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MSTAAEGGAICRAGHEPRYDLAQLPPAPPTTVAVIEGMATGAPQRVVAQADAAARVSELFVDPQQRERIS RIYDKTRIDTRRMAVDPLDDEFDEFRREPATIRDRMNLFYQHAVPLAVDVAARALDGLPYAPDEIGQLVF VTSTGFIAPGVDVEIVKQLGLPRSISRVVVNFMGCAAAMNAIRTATNYVRAHPSMKALVVCIELSSVNAV FADDINDVVIHSLFGDGCGALVIGASQAQQPLPAGNVVIRSSFSQLLDDSEDGIVLGVNHDGITCELSEN LPSYIYRSVDPVVAEMLRDNGLSKADIDLWAIHPGGPKIIEQSARSLGIPVGRAVQSWDVLAQFGNMLSV SLIFVLEMMVAQAESDKPISTGVAFAFAPGVTVEGMLFDIIRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1775 | - | - | 100% (393) | chalcone/stilbene synthase |
| M. ulcerans Agy99 | MUL_1656 | pks11 | 5e-33 | 26.74% (359) | chalcone synthase, Pks11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1406 | - | 1e-173 | 79.39% (393) | hypothetical protein Mb1406 |
| M. gilvum PYR-GCK | Mflv_5140 | - | 5e-37 | 29.44% (360) | chalcone/stilbene synthase domain-containing protein |
| M. tuberculosis H37Rv | Rv1372 | - | 1e-173 | 79.39% (393) | hypothetical protein Rv1372 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1141c | - | 8e-05 | 25.74% (202) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. marinum M | MMAR_2190 | - | 0.0 | 99.49% (393) | chalcone/stilbene synthase |
| M. avium 104 | MAV_3110 | - | 9e-31 | 30.85% (282) | Pks10 protein |
| M. smegmatis MC2 155 | MSMEG_0808 | - | 6e-35 | 27.82% (363) | chalcone synthase Pks10 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1196 | - | 2e-32 | 27.02% (359) | chalcone/stilbene synthase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1775|M.ulcerans_Agy99 MSTAAEGGAICRAGHEPRYDLAQLPPAPPTTVAVIEGMATGAPQRVVAQA
MMAR_2190|M.marinum_M MSTAAEGGAIRRAGHEPRYDLAQLPPAPPTTVAVIEGMATGAPQRVVAQA
Mb1406|M.bovis_AF2122/97 MNVSAESGAPRRAGQRHEVGLAQLPPAPPTTVAVIEGLATGTPRRVVNQS
Rv1372|M.tuberculosis_H37Rv MNVSAESGAPRRAGQRHEVGLAQLPPAPPTTVAVIEGLATGTPRRVVNQS
Mflv_5140|M.gilvum_PYR-GCK ------------------------MTDVHTPVSVIAGVQGALPPHRYSQA
Mvan_1196|M.vanbaalenii_PYR-1 ---------------------------MNDRISVIAGVQGALPPYRYSQA
MAV_3110|M.avium_104 -------------------------------MSVIAGVFGALPPHRYPQR
MSMEG_0808|M.smegmatis_MC2_155 ---------------------MENTAFTPSGTCTIAGVHGVLPPHRYTQA
MAB_1141c|M.abscessus_ATCC_199 ----------------------------MTDIAEITGIN-KIGLLSLGAY
. * *:
MUL_1775|M.ulcerans_Agy99 DAAARVSELFVDPQQRERISRIYDKTRIDTRRMAVDPLDDEFDEFRREPA
MMAR_2190|M.marinum_M DAAARVSELFVDPQQRERISRIYDKTRIDTRRMAVDPLDDEFDEFRREPA
Mb1406|M.bovis_AF2122/97 DAADRVAELFLDPGQRERIPRVYQKSRITTRRMAVDPLDAKFDVFRREPA
Rv1372|M.tuberculosis_H37Rv DAADRVAELFLDPGQRERIPRVYQKSRITTRRMAVDPLDAKFDVFRREPA
Mflv_5140|M.gilvum_PYR-GCK EVTDAFLAAPAFAEVGDLLRSLHTNAKVDARHLVLP-----LEQYP-DLL
Mvan_1196|M.vanbaalenii_PYR-1 EITERFVAVPAFAELEDVVRGLHKHAKVDARHFVLP-----MDRYP-TLV
MAV_3110|M.avium_104 ELTDFFVSIPEFEGYEDIVRQLHASAKVGSRHLVLP-----LEQYP-TLT
MSMEG_0808|M.smegmatis_MC2_155 EVTEALLDLPGYADFEGIVRSLHKSAKVNSRYLTLP-----LEEYA-ALD
MAB_1141c|M.abscessus_ATCC_199 RPERVVTNDEICERIESSDEWIYTRTGIKTRRFAAD--------------
. :: : : :* :.
MUL_1775|M.ulcerans_Agy99 TIRDRMNLFYQHAVPLAVDVAARALDGLPYAPDEIGQLVFVTSTGFIAPG
MMAR_2190|M.marinum_M TIRDRMNLFYQHAVPLAVDVAARALDGLPYAPDEIGQLVFVTSTGFIAPG
Mb1406|M.bovis_AF2122/97 TIRDRMHLFYEHAVPLAVDVSKRALAGLPYRAAEIGLLVLATSTGFIAPG
Rv1372|M.tuberculosis_H37Rv TIRDRMHLFYEHAVPLAVDVSKRALAGLPYRAAEIGLLVLATSTGFIAPG
Mflv_5140|M.gilvum_PYR-GCK DFGDANDLYIHHAVELGCQALTAALDEAGLAPSDLDVIMSTTVTGIAVPS
Mvan_1196|M.vanbaalenii_PYR-1 DFGETNDLYLEHSLDLACEALTAALDEAGLGPRDLDMIMTTTVTGIAVPS
MAV_3110|M.avium_104 DFGVANRIFIDHAVTLGCAALSGALDEAGLKPEDLDVLITTTVTGLAVPS
MSMEG_0808|M.smegmatis_MC2_155 DFGETNGLFIEHATELGCAALTGALDEAGLRPEDVDLIITTTVTGAVVPS
MAB_1141c|M.abscessus_ATCC_199 ---------EETAQTLAIEAGRKAIANALLTGAEIDAVIVATSTHYLQTP
. : *. . *: ::. :: .* * .
MUL_1775|M.ulcerans_Agy99 VDVEIVKQLGLPRSISRVVVNFMGCAAAMNAIRTATNYVRAHPSMKALVV
MMAR_2190|M.marinum_M VDVEIVKQLGLPRSISRVVVNFMGCAAAMNAIRTATNYVRAHPSMKALVV
Mb1406|M.bovis_AF2122/97 VDVAIVKELGLSPSISRVVVNFMGCAAAMNALGTATNYVRAHPAMKALVV
Rv1372|M.tuberculosis_H37Rv VDVAIVKELGLSPSISRVVVNFMGCAAAMNALGTATNYVRAHPAMKALVV
Mflv_5140|M.gilvum_PYR-GCK LDARIAAKLGLRPDVRRVPLFGLGCVAGAAGIARMHDYLRGAPGHVAALI
Mvan_1196|M.vanbaalenii_PYR-1 LDARIADRLGLRPDVRRVPLFGLGCVAGAAGIARMHDYLRGAPDHIAALV
MAV_3110|M.avium_104 VDARIAARLGLRDDVRRVPLFGLGCVAGAAGVARMHDYLRGAPDAVAALV
MSMEG_0808|M.smegmatis_MC2_155 LDARIAGRVGLRPDVRRVPIFGLGCVAGAAGVARLNDYLRGAPDKVAVLV
MAB_1141c|M.abscessus_ATCC_199 ASAPAVATALGAQGVPAFDLS-AGCAGFGYAVGVAGDMIRGGSASKVLVI
.. . .: . : **.. .: : :*. . . ::
MUL_1775|M.ulcerans_Agy99 CIELSSVNA-VFADDINDVVIHSLFGDGCGALVIGASQAQQPLPAGNVVI
MMAR_2190|M.marinum_M CIELSSVNA-VFADDINDVVIHSLFGDGCGALVIGASQVQQPLPAGNVVI
Mb1406|M.bovis_AF2122/97 CIELCSVNA-VFADDINDVVIHSLFGDGCAALVIGASQVQEKLEPGKVVV
Rv1372|M.tuberculosis_H37Rv CIELCSVNA-VFADDINDVVIHSLFGDGCAALVIGASQVQEKLEPGKVVV
Mflv_5140|M.gilvum_PYR-GCK SVELCSLTRPALAPTIGSLVGSALFGDGAAAVVAVGEERAGHIRASGPDV
Mvan_1196|M.vanbaalenii_PYR-1 SVELCSLTYPAVEPTMASLVGSALFGDGAAAVIAVGAERAETIGATGPEV
MAV_3110|M.avium_104 SVELCSLTYPGYKPSLAGLVGSALFADGAGAVVAVGERRAEQLDAAGPSV
MSMEG_0808|M.smegmatis_MC2_155 SVELCSLTH-KHTPSMPTLVAGALFGDGASAVVAVGAGRAEQLDPIGPDV
MAB_1141c|M.abscessus_ATCC_199 GSEKLSPAL-----DMTDRGNCFIFGDGAGAVVVG-ETAEQGIGPTVWGS
* * : :*.**..*:: : .
MUL_1775|M.ulcerans_Agy99 RSSFSQLLDDSEDGIVLGVNHDG-----ITCELSENLPSYIYRSVDPVVA
MMAR_2190|M.marinum_M RSSFSQLLDDSEDGIVLGVNHDG-----ITCELSENLPSYIYRSVDPVVA
Mb1406|M.bovis_AF2122/97 RSSFSQLLDNTEDGIVLGVNHNG-----ITCELSENLPGYIFSGVAPVVT
Rv1372|M.tuberculosis_H37Rv RSSFSQLLDNTEDGIVLGVNHNG-----ITCELSENLPGYIFSGVAPVVT
Mflv_5140|M.gilvum_PYR-GCK LDSRSRMYPDSLDIMGWSVNHNG-----FQLVLSPELPALIERYLPDDMA
Mvan_1196|M.vanbaalenii_PYR-1 LDTRSRMYPDSLDTMGWRVGASG-----FQLILSPNLPELIERYLADDMA
MAV_3110|M.avium_104 LDSRSHLYPDSLRTMGYDVGATG-----FELVLSKDVAAVVEQYIEDDVT
MSMEG_0808|M.smegmatis_MC2_155 LDSRSHLYPDSLHAMGWDIGTKG-----FEIVLSAEVPGFVGRYLGDDVT
MAB_1141c|M.abscessus_ATCC_199 DGSQSNAIRQDIDWMDFAAAPDPEGPRPYLRIEGTSVFRWAAFEMGKVGQ
.: *. : : . .: :
MUL_1775|M.ulcerans_Agy99 EMLRDNGLSKADIDLWAIHPGGPKIIEQSARSLGIPVGRAVQSWDVLAQF
MMAR_2190|M.marinum_M EMLRDNGLSKADIDLWAIHPGGPKIIEQSARSLGIPVGRAVQSWDVLAQF
Mb1406|M.bovis_AF2122/97 EMLWDNGLQISDIDLWAIHPGGPKIIEQSVRSLGISAELAAQSWDVLARF
Rv1372|M.tuberculosis_H37Rv EMLWDNGLQISDIDLWAIHPGGPKIIEQSVRSLGISAELAAQSWDVLARF
Mflv_5140|M.gilvum_PYR-GCK SFLGEHDLGIGDIATWVSHPGGPKVLEAIASALDLPDDALELSWRSLAEI
Mvan_1196|M.vanbaalenii_PYR-1 GFLGAHDLQIGDIAAWVSHPGGPKVMEAISETLGLPDDALDLAWRSLAEV
MAV_3110|M.avium_104 GFLGAHGLTTNDIGAFVSHPGGPKVIEAINAALGLPPEALELTWRSLGEI
MSMEG_0808|M.smegmatis_MC2_155 EFLGEHGVATDDVSAWVSHPGGPKVIEAIIETLDLPSDALDLTWQSLAEV
MAB_1141c|M.abscessus_ATCC_199 RAMEAAKVGPEQIDVFVPHQANTRINELLAKNLHLRADAVIAN--DIEHT
: : :: :. * ...:: * * : : .
MUL_1775|M.ulcerans_Agy99 GNMLSVSLIFVLEMMVAQAESDKPISTGVAFAFAPGVTVEGMLFDIIRR-
MMAR_2190|M.marinum_M GNMLSVSLIFVLEMMVAQAESDKPISTGVAFAFAPGVTVEGMLFDIIRR-
Mb1406|M.bovis_AF2122/97 GNMLSVSLIFVLETMVQQAESAKAISTGVAFAFGPGVTVEGMLFDIIRR-
Rv1372|M.tuberculosis_H37Rv GNMLSVSLIFVLETMVQQAESAKAISTGVAFAFGPGVTVEGMLFDIIRR-
Mflv_5140|M.gilvum_PYR-GCK GNLSSSSVLHILRDTIAKKPPAA--TPGLLMAMGPGFCSELVLLRWH---
Mvan_1196|M.vanbaalenii_PYR-1 GNLSSSSVLHVLRDTRAKKPPAG--TPGLLMAMGPGFCSELVLLRWR---
MAV_3110|M.avium_104 GNLSSASVLHVLRDTLAKPPPSD--SPGLMLAMGPGFCSELVLLRWH---
MSMEG_0808|M.smegmatis_MC2_155 GNLSSSSVLHVLRDTIRKRPPAG--TPGVLMAMGPGFCSELVLLRWR---
MAB_1141c|M.abscessus_ATCC_199 GNTSAASVPLAMETLLSTG-AAKPGDLALLIGYGAGLSYAAQVVRMPPVP
** : *: :. . .: :. ..*. :.
MUL_1775|M.ulcerans_Agy99 --
MMAR_2190|M.marinum_M --
Mb1406|M.bovis_AF2122/97 --
Rv1372|M.tuberculosis_H37Rv --
Mflv_5140|M.gilvum_PYR-GCK --
Mvan_1196|M.vanbaalenii_PYR-1 --
MAV_3110|M.avium_104 --
MSMEG_0808|M.smegmatis_MC2_155 --
MAB_1141c|M.abscessus_ATCC_199 FE