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SSGPLAGIRILEVGVMLAGPYATMMLADLGAEVIKIEPPGGEISRQVSDSYFASLNRNKQSVVLDLRSEQ GRRRLGELVADSHALLVNMKPSAIRRLGLTYDSLREFNESIVCVAMTGFGLDGGDDPAFDYVIQAATGVA AMTGDPQGPPTLPGYSSADNSTGLTAALGLLAQIVSGRGGQVDVSLQDVMLSQLNYRAAAYLNDGIEPQR HPNGAHSYYVPAQLFPTADGYLALFITHDGFWAAFAAEAGIEGFPTMAERAERRDEVLALVSAALETDTA ANWQHRLRPLGIPVAAVRTLPEALTATPEALITAGEFRLVGSPIRIAGYQPAYRPAPRLDEHADAAAHSS *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4258 | - | - | 100% (351) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. vanbaalenii PYR-1 | Mvan_1855 | - | 3e-49 | 34.25% (362) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. vanbaalenii PYR-1 | Mvan_4959 | - | 4e-46 | 35.37% (376) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 6e-34 | 28.04% (378) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_2390 | - | 1e-177 | 88.57% (350) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 6e-34 | 28.04% (378) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 2e-44 | 34.57% (324) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_4795 | - | 1e-153 | 75.44% (342) | acyl-CoA transferase |
| M. avium 104 | MAV_0859 | - | 1e-156 | 78.01% (341) | caib/baif family protein |
| M. smegmatis MC2 155 | MSMEG_4877 | - | 1e-168 | 83.67% (349) | CaiB/BaiF family protein |
| M. thermoresistible (build 8) | TH_2523 | - | 1e-160 | 81.05% (343) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_0364 | - | 1e-121 | 72.64% (296) | acyl-CoA transferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4258|M.vanbaalenii_PYR-1 -MSSG---PLAGIRILEVGVMLAGPYATMMLADLGAEVIKIE-PPGGEIS
Mflv_2390|M.gilvum_PYR-GCK -MSAGA--PLAGIRILEVGVMLAGPYATMMLADLGAEVIKIE-PPGGEIS
MSMEG_4877|M.smegmatis_MC2_155 -MSACASAPLAGIRVIEVGVMLAGPYATMMLADLGAEVIKIE-PPGGEIS
TH_2523|M.thermoresistible__bu -MTNST-APLAGIRILEVGTMLAGPYATMMLADLGAEVIKIE-PPDGEIS
MAV_0859|M.avium_104 -MSGNNTGPLAGIRILEVGTMLAGPYSTMLLADLGAEVTKIE-PAGGEIS
MMAR_4795|M.marinum_M -MTAAG--PLTGIRVIEVGTMLAGPYATLLLADLGAEVVKIE-PPGGEIS
MUL_0364|M.ulcerans_Agy99 -MTAAG--PLTGIRVIEVGTMLAGPYATLLLADLGAKVVKIE-PPGGEIS
MAB_0824|M.abscessus_ATCC_1997 -MTAAA---LDGLLVVDFSRVLAGPYATMMLGDFGAEVIKIERPVLGDDT
Mb3300|M.bovis_AF2122/97 MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
Rv3272|M.tuberculosis_H37Rv MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
: * *: :::. :*** : :* *:**:* *:* *
Mvan_4258|M.vanbaalenii_PYR-1 RQVS--------DSYFASLNRNKQSVVLDLRSEQGRRRLGELVADSHALL
Mflv_2390|M.gilvum_PYR-GCK RQVS--------DSYFASLNRNKQSVVIDLRSDAGRQKLGELVADSHALL
MSMEG_4877|M.smegmatis_MC2_155 RQVG--------DSYFASLNRGKRSLCLDLASANGKARLAELVADSHALL
TH_2523|M.thermoresistible__bu RQVG--------DSYFASLNRNKRSVCLDLTSAEGQAELGALVAQSHALL
MAV_0859|M.avium_104 RSVG--------ATYFASLNRNKSSICLDLNSDAGQRRLGELSAESHALL
MMAR_4795|M.marinum_M RTVG--------ESYFASLNRNKSGLCLDLNSEVGQHRLAELAAESDALV
MUL_0364|M.ulcerans_Agy99 RTVG--------ESYFASLNRNKSGLCLDLNSEVGQHRLAELAADSDALV
MAB_0824|M.abscessus_ATCC_1997 RQWGPPYDSDGQATYFNSVNRNKQSVVLDLTSPDGQHRARELAGRADVVV
Mb3300|M.bovis_AF2122/97 QITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVL
Rv3272|M.tuberculosis_H37Rv QITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVL
: . :** . **.* .: :** : .: . * :..::
Mvan_4258|M.vanbaalenii_PYR-1 VNMKPSAIRRLGLTYDSLREFNESIVCVAMTGFG--LDGGDDPAFDYVIQ
Mflv_2390|M.gilvum_PYR-GCK VNMKPSAIRRLGLTYDSLKEFNERIVCVAMTGFG--LDGGDDPAFDYVIQ
MSMEG_4877|M.smegmatis_MC2_155 VNMKPSVIRRLGLTYDALKEFNPEIVCVAMTGFG--LDGGDDPAFDYVIQ
TH_2523|M.thermoresistible__bu VNMKPSVIRRLGLTYEALRRHNERIVCVALTGYG--LDGGDDPAFDYVIQ
MAV_0859|M.avium_104 VNLKPSAIRRLRLTYDDLRRHNEKIVCVAITGFG--LYGGDDPAFDYVVQ
MMAR_4795|M.marinum_M VNLRPSSIRRLGLTYEALRRFNERIVCVAITGYG--LHGGDDPAFDYVIQ
MUL_0364|M.ulcerans_Agy99 VNLRPSSIRRLGLTYEALRRFNVRIVCVAITGYG--LHGGDDPAFDYVIQ
MAB_0824|M.abscessus_ATCC_1997 ENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFGR-GAGADLPGYDLLVQ
Mb3300|M.bovis_AF2122/97 EAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVA
Rv3272|M.tuberculosis_H37Rv EAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVA
::.. :.:: * : *: * :: :*.:* .. *. * ::
Mvan_4258|M.vanbaalenii_PYR-1 AATGVAAMTGDPQGPPTLPGYSSADNSTGLTAALGLLAQIVS----GRGG
Mflv_2390|M.gilvum_PYR-GCK AATGVAAMTGDPDGPPTLPGYSSADNSTGLTAALGLLAQIVS----GRGG
MSMEG_4877|M.smegmatis_MC2_155 AATGVAAMTGDPDGPPTLPGYSSADNSTGLTAALGLLAMIVS----GRGG
TH_2523|M.thermoresistible__bu AATGIAALTGDPDGPPTLPGYSSADNSTGLTAALGLLAMIVS----GRGG
MAV_0859|M.avium_104 AGVGTAALTGDPDGPPTLPGYSSADNSTGMCAALGLLAKIIS----GTGG
MMAR_4795|M.marinum_M AAAGSAALTGEPGGPPTLPGYSSADNSTGMCAALGLLAAIIS----GRGG
MUL_0364|M.ulcerans_Agy99 AAAGSAALTGEPGGPPTLPGYSSADNSTGMCAALGLLAAIIS----GRGG
MAB_0824|M.abscessus_ATCC_1997 AVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGILAALSYRDRTGQGQ
Mb3300|M.bovis_AF2122/97 AEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVAD
Rv3272|M.tuberculosis_H37Rv AEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVAD
* * : . * .* :. .:** : * .
Mvan_4258|M.vanbaalenii_PYR-1 QVDVSLQDVMLSQLNYRAAAYLNDGIEPQ---------RHPNGAHSYYVP
Mflv_2390|M.gilvum_PYR-GCK QVDVSLQDVMLSQLNYRAAAYLNDGAEPK---------RHPFGAHSYYVP
MSMEG_4877|M.smegmatis_MC2_155 QVDVSLRDVMLSQLNYRASAYLNDGAEPR---------RHPNGAHSYYVP
TH_2523|M.thermoresistible__bu QVDVSLRDVMLSQLNYRASAWLNDGVEPR---------RLPYGAHSYYVP
MAV_0859|M.avium_104 QVDVSLRDVMLSQLNYHASAYLNSGVEPQ---------RRPHGAHSYYVP
MMAR_4795|M.marinum_M QVDVSLFDVMVSQLNYHAAAYLNDGTEPQ---------RRPHGAHPYYVP
MUL_0364|M.ulcerans_Agy99 QVDVSLFDVMVSQLNYHAAAYLNEGTEPQ---------RRPHGVHPCYVP
MAB_0824|M.abscessus_ATCC_1997 RVDTDLMSVLLSSLVNQASGYLGAGVVPE---------ALGN-RHPSIAP
Mb3300|M.bovis_AF2122/97 VVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQP
Rv3272|M.tuberculosis_H37Rv VVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQP
*:. : .* :. : *. . . *
Mvan_4258|M.vanbaalenii_PYR-1 AQLFPTADGYLALFITHDGFWAAFAAEAGIE------GFPTMAERAERRD
Mflv_2390|M.gilvum_PYR-GCK AQLFSTAEGFLALFITHDGFWASFAREAGIE------GFATMAERASRRD
MSMEG_4877|M.smegmatis_MC2_155 AQLFPTADGYLALFITHDGFWRSFAGEAGIS------GFETMAERAARRD
TH_2523|M.thermoresistible__bu AQLFPTADGYLALFITHDGFWRTFAAEAGID------GFPTMAERAARRS
MAV_0859|M.avium_104 AQLFPTAEGYLALFITHDGFWKSFAAEAGIG------GFETMAERVARRD
MMAR_4795|M.marinum_M AQLFPTADGYLGLFVTHDGFWKAFAAEAGIH------GFETMAERASRRA
MUL_0364|M.ulcerans_Agy99 AQLFPTADGYLGLFVTHDGFWKAFAAEAGIH------GFETMTERASRRA
MAB_0824|M.abscessus_ATCC_1997 YQTFETADRPIAIAVGNDKQFRLLVQALEMPRLARDDRFATNPLRVRHRG
Mb3300|M.bovis_AF2122/97 SDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQRSRSINYA
Rv3272|M.tuberculosis_H37Rv SDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQRSRSINYA
: * **: : : : : * * .
Mvan_4258|M.vanbaalenii_PYR-1 EVLALVSAALETDTAANWQHRLRPLGIPVAAVRTLPEALT--------AT
Mflv_2390|M.gilvum_PYR-GCK EVLALVSAALAGDTAVGWKNRLQPLGIPAAAVRTLPEALE--------AM
MSMEG_4877|M.smegmatis_MC2_155 EVLHVVTATLATDSAASWEKRLKPLGIPVAAVRTLPEALS--------ET
TH_2523|M.thermoresistible__bu EVLDVVTGALAADTALGWEKRLRPLGIPAAAVRTLPEALA--------DT
MAV_0859|M.avium_104 EVLAVVTAMLSTDSAAGWERRLRPLGVPAAAVRTLPEALE--------AT
MMAR_4795|M.marinum_M EVLTVVASALATDTAAGWERRLRPLGVPAAAVRTLPEALA--------EN
MUL_0364|M.ulcerans_Agy99 EVLTVVASALADR----HRRRLGATAAAAGGARGSRSDAA--------RG
MAB_0824|M.abscessus_ATCC_1997 ELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIAEAFR--------FA
Mb3300|M.bovis_AF2122/97 ELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAESDLT
Rv3272|M.tuberculosis_H37Rv ELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAENDLT
*: : * * . . . . .
Mvan_4258|M.vanbaalenii_PYR-1 PEALITAGEFRLVGSPIRIAGYQPAYRPAPRLDEHADAAAHSS-----
Mflv_2390|M.gilvum_PYR-GCK PEVVVTAGDFRLVRSPIRIAGYTPEYRPAPTLDEHADAPAHSS-----
MSMEG_4877|M.smegmatis_MC2_155 PEALVTAGDFRLVGSSIRIAGYQPDYRPPPAFDEYAGGQAQARSQSSS
TH_2523|M.thermoresistible__bu PEAVVTAGEFRLVRSPIQVTGYEPDYLPPPALDRRATRQSS-------
MAV_0859|M.avium_104 PEVVVTAGEFRLVGSPIHVSGYQPEYRPPPQLPQS-------------
MMAR_4795|M.marinum_M PQVIVRAGELRLVGNPIRVSGYRPEYRPAPLLGEHCR-----------
MUL_0364|M.ulcerans_Agy99 P-----RGES---------PSDRARGRNAPRR----------------
MAB_0824|M.abscessus_ATCC_1997 ERLGLDVAVTVPGSPEPQVANPISMSKTPVVYRNGPPRLGQSRA----
Mb3300|M.bovis_AF2122/97 LEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEHNAVFLARP----
Rv3272|M.tuberculosis_H37Rv LEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEHNAVFLARP----
.. . .