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MARPIRIGVTLQPANAPDYATWRSAVIHAEELGADLVFGWDHFHRPEMAELNQGVPVLAEVQPDVTNFEG WTALASWGEITHRAQIGLLVTGMGYRNPDLLADMARTVDHISGGRLVLGLGAGWYEKDYTTYGYEFGTWK TRFDLFEAGLERITARFDKLIPTPVRTIPILIGGTGPKRTLPLVVRYADIWHTFLSVEGFTEATARLDEM AAAAGRDGNDIERSVHWFGVDSAEDYRAAGATIFVHEIAPDPATGYDFTTLEEMLAWRDHHNGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6885 | - | - | 100% (274) | MmcI protein |
| M. smegmatis MC2 155 | MSMEG_2906 | - | 5e-96 | 62.88% (264) | hypothetical protein MSMEG_2906 |
| M. smegmatis MC2 155 | MSMEG_6907 | - | 2e-58 | 46.32% (272) | MmcI protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0045c | - | 2e-60 | 46.67% (270) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0860 | - | 3e-61 | 45.49% (277) | hypothetical protein Mflv_0860 |
| M. tuberculosis H37Rv | Rv0044c | - | 2e-60 | 46.67% (270) | oxidoreductase |
| M. leprae Br4923 | MLBr_00131 | - | 8e-12 | 27.97% (236) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3016c | - | 3e-87 | 58.67% (271) | hypothetical protein MAB_3016c |
| M. marinum M | MMAR_0628 | - | 2e-82 | 56.06% (264) | monooxygenase |
| M. avium 104 | MAV_0061 | - | 7e-61 | 47.45% (274) | MmcI protein |
| M. thermoresistible (build 8) | TH_0517 | - | 1e-59 | 47.41% (270) | MmcI protein |
| M. ulcerans Agy99 | MUL_0062 | - | 2e-61 | 47.58% (269) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2936 | - | 1e-100 | 62.22% (270) | hypothetical protein Mvan_2936 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6885|M.smegmatis_MC2_155 MAR------PIRIGVTLQPANAPDYATWRSAVIHAEELGADLVFGWDHFH
Mvan_2936|M.vanbaalenii_PYR-1 MTR------SVRVAVQIQPGGAPDYRSWRDAVLAADDLGVDVIFGYDHFH
MMAR_0628|M.marinum_M MTNN----AAPRIGVHIWPGGAPDYATWRQAVLDAESLGADAIFGYDHFH
MAB_3016c|M.abscessus_ATCC_199 MTD------RIRIGIQLRPAKTQSYKQWRDAVLRAEDKGADVIFGYDHFH
Mb0045c|M.bovis_AF2122/97 MTSLVRPDLPVRIGVQLQPQHAPHYRAVRDAVRRCEDIGVDIAFTWDHFF
Rv0044c|M.tuberculosis_H37Rv MTSLVRPDLPVRIGVQLQPQHAPHYRAVRDAVRRCEDIGVDIAFTWDHFF
MUL_0062|M.ulcerans_Agy99 MTSPVHPDRPLRIGVQLQPQHASHYGDIRDAVRRCEDIGVDIAFNWDHFF
MAV_0061|M.avium_104 MT------HPIRIGVQLQPQHAPQYNQIRDAVRRCEDIGVDIAFNWDHFF
Mflv_0860|M.gilvum_PYR-GCK MTS--ETSRPIRIGVQLQPQHSPRYDLMRDAVRRCEDIGVDVVFNWDHFF
TH_0517|M.thermoresistible__bu --------------VQLQPQHSPDYGNLRDAVRRAEDIGVDIAFNWDHFF
MLBr_00131|M.leprae_Br4923 MAG-----FRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLN
: * :: *.* : **:
MSMEG_6885|M.smegmatis_MC2_155 RPE---MAELNQGVPVLAEVQPDVTNFEGWTALA--SWGEITHRAQIGLL
Mvan_2936|M.vanbaalenii_PYR-1 RPA---MEAIVDGKPVLSDEQPDVANFEGWTALA--SWGEITSNADIGLL
MMAR_0628|M.marinum_M KP----FVEIVDGGPRLLPDQPDVNNFEAWTALA--SWGEITSRPDIGLL
MAB_3016c|M.abscessus_ATCC_199 WP----AGTLSSQGVVLDEVQPDVNNFEGWTALG--SWAEVTSRAEIGLL
Mb0045c|M.bovis_AF2122/97 PL----------------YGDPDGPHFECWTVLG--AWAEQTSHIEIGAL
Rv0044c|M.tuberculosis_H37Rv PL----------------YGDPDGPHFECWTVLG--AWAEQTSHIEIGAL
MUL_0062|M.ulcerans_Agy99 PL----------------FGDPDGAHFECWTMLA--AWAEQTSRIQIGAL
MAV_0061|M.avium_104 PL----------------YGDPDGAHFECWTMLG--AWAEQTSRIQIGAL
Mflv_0860|M.gilvum_PYR-GCK PL----------------YGDPDGAHFECWTMLG--AWAEQTSRVEIGAL
TH_0517|M.thermoresistible__bu PL----------------YGDPDGAHFECWTMLG--AWAEQTSRIEIGAL
MLBr_00131|M.leprae_Br4923 ALVPRSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVC
::* ** *. : .: :*
MSMEG_6885|M.smegmatis_MC2_155 VTGMGYRNPDLLADMARTVDHISGGRLVLGLGAGWYEKDYTTYGYEFGTW
Mvan_2936|M.vanbaalenii_PYR-1 VTGVGYRNADLLADMARTVDHISGGRLILGLGAGWYEKDYTTYGYDFGTF
MMAR_0628|M.marinum_M VTGIGFRNPDLLADMARTVDHISGGRLILGIGSGWYEKDYLAYGYDYPSI
MAB_3016c|M.abscessus_ATCC_199 VTGVGYRNPDLLADMARTVDHISGGRLILGVGAGWYERDYTTYGYDFGTT
Mb0045c|M.bovis_AF2122/97 VTCNSYRNPELLADMARTVDHISGGRLILGIGSGWKQKDYDEYGYRFGTA
Rv0044c|M.tuberculosis_H37Rv VTCNSYRNPELLADMARTVDHISGGRLILGIGSGWKQKDYDEYGYRFGTA
MUL_0062|M.ulcerans_Agy99 VTCNSYRNPELLADMARTVDHICDGRLILGIGSGWKQKDYDEYGYEFGTA
MAV_0061|M.avium_104 VTCNSYRNPELLADMARTVDHISEGRLILGIGSGWKQKDYDEYGYEFGTA
Mflv_0860|M.gilvum_PYR-GCK VTCNSYRNPELLADMARTVDHISDGRLILGIGSGWKQKDYDEYGYEFGTV
TH_0517|M.thermoresistible__bu VTCNSYRNPDLLADMARTVDHISGGRLIFGIGSGWFRRDYDEYGYEFGTA
MLBr_00131|M.leprae_Br4923 VTDAGRRNPAVTAQAAATLHLLTRGKAMLGIGVGERE-GNEPYGVEWTKP
** . **. : *: * *:. : *: ::*:* * . . ** : .
MSMEG_6885|M.smegmatis_MC2_155 KTRFDLFEAGLERITARFDKLI----------------PTPVRTIPILIG
Mvan_2936|M.vanbaalenii_PYR-1 GSRFDLFDESLIRIENRLAALI----------------PPPVRKLPILIG
MMAR_0628|M.marinum_M GERMQQLADGLHRIKRRFRQLL----------------PPPIREIPLLLG
MAB_3016c|M.abscessus_ATCC_199 GSRFDLFEDSLVRIESRLGQLL----------------PQPVRPIPILIG
Mb0045c|M.bovis_AF2122/97 GSRLDDLAAALPRIKARLGKLN----------------PPPTRDIPVLIG
Rv0044c|M.tuberculosis_H37Rv GSRLDDLAAALPRIKARLGKLN----------------PPPTRDIPVLIG
MUL_0062|M.ulcerans_Agy99 GSRLDDLAGALPRIKTRLAKLI----------------PAPTRDIPVLIG
MAV_0061|M.avium_104 GSRLDDLAGALPRIEARLAKLN----------------PAPTRDIPVLIG
Mflv_0860|M.gilvum_PYR-GCK GSRLDDLAAALPRIESRLSKLN----------------PQPVRDIPVLIG
TH_0517|M.thermoresistible__bu GGRLDDLAAALPRIKARWAKLN----------------PPPTRELPILIG
MLBr_00131|M.leprae_Br4923 VARFQEALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPEIWV
*:: : : * * * :
MSMEG_6885|M.smegmatis_MC2_155 GTGPKRTLPLVVRYADIWHTFLSV--EGFTEATARLDEMAAAAGRDGNDI
Mvan_2936|M.vanbaalenii_PYR-1 GTGPKRSLPAVARHADIWHAFQDL--DAFRRSSDRVDELAATFGRNGADI
MMAR_0628|M.marinum_M GSGERKTLPLVGQYADIWHSYEPL--EEFRRKNDLVRRHADAAQRDEAKI
MAB_3016c|M.abscessus_ATCC_199 GGGEKRTIPLVARHAHIWHAFGDI--DTYRRKNSVLIAEADRIGRDHNEI
Mb0045c|M.bovis_AF2122/97 GGGERKTLRLVAEYADIWHSFTAG--DSYLAKSAVLSTHCSTVGRNPATI
Rv0044c|M.tuberculosis_H37Rv GGGERKTLRLVAEYADIWHSFTAG--DSYLAKSAVLSTHCSTVGRNPATI
MUL_0062|M.ulcerans_Agy99 GGGERKTLRLVAEHADIWHSFTGV--DEFPAKSAVLARHCADVGRDPATI
MAV_0061|M.avium_104 GGGERKTLRLVAQHADIWHSFTSA--EEYPAKSEVLARHCADVGRDPDRI
Mflv_0860|M.gilvum_PYR-GCK GGGERKTLRMVAQHAHIWHSFSDT--ETYPRKSEILARHCADVGRDPDAI
TH_0517|M.thermoresistible__bu GMGEKKTLRLVAEHAHIWHGFVDR--STYPHKSRVLAEHCAAVGRDPDTI
MLBr_00131|M.leprae_Br4923 AAHGPRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSI
. : : . .:*. * : : . *: *
MSMEG_6885|M.smegmatis_MC2_155 ERSVHW-------FGVDSAEDYRAAGATIFVHEIAPDPAT--------GY
Mvan_2936|M.vanbaalenii_PYR-1 ERSTLW-------QNAHSADAFREAGVTLFQTELTSD--D--------GY
MMAR_0628|M.marinum_M ERAMAW-------TTPADADAYHREGVSLLTTEIQPT-TD--------GY
MAB_3016c|M.abscessus_ATCC_199 ERSTSWGLDPERGLTAAEADAYVEVGARLFTVGIDAD--N--------GY
Mb0045c|M.bovis_AF2122/97 ERSAAV----DGGGLIASAEALAGLGVTLLTVGCDGP-----------DY
Rv0044c|M.tuberculosis_H37Rv ERSAAV----DGGGLIASAEALAGLGVTLLTVGCDGP-----------DY
MUL_0062|M.ulcerans_Agy99 ERSAALQ---DSGRLSADADALAGLGVTLLTVGCDGP-----------DY
MAV_0061|M.avium_104 ERSAAVK---GGAELLANAEALVGLGVTLLTVGCDGP-----------DY
Mflv_0860|M.gilvum_PYR-GCK ERSAEAKGR-TEDALLENAAALTSLGVSMLTVGVNGP-----------DY
TH_0517|M.thermoresistible__bu ERSSGLPVEGGVDAALAEAAALVEQGVTLLTVGVNGP-----------DY
MLBr_00131|M.leprae_Br4923 TPAAVRG-IITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGA
: . :: .
MSMEG_6885|M.smegmatis_MC2_155 DFT--------------------------------------TLEEMLAWR
Mvan_2936|M.vanbaalenii_PYR-1 DLA--------------------------------------PLKQVLTWR
MMAR_0628|M.marinum_M DLG--------------------------------------ILGEMIAWR
MAB_3016c|M.abscessus_ATCC_199 DLS--------------------------------------VLDAPLAWR
Mb0045c|M.bovis_AF2122/97 DLS--------------------------------------AAAALCRWR
Rv0044c|M.tuberculosis_H37Rv DLS--------------------------------------AAAALCRWR
MUL_0062|M.ulcerans_Agy99 DLA--------------------------------------AAEALCRWR
MAV_0061|M.avium_104 DLR--------------------------------------DAQALCKWR
Mflv_0860|M.gilvum_PYR-GCK DLS--------------------------------------QAETLCRWR
TH_0517|M.thermoresistible__bu DLS--------------------------------------IAEALCRWR
MLBr_00131|M.leprae_Br4923 DFAGVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWR
*: **
MSMEG_6885|M.smegmatis_MC2_155 DHHNGG---------------------------------
Mvan_2936|M.vanbaalenii_PYR-1 D--NG----------------------------------
MMAR_0628|M.marinum_M DGRSR----------------------------------
MAB_3016c|M.abscessus_ATCC_199 DSRS-----------------------------------
Mb0045c|M.bovis_AF2122/97 DGR------------------------------------
Rv0044c|M.tuberculosis_H37Rv DGR------------------------------------
MUL_0062|M.ulcerans_Agy99 DSR------------------------------------
MAV_0061|M.avium_104 DGR------------------------------------
Mflv_0860|M.gilvum_PYR-GCK DSHTAAG--------------------------------
TH_0517|M.thermoresistible__bu DNR------------------------------------
MLBr_00131|M.leprae_Br4923 DHGLKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL
*