For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTDVHTPVSVIAGVQGALPPHRYSQAEVTDAFLAAPAFAEVGDLLRSLHTNAKVDARHLVLPLEQYPDLL DFGDANDLYIHHAVELGCQALTAALDEAGLAPSDLDVIMSTTVTGIAVPSLDARIAAKLGLRPDVRRVPL FGLGCVAGAAGIARMHDYLRGAPGHVAALISVELCSLTRPALAPTIGSLVGSALFGDGAAAVVAVGEERA GHIRASGPDVLDSRSRMYPDSLDIMGWSVNHNGFQLVLSPELPALIERYLPDDMASFLGEHDLGIGDIAT WVSHPGGPKVLEAIASALDLPDDALELSWRSLAEIGNLSSSSVLHILRDTIAKKPPAATPGLLMAMGPGF CSELVLLRWH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5140 | - | - | 100% (360) | chalcone/stilbene synthase domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3991 | - | 6e-96 | 51.68% (358) | chalcone/stilbene synthase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1693 | pks11 | 1e-141 | 67.90% (352) | chalcone synthase |
| M. tuberculosis H37Rv | Rv1665 | pks11 | 1e-141 | 67.90% (352) | chalcone synthase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1141c | - | 1e-05 | 27.78% (288) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. marinum M | MMAR_2474 | pks11_1 | 1e-147 | 70.54% (353) | chalcone synthase, Pks11_1 |
| M. avium 104 | MAV_3110 | - | 1e-141 | 69.12% (353) | Pks10 protein |
| M. smegmatis MC2 155 | MSMEG_0808 | - | 1e-137 | 67.05% (349) | chalcone synthase Pks10 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1656 | pks11 | 1e-146 | 69.97% (353) | chalcone synthase, Pks11 |
| M. vanbaalenii PYR-1 | Mvan_1196 | - | 1e-164 | 78.69% (352) | chalcone/stilbene synthase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5140|M.gilvum_PYR-GCK ---MTDVHTPVSVIAGVQGALPPHRYSQAEVTDAFLAAPAFAEVGDLLRS
Mvan_1196|M.vanbaalenii_PYR-1 ------MNDRISVIAGVQGALPPYRYSQAEITERFVAVPAFAELEDVVRG
Mb1693|M.bovis_AF2122/97 ----------MSVIAGVFGALPPHRYSQSEITDSFVEFPGLKEHEEIIRR
Rv1665|M.tuberculosis_H37Rv ----------MSVIAGVFGALPPHRYSQSEITDSFVEFPGLKEHEEIIRR
MMAR_2474|M.marinum_M ----------MSVIAGVFGALPPHRYSQSEITEAFLEFPGLQEHEEIVRR
MUL_1656|M.ulcerans_Agy99 ----------MSVIAGVFGALPPHRYSQSEITESFLEFPGLQEHEEIVRR
MAV_3110|M.avium_104 ----------MSVIAGVFGALPPHRYPQRELTDFFVSIPEFEGYEDIVRQ
MSMEG_0808|M.smegmatis_MC2_155 MENTAFTPSGTCTIAGVHGVLPPHRYTQAEVTEALLDLPGYADFEGIVRS
MAB_1141c|M.abscessus_ATCC_199 ----------MTDIAEITGIN----------KIGLLSLGAYRP-ERVVTN
** : * . :: ::
Mflv_5140|M.gilvum_PYR-GCK LHTNAKVDARHLVLPLEQYPDLLDFGDANDLYIHHAVELGCQALTAALDE
Mvan_1196|M.vanbaalenii_PYR-1 LHKHAKVDARHFVLPMDRYPTLVDFGETNDLYLEHSLDLACEALTAALDE
Mb1693|M.bovis_AF2122/97 LHAAAKVNGRHLVLPLQQYPSLTDFGDANEIFIEKAVDLGVEALLGALDD
Rv1665|M.tuberculosis_H37Rv LHAAAKVNGRHLVLPLQQYPSLTDFGDANEIFIEKAVDLGVEALLGALDD
MMAR_2474|M.marinum_M MHAAAKVNSRQFVLPIEQYPALTDFGDANEIFIEKAVDLGIEALMGALDE
MUL_1656|M.ulcerans_Agy99 MHAAAKVNSRQFVLPIEQYPALTDFGDTNEIFIEKAVDLGIEALMGALDE
MAV_3110|M.avium_104 LHASAKVGSRHLVLPLEQYPTLTDFGVANRIFIDHAVTLGCAALSGALDE
MSMEG_0808|M.smegmatis_MC2_155 LHKSAKVNSRYLTLPLEEYAALDDFGETNGLFIEHATELGCAALTGALDE
MAB_1141c|M.abscessus_ATCC_199 DEICERIESSDEWIYTRTGIKTRRFAADEETAQTLAIEAGRKAIANALLT
. :: . : *. : : . *: **
Mflv_5140|M.gilvum_PYR-GCK AGLAPSDLDVIMSTTVTGIAVPSLDARIAAKLGLRPDVRRVPLFGL--GC
Mvan_1196|M.vanbaalenii_PYR-1 AGLGPRDLDMIMTTTVTGIAVPSLDARIADRLGLRPDVRRVPLFGL--GC
Mb1693|M.bovis_AF2122/97 ANLRPSDIDMIATATVTGVAVPSLDARIAGRLGLRPDVRRMPLFGL--GC
Rv1665|M.tuberculosis_H37Rv ANLRPSDIDMIATATVTGVAVPSLDARIAGRLGLRPDVRRMPLFGL--GC
MMAR_2474|M.marinum_M AGLTPQDIDLIITTTVTGVAVPSLDARIAGRLGLRPDVRRMPLFGL--GC
MUL_1656|M.ulcerans_Agy99 AGLTPQDIDLIITTTVTGVAVPSLDARIAGRLGLRPDVRRMPLFGL--GC
MAV_3110|M.avium_104 AGLKPEDLDVLITTTVTGLAVPSVDARIAARLGLRDDVRRVPLFGL--GC
MSMEG_0808|M.smegmatis_MC2_155 AGLRPEDVDLIITTTVTGAVVPSLDARIAGRVGLRPDVRRVPIFGL--GC
MAB_1141c|M.abscessus_ATCC_199 G---AEIDAVIVATSTHYLQTPASAPAVATALGAQG----VPAFDLSAGC
. . :: :::. .*: . :* :* : :* *.* **
Mflv_5140|M.gilvum_PYR-GCK VAGAAGIARMHDYLRGAPGHVAALISVELCSLTRPALAPTIGSLVGSALF
Mvan_1196|M.vanbaalenii_PYR-1 VAGAAGIARMHDYLRGAPDHIAALVSVELCSLTYPAVEPTMASLVGSALF
Mb1693|M.bovis_AF2122/97 VAGAAGVARLRDYLRGAPDDVAVLVSVELCSLTYPAVKPTVSSLVGTALF
Rv1665|M.tuberculosis_H37Rv VAGAAGVARLRDYLRGAPDDVAVLVSVELCSLTYPAVKPTVSSLVGTALF
MMAR_2474|M.marinum_M VAGAAGVARLHDYLRGAPDGVAVLIAVELCSLTYPAVKPTVSGIVGTALF
MUL_1656|M.ulcerans_Agy99 VAGAAGVARLHDYLRGAPDGVAVLIAVELCSLTYPAVKPTVSGIVGTALF
MAV_3110|M.avium_104 VAGAAGVARMHDYLRGAPDAVAALVSVELCSLTYPGYKPSLAGLVGSALF
MSMEG_0808|M.smegmatis_MC2_155 VAGAAGVARLNDYLRGAPDKVAVLVSVELCSLTH-KHTPSMPTLVAGALF
MAB_1141c|M.abscessus_ATCC_199 AGFGYAVGVAGDMIRGGSASKVLVIGSEKLSPALDMTDRGN-----CFIF
.. . .:. * :**.. . ::. * * : :*
Mflv_5140|M.gilvum_PYR-GCK GDGAAAVVAVGEERAGHIRASGPDVLDSRSRMYPDSLDIMGWSVN-----
Mvan_1196|M.vanbaalenii_PYR-1 GDGAAAVIAVGAERAETIGATGPEVLDTRSRMYPDSLDTMGWRVG-----
Mb1693|M.bovis_AF2122/97 GDGAAAVVAVGDRRAEQVRAGGPDILDSRSSLYPDSLHIMGWDVG-----
Rv1665|M.tuberculosis_H37Rv GDGAAAVVAVGDRRAEQVRAGGPDILDSRSSLYPDSLHIMGWDVG-----
MMAR_2474|M.marinum_M GDGAAAVVAVGDRRAEQIRAGGPDILDSRSRLYPESLDIMGWDVG-----
MUL_1656|M.ulcerans_Agy99 GDGAAAVVAVGDRRAEQIRAGGPDILDSRSRLYPESLDIMGWDVG-----
MAV_3110|M.avium_104 ADGAGAVVAVGERRAEQLDAAGPSVLDSRSHLYPDSLRTMGYDVG-----
MSMEG_0808|M.smegmatis_MC2_155 GDGASAVVAVGAGRAEQLDPIGPDVLDSRSHLYPDSLHAMGWDIG-----
MAB_1141c|M.abscessus_ATCC_199 GDGAG-AVVVGETAEQGIGPTVWGSDGSQSNAIRQDIDWMDFAAAPDPEG
.***. .:.** : . .::* :.: *.:
Mflv_5140|M.gilvum_PYR-GCK HNGFQLVLSPELPALIERYLPDDMASFLGEHDLGIGDIATWVSHPGGPKV
Mvan_1196|M.vanbaalenii_PYR-1 ASGFQLILSPNLPELIERYLADDMAGFLGAHDLQIGDIAAWVSHPGGPKV
Mb1693|M.bovis_AF2122/97 SHGLRLRLSPDLTNLIERYLANDVTTFLDAHRLTKDDIGAWVSHPGGPKV
Rv1665|M.tuberculosis_H37Rv SHGLRLRLSPDLTNLIERYLANDVTTFLDAHRLTKDDIGAWVSHPGGPKV
MMAR_2474|M.marinum_M SHGLQLRLAPELTNLIEEYLPDDVDAFLAMHDLTKNDIGAWVSHPGGPKV
MUL_1656|M.ulcerans_Agy99 SHGLQLRLAPELTNLIEEYLPDDVDAFLAMHDLTKNDIGAWVSHPGGPKV
MAV_3110|M.avium_104 ATGFELVLSKDVAAVVEQYIEDDVTGFLGAHGLTTNDIGAFVSHPGGPKV
MSMEG_0808|M.smegmatis_MC2_155 TKGFEIVLSAEVPGFVGRYLGDDVTEFLGEHGVATDDVSAWVSHPGGPKV
MAB_1141c|M.abscessus_ATCC_199 PRPYLRIEGTSVFRWAAFEMGKVGQRAMEAAKVGPEQIDVFVPHQANTRI
. .: : . : : :: .:*.* ...::
Mflv_5140|M.gilvum_PYR-GCK LEAIASALDLPDDALELSWRSLAEIGNLSSSSVLHILRDTIAK-KPPAAT
Mvan_1196|M.vanbaalenii_PYR-1 MEAISETLGLPDDALDLAWRSLAEVGNLSSSSVLHVLRDTRAK-KPPAGT
Mb1693|M.bovis_AF2122/97 IDAVATSLALPPEALELTWRSLGEIGNLSSASILHILRDTIEK-RPPSGS
Rv1665|M.tuberculosis_H37Rv IDAVATSLALPPEALELTWRSLGEIGNLSSASILHILRDTIEK-RPPSGS
MMAR_2474|M.marinum_M LDAITNSLGLPSDALELTWRSLGEIGNLSSASVLHILRDTIAK-VPPSGS
MUL_1656|M.ulcerans_Agy99 LDAIANSLGLPSDALELTWRSLGEIGNLSSASVLRILRDTIAK-VPPSGS
MAV_3110|M.avium_104 IEAINAALGLPPEALELTWRSLGEIGNLSSASVLHVLRDTLAK-PPPSDS
MSMEG_0808|M.smegmatis_MC2_155 IEAIIETLDLPSDALDLTWQSLAEVGNLSSSSVLHVLRDTIRK-RPPAGT
MAB_1141c|M.abscessus_ATCC_199 NELLAKNLHLRADAVIAN--DIEHTGNTSAASVPLAMETLLSTGAAKPGD
: : * * :*: .: . ** *::*: :. . . .
Mflv_5140|M.gilvum_PYR-GCK PGLLMAMGPGFCSELVLLRWH-----
Mvan_1196|M.vanbaalenii_PYR-1 PGLLMAMGPGFCSELVLLRWR-----
Mb1693|M.bovis_AF2122/97 AGLMLAMGPGFCTELVLLRWR-----
Rv1665|M.tuberculosis_H37Rv AGLMLAMGPGFCTELVLLRWR-----
MMAR_2474|M.marinum_M PGLMLAMGPGFCAELVLLRWH-----
MUL_1656|M.ulcerans_Agy99 PGLMLAMGPGFCAELVLLRWH-----
MAV_3110|M.avium_104 PGLMLAMGPGFCSELVLLRWH-----
MSMEG_0808|M.smegmatis_MC2_155 PGVLMAMGPGFCSELVLLRWR-----
MAB_1141c|M.abscessus_ATCC_199 LALLIGYGAGLSYAAQVVRMPPVPFE
.:::. *.*:. ::*