALVILVDDVLYSGRSVRSALDALRDVGRPRSVQLAVLV
Mb1414|M.bovis_AF2122/97            ASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLV
Rv1379|M.tuberculosis_H37Rv         ASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLV
MAV_3394|M.avium_104                EATSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRVVQLAVLV
MSMEG_3042|M.smegmatis_MC2_155      EATSIPAGGVDDAIVILVDDVLYSGRSVRSALDALRDIGRPRIVQLAVLV
TH_1352|M.thermoresistible__bu      EDTTIPEGGIDDALVILVDDVLFSGRSVRSALDALRDIGRPRAVQLAVLV
MAB_2832c|M.abscessus_ATCC_199      ERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRDLGRPRAVQLAVLV
Mflv_3748|M.gilvum_PYR-GCK          AETSIPAGGIDGALVILVDDVLYTGRSVRSALDALRDLGRPKAVQLAVLV
Mvan_2659|M.vanbaalenii_PYR-1       AATSIPEGGIDGALVVLVDDVLYSGRSVRSALDALRDLGRPKSVQLAVLV
                                      * ** **:*.*:*:******::**:**********:***: *******

MUL_1779|M.ulcerans_Agy99           DRGHRELPVRADYVGKNVPTARSESVHVQFSEHDGHDGVVISR------
MMAR_2194|M.marinum_M               DRGHRELPVRADYVGKNVPTARSESVHVQFSEHDGHDGVVISR------
Mb1414|M.bovis_AF2122/97            DRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR------
Rv1379|M.tuberculosis_H37Rv         DRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR------
MAV_3394|M.avium_104                DRGHRELPLRAEYVGKNVPTSRSESVHVLLAEHDGADGVVISR------
MSMEG_3042|M.smegmatis_MC2_155      DRGHRELPIRADYVGKNVPTSRSESVHVLLSEHDDRDGVVISK------
TH_1352|M.thermoresistible__bu      DRGHRELPLRADYVGKNVPTSRSESVRVLLREHDDRDGVVISR------
MAB_2832c|M.abscessus_ATCC_199      DRGHRELPLRADYVGKNVPTARSEDVKVLLAEHDGRDAVIITSGQGAQT
Mflv_3748|M.gilvum_PYR-GCK          DRGHRELPIRADYVGKNVPTSRSENVKVRLTENDGVDIIAIAPYGGPPR
Mvan_2659|M.vanbaalenii_PYR-1       DRGHRELPIRADYVGKNVPTSRAENVKVRLTEDDGHDGVRIAPYGGPAR
                                    ********:**:********:*:*.*:* : *.*. * : *:

species	id	gene	e-value	identity (len)	annotation
M. ulcerans Agy99	MUL_1779	pyrR	-	100% (187)	bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase