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AGPLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPGKGGGVPAGDRDAMLRNRRSVVADLKAPEGRD LVLQLVAKADVLIEGYRPGVTERLGLGPEDCAKVNERLIYARMTGWGQDGPRALQAGHDINYISLNGTLH AVGRKGGRPVPPLNLAGDFGGGSMFLLVGILSALYERQASGKGQVIDAAMVDGSAVLMEMMWSFRANGMW SDERGTNMLDTGAPYYDTYETADGKYIAVGAIEPQFYAELLKGLGLDGADLPAQNDISRWPELREAFAKA FAAHDRAHWTKVFEGTDACTTPVLSFAEVLDEPHVAERNTFYDDEGNLQPMPAPRFSRTQPGRPTPPPQR GADTEAVLRDWS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5184 | - | - | 100% (363) | alpha-methylacyl-CoA racemase, putative |
| M. smegmatis MC2 155 | MSMEG_5734 | - | e-115 | 57.30% (356) | alpha-methylacyl-CoA racemase |
| M. smegmatis MC2 155 | MSMEG_4111 | - | 3e-49 | 32.51% (323) | alpha-methylacyl-CoA racemase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1175 | mcr | 1e-159 | 74.31% (362) | alpha-methylacyl-CoA racemase |
| M. gilvum PYR-GCK | Mflv_2126 | - | 1e-168 | 77.81% (365) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv1143 | mcr | 1e-159 | 74.31% (362) | alpha-methylacyl-CoA racemase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0845 | - | 1e-111 | 56.32% (348) | fatty-acid-CoA racemase Far |
| M. marinum M | MMAR_4308 | mcr | 1e-162 | 75.54% (368) | alpha-methylacyl-CoA racemase Mcr |
| M. avium 104 | MAV_1284 | - | 1e-161 | 75.21% (363) | Mcr protein |
| M. thermoresistible (build 8) | TH_4477 | - | 1e-173 | 80.22% (364) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_0986 | mcr | 1e-162 | 75.34% (369) | alpha-methylacyl-CoA racemase Mcr |
| M. vanbaalenii PYR-1 | Mvan_4578 | - | 1e-176 | 81.64% (365) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1175|M.bovis_AF2122/97 ------MAGPLSGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPS----
Rv1143|M.tuberculosis_H37Rv ------MAGPLSGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPS----
MMAR_4308|M.marinum_M ------MSGPLNGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSSAG
MUL_0986|M.ulcerans_Agy99 ------MSGPLNGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSSAG
MAV_1284|M.avium_104 ------MAGPLQGLRVVELSGIGPGPHAAMILGDLGADVVRIDRPS---G
Mflv_2126|M.gilvum_PYR-GCK ------MAGPLQGLRVVELAGIGPGPHAAMIFGDLGADVVRIERPGKGPG
Mvan_4578|M.vanbaalenii_PYR-1 ------MAGPLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPGKGPG
TH_4477|M.thermoresistible__bu ------MAGPLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPRNTPG
MSMEG_5184|M.smegmatis_MC2_155 ------MAGPLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPGKGGG
MAB_0845|M.abscessus_ATCC_1997 MADTGVKTGPLAGVKVIELGGIGPGPHAAMMLSDLGADVIRVRRPG---G
:*** *::*:**.**********::.******:*: **
Mb1175|M.bovis_AF2122/97 -SVDGISRDAMLRNRRIVTADLKSDQGLELALKLIAKADVLIEGYRPGVT
Rv1143|M.tuberculosis_H37Rv -SVDGISRDAMLRNRRIVTADLKSDQGLELALKLIAKADVLIEGYRPGVT
MMAR_4308|M.marinum_M -GRGGGVKDAMLRNRRIVTADLKSDQGRELVLKLVAKADVLIEGYRPGVT
MUL_0986|M.ulcerans_Agy99 -GRGGGVKDAMLRNRRIVTADLKSDQGRELVLKLVAKADVLIEGYRPGVT
MAV_1284|M.avium_104 -APGGVVKDAMSRNRRIVTADLKSDQGRELVLKLVAKADVLIEGYRPGVT
Mflv_2126|M.gilvum_PYR-GCK PATKPGG-DYLLRNRRSVAANLKSDEDREMVLRLIAKADVLIEGFRPGVT
Mvan_4578|M.vanbaalenii_PYR-1 PATKPGG-DYLLRNRRSVAANLKSEEDRDMVLRLIAKADVLIEGFRPGVT
TH_4477|M.thermoresistible__bu PGIPRGAKDHLLRNRRSVAADLKTEEGKELVRKLIAKADVLIEGYRPGVT
MSMEG_5184|M.smegmatis_MC2_155 --VPAGDRDAMLRNRRSVVADLKAPEGRDLVLQLVAKADVLIEGYRPGVT
MAB_0845|M.abscessus_ATCC_1997 LAIPAEETDLFHRGKRLVNLDVKKDP--EALLALVDKADVLLDPFRPGVC
* : *.:* * ::* : *: *****:: :****
Mb1175|M.bovis_AF2122/97 ERLGLGPEECAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHA
Rv1143|M.tuberculosis_H37Rv ERLGLGPEECAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHA
MMAR_4308|M.marinum_M ERLGLGPQDCAKVNDRLIYARMTGWGQAGPRSQQAGHDINYISLNGILHA
MUL_0986|M.ulcerans_Agy99 ERLGLGPQDCAKVNDRLIYARMTGWGQAGPRSQQAGHDINYISLNGILHA
MAV_1284|M.avium_104 ERLGLGPQDCAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHA
Mflv_2126|M.gilvum_PYR-GCK ERLGLGPEDCAKVNEKLVYARMTGWGQDGPRAQQAGHDINYISLNGVLHA
Mvan_4578|M.vanbaalenii_PYR-1 ERLGLGPHDCAKVNEKLIYARMTGWGQDGPRAQQAGHDINYISLNGALHA
TH_4477|M.thermoresistible__bu ERLGLGPEDCAKINPRLIYGRMTGWGQDGPRAQQAGHDINYISLNGTLHA
MSMEG_5184|M.smegmatis_MC2_155 ERLGLGPEDCAKVNERLIYARMTGWGQDGPRALQAGHDINYISLNGTLHA
MAB_0845|M.abscessus_ATCC_1997 ERIGIGPEECAKRNPRLIFARMTGWGQHGPMADRAGHDINYLSLTGALGS
**:*:**.:*** * :*::.******* ** : :*******:**.* * :
Mb1175|M.bovis_AF2122/97 IGRGDERPVPPLNLVGDFGGGSMFLLVGILAALWERQSSGKGQVVDAAMV
Rv1143|M.tuberculosis_H37Rv IGRGDERPVPPLNLVGDFGGGSMFLLVGILAALWERQSSGKGQVVDAAMV
MMAR_4308|M.marinum_M IGRVGERPVPPLNLVGDFGGGSMFLLVGILAALWERHNSGKGQVIDAAMV
MUL_0986|M.ulcerans_Agy99 IGRVGERPVPPLNLVGDFGGGSMFLLVGILAALWERHNSGKGQVIDAAMV
MAV_1284|M.avium_104 IGRANERPVPPLNLVGDFGGGSMFLLLGILSALWERQSSGKGQVVDAAMV
Mflv_2126|M.gilvum_PYR-GCK IGRHGERPVPPLNLAGDFGGGSMFLLVGVLAALWERERSGKGQVVDAAMV
Mvan_4578|M.vanbaalenii_PYR-1 IGRAGERPVPPLNLVGDFGGGSMFLLVGVLSALYERERSGKGQVVDAAMV
TH_4477|M.thermoresistible__bu VGRKGERPVPPLNLAGDFGGGSMFLLVGILAALFERQTSGKGQVVDAAMI
MSMEG_5184|M.smegmatis_MC2_155 VGRKGGRPVPPLNLAGDFGGGSMFLLVGILSALYERQASGKGQVIDAAMV
MAB_0845|M.abscessus_ATCC_1997 MGYKDRPPMPPMNLVADFGGGSMLLVQGILAALYEREKSGKGQVIDGAMV
:* . *:**:**..*******:*: *:*:**:**. ******:*.**:
Mb1175|M.bovis_AF2122/97 DGSSVLIQMMWAMRATGMWTDTRGANMLDGGAPYYDTYECADGRYVAVGA
Rv1143|M.tuberculosis_H37Rv DGSSVLIQMMWAMRATGMWTDTRGANMLDGGAPYYDTYECADGRYVAVGA
MMAR_4308|M.marinum_M DGSSVLVQMMWAMRGIGIWSDVRGTNMLDGGAPYYDTYECADGGYVAVGA
MUL_0986|M.ulcerans_Agy99 DGSSVLVQMMWAMRGIGIWSDVRGTNMLDGGAPYYDTYECADGGYVAVGA
MAV_1284|M.avium_104 DGSSVLVQMMWQMRASGMWTDARGTNLLDGGAPYYDTYECADGRYVAVGA
Mflv_2126|M.gilvum_PYR-GCK DGSSVLSMMMWSFRGMGMWSDERGVNMLDTGAPYYDTYECSDGRHIAVGC
Mvan_4578|M.vanbaalenii_PYR-1 DGSSVLSMMMWAFRGMGMWSDERGTNMLDTGAPYYDTYETADGKYVAVGA
TH_4477|M.thermoresistible__bu DGSAVLMQMMWAFRAMGMWSDERGVNMLDTGAPYYDTYETADGKYVAVGA
MSMEG_5184|M.smegmatis_MC2_155 DGSAVLMEMMWSFRANGMWSDERGTNMLDTGAPYYDTYETADGKYIAVGA
MAB_0845|M.abscessus_ATCC_1997 DGVSQLAQMQWTMYNNGLLFDEREAGLLDGGSPFYGTYETSDGKYMAVGS
** : * * * : *: * * ..:** *:*:*.*** :** ::***.
Mb1175|M.bovis_AF2122/97 IEPQFYAAMLAGLGLDAAELPPQNDRARWPELRALLTEAFASHDRDHWGA
Rv1143|M.tuberculosis_H37Rv IEPQFYAAMLAGLGLDAAELPPQNDRARWPELRALLTEAFASHDRDHWGA
MMAR_4308|M.marinum_M IEPQFYAAMLAGLGLDAVNLPPQNDVARWPELRAVLTEAFGRYDRDHWAK
MUL_0986|M.ulcerans_Agy99 IEPQFYAAMLAGLGLDAVNLPPQNDVARWPELRAVLTEAFGRYDRDHWAK
MAV_1284|M.avium_104 IEPQFYAAMLAGLGLDGADLPGQNDVSRWPELRAALTEKFASRDRDHWAK
Mflv_2126|M.gilvum_PYR-GCK IEPQFYAEFLKGVGLEGADLPGQNDMGRWPELREAFSKAIAAHDRDHWAG
Mvan_4578|M.vanbaalenii_PYR-1 IEPQFYAEMLKGIGLDGADLPDQNDMSRWPELREAFTKAFAAHDRDHWAK
TH_4477|M.thermoresistible__bu IEPQFYAEMLKGLGLEGEDLPDQNDMSRWDELRARFAEVFKSKDRDHWAQ
MSMEG_5184|M.smegmatis_MC2_155 IEPQFYAELLKGLGLDGADLPAQNDISRWPELREAFAKAFAAHDRAHWTK
MAB_0845|M.abscessus_ATCC_1997 IEPQFFAILVQGLGLDPESVPFQLDKARYPEMRKMFDDAFKTKTRDEWTE
*****:* :: *:**: .:* * * .*: *:* : . : * .*
Mb1175|M.bovis_AF2122/97 VFANSDACVTPVLAFGEVHNEPHIIERNTFYEAN-GGWQPMPAPRFSRTA
Rv1143|M.tuberculosis_H37Rv VFANSDACVTPVLAFGEVHNEPHIIERNTFYEAN-GGWQPMPAPRFSRTA
MMAR_4308|M.marinum_M VFADSDACVTPVLSFGEVHTEPHIAERNTFYEGDDGGPQPMPAPRFSRTV
MUL_0986|M.ulcerans_Agy99 VFADSDACVTPVLSFGEVHTEPHIAERNTFYEGDDGGPQPMPAPRFSRTV
MAV_1284|M.avium_104 VFADSDACVTPVLAFGEVQTEPHITERNTFYEVD-GGLQPLPAPRFSRTA
Mflv_2126|M.gilvum_PYR-GCK VFAGTDACVTPVLSFAEVESEPHNTERDTFYSEN-GSLYPAPAPRFSRSV
Mvan_4578|M.vanbaalenii_PYR-1 VFAGTDACVTPVLSFAEVESEPHNTERDTFYSEN-GSLYPAPAPRFSRSA
TH_4477|M.thermoresistible__bu VFAGTDACVTPVLSFAEVESEAHVVERNTFYREG-DHLLPAPAPRFSRSV
MSMEG_5184|M.smegmatis_MC2_155 VFEGTDACTTPVLSFAEVLDEPHVAERNTFYDDE-GNLQPMPAPRFSRTQ
MAB_0845|M.abscessus_ATCC_1997 IFIGTDACVSPVLTWGEAKQNEHLRDRGTIVDVD-GVTQAAPAPRFSRTP
:* .:***.:***::.*. : * :*.*: . . *******:
Mb1175|M.bovis_AF2122/97 SSQPRPPAATI-DIEAVLTDWDG
Rv1143|M.tuberculosis_H37Rv SSQPRPPAATI-DIEAVLTDWDG
MMAR_4308|M.marinum_M PSRPRPPAAPLTDVEAVLSDWV-
MUL_0986|M.ulcerans_Agy99 PSRPRPPAAPLTDVEAVLSDWA-
MAV_1284|M.avium_104 PETPR-PAAPVTDATAILDEWV-
Mflv_2126|M.gilvum_PYR-GCK PSAPKAPGVPGADTEAVLQEWV-
Mvan_4578|M.vanbaalenii_PYR-1 PSAPKPPGVPGADTEAVLREWV-
TH_4477|M.thermoresistible__bu PSAPTPPRDPGADTDAVLQDWQ-
MSMEG_5184|M.smegmatis_MC2_155 PGRPTPPPQRGADTEAVLRDWS-
MAB_0845|M.abscessus_ATCC_1997 SGPLGAPPKDTTELSDIG--W--
. * : : *