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TNNAAPRIGVHIWPGGAPDYATWRQAVLDAESLGADAIFGYDHFHKPFVEIVDGGPRLLPDQPDVNNFEA WTALASWGEITSRPDIGLLVTGIGFRNPDLLADMARTVDHISGGRLILGIGSGWYEKDYLAYGYDYPSIG ERMQQLADGLHRIKRRFRQLLPPPIREIPLLLGGSGERKTLPLVGQYADIWHSYEPLEEFRRKNDLVRRH ADAAQRDEAKIERAMAWTTPADADAYHREGVSLLTTEIQPTTDGYDLGILGEMIAWRDGRSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0628 | - | - | 100% (273) | monooxygenase |
| M. marinum M | MMAR_0063 | - | 9e-61 | 48.52% (270) | oxidoreductase |
| M. marinum M | MMAR_4673 | - | 5e-29 | 31.33% (249) | hypothetical protein MMAR_4673 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0045c | - | 3e-60 | 47.96% (269) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0860 | - | 5e-59 | 45.76% (271) | hypothetical protein Mflv_0860 |
| M. tuberculosis H37Rv | Rv0044c | - | 3e-60 | 47.96% (269) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 2e-10 | 29.53% (149) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3016c | - | 3e-83 | 54.41% (272) | hypothetical protein MAB_3016c |
| M. avium 104 | MAV_0061 | - | 3e-60 | 47.74% (266) | MmcI protein |
| M. smegmatis MC2 155 | MSMEG_2906 | - | 1e-102 | 63.67% (267) | hypothetical protein MSMEG_2906 |
| M. thermoresistible (build 8) | TH_0517 | - | 7e-59 | 45.15% (268) | MmcI protein |
| M. ulcerans Agy99 | MUL_0062 | - | 2e-61 | 48.52% (270) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2936 | - | 7e-89 | 57.79% (263) | hypothetical protein Mvan_2936 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0628|M.marinum_M -----MTNN----AAPRIGVHIWPGGAPDYATWRQAVLDAESLGADAIFG
MSMEG_2906|M.smegmatis_MC2_155 --MTTQTNS----NSIRIGVQLWPGGVADYRTWRDAVLRAEELGVDVIFG
Mvan_2936|M.vanbaalenii_PYR-1 -----MTR------SVRVAVQIQPGGAPDYRSWRDAVLAADDLGVDVIFG
MAB_3016c|M.abscessus_ATCC_199 -----MTD------RIRIGIQLRPAKTQSYKQWRDAVLRAEDKGADVIFG
Mb0045c|M.bovis_AF2122/97 -----MTSLVRPDLPVRIGVQLQPQHAPHYRAVRDAVRRCEDIGVDIAFT
Rv0044c|M.tuberculosis_H37Rv -----MTSLVRPDLPVRIGVQLQPQHAPHYRAVRDAVRRCEDIGVDIAFT
MUL_0062|M.ulcerans_Agy99 -----MTSPVHPDRPLRIGVQLQPQHASHYGDIRDAVRRCEDIGVDIAFN
MAV_0061|M.avium_104 -----MT------HPIRIGVQLQPQHAPQYNQIRDAVRRCEDIGVDIAFN
Mflv_0860|M.gilvum_PYR-GCK -----MTS--ETSRPIRIGVQLQPQHSPRYDLMRDAVRRCEDIGVDVVFN
TH_0517|M.thermoresistible__bu -------------------VQLQPQHSPDYGNLRDAVRRAEDIGVDIAFN
MLBr_00348|M.leprae_Br4923 MVER--------ANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFT
::: : * .: * * *
MMAR_0628|M.marinum_M YDHFHKPFVE-IVDGGPRLLPDQPDVNNFEAWTALASWGEITSRPDIGLL
MSMEG_2906|M.smegmatis_MC2_155 YDHFHRPTAE-IVDGGPRLLPDQPAVNNFEGWTALASWGEITTRTEIGLL
Mvan_2936|M.vanbaalenii_PYR-1 YDHFHRPAMEAIVDGKPVLSDEQPDVANFEGWTALASWGEITSNADIGLL
MAB_3016c|M.abscessus_ATCC_199 YDHFHWPAGT-LSSQGVVLDEVQPDVNNFEGWTALGSWAEVTSRAEIGLL
Mb0045c|M.bovis_AF2122/97 WDHFFPLYGD-------------PDGPHFECWTVLGAWAEQTSHIEIGAL
Rv0044c|M.tuberculosis_H37Rv WDHFFPLYGD-------------PDGPHFECWTVLGAWAEQTSHIEIGAL
MUL_0062|M.ulcerans_Agy99 WDHFFPLFGD-------------PDGAHFECWTMLAAWAEQTSRIQIGAL
MAV_0061|M.avium_104 WDHFFPLYGD-------------PDGAHFECWTMLGAWAEQTSRIQIGAL
Mflv_0860|M.gilvum_PYR-GCK WDHFFPLYGD-------------PDGAHFECWTMLGAWAEQTSRVEIGAL
TH_0517|M.thermoresistible__bu WDHFFPLYGD-------------PDGAHFECWTMLGAWAEQTSRIEIGAL
MLBr_00348|M.leprae_Br4923 GEAWG-----------------------SDAYTPLAWWGSSTQRVRLGTS
: : : :* *. *.. * . :*
MMAR_0628|M.marinum_M VTGIGFRNPDLLADMARTVDHISGGRLILGIGSGWYEKDYLAYGYDYPSI
MSMEG_2906|M.smegmatis_MC2_155 VTGIGYRNPDLLADMARTVDHISGGRLILGLGSGWYEKDYHDYGYEYGSV
Mvan_2936|M.vanbaalenii_PYR-1 VTGVGYRNADLLADMARTVDHISGGRLILGLGAGWYEKDYTTYGYDFGTF
MAB_3016c|M.abscessus_ATCC_199 VTGVGYRNPDLLADMARTVDHISGGRLILGVGAGWYERDYTTYGYDFGTT
Mb0045c|M.bovis_AF2122/97 VTCNSYRNPELLADMARTVDHISGGRLILGIGSGWKQKDYDEYGYRFGTA
Rv0044c|M.tuberculosis_H37Rv VTCNSYRNPELLADMARTVDHISGGRLILGIGSGWKQKDYDEYGYRFGTA
MUL_0062|M.ulcerans_Agy99 VTCNSYRNPELLADMARTVDHICDGRLILGIGSGWKQKDYDEYGYEFGTA
MAV_0061|M.avium_104 VTCNSYRNPELLADMARTVDHISEGRLILGIGSGWKQKDYDEYGYEFGTA
Mflv_0860|M.gilvum_PYR-GCK VTCNSYRNPELLADMARTVDHISDGRLILGIGSGWKQKDYDEYGYEFGTV
TH_0517|M.thermoresistible__bu VTCNSYRNPDLLADMARTVDHISGGRLIFGIGSGWFRRDYDEYGYEFGTA
MLBr_00348|M.leprae_Br4923 VVQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKP
*. . *.. * * *:**:. ** *:*:* . . ** : .
MMAR_0628|M.marinum_M GERMQQLADGLHRIKRRFRQLL------PPPIR-----------------
MSMEG_2906|M.smegmatis_MC2_155 ASRMDLFEAGLARIEQRLDRLV------PAPLR-----------------
Mvan_2936|M.vanbaalenii_PYR-1 GSRFDLFDESLIRIENRLAALI------PPPVR-----------------
MAB_3016c|M.abscessus_ATCC_199 GSRFDLFEDSLVRIESRLGQLL------PQPVR-----------------
Mb0045c|M.bovis_AF2122/97 GSRLDDLAAALPRIKARLGKLN------PPPTR-----------------
Rv0044c|M.tuberculosis_H37Rv GSRLDDLAAALPRIKARLGKLN------PPPTR-----------------
MUL_0062|M.ulcerans_Agy99 GSRLDDLAGALPRIKTRLAKLI------PAPTR-----------------
MAV_0061|M.avium_104 GSRLDDLAGALPRIEARLAKLN------PAPTR-----------------
Mflv_0860|M.gilvum_PYR-GCK GSRLDDLAAALPRIESRLSKLN------PQPVR-----------------
TH_0517|M.thermoresistible__bu GGRLDDLAAALPRIKARWAKLN------PPPTR-----------------
MLBr_00348|M.leprae_Br4923 LSRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPITHP
* : :: * : * *
MMAR_0628|M.marinum_M ---EIPLLLGGSGER------------KTLPLVGQYADIWHSYEPL----
MSMEG_2906|M.smegmatis_MC2_155 ---HIPILIGGAGER------------RTMPLVARHADIWHSFLDI----
Mvan_2936|M.vanbaalenii_PYR-1 ---KLPILIGGTGPK------------RSLPAVARHADIWHAFQDL----
MAB_3016c|M.abscessus_ATCC_199 ---PIPILIGGGGEK------------RTIPLVARHAHIWHAFGDI----
Mb0045c|M.bovis_AF2122/97 ---DIPVLIGGGGER------------KTLRLVAEYADIWHSFTAG----
Rv0044c|M.tuberculosis_H37Rv ---DIPVLIGGGGER------------KTLRLVAEYADIWHSFTAG----
MUL_0062|M.ulcerans_Agy99 ---DIPVLIGGGGER------------KTLRLVAEHADIWHSFTGV----
MAV_0061|M.avium_104 ---DIPVLIGGGGER------------KTLRLVAQHADIWHSFTSA----
Mflv_0860|M.gilvum_PYR-GCK ---DIPVLIGGGGER------------KTLRMVAQHAHIWHSFSDT----
TH_0517|M.thermoresistible__bu ---ELPILIGGMGEK------------KTLRLVAEHAHIWHGFVDR----
MLBr_00348|M.leprae_Br4923 LRADIPIMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFAR
:*:::*. * : .: . *.::: :
MMAR_0628|M.marinum_M -------------------------EEFRRKNDLVRRHADAAQRD----E
MSMEG_2906|M.smegmatis_MC2_155 -------------------------ESFRKKSQLLEQLADGVDRD----H
Mvan_2936|M.vanbaalenii_PYR-1 -------------------------DAFRRSSDRVDELAATFGRN----G
MAB_3016c|M.abscessus_ATCC_199 -------------------------DTYRRKNSVLIAEADRIGRD----H
Mb0045c|M.bovis_AF2122/97 -------------------------DSYLAKSAVLSTHCSTVGRN----P
Rv0044c|M.tuberculosis_H37Rv -------------------------DSYLAKSAVLSTHCSTVGRN----P
MUL_0062|M.ulcerans_Agy99 -------------------------DEFPAKSAVLARHCADVGRD----P
MAV_0061|M.avium_104 -------------------------EEYPAKSEVLARHCADVGRD----P
Mflv_0860|M.gilvum_PYR-GCK -------------------------ETYPRKSEILARHCADVGRD----P
TH_0517|M.thermoresistible__bu -------------------------STYPHKSRVLAEHCAAVGRD----P
MLBr_00348|M.leprae_Br4923 TGARRSREDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFH
: . : :
MMAR_0628|M.marinum_M AKIERAMAW-------TTPADADAYHREGVSLLTTEIQPTTDGYDLG-IL
MSMEG_2906|M.smegmatis_MC2_155 RKIDRAVQW-------TGADEAGEYVAEGVTLFTAVIRPDTNGYEFT-EV
Mvan_2936|M.vanbaalenii_PYR-1 ADIERSTLW-------QNAHSADAFREAGVTLFQTELTSD-DGYDLA-PL
MAB_3016c|M.abscessus_ATCC_199 NEIERSTSWGLDPERGLTAAEADAYVEVGARLFTVGIDAD-NGYDLS-VL
Mb0045c|M.bovis_AF2122/97 ATIERSAAV----DGGGLIASAEALAGLGVTLLTVGCDGP--DYDLS-AA
Rv0044c|M.tuberculosis_H37Rv ATIERSAAV----DGGGLIASAEALAGLGVTLLTVGCDGP--DYDLS-AA
MUL_0062|M.ulcerans_Agy99 ATIERSAALQ---DSGRLSADADALAGLGVTLLTVGCDGP--DYDLA-AA
MAV_0061|M.avium_104 DRIERSAAVK---GGAELLANAEALVGLGVTLLTVGCDGP--DYDLR-DA
Mflv_0860|M.gilvum_PYR-GCK DAIERSAEAKGR-TEDALLENAAALTSLGVSMLTVGVNGP--DYDLS-QA
TH_0517|M.thermoresistible__bu DTIERSSGLPVEGGVDAALAEAAALVEQGVTLLTVGVNGP--DYDLS-IA
MLBr_00348|M.leprae_Br4923 ADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVC
: * : . : :.
MMAR_0628|M.marinum_M GEMIAWRDGRSR-------------------
MSMEG_2906|M.smegmatis_MC2_155 ESMLAWR--RAQ-------------------
Mvan_2936|M.vanbaalenii_PYR-1 KQVLTWRDNG---------------------
MAB_3016c|M.abscessus_ATCC_199 DAPLAWRDSRS--------------------
Mb0045c|M.bovis_AF2122/97 AALCRWRDGR---------------------
Rv0044c|M.tuberculosis_H37Rv AALCRWRDGR---------------------
MUL_0062|M.ulcerans_Agy99 EALCRWRDSR---------------------
MAV_0061|M.avium_104 QALCKWRDGR---------------------
Mflv_0860|M.gilvum_PYR-GCK ETLCRWRDSHTAAG-----------------
TH_0517|M.thermoresistible__bu EALCRWRDNR---------------------
MLBr_00348|M.leprae_Br4923 KQIAAWSAAGVTMMMVSASSVEQVRDLAGLF
*