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GAAGNTGSSGDSRELMSAADVGRTVSRIAHQIIEKTALDGPDGPRVVLLGIPTRGVTLADRLARNIGEYS GVEVGHGALDITLYRDDLMQKPPRPLEATSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRVV QLAVLVDRGHRELPLRAEYVGKNVPTSRSESVHVLLAEHDGADGVVISR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3394 | - | - | 100% (190) | pyrimidine regulatory protein PyrR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1414 | pyrR | 1e-89 | 87.05% (193) | bifunctional pyrimidine regulatory protein PyrR uracil |
| M. gilvum PYR-GCK | Mflv_3748 | - | 5e-80 | 79.46% (185) | pyrimidine regulatory protein PyrR |
| M. tuberculosis H37Rv | Rv1379 | pyrR | 1e-89 | 87.05% (193) | bifunctional pyrimidine regulatory protein PyrR uracil |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2832c | - | 3e-73 | 79.43% (175) | PyrR bifunctional protein (pyrimidine operon regulatory |
| M. marinum M | MMAR_2194 | pyrR | 3e-87 | 85.26% (190) | pyrimidine operon regulatory protein PyrR |
| M. smegmatis MC2 155 | MSMEG_3042 | - | 3e-81 | 83.15% (184) | pyrimidine regulatory protein PyrR |
| M. thermoresistible (build 8) | TH_1352 | pyrR | 8e-84 | 86.19% (181) | PROBABLE PYRIMIDINE OPERON REGULATORY PROTEIN PYRR |
| M. ulcerans Agy99 | MUL_1779 | pyrR | 2e-86 | 84.74% (190) | bifunctional pyrimidine regulatory protein PyrR uracil |
| M. vanbaalenii PYR-1 | Mvan_2659 | - | 4e-81 | 81.08% (185) | pyrimidine regulatory protein PyrR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1414|M.bovis_AF2122/97 MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRV
Rv1379|M.tuberculosis_H37Rv MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRV
MAV_3394|M.avium_104 MGAAGNTGSSGDSRELMSAADVGRTVSRIAHQIIEKTALD---GPDGPRV
MMAR_2194|M.marinum_M MGAANDAVDG---RELMSAADVGRTISRIAHQIIEKTALD---SPDSPRV
MUL_1779|M.ulcerans_Agy99 MGAANDAVDG---RELMSAAVVGRTISRIAHQIIEKTALD---SPDSPRV
MSMEG_3042|M.smegmatis_MC2_155 -----MGS-SSTDRELLSAADVGRTVSRIAHQIIEKTALDD--PAERTRV
TH_1352|M.thermoresistible__bu --VGSMADGSDAARELLSAADVGRTISRIAHQIIEKTALDG--P-DAPRV
MAB_2832c|M.abscessus_ATCC_199 ---------------MLSAADVGRTISRIAHQIIEKTALSD--SGDAPRV
Mflv_3748|M.gilvum_PYR-GCK ---MGAPDQSGSDRELMSAADVSRTIARIAHQIIEKTALD---GPDGPRV
Mvan_2659|M.vanbaalenii_PYR-1 ---MGAPDQTGPDRELMSAADVSRTIARIAHQIIEKTALD---GPDGPRV
::*** *.**::************. : .**
Mb1414|M.bovis_AF2122/97 VLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPL
Rv1379|M.tuberculosis_H37Rv VLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPL
MAV_3394|M.avium_104 VLLGIPTRGVTLADRLARNIGEYSGVEVGHGALDITLYRDDLMQKPPRPL
MMAR_2194|M.marinum_M VLLGIPTRGVILASRLAANIGEYSGIEVDHGALDITLYRDDLMSKPPRPL
MUL_1779|M.ulcerans_Agy99 VLLGIPTRGVILASRLAANIGEYSGIEVDHGALDITLYRDDLMSKPPRPL
MSMEG_3042|M.smegmatis_MC2_155 VLLGIPTRGVILATRLAAKIKEFAGEDVPHGALDITLYRDDLNFKPPRPL
TH_1352|M.thermoresistible__bu VLLGIPTRGVTLADRLATKIREFSGVQVPHGALDITLYRDDLNIKPPRPL
MAB_2832c|M.abscessus_ATCC_199 VLVGIPTRGATLAKRLAAHITEFSGVEVPAGFLDITLYRDDLRNKPHRPL
Mflv_3748|M.gilvum_PYR-GCK ILLGIPTRGVTLASRLATNIAEFSGVQVAHGALDTTLYRDDLMTKPPRAL
Mvan_2659|M.vanbaalenii_PYR-1 ILLGIPTRGVTLATRLARNIAEFSGVEVAHGALDITLYRDDLMTKPPRAL
:*:******. ** *** :* *::* .* * ** ******* ** *.*
Mb1414|M.bovis_AF2122/97 ASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLV
Rv1379|M.tuberculosis_H37Rv ASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLV
MAV_3394|M.avium_104 EATSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRVVQLAVLV
MMAR_2194|M.marinum_M EETEIPAGGVDDALVILVDDVLYSGRSVRSALDALRDVGRPRSVQLAVLV
MUL_1779|M.ulcerans_Agy99 EETEIPAGGVDDALVILVDDVLYSGRSVRSALDALRDVGRPRSVQLAVLV
MSMEG_3042|M.smegmatis_MC2_155 EATSIPAGGVDDAIVILVDDVLYSGRSVRSALDALRDIGRPRIVQLAVLV
TH_1352|M.thermoresistible__bu EDTTIPEGGIDDALVILVDDVLFSGRSVRSALDALRDIGRPRAVQLAVLV
MAB_2832c|M.abscessus_ATCC_199 ERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRDLGRPRAVQLAVLV
Mflv_3748|M.gilvum_PYR-GCK AETSIPAGGIDGALVILVDDVLYTGRSVRSALDALRDLGRPKAVQLAVLV
Mvan_2659|M.vanbaalenii_PYR-1 AATSIPEGGIDGALVVLVDDVLYSGRSVRSALDALRDLGRPKSVQLAVLV
* ** **:*.*:*:******::**:**********:***: *******
Mb1414|M.bovis_AF2122/97 DRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR------
Rv1379|M.tuberculosis_H37Rv DRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR------
MAV_3394|M.avium_104 DRGHRELPLRAEYVGKNVPTSRSESVHVLLAEHDGADGVVISR------
MMAR_2194|M.marinum_M DRGHRELPVRADYVGKNVPTARSESVHVQFSEHDGHDGVVISR------
MUL_1779|M.ulcerans_Agy99 DRGHRELPVRADYVGKNVPTARSESVHVQFSEHDGHDGVVISR------
MSMEG_3042|M.smegmatis_MC2_155 DRGHRELPIRADYVGKNVPTSRSESVHVLLSEHDDRDGVVISK------
TH_1352|M.thermoresistible__bu DRGHRELPLRADYVGKNVPTSRSESVRVLLREHDDRDGVVISR------
MAB_2832c|M.abscessus_ATCC_199 DRGHRELPLRADYVGKNVPTARSEDVKVLLAEHDGRDAVIITSGQGAQT
Mflv_3748|M.gilvum_PYR-GCK DRGHRELPIRADYVGKNVPTSRSENVKVRLTENDGVDIIAIAPYGGPPR
Mvan_2659|M.vanbaalenii_PYR-1 DRGHRELPIRADYVGKNVPTSRAENVKVRLTEDDGHDGVRIAPYGGPAR
********:**:********:*:*.*:* : *.*. * : *: