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MSGPLNGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSSAGGRGGGVKDAMLRNRRIVTADLKSDQG RELVLKLVAKADVLIEGYRPGVTERLGLGPQDCAKVNDRLIYARMTGWGQAGPRSQQAGHDINYISLNGI LHAIGRVGERPVPPLNLVGDFGGGSMFLLVGILAALWERHNSGKGQVIDAAMVDGSSVLVQMMWAMRGIG IWSDVRGTNMLDGGAPYYDTYECADGGYVAVGAIEPQFYAAMLAGLGLDAVNLPPQNDVARWPELRAVLT EAFGRYDRDHWAKVFADSDACVTPVLSFGEVHTEPHIAERNTFYEGDDGGPQPMPAPRFSRTVPSRPRPP AAPLTDVEAVLSDWA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0986 | mcr | - | 100% (365) | alpha-methylacyl-CoA racemase Mcr |
| M. ulcerans Agy99 | MUL_2446 | - | 2e-32 | 33.83% (266) | hypothetical protein MUL_2446 |
| M. ulcerans Agy99 | MUL_2621 | - | 6e-27 | 28.09% (356) | acyl-CoA transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1175 | mcr | 1e-180 | 84.89% (364) | alpha-methylacyl-CoA racemase |
| M. gilvum PYR-GCK | Mflv_2126 | - | 1e-158 | 71.98% (364) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv1143 | mcr | 1e-180 | 84.89% (364) | alpha-methylacyl-CoA racemase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0845 | - | 1e-106 | 55.49% (346) | fatty-acid-CoA racemase Far |
| M. marinum M | MMAR_4308 | mcr | 0.0 | 100.00% (364) | alpha-methylacyl-CoA racemase Mcr |
| M. avium 104 | MAV_1284 | - | 0.0 | 85.44% (364) | Mcr protein |
| M. smegmatis MC2 155 | MSMEG_5184 | - | 1e-162 | 75.34% (369) | alpha-methylacyl-CoA racemase, putative |
| M. thermoresistible (build 8) | TH_4477 | - | 1e-159 | 75.14% (366) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. vanbaalenii PYR-1 | Mvan_4578 | - | 1e-161 | 74.73% (364) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0986|M.ulcerans_Agy99 ------MSGPLNGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSSAG
MMAR_4308|M.marinum_M ------MSGPLNGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSSAG
MAV_1284|M.avium_104 ------MAGPLQGLRVVELSGIGPGPHAAMILGDLGADVVRIDRPS---G
Mb1175|M.bovis_AF2122/97 ------MAGPLSGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPS----
Rv1143|M.tuberculosis_H37Rv ------MAGPLSGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPS----
Mflv_2126|M.gilvum_PYR-GCK ------MAGPLQGLRVVELAGIGPGPHAAMIFGDLGADVVRIERPGKGPG
Mvan_4578|M.vanbaalenii_PYR-1 ------MAGPLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPGKGPG
TH_4477|M.thermoresistible__bu ------MAGPLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPRNTPG
MSMEG_5184|M.smegmatis_MC2_155 ------MAGPLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPGKGGG
MAB_0845|M.abscessus_ATCC_1997 MADTGVKTGPLAGVKVIELGGIGPGPHAAMMLSDLGADVIRVRRPG---G
:*** *::*:**.**********::.******:*: **
MUL_0986|M.ulcerans_Agy99 -GRGGGVKDAMLRNRRIVTADLKSDQGRELVLKLVAKADVLIEGYRPGVT
MMAR_4308|M.marinum_M -GRGGGVKDAMLRNRRIVTADLKSDQGRELVLKLVAKADVLIEGYRPGVT
MAV_1284|M.avium_104 -APGGVVKDAMSRNRRIVTADLKSDQGRELVLKLVAKADVLIEGYRPGVT
Mb1175|M.bovis_AF2122/97 -SVDGISRDAMLRNRRIVTADLKSDQGLELALKLIAKADVLIEGYRPGVT
Rv1143|M.tuberculosis_H37Rv -SVDGISRDAMLRNRRIVTADLKSDQGLELALKLIAKADVLIEGYRPGVT
Mflv_2126|M.gilvum_PYR-GCK PATKPGG-DYLLRNRRSVAANLKSDEDREMVLRLIAKADVLIEGFRPGVT
Mvan_4578|M.vanbaalenii_PYR-1 PATKPGG-DYLLRNRRSVAANLKSEEDRDMVLRLIAKADVLIEGFRPGVT
TH_4477|M.thermoresistible__bu PGIPRGAKDHLLRNRRSVAADLKTEEGKELVRKLIAKADVLIEGYRPGVT
MSMEG_5184|M.smegmatis_MC2_155 --VPAGDRDAMLRNRRSVVADLKAPEGRDLVLQLVAKADVLIEGYRPGVT
MAB_0845|M.abscessus_ATCC_1997 LAIPAEETDLFHRGKRLVNLDVKKDP--EALLALVDKADVLLDPFRPGVC
* : *.:* * ::* : *: *****:: :****
MUL_0986|M.ulcerans_Agy99 ERLGLGPQDCAKVNDRLIYARMTGWGQAGPRSQQAGHDINYISLNGILHA
MMAR_4308|M.marinum_M ERLGLGPQDCAKVNDRLIYARMTGWGQAGPRSQQAGHDINYISLNGILHA
MAV_1284|M.avium_104 ERLGLGPQDCAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHA
Mb1175|M.bovis_AF2122/97 ERLGLGPEECAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHA
Rv1143|M.tuberculosis_H37Rv ERLGLGPEECAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHA
Mflv_2126|M.gilvum_PYR-GCK ERLGLGPEDCAKVNEKLVYARMTGWGQDGPRAQQAGHDINYISLNGVLHA
Mvan_4578|M.vanbaalenii_PYR-1 ERLGLGPHDCAKVNEKLIYARMTGWGQDGPRAQQAGHDINYISLNGALHA
TH_4477|M.thermoresistible__bu ERLGLGPEDCAKINPRLIYGRMTGWGQDGPRAQQAGHDINYISLNGTLHA
MSMEG_5184|M.smegmatis_MC2_155 ERLGLGPEDCAKVNERLIYARMTGWGQDGPRALQAGHDINYISLNGTLHA
MAB_0845|M.abscessus_ATCC_1997 ERIGIGPEECAKRNPRLIFARMTGWGQHGPMADRAGHDINYLSLTGALGS
**:*:**.:*** * :*::.******* ** : :*******:**.* * :
MUL_0986|M.ulcerans_Agy99 IGRVGERPVPPLNLVGDFGGGSMFLLVGILAALWERHNSGKGQVIDAAMV
MMAR_4308|M.marinum_M IGRVGERPVPPLNLVGDFGGGSMFLLVGILAALWERHNSGKGQVIDAAMV
MAV_1284|M.avium_104 IGRANERPVPPLNLVGDFGGGSMFLLLGILSALWERQSSGKGQVVDAAMV
Mb1175|M.bovis_AF2122/97 IGRGDERPVPPLNLVGDFGGGSMFLLVGILAALWERQSSGKGQVVDAAMV
Rv1143|M.tuberculosis_H37Rv IGRGDERPVPPLNLVGDFGGGSMFLLVGILAALWERQSSGKGQVVDAAMV
Mflv_2126|M.gilvum_PYR-GCK IGRHGERPVPPLNLAGDFGGGSMFLLVGVLAALWERERSGKGQVVDAAMV
Mvan_4578|M.vanbaalenii_PYR-1 IGRAGERPVPPLNLVGDFGGGSMFLLVGVLSALYERERSGKGQVVDAAMV
TH_4477|M.thermoresistible__bu VGRKGERPVPPLNLAGDFGGGSMFLLVGILAALFERQTSGKGQVVDAAMI
MSMEG_5184|M.smegmatis_MC2_155 VGRKGGRPVPPLNLAGDFGGGSMFLLVGILSALYERQASGKGQVIDAAMV
MAB_0845|M.abscessus_ATCC_1997 MGYKDRPPMPPMNLVADFGGGSMLLVQGILAALYEREKSGKGQVIDGAMV
:* . *:**:**..*******:*: *:*:**:**. ******:*.**:
MUL_0986|M.ulcerans_Agy99 DGSSVLVQMMWAMRGIGIWSDVRGTNMLDGGAPYYDTYECADGGYVAVGA
MMAR_4308|M.marinum_M DGSSVLVQMMWAMRGIGIWSDVRGTNMLDGGAPYYDTYECADGGYVAVGA
MAV_1284|M.avium_104 DGSSVLVQMMWQMRASGMWTDARGTNLLDGGAPYYDTYECADGRYVAVGA
Mb1175|M.bovis_AF2122/97 DGSSVLIQMMWAMRATGMWTDTRGANMLDGGAPYYDTYECADGRYVAVGA
Rv1143|M.tuberculosis_H37Rv DGSSVLIQMMWAMRATGMWTDTRGANMLDGGAPYYDTYECADGRYVAVGA
Mflv_2126|M.gilvum_PYR-GCK DGSSVLSMMMWSFRGMGMWSDERGVNMLDTGAPYYDTYECSDGRHIAVGC
Mvan_4578|M.vanbaalenii_PYR-1 DGSSVLSMMMWAFRGMGMWSDERGTNMLDTGAPYYDTYETADGKYVAVGA
TH_4477|M.thermoresistible__bu DGSAVLMQMMWAFRAMGMWSDERGVNMLDTGAPYYDTYETADGKYVAVGA
MSMEG_5184|M.smegmatis_MC2_155 DGSAVLMEMMWSFRANGMWSDERGTNMLDTGAPYYDTYETADGKYIAVGA
MAB_0845|M.abscessus_ATCC_1997 DGVSQLAQMQWTMYNNGLLFDEREAGLLDGGSPFYGTYETSDGKYMAVGS
** : * * * : *: * * ..:** *:*:*.*** :** ::***.
MUL_0986|M.ulcerans_Agy99 IEPQFYAAMLAGLGLDAVNLPPQNDVARWPELRAVLTEAFGRYDRDHWAK
MMAR_4308|M.marinum_M IEPQFYAAMLAGLGLDAVNLPPQNDVARWPELRAVLTEAFGRYDRDHWAK
MAV_1284|M.avium_104 IEPQFYAAMLAGLGLDGADLPGQNDVSRWPELRAALTEKFASRDRDHWAK
Mb1175|M.bovis_AF2122/97 IEPQFYAAMLAGLGLDAAELPPQNDRARWPELRALLTEAFASHDRDHWGA
Rv1143|M.tuberculosis_H37Rv IEPQFYAAMLAGLGLDAAELPPQNDRARWPELRALLTEAFASHDRDHWGA
Mflv_2126|M.gilvum_PYR-GCK IEPQFYAEFLKGVGLEGADLPGQNDMGRWPELREAFSKAIAAHDRDHWAG
Mvan_4578|M.vanbaalenii_PYR-1 IEPQFYAEMLKGIGLDGADLPDQNDMSRWPELREAFTKAFAAHDRDHWAK
TH_4477|M.thermoresistible__bu IEPQFYAEMLKGLGLEGEDLPDQNDMSRWDELRARFAEVFKSKDRDHWAQ
MSMEG_5184|M.smegmatis_MC2_155 IEPQFYAELLKGLGLDGADLPAQNDISRWPELREAFAKAFAAHDRAHWTK
MAB_0845|M.abscessus_ATCC_1997 IEPQFFAILVQGLGLDPESVPFQLDKARYPEMRKMFDDAFKTKTRDEWTE
*****:* :: *:**: .:* * * .*: *:* : . : * .*
MUL_0986|M.ulcerans_Agy99 VFADSDACVTPVLSFGEVHTEPHIAERNTFYEGDDGGPQPMPAPRFSRTV
MMAR_4308|M.marinum_M VFADSDACVTPVLSFGEVHTEPHIAERNTFYEGDDGGPQPMPAPRFSRTV
MAV_1284|M.avium_104 VFADSDACVTPVLAFGEVQTEPHITERNTFYEVD-GGLQPLPAPRFSRTA
Mb1175|M.bovis_AF2122/97 VFANSDACVTPVLAFGEVHNEPHIIERNTFYEAN-GGWQPMPAPRFSRTA
Rv1143|M.tuberculosis_H37Rv VFANSDACVTPVLAFGEVHNEPHIIERNTFYEAN-GGWQPMPAPRFSRTA
Mflv_2126|M.gilvum_PYR-GCK VFAGTDACVTPVLSFAEVESEPHNTERDTFYSEN-GSLYPAPAPRFSRSV
Mvan_4578|M.vanbaalenii_PYR-1 VFAGTDACVTPVLSFAEVESEPHNTERDTFYSEN-GSLYPAPAPRFSRSA
TH_4477|M.thermoresistible__bu VFAGTDACVTPVLSFAEVESEAHVVERNTFYREG-DHLLPAPAPRFSRSV
MSMEG_5184|M.smegmatis_MC2_155 VFEGTDACTTPVLSFAEVLDEPHVAERNTFYDDE-GNLQPMPAPRFSRTQ
MAB_0845|M.abscessus_ATCC_1997 IFIGTDACVSPVLTWGEAKQNEHLRDRGTIVDVD-GVTQAAPAPRFSRTP
:* .:***.:***::.*. : * :*.*: . . *******:
MUL_0986|M.ulcerans_Agy99 PSRPRPPAAPLTDVEAVLSDWA-
MMAR_4308|M.marinum_M PSRPRPPAAPLTDVEAVLSDWV-
MAV_1284|M.avium_104 PETPR-PAAPVTDATAILDEWV-
Mb1175|M.bovis_AF2122/97 SSQPRPPAATI-DIEAVLTDWDG
Rv1143|M.tuberculosis_H37Rv SSQPRPPAATI-DIEAVLTDWDG
Mflv_2126|M.gilvum_PYR-GCK PSAPKAPGVPGADTEAVLQEWV-
Mvan_4578|M.vanbaalenii_PYR-1 PSAPKPPGVPGADTEAVLREWV-
TH_4477|M.thermoresistible__bu PSAPTPPRDPGADTDAVLQDWQ-
MSMEG_5184|M.smegmatis_MC2_155 PGRPTPPPQRGADTEAVLRDWS-
MAB_0845|M.abscessus_ATCC_1997 SGPLGAPPKDTTELSDIG--W--
. * : : *