For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TQDMQEAPAPGYAGTRVPRVEDGRLLTGHGSFVDDISRPGMLHACFVRSPFAHARINGIDTTAALALPGV HAVFTAADLNADVKEAWHAVAGRDVADTPRPPLAERDAKFVGDPVALVVAESRYVAEDAIELVDIDYEPL PAITDFTRAQSSDVLVHESYPDNVAGGLAGAPPDEQTFATSPCVVTENIYQQMYAPVPIETRGLVAEWAR ASEELTLWASTQTPHELRAFCARLLGIAAQRVRVIMRDTGGGFGQKVVPMREDMCIMLAARKVPGALKWI EDRRENLMSAGQARHVDGTARMAFDSDGNIQAADVDFIMDIGAYPTPYPVLTTAAIGMFFPGPYRIPKAS FSYKTVFSNTSGLAAYRGPWQYETLAREILLDIAARKMGIDPIELRRRNLLRREEMPYVNPNGMPYDHVA PIETFEQAVKILDYEGFRREQREALAHGRYLGLGLSAYIEPTGAATGHLATEGATIRMEPTGKVNVYVNG GSSGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGAGTQCSRSGPMTAGAVNEAGKTLREKIVALA AHHLEVAESEVELAHSKAAVRGDPARQVTFGELAYTAYYSPQQLPSAMSPELEGTARFKSPNPIHWANAT HACTCEVDTQTGKVTLLRYVVSEDVGPMINPAVVEGQIAGGTVQGIGGALMENLAYDDDGNPLATTFVDY LLPTATEVPPIEYGHVEIPGPGPGGYKGAGEGGAIGSAPAVINAINDALAPLGVTVTRLPASPASVASLL AGASR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0588 | coxL_2 | - | 100% (776) | aerobic-type carbon monoxide dehydrogenase, CoxL_2 |
| M. ulcerans Agy99 | MUL_0115 | coxL | e-127 | 36.33% (779) | carbon monoxyde dehydrogenase (large chain), CoxL |
| M. ulcerans Agy99 | MUL_4580 | coxL_1 | 1e-45 | 26.19% (775) | carbon monoxyde dehydrogenase (large chain), CoxL_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0380c | - | 1e-131 | 37.61% (779) | carbon monoxyde dehydrogenase large subunit |
| M. gilvum PYR-GCK | Mflv_1573 | - | 0.0 | 76.74% (774) | carbon-monoxide dehydrogenase (acceptor) |
| M. tuberculosis H37Rv | Rv0373c | - | 1e-131 | 37.61% (779) | carbon monoxyde dehydrogenase large subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2925c | - | 2e-57 | 30.06% (785) | xanthine dehydrogenase family protein |
| M. marinum M | MMAR_0623 | coxL_3 | 0.0 | 98.32% (776) | aerobic-type carbon monoxide dehydrogenase, CoxL_3 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5880 | - | 0.0 | 79.64% (776) | nicotine dehydrogenase |
| M. thermoresistible (build 8) | TH_1269 | - | 0.0 | 79.95% (758) | nicotine dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5183 | - | 0.0 | 75.16% (789) | carbon-monoxide dehydrogenase (acceptor) |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0380c|M.bovis_AF2122/97 --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0588|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0623|M.marinum_M --------------------------------------------------
MSMEG_5880|M.smegmatis_MC2_155 --------------------------------------------------
TH_1269|M.thermoresistible__bu --------------------------------------------------
Mflv_1573|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5183|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDGAS
Mb0380c|M.bovis_AF2122/97 --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0588|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0623|M.marinum_M --------------------------------------------------
MSMEG_5880|M.smegmatis_MC2_155 --------------------------------------------------
TH_1269|M.thermoresistible__bu --------------------------------------------------
Mflv_1573|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5183|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 QHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTAGM
Mb0380c|M.bovis_AF2122/97 -MTTIESRPPSPEDLADNAQQPCGHGR------------------MMRKE
Rv0373c|M.tuberculosis_H37Rv -MTTIESRPPSPEDLADNAQQPCGHGR------------------MMRKE
MUL_0588|M.ulcerans_Agy99 -MTQD---------MQEAPAPGYAGTR------------------VPRVE
MMAR_0623|M.marinum_M -MTQD---------MQEAPAPRYAGTR------------------VQRVE
MSMEG_5880|M.smegmatis_MC2_155 -MTSA---------APETVTTRYAGRR------------------VERVE
TH_1269|M.thermoresistible__bu ---------------------------------------------VPRVE
Mflv_1573|M.gilvum_PYR-GCK -MTDADVQ------AVDAVSPRYAGQR------------------VPRVE
Mvan_5183|M.vanbaalenii_PYR-1 -MTDT---------ATNAVTARYAGQR------------------VPRVE
MAB_2925c|M.abscessus_ATCC_199 VLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRGSVSAPA
:
Mb0380c|M.bovis_AF2122/97 DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVK
Rv0373c|M.tuberculosis_H37Rv DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVK
MUL_0588|M.ulcerans_Agy99 DGRLLTGHGSFVDDISRPGMLHACFVRSPFAHARINGIDTTAALALPGVH
MMAR_0623|M.marinum_M DGRLLTGHGSFVDDISRPGMLHACFVRSPFAHARINGIDTATALALPGVH
MSMEG_5880|M.smegmatis_MC2_155 DTRLLTGRGTFVDDIVRPGMLHACFVRSPFAHAKINGIDATEALALPGVR
TH_1269|M.thermoresistible__bu DTRLLTGRGTFVDDIIRPGMLHACFVRSPFARATINGIDASAALAMPGVR
Mflv_1573|M.gilvum_PYR-GCK DSRLLTGQGRFVDDISRPGMLHACFVRSPFARATIRGIDTSAALALPGVH
Mvan_5183|M.vanbaalenii_PYR-1 DSRLLTGHGRFVDDISRPGMLHACFVRSPFAHATINGVDASAALALPGVH
MAB_2925c|M.abscessus_ATCC_199 AARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDTDRARLLPGVR
*.: * :. * .*: * ..: **.. * * :*. * * *:
Mb0380c|M.bovis_AF2122/97 AVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQGQEVASVVAE
Rv0373c|M.tuberculosis_H37Rv AVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQGQEVAFVVAE
MUL_0588|M.ulcerans_Agy99 AVFTAADLNADVKEAWHAVAGRDVADTPRPPLAERDAKFVGDPVALVVAE
MMAR_0623|M.marinum_M AVFTAADLNADVKEAWHAVAGRDVADTPRPPLAERDAKFVGDPVALVVAE
MSMEG_5880|M.smegmatis_MC2_155 AVFTAADINPEVKEAWHAVAGRDMPDTPRPPLAEGEVKFVGDPVAIVIAE
TH_1269|M.thermoresistible__bu AVFTAADINPEVKEAWHAVAGKDVPDTPRPPLAESEAKFVGDPVALVVAD
Mflv_1573|M.gilvum_PYR-GCK AVFTASDLNPDVREAWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAD
Mvan_5183|M.vanbaalenii_PYR-1 AVFTAADLNPDVKEAWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAD
MAB_2925c|M.abscessus_ATCC_199 AVLCYRDDPGVPFSTARHHERTDDPDD--TLVFDRVLRFAGQRVAAVVAD
**. * : * : :* *: ** *:*:
Mb0380c|M.bovis_AF2122/97 DRYSARDACELVDVDYEPRDPVVDARTALDP--------SAPVIRTDLEG
Rv0373c|M.tuberculosis_H37Rv DRYSARDACELVDVDYEPRDPVVDARTALDP--------SAPVIRTDLEG
MUL_0588|M.ulcerans_Agy99 SRYVAEDAIELVDIDYEPLPAITDFTRAQS---------SDVLVHESYPD
MMAR_0623|M.marinum_M SRYVAEDAIELVDIDYEPLPAITDFTRAQS---------SDVLVHESYPD
MSMEG_5880|M.smegmatis_MC2_155 SRYVAEDAVDLVEVDYEPLPAVVDFRTALT---------SPVAVHDAYPD
TH_1269|M.thermoresistible__bu SRYIAEDAIELVDVDYEPLPAVADFRQAVN---------SDVVVHEEYPD
Mflv_1573|M.gilvum_PYR-GCK SRYLAEDAVDLVEVDYEPLPAVADFRKAVGG-----ASAGVPVVHEAYPD
Mvan_5183|M.vanbaalenii_PYR-1 SRYLAEDAVDLVEVDYDPLPAVADFRKAVGG-----AEAGVPVVHAAYPD
MAB_2925c|M.abscessus_ATCC_199 TPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGDKGLGARIADPA
*. * : ::::*: .: * * :
Mb0380c|M.bovis_AF2122/97 KSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVAD
Rv0373c|M.tuberculosis_H37Rv KSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVAD
MUL_0588|M.ulcerans_Agy99 NVAG-----GLAGAPPDEQTFATSPCVVTENIYQQMYAPVPIETRGLVAE
MMAR_0623|M.marinum_M NVAG-----GLAGAPPDEQTFATSPCVVTENIYQQMYAPVPIETRGLVAE
MSMEG_5880|M.smegmatis_MC2_155 NNAG-----GMAGAPPDEETFDSAAHVVKEHVYQQVYVPVPIETRGLVVE
TH_1269|M.thermoresistible__bu NVAG-----GMAGAPPDEETFANAAHVVSEHIYQHAHVPVPIECRGIVAE
Mflv_1573|M.gilvum_PYR-GCK NVAG-----GMGGMPPDEELFATAPHVVEQHIYQQMYVPVPMETRGMVVE
Mvan_5183|M.vanbaalenii_PYR-1 NVAG-----GMGGMPPDEEIFATAAHVVEEHIYQQMYVPVPMETRGMVVE
MAB_2925c|M.abscessus_ATCC_199 RNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQHVHLETHGSVG-
. .. .. : ** . :* * *
Mb0380c|M.bovis_AF2122/97 LDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKV
Rv0373c|M.tuberculosis_H37Rv LDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKV
MUL_0588|M.ulcerans_Agy99 WARASEELTLWASTQTPHELRAFCARLLGIAAQRVRVIMRDTGGGFGQKV
MMAR_0623|M.marinum_M WAPASEELTLWASTQTPHELRAFCARLLGIAAQRVRVIMRDTGGGFGQKV
MSMEG_5880|M.smegmatis_MC2_155 WQASAGELTIWASTQTPHELRAFAARLLGIPAQHVRVIMRDTGGGFGQKV
TH_1269|M.thermoresistible__bu WQSASDELTIWASTQTPHELRAFAARLLGIPASRVRVIVKDTGGGFGQKV
Mflv_1573|M.gilvum_PYR-GCK WTSSTDELTIWASTQTPHELRAFAARLLGIPAQGVRVIMRDTGGAFGQKV
Mvan_5183|M.vanbaalenii_PYR-1 WTSTTNELTVWASTQTPHELRAFAARLLGIPAQGVRVIMRDTGGAFGQKV
MAB_2925c|M.abscessus_ATCC_199 WQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVRVFAPRVGGGFGAKQ
. .: :::*.*. * . : *:. :**: **.** *
Mb0380c|M.bovis_AF2122/97 PIYPGYVCAIVASL---LLD---------KPVKWMEDRSENLTSTGFARD
Rv0373c|M.tuberculosis_H37Rv PIYPGYVCAIVASL---LLD---------KPVKWMEDRSENLTSTGFARD
MUL_0588|M.ulcerans_Agy99 VPMREDMCIMLAAR---KVP---------GALKWIEDRRENLMSAGQARH
MMAR_0623|M.marinum_M VPMREDMCIMLAAR---KVP---------GALKWIEDRRENLMSAGQARH
MSMEG_5880|M.smegmatis_MC2_155 VPMREDMCIMLAAR---KTA---------GALKWIEDRRENLMSAGQSRH
TH_1269|M.thermoresistible__bu VPMREDMCIMIAAR---KVP---------APLKWIEDRRENLMAASQARH
Mflv_1573|M.gilvum_PYR-GCK VPMREDMCILLAAR---RVP---------AALKWIEDRRENLMSAGQSRH
Mvan_5183|M.vanbaalenii_PYR-1 VPMREDMCILLAAR---KMPTATSNAQSGVAVKWIEDRRENLMSAGQSRH
MAB_2925c|M.abscessus_ATCC_199 EMLTEDLVLLAVRVTGA-------------PVVYEFTRSDQFTIAPCRHP
: : . .: : * ::: : :
Mb0380c|M.bovis_AF2122/97 YIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSY
Rv0373c|M.tuberculosis_H37Rv YIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSY
MUL_0588|M.ulcerans_Agy99 VDGTARMAFDSDGNIQAADVDFIMDIGAY-PTPYPVLTTAAIGMFFPGPY
MMAR_0623|M.marinum_M VDGTARMAFDTDGNIQAADIDFIMDIGAY-PTPYPVLTTAAIGMFFPGPY
MSMEG_5880|M.smegmatis_MC2_155 VDGDVRMAFDPDGNILAADIDFVQDIGAY-PTPYPVLTTAAIGMFFPGPY
TH_1269|M.thermoresistible__bu VDGDVRMAFDADGTILAADIDFIQDIGSY-PTPYPVLTTAAIGMFFPGPY
Mflv_1573|M.gilvum_PYR-GCK VDGKVRMAFDDDGKILAADIDFIQDVGSY-PTPYPVLTTAAIGMFFPGPY
Mvan_5183|M.vanbaalenii_PYR-1 VDGKVRMAFDSDGKILAADIDFVQDVGSY-PTPYPVLTTAAIGMFFPGPY
MAB_2925c|M.abscessus_ATCC_199 MRVNVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHGCN--ESMAQY
* : ** : * :.: * *:: . . . . *
Mb0380c|M.bovis_AF2122/97 DIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMD
Rv0373c|M.tuberculosis_H37Rv DIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMD
MUL_0588|M.ulcerans_Agy99 RIPKASFSYKTVFSN-TSGLAAYRGPWQYETLAR--EILLDIAARKMGID
MMAR_0623|M.marinum_M RIPKASFSYKTVFSN-TSGLAAYRGPWQYETLAR--EILLDIAARKMGID
MSMEG_5880|M.smegmatis_MC2_155 RVPKASFNYKTVFSN-TAGLHAYRGPWQYETLSR--EILLDIAARKIGID
TH_1269|M.thermoresistible__bu RVPKASFNYKTVFSN-TAGLAAYRGPWQYETLSR--EILLDIAARKMGMD
Mflv_1573|M.gilvum_PYR-GCK RVPKASFNYKTVFSN-TPGLHAYRGPWQYETLTR--EMLLDCAARKIGMD
Mvan_5183|M.vanbaalenii_PYR-1 RVPKASFNYKTVFSN-TPGLHAYRGPWQYETLTR--EMLLDSAARKIGMD
MAB_2925c|M.abscessus_ATCC_199 RCANKRVDAQAVYTN-NIPSGAFRG-YGLGQVLFGIESALDELARNLGID
:*::* *: : * :* * :: :*
Mb0380c|M.bovis_AF2122/97 PAELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR
Rv0373c|M.tuberculosis_H37Rv PAELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR
MUL_0588|M.ulcerans_Agy99 PIELRRRNLLRREE---MPYVNPNGMPYDHVAPIETFEQAVKILDYEGFR
MMAR_0623|M.marinum_M PIELRRRNLLRREE---MPYVNPNGMPYDHVAPIETLEQAVKILDYEGFR
MSMEG_5880|M.smegmatis_MC2_155 PVELRRRNLLRRDE---MPYFNPNGMPYDHVAPAETFEQAVKILDHEGFR
TH_1269|M.thermoresistible__bu PVDLRRKNLLRRDE---MPYFNPNGMPYDHVAPIETFEQAVKMADHEGFR
Mflv_1573|M.gilvum_PYR-GCK PVELRRINILRGDE---MPFFNPNGMPYDNCAPADTFEQAVKILDHEGFR
Mvan_5183|M.vanbaalenii_PYR-1 PVELRRINILRGDE---MPFFNPNGMPYDNCAPADTFEQAVKILDHEGFR
MAB_2925c|M.abscessus_ATCC_199 PFEFRRRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAAD
* ::* *:: : . . :. : * . .
Mb0380c|M.bovis_AF2122/97 AEQKQR-RARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHP
Rv0373c|M.tuberculosis_H37Rv AEQKQR-RARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHP
MUL_0588|M.ulcerans_Agy99 REQREA-LAHGRYLGLGLSAYIEPTGAAT-------GHLATEGATIRMEP
MMAR_0623|M.marinum_M REQREA-LAHGRYLGLGLSAYIEPTGAAT-------GHLATEGATIRMEP
MSMEG_5880|M.smegmatis_MC2_155 KQQAEA-LAQGRYIGLGFSAYIEPTGAAT-------GHLASEGATIRMES
TH_1269|M.thermoresistible__bu KEQEEA-LAQGRYIGLGFSTYIEPTGAAT-------GHLAGEGATIRMES
Mflv_1573|M.gilvum_PYR-GCK KEQAEA-LAEGRYIGLGFSAYIEPTGAAT-------GNLATEGATVRMES
Mvan_5183|M.vanbaalenii_PYR-1 KEQADA-LAEGRYIGLGFSAYIEPTGAAT-------GNLATEGATIRMES
MAB_2925c|M.abscessus_ATCC_199 PARNGSDLPAGWKVGEGMAIAMIATVPPR---------GHVADARAELDA
: . * :* *:: .. . .. .:..
Mb0380c|M.bovis_AF2122/97 TGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGL
Rv0373c|M.tuberculosis_H37Rv TGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGL
MUL_0588|M.ulcerans_Agy99 TGKVNVYVNGGSSGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGA
MMAR_0623|M.marinum_M TGKVNVYVNGGSSGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGA
MSMEG_5880|M.smegmatis_MC2_155 TGKINVYVNGGSTGNSLETTVIQLTADALGADIDDVATIQGDTAVTPYGA
TH_1269|M.thermoresistible__bu TGKINVYVNGGSSGNSIETTVVQLTADALGADIDDVATIQGDTAVTPYGA
Mflv_1573|M.gilvum_PYR-GCK TGKINVYVNGGSAGNSIETTVVQLTADALGANIDDVATIQGDTAVTPYGA
Mvan_5183|M.vanbaalenii_PYR-1 TGKINVYVNGGSAGNSIETTVVQLTADALGANIEDVATIQGDTAVTPYGA
MAB_2925c|M.abscessus_ATCC_199 RGRYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDT
*: : :. *:. *. *:.* ** ::: :.** ....
Mb0380c|M.bovis_AF2122/97 GTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHV
Rv0373c|M.tuberculosis_H37Rv GTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHV
MUL_0588|M.ulcerans_Agy99 GTQCSRSGPMTAGAVNEAGKTLREKIVALAAHHLEVAESEVELAHSKAAV
MMAR_0623|M.marinum_M GTQGSRSGPMTAGAVNEAGKILREKIVALAAHHLEVAESEVELVHSKAAV
MSMEG_5880|M.smegmatis_MC2_155 GTQGSRSAPMTAGAVNEAGTMLRNQIVAMAAAWLGVEEPEIELGGSKATV
TH_1269|M.thermoresistible__bu GTQGSRSAPMTAGAVHEAGSILRKQIVTIAAHMLDTDESQIELAGSRAVV
Mflv_1573|M.gilvum_PYR-GCK GTQGSRSAPMTAGAVNEAGAILRTQIIAIAAQILGVEAAEIELANSRASV
Mvan_5183|M.vanbaalenii_PYR-1 GTQGSRSAPMTAGAVNEAGAILRRQIIAIGAQILGVEESEIELANSRAGV
MAB_2925c|M.abscessus_ATCC_199 GAFGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRA
*: * . .::. *. .. :* : :.: * . . . .
Mb0380c|M.bovis_AF2122/97 KGDPSAAVTIADIAMRAHG-AGDLPEGIEGGLDAEVCYNP---SNLTYPY
Rv0373c|M.tuberculosis_H37Rv KGDPSAAVTIADIAMRAHG-AGDLPEGIEGGLDAEVCYNP---SNLTYPY
MUL_0588|M.ulcerans_Agy99 RGDPARQVTFGELAYTAYYSPQQLPSAMSPELEGTARFKS--PNPIHWAN
MMAR_0623|M.marinum_M RGDPARQVTFGELAYTAYYSPQQLPSALSTELEGTARFKS--PNPIHWAN
MSMEG_5880|M.smegmatis_MC2_155 RSDPDKSVTFGQLAYRAYYEPQQLPPGLSASLEATARYTAPPTAPIHWAN
TH_1269|M.thermoresistible__bu RDDPDKSVSFADLAYRAYYEPQMLPPGTSATLEATARFTS--QAPIHWAN
Mflv_1573|M.gilvum_PYR-GCK RSDPEKSVSFADIAYRSYYDPGQLG-GVSPTLEATARFNS--QAMIHWAN
Mvan_5183|M.vanbaalenii_PYR-1 RNDPERSVSFADIAYRSYYDPAQLG-GVSPTLEATARFNS--QAMIHWAN
MAB_2925c|M.abscessus_ATCC_199 GADLLG--------------LTEIAASAPEPLSAVGHHEG---TPRSVAF
* : . *.. . .
Mb0380c|M.bovis_AF2122/97 GAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGM
Rv0373c|M.tuberculosis_H37Rv GAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGM
MUL_0588|M.ulcerans_Agy99 ATHACTCEVDTQTGKVTLLRYVVSEDVGPMINPAVVEGQIAGGTVQGIGG
MMAR_0623|M.marinum_M ATHACTCEVDTQTGKVTLLRYVVSEDVGPMINPAVVEGQIAGGTVQGIGG
MSMEG_5880|M.smegmatis_MC2_155 ATHACTCEVDIETGQVTLTRYIVSEDVGPMINPNVVEGQIAGGTVQGIGG
TH_1269|M.thermoresistible__bu ATHACTCEVDTVTGHVTLTNYVVSEDVGPMINPNVVEGQIAGGTVQGIGG
Mflv_1573|M.gilvum_PYR-GCK ATHVCTCEVDVETGHVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQGIGG
Mvan_5183|M.vanbaalenii_PYR-1 ATHVCTCEVDVETGQVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQGIGG
MAB_2925c|M.abscessus_ATCC_199 NVQAFRVAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGS
. : *. * : . : * * :** .**: ** .:.**
Mb0380c|M.bovis_AF2122/97 ALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAK
Rv0373c|M.tuberculosis_H37Rv ALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAK
MUL_0588|M.ulcerans_Agy99 ALMENLAYDDDGNPLATTFVDYLLPTATEVPPIEYGHVEIPGPG-PGGYK
MMAR_0623|M.marinum_M ALMENLAYDDDGNPLATTFVDYLLPTATEVPPIEYGHVEIPGPG-PGGYK
MSMEG_5880|M.smegmatis_MC2_155 ALLEQLAYDDAGNPLSSTFVDYLLPTATEVPAIEYGHVEIPGPG-VGGYK
TH_1269|M.thermoresistible__bu ALLEHQAYDADGNPLSSTFVDYLLPTATEVPLIEYGHIEVPGPG-VGGYK
Mflv_1573|M.gilvum_PYR-GCK ALLEKLAYDDDGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPG-VGGYK
Mvan_5183|M.vanbaalenii_PYR-1 ALLEKLAYDDAGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPG-VGGYK
MAB_2925c|M.abscessus_ATCC_199 ALYEEILVHD-GFVSTTALRNYHIPRLVDVPDTEVYFADTYDTFGPLGAK
** * . * :: :* :* :** * . .. * *
Mb0380c|M.bovis_AF2122/97 GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP
Rv0373c|M.tuberculosis_H37Rv GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP
MUL_0588|M.ulcerans_Agy99 GAGEGGAIGSAPAVINAINDALAPLGVTVTRLPASPASVASLLAGASR--
MMAR_0623|M.marinum_M GAGEGGAIGSAPAVINAINDALAPLGVTVTRLPASPASVASLLAGASR--
MSMEG_5880|M.smegmatis_MC2_155 GAGEGGAIGSTPAVINAVNDALAPLGVTITTLPASPAAISAAIEAAIETR
TH_1269|M.thermoresistible__bu GAGEGGAIGSTPAVINAINDALAALGVTVTRLPATPATIVELIEQATSKD
Mflv_1573|M.gilvum_PYR-GCK GAGEGGAIGSPPAVINAVNDALAPLGVTLTQLPATPATIVELIDAASRKD
Mvan_5183|M.vanbaalenii_PYR-1 GAGEGGAIGSPPAVINAINDALAPLGVTLTQLPATPATIVELIERAG-KD
MAB_2925c|M.abscessus_ATCC_199 SMSESPYNPVAPALANAIRDAVG---VRVYRLPMNAARVWRVINDSGGGE
. .*. .**: **: **:. * :* ..: : :
Mb0380c|M.bovis_AF2122/97 I---
Rv0373c|M.tuberculosis_H37Rv I---
MUL_0588|M.ulcerans_Agy99 ----
MMAR_0623|M.marinum_M ----
MSMEG_5880|M.smegmatis_MC2_155 GKDH
TH_1269|M.thermoresistible__bu QKWN
Mflv_1573|M.gilvum_PYR-GCK H---
Mvan_5183|M.vanbaalenii_PYR-1 H---
MAB_2925c|M.abscessus_ATCC_199 SS--