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TAAGPLTGIRVIEVGTMLAGPYATLLLADLGAKVVKIEPPGGEISRTVGESYFASLNRNKSGLCLDLNSE VGQHRLAELAADSDALVVNLRPSSIRRLGLTYEALRRFNVRIVCVAITGYGLHGGDDPAFDYVIQAAAGS AALTGEPGGPPTLPGYSSADNSTGMCAALGLLAAIISGRGGQVDVSLFDVMVSQLNYHAAAYLNEGTEPQ RRPHGVHPCYVPAQLFPTADGYLGLFVTHDGFWKAFAAEAGIHGFETMTERASRRAEVLTVVASALADRH RRRLGATAAAAGGARGSRSDAARGPRGESPSDRARGRNAPRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0364 | - | - | 100% (323) | acyl-CoA transferase |
| M. ulcerans Agy99 | MUL_4811 | - | 1e-34 | 32.54% (295) | hypothetical protein MUL_4811 |
| M. ulcerans Agy99 | MUL_2446 | - | 3e-31 | 31.97% (319) | hypothetical protein MUL_2446 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 2e-30 | 29.64% (307) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_2390 | - | 1e-118 | 72.66% (278) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 2e-30 | 29.64% (307) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 5e-42 | 34.86% (327) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_4795 | - | 1e-155 | 93.29% (298) | acyl-CoA transferase |
| M. avium 104 | MAV_0859 | - | 1e-126 | 74.83% (294) | caib/baif family protein |
| M. smegmatis MC2 155 | MSMEG_4877 | - | 1e-120 | 76.09% (276) | CaiB/BaiF family protein |
| M. thermoresistible (build 8) | TH_2523 | - | 1e-120 | 72.64% (296) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. vanbaalenii PYR-1 | Mvan_4258 | - | 1e-120 | 72.64% (296) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0364|M.ulcerans_Agy99 -MTAAG--PLTGIRVIEVGTMLAGPYATLLLADLGAKVVKIE-PPGGEIS
MMAR_4795|M.marinum_M -MTAAG--PLTGIRVIEVGTMLAGPYATLLLADLGAEVVKIE-PPGGEIS
Mflv_2390|M.gilvum_PYR-GCK -MSAGA--PLAGIRILEVGVMLAGPYATMMLADLGAEVIKIE-PPGGEIS
Mvan_4258|M.vanbaalenii_PYR-1 -MSSG---PLAGIRILEVGVMLAGPYATMMLADLGAEVIKIE-PPGGEIS
MSMEG_4877|M.smegmatis_MC2_155 -MSACASAPLAGIRVIEVGVMLAGPYATMMLADLGAEVIKIE-PPGGEIS
TH_2523|M.thermoresistible__bu -MTNST-APLAGIRILEVGTMLAGPYATMMLADLGAEVIKIE-PPDGEIS
MAV_0859|M.avium_104 -MSGNNTGPLAGIRILEVGTMLAGPYSTMLLADLGAEVTKIE-PAGGEIS
MAB_0824|M.abscessus_ATCC_1997 -MTAAA---LDGLLVVDFSRVLAGPYATMMLGDFGAEVIKIERPVLGDDT
Mb3300|M.bovis_AF2122/97 MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
Rv3272|M.tuberculosis_H37Rv MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
: * *: :::. :*** : :* *:**:* *:* *
MUL_0364|M.ulcerans_Agy99 RTVG--------ESYFASLNRNKSGLCLDLNSEVGQHRLAELAADSDALV
MMAR_4795|M.marinum_M RTVG--------ESYFASLNRNKSGLCLDLNSEVGQHRLAELAAESDALV
Mflv_2390|M.gilvum_PYR-GCK RQVS--------DSYFASLNRNKQSVVIDLRSDAGRQKLGELVADSHALL
Mvan_4258|M.vanbaalenii_PYR-1 RQVS--------DSYFASLNRNKQSVVLDLRSEQGRRRLGELVADSHALL
MSMEG_4877|M.smegmatis_MC2_155 RQVG--------DSYFASLNRGKRSLCLDLASANGKARLAELVADSHALL
TH_2523|M.thermoresistible__bu RQVG--------DSYFASLNRNKRSVCLDLTSAEGQAELGALVAQSHALL
MAV_0859|M.avium_104 RSVG--------ATYFASLNRNKSSICLDLNSDAGQRRLGELSAESHALL
MAB_0824|M.abscessus_ATCC_1997 RQWGPPYDSDGQATYFNSVNRNKQSVVLDLTSPDGQHRARELAGRADVVV
Mb3300|M.bovis_AF2122/97 QITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVL
Rv3272|M.tuberculosis_H37Rv QITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVL
: . :** . **.* .: :** : .: . * :..::
MUL_0364|M.ulcerans_Agy99 VNLRPSSIRRLGLTYEALRRFNVRIVCVAITGYG--LHGGDDPAFDYVIQ
MMAR_4795|M.marinum_M VNLRPSSIRRLGLTYEALRRFNERIVCVAITGYG--LHGGDDPAFDYVIQ
Mflv_2390|M.gilvum_PYR-GCK VNMKPSAIRRLGLTYDSLKEFNERIVCVAMTGFG--LDGGDDPAFDYVIQ
Mvan_4258|M.vanbaalenii_PYR-1 VNMKPSAIRRLGLTYDSLREFNESIVCVAMTGFG--LDGGDDPAFDYVIQ
MSMEG_4877|M.smegmatis_MC2_155 VNMKPSVIRRLGLTYDALKEFNPEIVCVAMTGFG--LDGGDDPAFDYVIQ
TH_2523|M.thermoresistible__bu VNMKPSVIRRLGLTYEALRRHNERIVCVALTGYG--LDGGDDPAFDYVIQ
MAV_0859|M.avium_104 VNLKPSAIRRLRLTYDDLRRHNEKIVCVAITGFG--LYGGDDPAFDYVVQ
MAB_0824|M.abscessus_ATCC_1997 ENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFGR-GAGADLPGYDLLVQ
Mb3300|M.bovis_AF2122/97 EAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVA
Rv3272|M.tuberculosis_H37Rv EAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVA
::.. :.:: * : *: * :: :*.:* .. *. * ::
MUL_0364|M.ulcerans_Agy99 AAAGSAALTGEPGGPPTLPGYSSADNSTGMCAALGLLAAIIS----GRGG
MMAR_4795|M.marinum_M AAAGSAALTGEPGGPPTLPGYSSADNSTGMCAALGLLAAIIS----GRGG
Mflv_2390|M.gilvum_PYR-GCK AATGVAAMTGDPDGPPTLPGYSSADNSTGLTAALGLLAQIVS----GRGG
Mvan_4258|M.vanbaalenii_PYR-1 AATGVAAMTGDPQGPPTLPGYSSADNSTGLTAALGLLAQIVS----GRGG
MSMEG_4877|M.smegmatis_MC2_155 AATGVAAMTGDPDGPPTLPGYSSADNSTGLTAALGLLAMIVS----GRGG
TH_2523|M.thermoresistible__bu AATGIAALTGDPDGPPTLPGYSSADNSTGLTAALGLLAMIVS----GRGG
MAV_0859|M.avium_104 AGVGTAALTGDPDGPPTLPGYSSADNSTGMCAALGLLAKIIS----GTGG
MAB_0824|M.abscessus_ATCC_1997 AVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGILAALSYRDRTGQGQ
Mb3300|M.bovis_AF2122/97 AEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVAD
Rv3272|M.tuberculosis_H37Rv AEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVAD
* * : . * .* :. .:** : * .
MUL_0364|M.ulcerans_Agy99 QVDVSLFDVMVSQLNYHAAAYLNEGTEPQ---------RRPHGVHPCYVP
MMAR_4795|M.marinum_M QVDVSLFDVMVSQLNYHAAAYLNDGTEPQ---------RRPHGAHPYYVP
Mflv_2390|M.gilvum_PYR-GCK QVDVSLQDVMLSQLNYRAAAYLNDGAEPK---------RHPFGAHSYYVP
Mvan_4258|M.vanbaalenii_PYR-1 QVDVSLQDVMLSQLNYRAAAYLNDGIEPQ---------RHPNGAHSYYVP
MSMEG_4877|M.smegmatis_MC2_155 QVDVSLRDVMLSQLNYRASAYLNDGAEPR---------RHPNGAHSYYVP
TH_2523|M.thermoresistible__bu QVDVSLRDVMLSQLNYRASAWLNDGVEPR---------RLPYGAHSYYVP
MAV_0859|M.avium_104 QVDVSLRDVMLSQLNYHASAYLNSGVEPQ---------RRPHGAHSYYVP
MAB_0824|M.abscessus_ATCC_1997 RVDTDLMSVLLSSLVNQASGYLGAGVVPE---------ALGN-RHPSIAP
Mb3300|M.bovis_AF2122/97 VVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQP
Rv3272|M.tuberculosis_H37Rv VVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQP
*:. : .* :. : *. . . *
MUL_0364|M.ulcerans_Agy99 AQLFPTADGYLGLFVTHDGFWKAFAAEAGIH------GFETMTERASRRA
MMAR_4795|M.marinum_M AQLFPTADGYLGLFVTHDGFWKAFAAEAGIH------GFETMAERASRRA
Mflv_2390|M.gilvum_PYR-GCK AQLFSTAEGFLALFITHDGFWASFAREAGIE------GFATMAERASRRD
Mvan_4258|M.vanbaalenii_PYR-1 AQLFPTADGYLALFITHDGFWAAFAAEAGIE------GFPTMAERAERRD
MSMEG_4877|M.smegmatis_MC2_155 AQLFPTADGYLALFITHDGFWRSFAGEAGIS------GFETMAERAARRD
TH_2523|M.thermoresistible__bu AQLFPTADGYLALFITHDGFWRTFAAEAGID------GFPTMAERAARRS
MAV_0859|M.avium_104 AQLFPTAEGYLALFITHDGFWKSFAAEAGIG------GFETMAERVARRD
MAB_0824|M.abscessus_ATCC_1997 YQTFETADRPIAIAVGNDKQFRLLVQALEMPRLARDDRFATNPLRVRHRG
Mb3300|M.bovis_AF2122/97 SDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQRSRSINYA
Rv3272|M.tuberculosis_H37Rv SDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQRSRSINYA
: * **: : : : : * * .
MUL_0364|M.ulcerans_Agy99 EVLTVVASALADR----HRRRLGATAAAAGGARGSRSDAA--------RG
MMAR_4795|M.marinum_M EVLTVVASALATDTAAGWERRLRPLGVPAAAVRTLPEALA--------EN
Mflv_2390|M.gilvum_PYR-GCK EVLALVSAALAGDTAVGWKNRLQPLGIPAAAVRTLPEALE--------AM
Mvan_4258|M.vanbaalenii_PYR-1 EVLALVSAALETDTAANWQHRLRPLGIPVAAVRTLPEALT--------AT
MSMEG_4877|M.smegmatis_MC2_155 EVLHVVTATLATDSAASWEKRLKPLGIPVAAVRTLPEALS--------ET
TH_2523|M.thermoresistible__bu EVLDVVTGALAADTALGWEKRLRPLGIPAAAVRTLPEALA--------DT
MAV_0859|M.avium_104 EVLAVVTAMLSTDSAAGWERRLRPLGVPAAAVRTLPEALE--------AT
MAB_0824|M.abscessus_ATCC_1997 ELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIAEAFR--------FA
Mb3300|M.bovis_AF2122/97 ELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAESDLT
Rv3272|M.tuberculosis_H37Rv ELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAENDLT
*: : * * . . . . .
MUL_0364|M.ulcerans_Agy99 P-----RGES---------PSDRARGRNAPRR----------------
MMAR_4795|M.marinum_M PQVIVRAGELRLVGNPIRVSGYRPEYRPAPLLGEHCR-----------
Mflv_2390|M.gilvum_PYR-GCK PEVVVTAGDFRLVRSPIRIAGYTPEYRPAPTLDEHADAPAHSS-----
Mvan_4258|M.vanbaalenii_PYR-1 PEALITAGEFRLVGSPIRIAGYQPAYRPAPRLDEHADAAAHSS-----
MSMEG_4877|M.smegmatis_MC2_155 PEALVTAGDFRLVGSSIRIAGYQPDYRPPPAFDEYAGGQAQARSQSSS
TH_2523|M.thermoresistible__bu PEAVVTAGEFRLVRSPIQVTGYEPDYLPPPALDRRATRQSS-------
MAV_0859|M.avium_104 PEVVVTAGEFRLVGSPIHVSGYQPEYRPPPQLPQS-------------
MAB_0824|M.abscessus_ATCC_1997 ERLGLDVAVTVPGSPEPQVANPISMSKTPVVYRNGPPRLGQSRA----
Mb3300|M.bovis_AF2122/97 LEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEHNAVFLARP----
Rv3272|M.tuberculosis_H37Rv LEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEHNAVFLARP----
.. . .