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TSLVRPDLPVRIGVQLQPQHAPHYRAVRDAVRRCEDIGVDIAFTWDHFFPLYGDPDGPHFECWTVLGAWA EQTSHIEIGALVTCNSYRNPELLADMARTVDHISGGRLILGIGSGWKQKDYDEYGYRFGTAGSRLDDLAA ALPRIKARLGKLNPPPTRDIPVLIGGGGERKTLRLVAEYADIWHSFTAGDSYLAKSAVLSTHCSTVGRNP ATIERSAAVDGGGLIASAEALAGLGVTLLTVGCDGPDYDLSAAAALCRWRDGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0044c | - | - | 100% (264) | POSSIBLE OXIDOREDUCTASE |
| M. tuberculosis H37Rv | Rv1855c | - | 3e-34 | 39.41% (203) | oxidoreductase |
| M. tuberculosis H37Rv | Rv0791c | - | 4e-21 | 34.25% (181) | hypothetical protein Rv0791c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0045c | - | 1e-157 | 100.00% (264) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0860 | - | 1e-116 | 75.78% (256) | hypothetical protein Mflv_0860 |
| M. leprae Br4923 | MLBr_00348 | - | 5e-11 | 29.00% (200) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3016c | - | 3e-68 | 50.55% (271) | hypothetical protein MAB_3016c |
| M. marinum M | MMAR_0063 | - | 1e-130 | 83.77% (265) | oxidoreductase |
| M. avium 104 | MAV_0061 | - | 1e-128 | 83.98% (256) | MmcI protein |
| M. smegmatis MC2 155 | MSMEG_6907 | - | 1e-118 | 79.13% (254) | MmcI protein |
| M. thermoresistible (build 8) | TH_0517 | - | 1e-112 | 75.98% (254) | MmcI protein |
| M. ulcerans Agy99 | MUL_0062 | - | 1e-129 | 83.40% (265) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_6045 | - | 1e-117 | 75.97% (258) | hypothetical protein Mvan_6045 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0044c|M.tuberculosis_H37Rv MTSLVRPDLPVRIGVQLQPQHAPHYRAVRDAVRRCEDIGVDIAFTWDHFF
Mb0045c|M.bovis_AF2122/97 MTSLVRPDLPVRIGVQLQPQHAPHYRAVRDAVRRCEDIGVDIAFTWDHFF
MMAR_0063|M.marinum_M MTSPVHPDRPLRIGVQLQPQHASHYGDIRDAVRRCEDIGVDIAFNWDHFF
MUL_0062|M.ulcerans_Agy99 MTSPVHPDRPLRIGVQLQPQHASHYGDIRDAVRRCEDIGVDIAFNWDHFF
MAV_0061|M.avium_104 MT------HPIRIGVQLQPQHAPQYNQIRDAVRRCEDIGVDIAFNWDHFF
Mflv_0860|M.gilvum_PYR-GCK MTS--ETSRPIRIGVQLQPQHSPRYDLMRDAVRRCEDIGVDVVFNWDHFF
Mvan_6045|M.vanbaalenii_PYR-1 ------MTFPIRIGVQLQPQHSPRYGHLRDAVRRCEDLGVDVAFNWDHFF
MSMEG_6907|M.smegmatis_MC2_155 --------------MQLQPQHSPEYRFIRDAVRRCEDIGVDIAFNWDHFF
TH_0517|M.thermoresistible__bu --------------VQLQPQHSPDYGNLRDAVRRAEDIGVDIAFNWDHFF
MAB_3016c|M.abscessus_ATCC_199 ------MTDRIRIGIQLRPAKTQSYKQWRDAVLRAEDKGADVIFGYDHFH
MLBr_00348|M.leprae_Br4923 ---MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWG
:** : : * .*. * * * : :
Rv0044c|M.tuberculosis_H37Rv PLYG------------DPDGPHFECWTVLGAWAEQTSHIEIGALVTCNSY
Mb0045c|M.bovis_AF2122/97 PLYG------------DPDGPHFECWTVLGAWAEQTSHIEIGALVTCNSY
MMAR_0063|M.marinum_M PLFG------------DPDGAHFECWTMLAAWAEQTSRIQIGALVTCNSY
MUL_0062|M.ulcerans_Agy99 PLFG------------DPDGAHFECWTMLAAWAEQTSRIQIGALVTCNSY
MAV_0061|M.avium_104 PLYG------------DPDGAHFECWTMLGAWAEQTSRIQIGALVTCNSY
Mflv_0860|M.gilvum_PYR-GCK PLYG------------DPDGAHFECWTMLGAWAEQTSRVEIGALVTCNSY
Mvan_6045|M.vanbaalenii_PYR-1 PLYG------------DPDGAHFECWTMLGAWAEQTSRIEIGALVSCNSY
MSMEG_6907|M.smegmatis_MC2_155 PLYG------------DPDGAHYECWTMLGAWAEQTSRIEIGALVTCNSY
TH_0517|M.thermoresistible__bu PLYG------------DPDGAHFECWTMLGAWAEQTSRIEIGALVTCNSY
MAB_3016c|M.abscessus_ATCC_199 WPAGTLSSQGVVLDEVQPDVNNFEGWTALGSWAEVTSRAEIGLLVTGVGY
MLBr_00348|M.leprae_Br4923 ----------------------SDAYTPLAWWGSSTQRVRLGTSVVQLSA
: :* *. *.. *.: .:* * .
Rv0044c|M.tuberculosis_H37Rv RNPELLADMARTVDHISGGRLILGIGSGWKQKDYDEYGYRFGTAGSRLDD
Mb0045c|M.bovis_AF2122/97 RNPELLADMARTVDHISGGRLILGIGSGWKQKDYDEYGYRFGTAGSRLDD
MMAR_0063|M.marinum_M RNPELLADMARTVDHICDGRLILGIGSGWKQKDYDEYGYEFGTAGSRLDD
MUL_0062|M.ulcerans_Agy99 RNPELLADMARTVDHICDGRLILGIGSGWKQKDYDEYGYEFGTAGSRLDD
MAV_0061|M.avium_104 RNPELLADMARTVDHISEGRLILGIGSGWKQKDYDEYGYEFGTAGSRLDD
Mflv_0860|M.gilvum_PYR-GCK RNPELLADMARTVDHISDGRLILGIGSGWKQKDYDEYGYEFGTVGSRLDD
Mvan_6045|M.vanbaalenii_PYR-1 RNPELLADMARTVDHISDGRLILGIGSGWKRKDYDEYGYEFGTAGSRLDD
MSMEG_6907|M.smegmatis_MC2_155 RNPELLADMARTVDHISDGRLILGIGSGWKQKDYDEYGYEFGTAGSRLDD
TH_0517|M.thermoresistible__bu RNPDLLADMARTVDHISGGRLIFGIGSGWFRRDYDEYGYEFGTAGGRLDD
MAB_3016c|M.abscessus_ATCC_199 RNPDLLADMARTVDHISGGRLILGVGAGWYERDYTTYGYDFGTTGSRFDL
MLBr_00348|M.leprae_Br4923 RTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTRE
*.* * * *:**:. ** *:*:* . . ** * . .*
Rv0044c|M.tuberculosis_H37Rv LAAALPRIKARLGKLN------PPPTR--------------------DIP
Mb0045c|M.bovis_AF2122/97 LAAALPRIKARLGKLN------PPPTR--------------------DIP
MMAR_0063|M.marinum_M LAGALPRIKTRLAKLN------PAPTR--------------------DIP
MUL_0062|M.ulcerans_Agy99 LAGALPRIKTRLAKLI------PAPTR--------------------DIP
MAV_0061|M.avium_104 LAGALPRIEARLAKLN------PAPTR--------------------DIP
Mflv_0860|M.gilvum_PYR-GCK LAAALPRIESRLSKLN------PQPVR--------------------DIP
Mvan_6045|M.vanbaalenii_PYR-1 LAVAMPRIEARLDKLN------PQPVR--------------------DIP
MSMEG_6907|M.smegmatis_MC2_155 LAAALPRIRARLDKLN------PAPTR--------------------EIP
TH_0517|M.thermoresistible__bu LAAALPRIKARWAKLN------PPPTR--------------------ELP
MAB_3016c|M.abscessus_ATCC_199 FEDSLVRIESRLGQLL------PQPVR--------------------PIP
MLBr_00348|M.leprae_Br4923 YIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIP
: :: :* : * * :*
Rv0044c|M.tuberculosis_H37Rv VLIGGGGERKTLRLVAEYADIWHSFTAGDSYLAKSAVLSTHCSTVG--RN
Mb0045c|M.bovis_AF2122/97 VLIGGGGERKTLRLVAEYADIWHSFTAGDSYLAKSAVLSTHCSTVG--RN
MMAR_0063|M.marinum_M VLIGGGGERKTLRLVAEHADIWHSFTGVDEFPAKSAVLARHCADVG--RD
MUL_0062|M.ulcerans_Agy99 VLIGGGGERKTLRLVAEHADIWHSFTGVDEFPAKSAVLARHCADVG--RD
MAV_0061|M.avium_104 VLIGGGGERKTLRLVAQHADIWHSFTSAEEYPAKSEVLARHCADVG--RD
Mflv_0860|M.gilvum_PYR-GCK VLIGGGGERKTLRMVAQHAHIWHSFSDTETYPRKSEILARHCADVG--RD
Mvan_6045|M.vanbaalenii_PYR-1 VLIGGGGEKKTLRLVARHAQIWHSFSDTDSYPRKSDILARHCAEAG--RD
MSMEG_6907|M.smegmatis_MC2_155 ILIGGQGERKTLPLVAEHAHIWHAFVDRNTYPGKAEVLDSHCESVG--RD
TH_0517|M.thermoresistible__bu ILIGGMGEKKTLRLVAEHAHIWHGFVDRSTYPHKSRVLAEHCAAVG--RD
MAB_3016c|M.abscessus_ATCC_199 ILIGGGGEKRTIPLVARHAHIWHAFGDIDTYRRKNSVLIAEADRIG--RD
MLBr_00348|M.leprae_Br4923 IMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRS
:::*. * :.. . * * * *.
Rv0044c|M.tuberculosis_H37Rv PATIERSAAV----DGGGLIASAEALAGLGVTLLTVGCDGPD--------
Mb0045c|M.bovis_AF2122/97 PATIERSAAV----DGGGLIASAEALAGLGVTLLTVGCDGPD--------
MMAR_0063|M.marinum_M PATIERSAALQ---DSGRLSADADALAGLGVTLLTVGCDGPD--------
MUL_0062|M.ulcerans_Agy99 PATIERSAALQ---DSGRLSADADALAGLGVTLLTVGCDGPD--------
MAV_0061|M.avium_104 PDRIERSAAVK---GGAELLANAEALVGLGVTLLTVGCDGPD--------
Mflv_0860|M.gilvum_PYR-GCK PDAIERSAEAKGR-TEDALLENAAALTSLGVSMLTVGVNGPD--------
Mvan_6045|M.vanbaalenii_PYR-1 PATIERSAEAMGR-DADALIENADALHALGITMFTVGVNGPD--------
MSMEG_6907|M.smegmatis_MC2_155 AASIERSAGVQSDGGIEAMLAEADALADLGVTILTVGANGPD--------
TH_0517|M.thermoresistible__bu PDTIERSSGLPVEGGVDAALAEAAALVEQGVTLLTVGVNGPD--------
MAB_3016c|M.abscessus_ATCC_199 HNEIERSTSWGLDPERGLTAAEADAYVEVGARLFTVGIDADNG-------
MLBr_00348|M.leprae_Br4923 REDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRR
:* .: * . : :* :. :
Rv0044c|M.tuberculosis_H37Rv --YDLSAAAALCRWRDGR--------------------------------
Mb0045c|M.bovis_AF2122/97 --YDLSAAAALCRWRDGR--------------------------------
MMAR_0063|M.marinum_M --YDLAAAEALCRWRDSR--------------------------------
MUL_0062|M.ulcerans_Agy99 --YDLAAAEALCRWRDSR--------------------------------
MAV_0061|M.avium_104 --YDLRDAQALCKWRDGR--------------------------------
Mflv_0860|M.gilvum_PYR-GCK --YDLSQAETLCRWRDSHTAAG----------------------------
Mvan_6045|M.vanbaalenii_PYR-1 --YDLAQAEVLCRWRDRRQAGD----------------------------
MSMEG_6907|M.smegmatis_MC2_155 --YDLTAAEALCRWRDGRHAN-----------------------------
TH_0517|M.thermoresistible__bu --YDLSIAEALCRWRDNR--------------------------------
MAB_3016c|M.abscessus_ATCC_199 --YDLSVLDAPLAWRDSRS-------------------------------
MLBr_00348|M.leprae_Br4923 MGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAW
* . :*. :
Rv0044c|M.tuberculosis_H37Rv -------------------------
Mb0045c|M.bovis_AF2122/97 -------------------------
MMAR_0063|M.marinum_M -------------------------
MUL_0062|M.ulcerans_Agy99 -------------------------
MAV_0061|M.avium_104 -------------------------
Mflv_0860|M.gilvum_PYR-GCK -------------------------
Mvan_6045|M.vanbaalenii_PYR-1 -------------------------
MSMEG_6907|M.smegmatis_MC2_155 -------------------------
TH_0517|M.thermoresistible__bu -------------------------
MAB_3016c|M.abscessus_ATCC_199 -------------------------
MLBr_00348|M.leprae_Br4923 SAAGVTMMMVSASSVEQVRDLAGLF