For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_3042 (-)

annotation: pyrimidine regulatory protein PyrR
coordinates: 3115075 - 3115632
length: 185

MGSSSTDRELLSAADVGRTVSRIAHQIIEKTALDDPAERTRVVLLGIPTRGVILATRLAAKIKEFAGEDV
PHGALDITLYRDDLNFKPPRPLEATSIPAGGVDDAIVILVDDVLYSGRSVRSALDALRDIGRPRIVQLAV
LVDRGHRELPIRADYVGKNVPTSRSESVHVLLSEHDDRDGVVISK

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. smegmatis MC2 155 MSMEG_3042 - - 100% (185) pyrimidine regulatory protein PyrR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1414 pyrR 1e-79 82.78% (180) bifunctional pyrimidine regulatory protein PyrR uracil
M. gilvum PYR-GCK Mflv_3748 - 4e-71 75.14% (181) pyrimidine regulatory protein PyrR
M. tuberculosis H37Rv Rv1379 pyrR 1e-79 82.78% (180) bifunctional pyrimidine regulatory protein PyrR uracil
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_2832c - 1e-72 77.71% (175) PyrR bifunctional protein (pyrimidine operon regulatory
M. marinum M MMAR_2194 pyrR 2e-79 83.71% (178) pyrimidine operon regulatory protein PyrR
M. avium 104 MAV_3394 - 2e-81 83.15% (184) pyrimidine regulatory protein PyrR
M. thermoresistible (build 8) TH_1352 pyrR 2e-82 84.62% (182) PROBABLE PYRIMIDINE OPERON REGULATORY PROTEIN PYRR
M. ulcerans Agy99 MUL_1779 pyrR 1e-78 83.15% (178) bifunctional pyrimidine regulatory protein PyrR uracil
M. vanbaalenii PYR-1 Mvan_2659 - 2e-72 77.53% (178) pyrimidine regulatory protein PyrR

CLUSTAL 2.0.9 multiple sequence alignment


Mb1414|M.bovis_AF2122/97            MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRV
Rv1379|M.tuberculosis_H37Rv         MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRV
MAV_3394|M.avium_104                MGAAGNTGSSGDSRELMSAADVGRTVSRIAHQIIEKTALD---GPDGPRV
MMAR_2194|M.marinum_M               MGAANDAVDG---RELMSAADVGRTISRIAHQIIEKTALD---SPDSPRV
MUL_1779|M.ulcerans_Agy99           MGAANDAVDG---RELMSAAVVGRTISRIAHQIIEKTALD---SPDSPRV
MSMEG_3042|M.smegmatis_MC2_155      -----MGS-SSTDRELLSAADVGRTVSRIAHQIIEKTALDD--PAERTRV
TH_1352|M.thermoresistible__bu      --VGSMADGSDAARELLSAADVGRTISRIAHQIIEKTALDG--P-DAPRV
MAB_2832c|M.abscessus_ATCC_199      ---------------MLSAADVGRTISRIAHQIIEKTALSD--SGDAPRV
Mflv_3748|M.gilvum_PYR-GCK          ---MGAPDQSGSDRELMSAADVSRTIARIAHQIIEKTALD---GPDGPRV
Mvan_2659|M.vanbaalenii_PYR-1       ---MGAPDQTGPDRELMSAADVSRTIARIAHQIIEKTALD---GPDGPRV
                                                   ::*** *.**::************.     : .**

Mb1414|M.bovis_AF2122/97            VLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPL
Rv1379|M.tuberculosis_H37Rv         VLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPL
MAV_3394|M.avium_104                VLLGIPTRGVTLADRLARNIGEYSGVEVGHGALDITLYRDDLMQKPPRPL
MMAR_2194|M.marinum_M               VLLGIPTRGVILASRLAANIGEYSGIEVDHGALDITLYRDDLMSKPPRPL
MUL_1779|M.ulcerans_Agy99           VLLGIPTRGVILASRLAANIGEYSGIEVDHGALDITLYRDDLMSKPPRPL
MSMEG_3042|M.smegmatis_MC2_155      VLLGIPTRGVILATRLAAKIKEFAGEDVPHGALDITLYRDDLNFKPPRPL
TH_1352|M.thermoresistible__bu      VLLGIPTRGVTLADRLATKIREFSGVQVPHGALDITLYRDDLNIKPPRPL
MAB_2832c|M.abscessus_ATCC_199      VLVGIPTRGATLAKRLAAHITEFSGVEVPAGFLDITLYRDDLRNKPHRPL
Mflv_3748|M.gilvum_PYR-GCK          ILLGIPTRGVTLASRLATNIAEFSGVQVAHGALDTTLYRDDLMTKPPRAL
Mvan_2659|M.vanbaalenii_PYR-1       ILLGIPTRGVTLATRLARNIAEFSGVEVAHGALDITLYRDDLMTKPPRAL
                                    :*:******. ** *** :* *::* .*  * ** *******  ** *.*

Mb1414|M.bovis_AF2122/97            ASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLV
Rv1379|M.tuberculosis_H37Rv         ASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLV
MAV_3394|M.avium_104                EATSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRVVQLAVLV
MMAR_2194|M.marinum_M               EETEIPAGGVDDALVILVDDVLYSGRSVRSALDALRDVGRPRSVQLAVLV
MUL_1779|M.ulcerans_Agy99           EETEIPAGGVDDALVILVDDVLYSGRSVRSALDALRDVGRPRSVQLAVLV
MSMEG_3042|M.smegmatis_MC2_155      EATSIPAGGVDDAIVILVDDVLYSGRSVRSALDALRDIGRPRIVQLAVLV
TH_1352|M.thermoresistible__bu      EDTTIPEGGIDDALVILVDDVLFSGRSVRSALDALRDIGRPRAVQLAVLV
MAB_2832c|M.abscessus_ATCC_199      ERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRDLGRPRAVQLAVLV
Mflv_3748|M.gilvum_PYR-GCK          AETSIPAGGIDGALVILVDDVLYTGRSVRSALDALRDLGRPKAVQLAVLV
Mvan_2659|M.vanbaalenii_PYR-1       AATSIPEGGIDGALVVLVDDVLYSGRSVRSALDALRDLGRPKSVQLAVLV
                                      * ** **:*.*:*:******::**:**********:***: *******

Mb1414|M.bovis_AF2122/97            DRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR------
Rv1379|M.tuberculosis_H37Rv         DRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR------
MAV_3394|M.avium_104                DRGHRELPLRAEYVGKNVPTSRSESVHVLLAEHDGADGVVISR------
MMAR_2194|M.marinum_M               DRGHRELPVRADYVGKNVPTARSESVHVQFSEHDGHDGVVISR------
MUL_1779|M.ulcerans_Agy99           DRGHRELPVRADYVGKNVPTARSESVHVQFSEHDGHDGVVISR------
MSMEG_3042|M.smegmatis_MC2_155      DRGHRELPIRADYVGKNVPTSRSESVHVLLSEHDDRDGVVISK------
TH_1352|M.thermoresistible__bu      DRGHRELPLRADYVGKNVPTSRSESVRVLLREHDDRDGVVISR------
MAB_2832c|M.abscessus_ATCC_199      DRGHRELPLRADYVGKNVPTARSEDVKVLLAEHDGRDAVIITSGQGAQT
Mflv_3748|M.gilvum_PYR-GCK          DRGHRELPIRADYVGKNVPTSRSENVKVRLTENDGVDIIAIAPYGGPPR
Mvan_2659|M.vanbaalenii_PYR-1       DRGHRELPIRADYVGKNVPTSRAENVKVRLTEDDGHDGVRIAPYGGPAR
                                    ********:**:********:*:*.*:* : *.*. * : *:

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_3042	-	-	100% (185)	pyrimidine regulatory protein PyrR