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MSTAAEGGAIRRAGHEPRYDLAQLPPAPPTTVAVIEGMATGAPQRVVAQADAAARVSELFVDPQQRERIS RIYDKTRIDTRRMAVDPLDDEFDEFRREPATIRDRMNLFYQHAVPLAVDVAARALDGLPYAPDEIGQLVF VTSTGFIAPGVDVEIVKQLGLPRSISRVVVNFMGCAAAMNAIRTATNYVRAHPSMKALVVCIELSSVNAV FADDINDVVIHSLFGDGCGALVIGASQVQQPLPAGNVVIRSSFSQLLDDSEDGIVLGVNHDGITCELSEN LPSYIYRSVDPVVAEMLRDNGLSKADIDLWAIHPGGPKIIEQSARSLGIPVGRAVQSWDVLAQFGNMLSV SLIFVLEMMVAQAESDKPISTGVAFAFAPGVTVEGMLFDIIRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2190 | - | - | 100% (393) | chalcone/stilbene synthase |
| M. marinum M | MMAR_2474 | pks11_1 | 2e-32 | 26.46% (359) | chalcone synthase, Pks11_1 |
| M. marinum M | MMAR_2470 | pks10 | 2e-28 | 26.72% (363) | chalcone synthase, Pks10 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1406 | - | 1e-174 | 79.90% (393) | hypothetical protein Mb1406 |
| M. gilvum PYR-GCK | Mflv_5140 | - | 9e-37 | 29.44% (360) | chalcone/stilbene synthase domain-containing protein |
| M. tuberculosis H37Rv | Rv1372 | - | 1e-174 | 79.90% (393) | hypothetical protein Rv1372 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_3110 | - | 1e-30 | 30.85% (282) | Pks10 protein |
| M. smegmatis MC2 155 | MSMEG_0808 | - | 2e-34 | 27.55% (363) | chalcone synthase Pks10 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1775 | - | 0.0 | 99.49% (393) | chalcone/stilbene synthase |
| M. vanbaalenii PYR-1 | Mvan_1196 | - | 3e-32 | 27.02% (359) | chalcone/stilbene synthase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3110|M.avium_104 -------------------------------MSVIAGVFGALPPHRYPQR
MSMEG_0808|M.smegmatis_MC2_155 ---------------------MENTAFTPSGTCTIAGVHGVLPPHRYTQA
Mflv_5140|M.gilvum_PYR-GCK ------------------------MTDVHTPVSVIAGVQGALPPHRYSQA
Mvan_1196|M.vanbaalenii_PYR-1 ---------------------------MNDRISVIAGVQGALPPYRYSQA
MMAR_2190|M.marinum_M MSTAAEGGAIRRAGHEPRYDLAQLPPAPPTTVAVIEGMATGAPQRVVAQA
MUL_1775|M.ulcerans_Agy99 MSTAAEGGAICRAGHEPRYDLAQLPPAPPTTVAVIEGMATGAPQRVVAQA
Mb1406|M.bovis_AF2122/97 MNVSAESGAPRRAGQRHEVGLAQLPPAPPTTVAVIEGLATGTPRRVVNQS
Rv1372|M.tuberculosis_H37Rv MNVSAESGAPRRAGQRHEVGLAQLPPAPPTTVAVIEGLATGTPRRVVNQS
..* *: * *
MAV_3110|M.avium_104 ELTDFFVSIPEFEGYEDIVRQLHASAKVGSRHLVLP-----LEQYP-TLT
MSMEG_0808|M.smegmatis_MC2_155 EVTEALLDLPGYADFEGIVRSLHKSAKVNSRYLTLP-----LEEYA-ALD
Mflv_5140|M.gilvum_PYR-GCK EVTDAFLAAPAFAEVGDLLRSLHTNAKVDARHLVLP-----LEQYP-DLL
Mvan_1196|M.vanbaalenii_PYR-1 EITERFVAVPAFAELEDVVRGLHKHAKVDARHFVLP-----MDRYP-TLV
MMAR_2190|M.marinum_M DAAARVSELFVDPQQRERISRIYDKTRIDTRRMAVDPLDDEFDEFRREPA
MUL_1775|M.ulcerans_Agy99 DAAARVSELFVDPQQRERISRIYDKTRIDTRRMAVDPLDDEFDEFRREPA
Mb1406|M.bovis_AF2122/97 DAADRVAELFLDPGQRERIPRVYQKSRITTRRMAVDPLDAKFDVFRREPA
Rv1372|M.tuberculosis_H37Rv DAADRVAELFLDPGQRERIPRVYQKSRITTRRMAVDPLDAKFDVFRREPA
: : . : :: ::: :* :.: :: :
MAV_3110|M.avium_104 DFGVANRIFIDHAVTLGCAALSGALDEAGLKPEDLDVLITTTVTGLAVPS
MSMEG_0808|M.smegmatis_MC2_155 DFGETNGLFIEHATELGCAALTGALDEAGLRPEDVDLIITTTVTGAVVPS
Mflv_5140|M.gilvum_PYR-GCK DFGDANDLYIHHAVELGCQALTAALDEAGLAPSDLDVIMSTTVTGIAVPS
Mvan_1196|M.vanbaalenii_PYR-1 DFGETNDLYLEHSLDLACEALTAALDEAGLGPRDLDMIMTTTVTGIAVPS
MMAR_2190|M.marinum_M TIRDRMNLFYQHAVPLAVDVAARALDGLPYAPDEIGQLVFVTSTGFIAPG
MUL_1775|M.ulcerans_Agy99 TIRDRMNLFYQHAVPLAVDVAARALDGLPYAPDEIGQLVFVTSTGFIAPG
Mb1406|M.bovis_AF2122/97 TIRDRMHLFYEHAVPLAVDVSKRALAGLPYRAAEIGLLVLATSTGFIAPG
Rv1372|M.tuberculosis_H37Rv TIRDRMHLFYEHAVPLAVDVSKRALAGLPYRAAEIGLLVLATSTGFIAPG
: :: .*: *. . ** . ::. :: .* ** .*.
MAV_3110|M.avium_104 VDARIAARLGLRDDVRRVPLFGLGCVAGAAGVARMHDYLRGAPDAVAALV
MSMEG_0808|M.smegmatis_MC2_155 LDARIAGRVGLRPDVRRVPIFGLGCVAGAAGVARLNDYLRGAPDKVAVLV
Mflv_5140|M.gilvum_PYR-GCK LDARIAAKLGLRPDVRRVPLFGLGCVAGAAGIARMHDYLRGAPGHVAALI
Mvan_1196|M.vanbaalenii_PYR-1 LDARIADRLGLRPDVRRVPLFGLGCVAGAAGIARMHDYLRGAPDHIAALV
MMAR_2190|M.marinum_M VDVEIVKQLGLPRSISRVVVNFMGCAAAMNAIRTATNYVRAHPSMKALVV
MUL_1775|M.ulcerans_Agy99 VDVEIVKQLGLPRSISRVVVNFMGCAAAMNAIRTATNYVRAHPSMKALVV
Mb1406|M.bovis_AF2122/97 VDVAIVKELGLSPSISRVVVNFMGCAAAMNALGTATNYVRAHPAMKALVV
Rv1372|M.tuberculosis_H37Rv VDVAIVKELGLSPSISRVVVNFMGCAAAMNALGTATNYVRAHPAMKALVV
:*. *. .:** .: ** : :**.*. .: :*:*. * * ::
MAV_3110|M.avium_104 SVELCSLTYPGYKPSLAGLVGSALFADGAGAVVAVGERRAEQLDAAGPSV
MSMEG_0808|M.smegmatis_MC2_155 SVELCSLTHK-HTPSMPTLVAGALFGDGASAVVAVGAGRAEQLDPIGPDV
Mflv_5140|M.gilvum_PYR-GCK SVELCSLTRPALAPTIGSLVGSALFGDGAAAVVAVGEERAGHIRASGPDV
Mvan_1196|M.vanbaalenii_PYR-1 SVELCSLTYPAVEPTMASLVGSALFGDGAAAVIAVGAERAETIGATGPEV
MMAR_2190|M.marinum_M CIELSS-VNAVFADDINDVVIHSLFGDGCGALVIGASQVQQPLPAGNVVI
MUL_1775|M.ulcerans_Agy99 CIELSS-VNAVFADDINDVVIHSLFGDGCGALVIGASQAQQPLPAGNVVI
Mb1406|M.bovis_AF2122/97 CIELCS-VNAVFADDINDVVIHSLFGDGCAALVIGASQVQEKLEPGKVVV
Rv1372|M.tuberculosis_H37Rv CIELCS-VNAVFADDINDVVIHSLFGDGCAALVIGASQVQEKLEPGKVVV
.:**.* . : :* :**.**..*:: . : . :
MAV_3110|M.avium_104 LDSRSHLYPDSLRTMGYDVGATGFELVLSKDVAAVVEQYIEDDVTGFLGA
MSMEG_0808|M.smegmatis_MC2_155 LDSRSHLYPDSLHAMGWDIGTKGFEIVLSAEVPGFVGRYLGDDVTEFLGE
Mflv_5140|M.gilvum_PYR-GCK LDSRSRMYPDSLDIMGWSVNHNGFQLVLSPELPALIERYLPDDMASFLGE
Mvan_1196|M.vanbaalenii_PYR-1 LDTRSRMYPDSLDTMGWRVGASGFQLILSPNLPELIERYLADDMAGFLGA
MMAR_2190|M.marinum_M RSSFSQLLDDSEDGIVLGVNHDGITCELSENLPSYIYRSVDPVVAEMLRD
MUL_1775|M.ulcerans_Agy99 RSSFSQLLDDSEDGIVLGVNHDGITCELSENLPSYIYRSVDPVVAEMLRD
Mb1406|M.bovis_AF2122/97 RSSFSQLLDNTEDGIVLGVNHNGITCELSENLPGYIFSGVAPVVTEMLWD
Rv1372|M.tuberculosis_H37Rv RSSFSQLLDNTEDGIVLGVNHNGITCELSENLPGYIFSGVAPVVTEMLWD
.: *:: :: : :. *: ** ::. : : :: :*
MAV_3110|M.avium_104 HGLTTNDIGAFVSHPGGPKVIEAINAALGLPPEALELTWRSLGEIGNLSS
MSMEG_0808|M.smegmatis_MC2_155 HGVATDDVSAWVSHPGGPKVIEAIIETLDLPSDALDLTWQSLAEVGNLSS
Mflv_5140|M.gilvum_PYR-GCK HDLGIGDIATWVSHPGGPKVLEAIASALDLPDDALELSWRSLAEIGNLSS
Mvan_1196|M.vanbaalenii_PYR-1 HDLQIGDIAAWVSHPGGPKVMEAISETLGLPDDALDLAWRSLAEVGNLSS
MMAR_2190|M.marinum_M NGLSKADIDLWAIHPGGPKIIEQSARSLGIPVGRAVQSWDVLAQFGNMLS
MUL_1775|M.ulcerans_Agy99 NGLSKADIDLWAIHPGGPKIIEQSARSLGIPVGRAVQSWDVLAQFGNMLS
Mb1406|M.bovis_AF2122/97 NGLQISDIDLWAIHPGGPKIIEQSVRSLGISAELAAQSWDVLARFGNMLS
Rv1372|M.tuberculosis_H37Rv NGLQISDIDLWAIHPGGPKIIEQSVRSLGISAELAAQSWDVLARFGNMLS
:.: *: :. ******::* :*.:. :* *...**: *
MAV_3110|M.avium_104 ASVLHVLRDTLAKPPPSD--SPGLMLAMGPGFCSELVLLRWH--
MSMEG_0808|M.smegmatis_MC2_155 SSVLHVLRDTIRKRPPAG--TPGVLMAMGPGFCSELVLLRWR--
Mflv_5140|M.gilvum_PYR-GCK SSVLHILRDTIAKKPPAA--TPGLLMAMGPGFCSELVLLRWH--
Mvan_1196|M.vanbaalenii_PYR-1 SSVLHVLRDTRAKKPPAG--TPGLLMAMGPGFCSELVLLRWR--
MMAR_2190|M.marinum_M VSLIFVLEMMVAQAESDKPISTGVAFAFAPGVTVEGMLFDIIRR
MUL_1775|M.ulcerans_Agy99 VSLIFVLEMMVAQAESDKPISTGVAFAFAPGVTVEGMLFDIIRR
Mb1406|M.bovis_AF2122/97 VSLIFVLETMVQQAESAKAISTGVAFAFGPGVTVEGMLFDIIRR
Rv1372|M.tuberculosis_H37Rv VSLIFVLETMVQQAESAKAISTGVAFAFGPGVTVEGMLFDIIRR
*::.:*. : . :.*: :*:.**. * :*: