For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LSAADVGRTISRIAHQIIEKTALSDSGDAPRVVLVGIPTRGATLAKRLAAHITEFSGVEVPAGFLDITLY RDDLRNKPHRPLERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRDLGRPRAVQLAVLVDRGHRELP LRADYVGKNVPTARSEDVKVLLAEHDGRDAVIITSGQGAQT*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_2832c | - | - | 100% (182) | PyrR bifunctional protein (pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase) |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1414 | pyrR | 2e-73 | 79.10% (177) | bifunctional pyrimidine regulatory protein PyrR uracil |
M. gilvum PYR-GCK | Mflv_3748 | - | 1e-69 | 75.86% (174) | pyrimidine regulatory protein PyrR |
M. tuberculosis H37Rv | Rv1379 | pyrR | 2e-73 | 79.10% (177) | bifunctional pyrimidine regulatory protein PyrR uracil |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | MMAR_2194 | pyrR | 7e-73 | 78.86% (175) | pyrimidine operon regulatory protein PyrR |
M. avium 104 | MAV_3394 | - | 3e-73 | 79.43% (175) | pyrimidine regulatory protein PyrR |
M. smegmatis MC2 155 | MSMEG_3042 | - | 2e-72 | 77.71% (175) | pyrimidine regulatory protein PyrR |
M. thermoresistible (build 8) | TH_1352 | pyrR | 3e-76 | 82.86% (175) | PROBABLE PYRIMIDINE OPERON REGULATORY PROTEIN PYRR |
M. ulcerans Agy99 | MUL_1779 | pyrR | 5e-72 | 78.29% (175) | bifunctional pyrimidine regulatory protein PyrR uracil |
M. vanbaalenii PYR-1 | Mvan_2659 | - | 1e-70 | 78.16% (174) | pyrimidine regulatory protein PyrR |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_3042|M.smegmatis_MC2_155 -----MGS-SSTDRELLSAADVGRTVSRIAHQIIEKTALDD--PAERTRV TH_1352|M.thermoresistible__bu --VGSMADGSDAARELLSAADVGRTISRIAHQIIEKTALDG--P-DAPRV Mb1414|M.bovis_AF2122/97 MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRV Rv1379|M.tuberculosis_H37Rv MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRV MAV_3394|M.avium_104 MGAAGNTGSSGDSRELMSAADVGRTVSRIAHQIIEKTALD---GPDGPRV MMAR_2194|M.marinum_M MGAANDAVDG---RELMSAADVGRTISRIAHQIIEKTALD---SPDSPRV MUL_1779|M.ulcerans_Agy99 MGAANDAVDG---RELMSAAVVGRTISRIAHQIIEKTALD---SPDSPRV MAB_2832c|M.abscessus_ATCC_199 ---------------MLSAADVGRTISRIAHQIIEKTALSD--SGDAPRV Mflv_3748|M.gilvum_PYR-GCK ---MGAPDQSGSDRELMSAADVSRTIARIAHQIIEKTALD---GPDGPRV Mvan_2659|M.vanbaalenii_PYR-1 ---MGAPDQTGPDRELMSAADVSRTIARIAHQIIEKTALD---GPDGPRV ::*** *.**::************. : .** MSMEG_3042|M.smegmatis_MC2_155 VLLGIPTRGVILATRLAAKIKEFAGEDVPHGALDITLYRDDLNFKPPRPL TH_1352|M.thermoresistible__bu VLLGIPTRGVTLADRLATKIREFSGVQVPHGALDITLYRDDLNIKPPRPL Mb1414|M.bovis_AF2122/97 VLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPL Rv1379|M.tuberculosis_H37Rv VLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPL MAV_3394|M.avium_104 VLLGIPTRGVTLADRLARNIGEYSGVEVGHGALDITLYRDDLMQKPPRPL MMAR_2194|M.marinum_M VLLGIPTRGVILASRLAANIGEYSGIEVDHGALDITLYRDDLMSKPPRPL MUL_1779|M.ulcerans_Agy99 VLLGIPTRGVILASRLAANIGEYSGIEVDHGALDITLYRDDLMSKPPRPL MAB_2832c|M.abscessus_ATCC_199 VLVGIPTRGATLAKRLAAHITEFSGVEVPAGFLDITLYRDDLRNKPHRPL Mflv_3748|M.gilvum_PYR-GCK ILLGIPTRGVTLASRLATNIAEFSGVQVAHGALDTTLYRDDLMTKPPRAL Mvan_2659|M.vanbaalenii_PYR-1 ILLGIPTRGVTLATRLARNIAEFSGVEVAHGALDITLYRDDLMTKPPRAL :*:******. ** *** :* *::* .* * ** ******* ** *.* MSMEG_3042|M.smegmatis_MC2_155 EATSIPAGGVDDAIVILVDDVLYSGRSVRSALDALRDIGRPRIVQLAVLV TH_1352|M.thermoresistible__bu EDTTIPEGGIDDALVILVDDVLFSGRSVRSALDALRDIGRPRAVQLAVLV Mb1414|M.bovis_AF2122/97 ASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLV Rv1379|M.tuberculosis_H37Rv ASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLV MAV_3394|M.avium_104 EATSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRVVQLAVLV MMAR_2194|M.marinum_M EETEIPAGGVDDALVILVDDVLYSGRSVRSALDALRDVGRPRSVQLAVLV MUL_1779|M.ulcerans_Agy99 EETEIPAGGVDDALVILVDDVLYSGRSVRSALDALRDVGRPRSVQLAVLV MAB_2832c|M.abscessus_ATCC_199 ERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRDLGRPRAVQLAVLV Mflv_3748|M.gilvum_PYR-GCK AETSIPAGGIDGALVILVDDVLYTGRSVRSALDALRDLGRPKAVQLAVLV Mvan_2659|M.vanbaalenii_PYR-1 AATSIPEGGIDGALVVLVDDVLYSGRSVRSALDALRDLGRPKSVQLAVLV * ** **:*.*:*:******::**:**********:***: ******* MSMEG_3042|M.smegmatis_MC2_155 DRGHRELPIRADYVGKNVPTSRSESVHVLLSEHDDRDGVVISK------ TH_1352|M.thermoresistible__bu DRGHRELPLRADYVGKNVPTSRSESVRVLLREHDDRDGVVISR------ Mb1414|M.bovis_AF2122/97 DRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR------ Rv1379|M.tuberculosis_H37Rv DRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR------ MAV_3394|M.avium_104 DRGHRELPLRAEYVGKNVPTSRSESVHVLLAEHDGADGVVISR------ MMAR_2194|M.marinum_M DRGHRELPVRADYVGKNVPTARSESVHVQFSEHDGHDGVVISR------ MUL_1779|M.ulcerans_Agy99 DRGHRELPVRADYVGKNVPTARSESVHVQFSEHDGHDGVVISR------ MAB_2832c|M.abscessus_ATCC_199 DRGHRELPLRADYVGKNVPTARSEDVKVLLAEHDGRDAVIITSGQGAQT Mflv_3748|M.gilvum_PYR-GCK DRGHRELPIRADYVGKNVPTSRSENVKVRLTENDGVDIIAIAPYGGPPR Mvan_2659|M.vanbaalenii_PYR-1 DRGHRELPIRADYVGKNVPTSRAENVKVRLTEDDGHDGVRIAPYGGPAR ********:**:********:*:*.*:* : *.*. * : *: