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M. thermoresistible (build 8) TH_2460 (-)

annotation: putative transcriptional regulator, MerR family
coordinates: 2260129 - 2260422
length: 98

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2460--100% (98)putative transcriptional regulator, MerR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_0148-2e-0830.11% (93) MerR family transcriptional regulator
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0009-1e-0830.77% (91) transcriptional regulator
M. avium 104MAV_1646-2e-0539.71% (68) transcriptional regulator, MerR family protein
M. smegmatis MC2 155MSMEG_2194-2e-0628.57% (91) MerR-family protein transcriptional regulator
M. ulcerans Agy99MUL_0011-4e-0830.77% (91) transcriptional regulator
M. vanbaalenii PYR-1Mvan_1919-5e-0728.57% (91) MerR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0009|M.marinum_M               ---------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRA
MUL_0011|M.ulcerans_Agy99           ---------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPSRRA
Mvan_1919|M.vanbaalenii_PYR-1       MTSGTTLTYVTQEMQVDELTVGEVAERFGITVRTLHHYDEIGLLTPGRRC
Mflv_0148|M.gilvum_PYR-GCK          ---------MTQETRMEELTVGEVAKRFGITIRTLHHYDHIGLLTPEQRN
MSMEG_2194|M.smegmatis_MC2_155      ---------------MEELTVGEVAKRFRITVRTLHHYDEIGLLSPSRRV
TH_2460|M.thermoresistible__bu      -----------------------------------------------VRT
MAV_1646|M.avium_104                --------------MAEQLLIGDVTALTGIASGRIRHYEKIGLLH-ADHL
                                                                                    : 

MMAR_0009|M.marinum_M               ASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLD-EGNAVSHLVRQR-
MUL_0011|M.ulcerans_Agy99           ASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLD-EGNAVSHLVRQR-
Mvan_1919|M.vanbaalenii_PYR-1       ASGYRVYTPADLTRLSQVIVYRRLDFSLDEIASLLD-EGNEVSHLIRQR-
Mflv_0148|M.gilvum_PYR-GCK          ASGYRVYTSADLTRLSQIIVYRRLEMSLDEIASVLD-EGDEISHLRRQR-
MSMEG_2194|M.smegmatis_MC2_155      TSGYRVYTPADLTRLSQIIVYRRLEFSLDEIASLLD-EGDAVSHLLRQR-
TH_2460|M.thermoresistible__bu      AAGYRGDTDAAIERLHLIPVYRSAGLPLEEIRALLDGAADPLARLQRQH-
MAV_1646|M.avium_104                SNGYRVFDVEQVLDLLRIDLMRSLGVGINDIQRLLHGGHSTLADLLDEHR
                                    : ***      :  *  : : *   . :::*  :*.   . :: *  :: 

MMAR_0009|M.marinum_M               ERVMARLDEMKDLVEAIDQALEKAMTNTP-------------MTDDDMR-
MUL_0011|M.ulcerans_Agy99           ERVMARLDEMKDLVEAIDLALEKAMTNTP-------------MTDDDMR-
Mvan_1919|M.vanbaalenii_PYR-1       ERVMSRLDEMKDLVAAIDQALEKAMTNTP-------------MTDDDMR-
Mflv_0148|M.gilvum_PYR-GCK          ERVMSRLDELTELVGAIDQALENAMTNTP-------------MTDDDMR-
MSMEG_2194|M.smegmatis_MC2_155      ERVMARLGEMKDLVAAIDQALEKAMTNTP-------------MTDDDMR-
TH_2460|M.thermoresistible__bu      ALLLEQADRLQHTIKAVEELMNAHRHGIQ-------------LSAEEQV-
MAV_1646|M.avium_104                ALLIQQRDRLDQLIRALDESCAQSRAAADGTDVSEHLLRQLATTHRDSIG
                                      :: : ..: . : *::                         :  :   

MMAR_0009|M.marinum_M               --------------ELFGDGFDDYRAETEQKWGETTEWKESQRRTRSYGK
MUL_0011|M.ulcerans_Agy99           --------------ELFGDGFDDYRVETEQKWGETAEWKESQRRTKSYGK
Mvan_1919|M.vanbaalenii_PYR-1       --------------ELFGDGFDDYQAEAEQKWGETAEWKESQRRTKSYGK
Mflv_0148|M.gilvum_PYR-GCK          --------------ELFGDSFDDYQAEAEQKWGETAEWKESQRRATSYGK
MSMEG_2194|M.smegmatis_MC2_155      --------------ELFGEGFDDYQAEAERKFGDTAEWKESQRRTKSYSK
TH_2460|M.thermoresistible__bu      --------------EIFGS--AVFR-------------------------
MAV_1646|M.avium_104                VIGRLSAPLPAPVAAMYADLFDEWDLPVPALFGQMRLPSAASTLLAQLAE
                                                   ::..    :                          

MMAR_0009|M.marinum_M               DEWVRIKAEGQAVEKTLSDAFRAGLPADSEEAMNAAEQHRRHVN------
MUL_0011|M.ulcerans_Agy99           DEWVRIKAEGQAIEKALSDAFRAGLPADSEEAMNAAEQHRRHVN------
Mvan_1919|M.vanbaalenii_PYR-1       DEWVQIKSEGEAVEKALSDAFRAGLPPDSAEAMNAAEQHRLHVN------
Mflv_0148|M.gilvum_PYR-GCK          DDWVRIKAEGQAVEKALADAFRAGLPADSEEAMNAAEQHRHHVN------
MSMEG_2194|M.smegmatis_MC2_155      GQWIQLKDEGEAVEKALADAFRGGLAPDSEVAMDAAEQHRLHVN------
TH_2460|M.thermoresistible__bu      --------------------------------------------------
MAV_1646|M.avium_104                TPGRQVLFDRLRRLAADVIALGESVSAATELAHNWIEQQLADPLPDDVVT
                                                                                      

MMAR_0009|M.marinum_M               ---------RWFYDCPPAFHRSLGDMYVSDPRYIATYDESFGLPGLAAYC
MUL_0011|M.ulcerans_Agy99           ---------RWFYDCPPAFHRNLGDMYVSDPRYIATYDESFGLPGLAAYC
Mvan_1919|M.vanbaalenii_PYR-1       ---------RWFYDCPPAFHRKLGDMYVSDPRYVATYDESFGLPGLAAYC
Mflv_0148|M.gilvum_PYR-GCK          ---------RWFYDCPPAFHRTLGDMYVSDPRYVATYDESFGLPGLARYC
MSMEG_2194|M.smegmatis_MC2_155      ---------RWFYDCPPDFHRKLGDMYVSDPAYVARYDESFGLPGLAAFC
TH_2460|M.thermoresistible__bu      --------------------------------------------------
MAV_1646|M.avium_104                VLRGVQPLLGQDPVIVQGFRAWAGSISPAAARFIEEIARQTARRGLAAVS
                                                                                      

MMAR_0009|M.marinum_M               REAIHANANRTGG----
MUL_0011|M.ulcerans_Agy99           REAIHANANRAGG----
Mvan_1919|M.vanbaalenii_PYR-1       REAIHANADRAGQ----
Mflv_0148|M.gilvum_PYR-GCK          RDAIHANADRS------
MSMEG_2194|M.smegmatis_MC2_155      RDAIHANADRAGGDVTG
TH_2460|M.thermoresistible__bu      -----------------
MAV_1646|M.avium_104                VIVLPAADRAQTADATP