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VVILLPMVTFTMAYLIVDVPKPGDIRTNQVSTILASDGSEIAKIVPPEGNRVDVNLSQVPMHVRQAVIAA EDRNFYSNPGFSFTGFARAVKNNLFGGDLQGGSTITQQYVKNALVGSAQHGWSGLMRKAKELVIATKMSG EWSKDDVLQAYLNIIYFGRGAYGISAASKAYFDKPVEQLTVAEGALLAALIRRPSTLDPAVDPEGAHARW NWVLDGMVETKALSPNDRAAQVFPETVPPDLARAENQTKGPNGLIERQVTRELLELFNIDEQTLNTQGLV VTTTIDPQAQRAAEKAVAKYLDGQDPDMRAAVVSIDPHNGAVRAYYGGDNANGFDFAQAGLQTGSSFKVF ALVAALEQGIGLGYQVDSSPLTVDGIKITNVEGEGCGTCNIAEALKMSLNTSYYRLMLKLNGGPQAVADA AHQAGIASSFPGVAHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASGIYHPPHFVQKVVSANGQ VLFDASTADNTGDQRIPKAVADNVTAAMEPIAGYSRGHNLAGGRDSAAKTGTTQFGDTTANKDAWMVGYT PSLSTAVWVGTVKGDEPLVTASGAAIYGSGLPSDIWKATMDGALKGTSNETFPKPTEVGGYAGVPPPPPP PEVPPSETVIQPTVEIAPGITIPIGPPTTITLAPPPPAPPAATPTPPP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0050 | ponA1 | - | 100% (678) | PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE (PEPTIDOGLYCAN TGASE) + PENICILLIN-SENSITIVE TRANSPEPTIDASE (DD-TRANSPEPTIDASE) |
| M. tuberculosis H37Rv | Rv3682 | ponA2 | 2e-51 | 26.22% (740) | bifunctional membrane-associated penicillin-binding protein |
| M. tuberculosis H37Rv | Rv0016c | pbpA | 2e-12 | 25.67% (409) | penicillin-binding protein PbpA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0051 | ponA1 | 0.0 | 99.56% (680) | bifunctional penicillin-binding protein 1A/1B |
| M. gilvum PYR-GCK | Mflv_0871 | - | 0.0 | 75.77% (685) | glycosyl transferase family protein |
| M. leprae Br4923 | MLBr_02688 | ponA | 0.0 | 82.77% (679) | penicillin-bonding protein |
| M. abscessus ATCC 19977 | MAB_4901c | - | 0.0 | 71.45% (690) | penicillin-binding protein |
| M. marinum M | MMAR_0069 | ponA1 | 0.0 | 91.76% (680) | bifunctional penicillin-binding protein 1A/1B PonA1 |
| M. avium 104 | MAV_0071 | - | 0.0 | 87.46% (678) | transglycosylase |
| M. smegmatis MC2 155 | MSMEG_6900 | - | 0.0 | 78.85% (681) | penicillin-binding protein 1 |
| M. thermoresistible (build 8) | TH_3201 | - | 0.0 | 77.71% (664) | PUTATIVE glycosyl transferase, family 51 |
| M. ulcerans Agy99 | MUL_0068 | ponA1 | 0.0 | 91.03% (680) | bifunctional penicillin-binding protein 1A/1B PonA1 |
| M. vanbaalenii PYR-1 | Mvan_6036 | - | 0.0 | 77.96% (685) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0871|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6036|M.vanbaalenii_PYR-1 ---------------------------MGARNPQHRKDDPVRRPGEGGVR
MSMEG_6900|M.smegmatis_MC2_155 --------------------------------------------------
TH_3201|M.thermoresistible__bu --------------------------------------------MRLSTL
Rv0050|M.tuberculosis_H37Rv --------------------------------------------------
Mb0051|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0069|M.marinum_M --------------------------------------------------
MUL_0068|M.ulcerans_Agy99 --------------------------------------------------
MAV_0071|M.avium_104 MSSNNEGRHSQSSGDQRGPAAEQGAGERRETARPDADPQRRNGPSTSSRR
MLBr_02688|M.leprae_Br4923 --------------------------------------------------
MAB_4901c|M.abscessus_ATCC_199 ---------------------------------MVGEENSVAPNSGPDSP
Mflv_0871|M.gilvum_PYR-GCK --MPPDDRHTAVLPPFRDGPPPPTRDPIDAVKSALDSRDRR---------
Mvan_6036|M.vanbaalenii_PYR-1 RAPAPDDRHTTVIPPVRDGAPPPLRDPIDAVKRALDGGAR----------
MSMEG_6900|M.smegmatis_MC2_155 --MPPDDRLTAVLPPVRDGDIAP---PIDVVRAALE--------------
TH_3201|M.thermoresistible__bu ATTAAAVALTGTVGGLATGPAARSRWFARLKKPGFQPPAQ----------
Rv0050|M.tuberculosis_H37Rv --------------------------------------------------
Mb0051|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0069|M.marinum_M --------------------------------------------------
MUL_0068|M.ulcerans_Agy99 --------------------------------------------------
MAV_0071|M.avium_104 RQAPPDDRLTTILPPVDDDRAPRRSDPIEEVKAALAGPPSTPLRRDALDE
MLBr_02688|M.leprae_Br4923 --------------------------------------------------
MAB_4901c|M.abscessus_ATCC_199 RTPSTDDRPTSILDPIEDLPLYRRDDDAVAAARAALERDED---------
Mflv_0871|M.gilvum_PYR-GCK ----------RRDGDRRREGDQRRGS-GPPPPPPGPPRHGGGGPTGGDGP
Mvan_6036|M.vanbaalenii_PYR-1 -------------GERKNFGPPKQPPPSQPPPPPGRP-PGGGGPPGGGGP
MSMEG_6900|M.smegmatis_MC2_155 ------------------------GSPPPKPPPPPPPGRGGGGPSGPGGP
TH_3201|M.thermoresistible__bu -------------------AFPIVWPILYTDIAGVSAATIDRLXXXPGEP
Rv0050|M.tuberculosis_H37Rv --------------------------------------------------
Mb0051|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0069|M.marinum_M --------------------------------------------------
MUL_0068|M.ulcerans_Agy99 --------------------------------------------------
MAV_0071|M.avium_104 VKAALDSRGPASGRQQRAGLGGRPPVGPPPPPPRRGWSGGPGGPGGRGSG
MLBr_02688|M.leprae_Br4923 ------------------------------------------MPGSRLNR
MAB_4901c|M.abscessus_ATCC_199 -----------------------GGRGHEPPPPPGTP-----GRPGGSSR
Mflv_0871|M.gilvum_PYR-GCK SGPPRSLREQINWTWVRRGSLIAAVVLIVLPLLTFGMAYMIVDVPKPGDI
Mvan_6036|M.vanbaalenii_PYR-1 AGPRRSLREQINWKWVRRGSIIAAAVLILLPLLTFGMAYMIVDVPKPGDI
MSMEG_6900|M.smegmatis_MC2_155 SGPGRQFR--INWKWVRRGSAIAVAVMVLLPLITFGMAYMIVDVPEPGDI
TH_3201|M.thermoresistible__bu PEEPANWFDRINWRWVRRGLFAGAVALLVLPIITFVMAYLIVDVPRPGDI
Rv0050|M.tuberculosis_H37Rv -------------------------MVILLPMVTFTMAYLIVDVPKPGDI
Mb0051|M.bovis_AF2122/97 -------------------------MVILLLMVTFTMAYLIVDVPKPGDI
MMAR_0069|M.marinum_M ---------------MRRSAYLAAAVVILLPIVTFTMAYFIVDVPRPGDI
MUL_0068|M.ulcerans_Agy99 -------------------------MVILLPIVTFTVAYFIVDVPRPGDI
MAV_0071|M.avium_104 PWRDWSWTQQINWLWVRRAAYLCAAVLVLLPIVTFAMAYFIVDIPKPGDL
MLBr_02688|M.leprae_Br4923 TWLLHLN-RQVNWRWVRYSLYLAVVVLLLLPIVTFTMTYFMVKVPRPGDI
MAB_4901c|M.abscessus_ATCC_199 PPQRRRKRKSNGWKIFRNVMIALVLLAIVIPLATFALAYSVVDIPKPGDI
::: : ** ::* :*.:*.***:
Mflv_0871|M.gilvum_PYR-GCK RTAQVSTILASDGS-EIAKIVPPEGNRIDVNIDQIPVHVRDAVMAAEDRD
Mvan_6036|M.vanbaalenii_PYR-1 RTAQVSTILASDGS-EIAKIVPPEGNRVDVDIDQIPVHVRDAVMAAEDRD
MSMEG_6900|M.smegmatis_MC2_155 RTPQVSTILASDGS-EIARIVPPEGNRVDVKIDQIPVHVRDAVMAAEDRD
TH_3201|M.thermoresistible__bu RTNQVSTILASDGS-ELARIVPPEGNRIDVNINQIPVHVRDAVMAAEDRD
Rv0050|M.tuberculosis_H37Rv RTNQVSTILASDGS-EIAKIVPPEGNRVDVNLSQVPMHVRQAVIAAEDRN
Mb0051|M.bovis_AF2122/97 RTNQVSTILASDGS-EIAKIVPPEGNRVDVNLSQVPMHVRQAVIAAEDRN
MMAR_0069|M.marinum_M RTNQVSTILASDGS-EIAKIVPPEGNRVDVNLSQVPEHVRAAVIAAEDRG
MUL_0068|M.ulcerans_Agy99 RTNQVSTILASDGS-EIAKIVPPEGNRVDVNLSQVPEHVRAAVIAAEDRG
MAV_0071|M.avium_104 RTNQVSTILASDGS-EIAKIIPPEGNRVDVNLNQVPVHVRQAVIAAEDRN
MLBr_02688|M.leprae_Br4923 RTNQVSTILANNGL-EIAKIVPPEGNRVDVNLSQVPVHVRQAVIAAEDRN
MAB_4901c|M.abscessus_ATCC_199 RTSQVSTILASDGTTELAKVVPPEGNRVDIKIDQVPQHVRAAVMAAEDRD
** *******.:* *:*:::******:*:.:.*:* *** **:*****.
Mflv_0871|M.gilvum_PYR-GCK FYSNPGFSFTGFLRAFKNNIFGG-DLQGGSTITQQYVKNALVGDARSGVG
Mvan_6036|M.vanbaalenii_PYR-1 FYSNPGFSFTGFLRAAKNNIFGG-DLQGGSTITQQYVKNALVGDARSGVG
MSMEG_6900|M.smegmatis_MC2_155 FYSNPGFSWTGFLRAIKNNLFGGGGLQGGSTITQQYVKNALVGDERSGIG
TH_3201|M.thermoresistible__bu FYSNPGFSFTGFARAIGNNIFGG-DVQGGSTITQQYVKNALVGSERVGVR
Rv0050|M.tuberculosis_H37Rv FYSNPGFSFTGFARAVKNNLFG-GDLQGGSTITQQYVKNALVGSAQHGWS
Mb0051|M.bovis_AF2122/97 FYSNPGFSFTGFARAVKNNLFG-GDLQGGSTITQQYVKNALVGSAQHGWS
MMAR_0069|M.marinum_M FYSNPGFSFSGFARAIKNNLFG-GDLQGGSTITQQYVKNALVGSAQHGWS
MUL_0068|M.ulcerans_Agy99 FYSNPGFSFSGFARAIKNNLFG-GDLQGGSTITQQYVKNALVGSAQHGWS
MAV_0071|M.avium_104 FYSNPGFDFSGFARAVNNNLFGNGDLQGGSTITQQYVKNALVGSAQHGVS
MLBr_02688|M.leprae_Br4923 FYSNPGFDFRASVRAVQNNLFGSGDLQGGSTITQQYVKNALVGSAQHGFD
MAB_4901c|M.abscessus_ATCC_199 FYGNPGFSFSGLLRAVKNNMFG-GDTQGGSTITQQYVKNAMVGSQRAGLG
**.****.: . ** **:** . **************:**. : *
Mflv_0871|M.gilvum_PYR-GCK GVIRKAKELVISTKMSSEWSKDQVLQSYLNIIYFGRGAYGVAAAAKAYFG
Mvan_6036|M.vanbaalenii_PYR-1 GLIRKAKELVISTKMSSEWSKDQVLQSYLNIIYFGRGAYGVAAAAQAYFG
MSMEG_6900|M.smegmatis_MC2_155 GLIRKAKELVISTKMSGEWSKDAVLQAYLNIIYFGRGAYGISAASKAYFD
TH_3201|M.thermoresistible__bu GLIRKAKELVISTKMSRQWSKDQVMQSYLNIIYFGRGAYGVAAASRAYFD
Rv0050|M.tuberculosis_H37Rv GLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRGAYGISAASKAYFD
Mb0051|M.bovis_AF2122/97 GLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRGAYGISAASKAYFD
MMAR_0069|M.marinum_M GLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRGAYGISAASKAYFD
MUL_0068|M.ulcerans_Agy99 GLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRGAYGISAASKAYFD
MAV_0071|M.avium_104 GLMRKAKELVIATKMSGEWSKDEVLQSYLNIIYFGRGAYGISAAAKAYFD
MLBr_02688|M.leprae_Br4923 GLMRKTKELVIAIKMSDAWSKDDVLQSYLNIIYFGRGAYGISAAAKAYFD
MAB_4901c|M.abscessus_ATCC_199 GLTRKAKEIVISTKMSQSWSKDQVMEAYLNIIYFGRGAYGISAASKAYFD
*: **:**:**: *** **** *:::*************::**::***.
Mflv_0871|M.gilvum_PYR-GCK KPIEEVTVSEGALLAALIQRPSVLDPAVDPDASAVRWSWVLDGMVEIGAL
Mvan_6036|M.vanbaalenii_PYR-1 KPVEQLNVSEGALLAALIQRPSVLDPAVDPDASAVRWSWVLDGMVEIGAL
MSMEG_6900|M.smegmatis_MC2_155 KPVEQLDVAEGALLAALIQRPSTLDPAVDPEGAADRWNWVLDGMVDIGAL
TH_3201|M.thermoresistible__bu KPVEELNVAEGALLAALIQRPSTLDPAADPQGAETRWNWVLDGMVEIGAL
Rv0050|M.tuberculosis_H37Rv KPVEQLTVAEGALLAALIRRPSTLDPAVDPEGAHARWNWVLDGMVETKAL
Mb0051|M.bovis_AF2122/97 KPVEQLTVAEGALLAALIRRPSTLDPAVDPEGAHARWNWVLDGMVETKAL
MMAR_0069|M.marinum_M KPVEQLTVSEGALLAALIRRPSTLDPAVDPDGALARWNWVLDGMVDTKAL
MUL_0068|M.ulcerans_Agy99 KPVEQLTVSEGALLAALIRRPSTLDPAVDPDGALARWNWVLDGMVDTKAL
MAV_0071|M.avium_104 KPVEQLTVSEGALLAALIRRPSTLDPAVDPKGALARWNWVLDGMVETKAL
MLBr_02688|M.leprae_Br4923 KPVEQLTCSEGALLAALIRRPSVLDPAINLKGVTARWNWVLDGMVDINAL
MAB_4901c|M.abscessus_ATCC_199 KPVEQLTVSEGALLAALIQRPSRLDPAVDLPESTNRWNWVLDGMVTIGAL
**:*:: :*********:*** **** : **.******* **
Mflv_0871|M.gilvum_PYR-GCK SEQDRAAQIFPPTIPPDQASTQNQTTGPNGLIERQVVSELMEIFDINEQA
Mvan_6036|M.vanbaalenii_PYR-1 SPEDRAGQVFPPTIPPDQAFTQNQTTGPNGLIERQVVNELMEIFDINEQT
MSMEG_6900|M.smegmatis_MC2_155 SQADRDAQVFPPTVPPDYAFQQNQTTGPNGLIERQVTNELLDLFDINEQT
TH_3201|M.thermoresistible__bu SPQERAAQVFPPTVPPELARSQNQTTGPNGLIERQVTRELLELFNISEQA
Rv0050|M.tuberculosis_H37Rv SPNDRAAQVFPETVPPDLARAENQTKGPNGLIERQVTRELLELFNIDEQT
Mb0051|M.bovis_AF2122/97 SPNDRAAQVFPETVPPDLARAENQTKGPNGLIERQVTRELLELFNIDEQT
MMAR_0069|M.marinum_M SAKDRAEQVFPRTVPPDQARAANQTTGPNGLIERQVTKELLELFNIDEQT
MUL_0068|M.ulcerans_Agy99 SAKDRAEQAFPRTVPPDQARAANQTTGPNGLIERQVTKELLELFNIDEQT
MAV_0071|M.avium_104 PAKDRAAQVFPQTVPPDQARAQNQTTGPNGLIERQVTKELMELFNIDERT
MLBr_02688|M.leprae_Br4923 SPNDRSVQLFPATVPPDQARAQNQTTGPNGLIERQVVKELFELFNIDRQT
MAB_4901c|M.abscessus_ATCC_199 SAQDRAGQVYPATVPPEQAAAQNATTGPNGLIKRQVMAELTDLFNIDEQT
. :* * :* *:**: * * *.******:*** ** ::*:*..::
Mflv_0871|M.gilvum_PYR-GCK LNTEGLQITTTIDPKAQSAAQDAVEDYLDGQDPDMRSAVVSIDPKTGGIK
Mvan_6036|M.vanbaalenii_PYR-1 LNTEGLQITTTIDPQMQAAAVDAVEEYMDGQDPDMRTAVVSIDPRTGGVR
MSMEG_6900|M.smegmatis_MC2_155 LNTEGLQITTTIDPKAQEAAVDAVDKYLEGQDPDMRAAVVSIDPRTGGIK
TH_3201|M.thermoresistible__bu LNTEGLQITTTIDPQAQQAAVDAVETYLEGQDPDMRAAVVSIDPRTGAVK
Rv0050|M.tuberculosis_H37Rv LNTQGLVVTTTIDPQAQRAAEKAVAKYLDGQDPDMRAAVVSIDPHNGAVR
Mb0051|M.bovis_AF2122/97 LNTQGLVVTTTIDPQAQRAAEKAVAKYLDGQDPDMRAAVVSIDPHNGAVR
MMAR_0069|M.marinum_M LNTQGLQVTTTIDAQAQQAAEKAVAKYLDGQDPEMRAAVVSIDPHNGAVR
MUL_0068|M.ulcerans_Agy99 LNTQGLQVTTTIDAQAQQAAEKAVAKYLDGQDPEMRAAVVSIDPHNGAVR
MAV_0071|M.avium_104 LNTQGLQVTTTIDPKAQQAAEKAVSKYLDGQDPDMRAAVVSVDPHDGAIR
MLBr_02688|M.leprae_Br4923 LNTQGLQVITTIDPQAQRIVEKAVSKYLDGQDPDMRAAIVSIDPHNGAIR
MAB_4901c|M.abscessus_ATCC_199 LNTEGLQITTTIDTKAQQAAENAVNTTLQSENPDLRTAVVSIDPRTGAVK
***:** : ****.: * . .** ::.::*::*:*:**:**: *.::
Mflv_0871|M.gilvum_PYR-GCK AYYGGSDAAGFDFAQAGLPTGSSFKVFALIAALEQGMGLGYQVDSSPLEV
Mvan_6036|M.vanbaalenii_PYR-1 AYYGGSDANGFDFAQAGLPTGSSFKVFALVAALQQGMGLGYQVDSSPVEV
MSMEG_6900|M.smegmatis_MC2_155 AYYGGSDANGFDFAQAGLPTGSSFKVFALVAALQQGIGLGYQIDSGPLEV
TH_3201|M.thermoresistible__bu AYYGGSDANGYDFAQAAVPTGSSFKVFALVAALEQGMGLGYQVDSSPLTV
Rv0050|M.tuberculosis_H37Rv AYYGGDNANGFDFAQAGLQTGSSFKVFALVAALEQGIGLGYQVDSSPLTV
Mb0051|M.bovis_AF2122/97 AYYGGDNANGFDFAQAGLQTGSSFKVFALVAALEQGIGLGYQVDSSPLTV
MMAR_0069|M.marinum_M AYYGGDNANGFDFAQAGLQTGSSFKVFALVAALEQGIGLGYDVDSSPLTV
MUL_0068|M.ulcerans_Agy99 AYYGGDNANGFDFAQAGLQTGSSFKVFALVAALEQGIGLGYDVDSSPLTV
MAV_0071|M.avium_104 AYYGGSDANGFDFAQAGLQTGSSFKVFCLIAALEQGIGLGYQVDSSPLTV
MLBr_02688|M.leprae_Br4923 AYYGGADANGFDFAQAGLQTGSSFKVFALIAALEQGIGLGYRVDSSPLTV
MAB_4901c|M.abscessus_ATCC_199 AYYGGSNAQGLDYAQQGLQTGSSFKVFALVAALQQGIGLGYQLDSSELTY
***** :* * *:** .: ********.*:***:**:**** :**. :
Mflv_0871|M.gilvum_PYR-GCK NGIKISNVEGSSCGSCNIAEALKRSLNTSYYRLMLKLKNGPQDVADAAHQ
Mvan_6036|M.vanbaalenii_PYR-1 NGIKISNVEGNSCGTCNIAEALKRSLNTSYYRLMLQLENGPQDVADAAHA
MSMEG_6900|M.smegmatis_MC2_155 NGIKIGNVEGEGCGTCSIAEALKRSLNTSYYRLMLKLENGPADVAEAAHD
TH_3201|M.thermoresistible__bu NGIEITNVEGSSCGRCNIAEALKRSLNTSFYRLMLELKNGPEDVADAAHR
Rv0050|M.tuberculosis_H37Rv DGIKITNVEGEGCGTCNIAEALKMSLNTSYYRLMLKLNGGPQAVADAAHQ
Mb0051|M.bovis_AF2122/97 DGIKITNVEGEGCGTCNIAEALKMSLNTSYYRLMLKLNGGPQAVADAAHQ
MMAR_0069|M.marinum_M DGIKITNVEGESCGTCNIAQALKMSLNTSYYRLMLKLKGGPEAVADAAHQ
MUL_0068|M.ulcerans_Agy99 DGIKITNVEGESCGTCNIAQALKMSLNTPYYRLMLKLKGGPEAVADAAHQ
MAV_0071|M.avium_104 DGIKITNVEGESCGTCNIAQALKMSLNTSYYRLMLKLKGGPQAVADAAHQ
MLBr_02688|M.leprae_Br4923 DGIKITNNGDESCGNCNIAEALKLSLNTSYYRLMLKLKNGPQAVADAAHQ
MAB_4901c|M.abscessus_ATCC_199 QGITIKNSEDASCGTCSVAEALKRSLNTSFYRLMLKLKNGPEDVAAAAHN
:** * * . .** *.:*:*** ****.:*****:*:.** ** ***
Mflv_0871|M.gilvum_PYR-GCK AGIAESIPGIEHTLSEDGQGGPPNNGIVLGQYQSRVLDMASAYATIAASG
Mvan_6036|M.vanbaalenii_PYR-1 AGIAESFPGVEHTLSEDGQGGPPNNGVVLGQYQSRVIDMASAYATLAASG
MSMEG_6900|M.smegmatis_MC2_155 AGVAESFPGVEHTLSEDGKGGPPNNGVVLGQYQSRVLDMASAYATLAASG
TH_3201|M.thermoresistible__bu AGIAESIPGIEHTLSEDGKGGPPNNGIVLGQYQSRPIDMASAYATLANSG
Rv0050|M.tuberculosis_H37Rv AGIASSFPGVAHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG
Mb0051|M.bovis_AF2122/97 AGIASSFPGVAHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG
MMAR_0069|M.marinum_M AGIATSFPGVPHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG
MUL_0068|M.ulcerans_Agy99 AGIATSFPGVPHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG
MAV_0071|M.avium_104 AGVATSFPGVDHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG
MLBr_02688|M.leprae_Br4923 AGIVSSFPGVAHTLSEDGKGGPPNNGIVLGQYETRVIDMASAYATLAASG
MAB_4901c|M.abscessus_ATCC_199 AGIAENFPGVSHTLSEDGQGGPPNNGVVLGQYQTRVLDMASAYATLAASG
**:. .:**: *******:*******:*****::* :********:* **
Mflv_0871|M.gilvum_PYR-GCK VYHKPHFVQKVVNSDGQVLFDATQEDNSGEQRIDQAVAENVIAAMQPIAG
Mvan_6036|M.vanbaalenii_PYR-1 VYHKPHFVQKVVNAEGTVLFDASQEDNTGEQRIDKAVADNVTAAMQPIAA
MSMEG_6900|M.smegmatis_MC2_155 VYHKPHFVEKVVNSSGQVLFDASKEDN-GEERIDKAVADNVTSAMQPIAG
TH_3201|M.thermoresistible__bu VYHRPHFVQKVVNSEGQVLFDADQRDDDGEQRIEKDVADNVTAAMQPIAA
Rv0050|M.tuberculosis_H37Rv IYHPPHFVQKVVSANGQVLFDASTADNTGDQRIPKAVADNVTAAMEPIAG
Mb0051|M.bovis_AF2122/97 IYHPPHFVQKVVSANGQVLFDASTADNTGDQRIPKAVADNVTAAMEPIAG
MMAR_0069|M.marinum_M IYHRPHFVQKVVNADGRVLFDASTEDNTGDQRIPKAVADNVTAAMEPIAG
MUL_0068|M.ulcerans_Agy99 IYHRPHFVQKVVDADGRVLFDASTEDNTGDQRIPKAVADNVTAAMEPIAG
MAV_0071|M.avium_104 VYHRPHFVQKVVNSDGQVLFDAGKSDNNGEQRIPKAVADNVTAAMEPIAG
MLBr_02688|M.leprae_Br4923 VYHRPHLVQKVVNAEGRVLFDASTADNSGDQRIAKAVADNVTAAMQPIAG
MAB_4901c|M.abscessus_ATCC_199 TYRKPHFIQKVVNADGQVLFDAGSSDNTGEKRISDDVANNAISAMKPIAA
*: **:::***.:.* ***** *: *::** . **:*. :**:***.
Mflv_0871|M.gilvum_PYR-GCK YS-GRALAGGRPSAAKTGTNQLGDTGENRDAWMVGFTPSLSTAVWVGTVD
Mvan_6036|M.vanbaalenii_PYR-1 YSNGHALAGGRPSAAKTGTNQLGDTGANRDAWMVGFTPSLSTAVWVGTTD
MSMEG_6900|M.smegmatis_MC2_155 WSRGHNLAGGRPSAAKTGTVQLGDTGDNRDAWMVGYTPSLSTAVWVGTTE
TH_3201|M.thermoresistible__bu YSNGHALAGGRPSAAKTGTHQLGDTGENRDAWMVGYTPSLSTAVWVGTVD
Rv0050|M.tuberculosis_H37Rv YSRGHNLAGGRDSAAKTGTTQFGDTTANKDAWMVGYTPSLSTAVWVGTVK
Mb0051|M.bovis_AF2122/97 YSRGHNLAGGRDSAAKTGTTQFGDTTANKDAWMVGYTPSLSTAVWVGTVK
MMAR_0069|M.marinum_M YSRGHNLAGGRPSASKTGTVQLGDTSANRDAWMVGYTPSLSTAVWVGTVK
MUL_0068|M.ulcerans_Agy99 YSRGHNLAGGRPSASKTGTVQLGDTSANRDAWMVGYTPSLSTAVWVGTVK
MAV_0071|M.avium_104 YSRGHALAGGRPSAAKTGTTQLGDTTSNKDAWMVGYTPSLSTAVWLGTAK
MLBr_02688|M.leprae_Br4923 YSRGHNLAGGRPSAAKTGTVQLGDTTANKDAWMVGYTPSLSTAVWVGTVK
MAB_4901c|M.abscessus_ATCC_199 YSRGHALAGGRESASKTGTAQLGDTKDNKDAWMVGFTPSLSTAVWVGTDD
:* *: ***** **:**** *:*** *:******:*********:** .
Mflv_0871|M.gilvum_PYR-GCK GTKPLVTSGGASVYGSGLPGQIWKSTMDNALDGTDNETFPKPEEIGGYAG
Mvan_6036|M.vanbaalenii_PYR-1 GTKPLENKWGSPVYGSGLPSDIWKATMDGALDGTDNESFPKPEEIGGYAG
MSMEG_6900|M.smegmatis_MC2_155 GVKPLVNKWGSPIYGSGLPSDIWKATMDGALEGTDVESFPKPTEIGGYAG
TH_3201|M.thermoresistible__bu GNKPLRTKWGGKIYGSGLPSDIWKATMDGALKGTERESFPKPGEIGGYAG
Rv0050|M.tuberculosis_H37Rv GDEPLVTASGAAIYGSGLPSDIWKATMDGALKGTSNETFPKPTEVGGYAG
Mb0051|M.bovis_AF2122/97 GDEPLVTASGAAIYGSGLPSDIWKATMDGALKGTSNETFPKPTEVGGYAG
MMAR_0069|M.marinum_M GDEPLVTASGAPIYGSGLPSDIWKATMDGALKGTEVESFPKPTEIGGYAG
MUL_0068|M.ulcerans_Agy99 GDEPLVTASGAPIYGSGLPSDIWKATMDGALKGTEVESFPKPTEIGGYAG
MAV_0071|M.avium_104 GDQPLVTASGGPVYGSGLPSDIWKATMDGALKGTPNESFPKPAEVGGYAG
MLBr_02688|M.leprae_Br4923 DNVPLITASGEAIYGSGLPSDIWKSTMDGALEGTPNEGFPKPTEVGGYAG
MAB_4901c|M.abscessus_ATCC_199 G-KPIKTSWGGPIYGSGLPSDIWKKTMDGALDGTAKETFPKPGPIGGYAG
. *: . * :******.:*** ***.**.** * **** :*****
Mflv_0871|M.gilvum_PYR-GCK VPQ-APPPPPSS-----TAPPTPSETVIQPTLEIAPGITIPWG-------
Mvan_6036|M.vanbaalenii_PYR-1 VPQ-APPPPPSPS---VTVPPPPSETVIQPTLEIAPGITIPWG-------
MSMEG_6900|M.smegmatis_MC2_155 VPQ-APAAPPPSAGP-PTDPGQPSVTVIQPTIEVAPGITIPIG-------
TH_3201|M.thermoresistible__bu VPQ-APSPQRTSDDDGTTTVTPPSETVIQPSVEVAPGITIPLGXAVSAVV
Rv0050|M.tuberculosis_H37Rv VPP-PPPPP--EV--------PPSETVIQPTVEIAPGITIPIG-------
Mb0051|M.bovis_AF2122/97 VPP-PPPPPPSEV--------PPSETVIQPTVEIAPGITIPIG-------
MMAR_0069|M.marinum_M VPA-PPPPPPEAP--------PPSETVIQPTVEIAPGITIPVG-------
MUL_0068|M.ulcerans_Agy99 VPA-PPPPPPEAP--------PPAETVIQPTVEIVPGITIPVG-------
MAV_0071|M.avium_104 VPA-PPPPP--KA--------PPSETVIQPTIEVAPGITIPVG-------
MLBr_02688|M.leprae_Br4923 VPT-LAPPP-------------PLKKVIQPTIEVAPGIIIPVG-------
MAB_4901c|M.abscessus_ATCC_199 VPTYVPPPPVPNGPPAPAPTGGGEVTVIQPTIEIAPGITIPVG-------
** ... .****::*:.*** ** *
Mflv_0871|M.gilvum_PYR-GCK --------------PPTT--------------------------------
Mvan_6036|M.vanbaalenii_PYR-1 --------------PPTT--------------------------------
MSMEG_6900|M.smegmatis_MC2_155 --------------PPTT--------------------------------
TH_3201|M.thermoresistible__bu RVRDAVVRPHLVAEPPLTGRPDGTSRPGRRAPVRRCRNVDFRRDIGAPCA
Rv0050|M.tuberculosis_H37Rv --------------PPTT--------------------------------
Mb0051|M.bovis_AF2122/97 --------------PPTT--------------------------------
MMAR_0069|M.marinum_M --------------PPTT--------------------------------
MUL_0068|M.ulcerans_Agy99 --------------PPTT--------------------------------
MAV_0071|M.avium_104 --------------PPTT--------------------------------
MLBr_02688|M.leprae_Br4923 --------------PPTT--------------------------------
MAB_4901c|M.abscessus_ATCC_199 --------------PPTT--------------------------------
** *
Mflv_0871|M.gilvum_PYR-GCK --------------------------------------------VPVGP-
Mvan_6036|M.vanbaalenii_PYR-1 --------------------------------------------VPVAPP
MSMEG_6900|M.smegmatis_MC2_155 --------------------------------------------VPVGPP
TH_3201|M.thermoresistible__bu FHRDRRWLPADAVRAEPLGRGSPQRTGPGRAGGLLSGAAVRGTGVPSEPA
Rv0050|M.tuberculosis_H37Rv --------------------------------------------ITLAP-
Mb0051|M.bovis_AF2122/97 --------------------------------------------ITLAP-
MMAR_0069|M.marinum_M --------------------------------------------ITLAP-
MUL_0068|M.ulcerans_Agy99 --------------------------------------------ITLAP-
MAV_0071|M.avium_104 --------------------------------------------VTLAP-
MLBr_02688|M.leprae_Br4923 --------------------------------------------VTVPP-
MAB_4901c|M.abscessus_ATCC_199 --------------------------------------------VPVGP-
:. *
Mflv_0871|M.gilvum_PYR-GCK -PGAPP--VPETAPPVPPPGAPVPPGAPPPPGA-------PVPPGAPPGP
Mvan_6036|M.vanbaalenii_PYR-1 VPGAPP--APGAPPPAGAPGAPVPPGAPPP------------------GP
MSMEG_6900|M.smegmatis_MC2_155 -PGAPG--APVGP---GAPEVPVAPGAPGVP-----------------GA
TH_3201|M.thermoresistible__bu HGGSVPRRAGGADDGADAPGAGRAPGAQRRVR--------HHPGGPDGGP
Rv0050|M.tuberculosis_H37Rv -----------------PPP--APP---------------------AATP
Mb0051|M.bovis_AF2122/97 -----------------PPP--APP---------------------AATP
MMAR_0069|M.marinum_M -----------------PPPPGAPP-----------------------AD
MUL_0068|M.ulcerans_Agy99 -----------------PPPPGAPP-----------------------AD
MAV_0071|M.avium_104 -----------------APPAGGPPGGPEPGGGVPPGPGGGVPPGGPQAP
MLBr_02688|M.leprae_Br4923 -----------------TQALPDLT-----------------------TS
MAB_4901c|M.abscessus_ATCC_199 ----------------AAPPAGDVP------------------------P
. .
Mflv_0871|M.gilvum_PYR-GCK LPPP----------
Mvan_6036|M.vanbaalenii_PYR-1 LPPP----------
MSMEG_6900|M.smegmatis_MC2_155 PPPP----------
TH_3201|M.thermoresistible__bu RQPAAVSPLRGTTR
Rv0050|M.tuberculosis_H37Rv TPPP----------
Mb0051|M.bovis_AF2122/97 TPPP----------
MMAR_0069|M.marinum_M NPPP----------
MUL_0068|M.ulcerans_Agy99 NPPP----------
MAV_0071|M.avium_104 PPPP----------
MLBr_02688|M.leprae_Br4923 TTPP----------
MAB_4901c|M.abscessus_ATCC_199 PGP-----------
*