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TDIVGASAGRHLQAIGPEALIGSVELLARSVRVALVSPAGQIVRRAEKEFPVTGDAAVLRETVQDTVFGC LQGSPLCGVGVASAGLVDHTTGVLRRIDDQPGFSGYPIAASLTRLLGCPVFVDHRARLQVLGDRWFGHGI GRASFASVATGDTLGLGILFEGKVIAPLGGRSGAHITVALGGRRCSCGNLGCWKTIATSTWLRQEAATRG LGPIDGVGDLIAAARGDTGARRLMTDYADNLAVGLSSVQHLLAPGLYIVHGDAAAGGGTFLGRIEERLRA VSEWADFAERPRVVAADTAADDVALLGGAGLVLSRLSGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6869 | - | - | 100% (320) | regulatory protein |
| M. smegmatis MC2 155 | MSMEG_1363 | - | 5e-18 | 26.62% (308) | glucokinase |
| M. smegmatis MC2 155 | MSMEG_0316 | - | 1e-16 | 30.29% (208) | putative NagC regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0669 | - | 7e-19 | 29.35% (293) | sugar kinase |
| M. gilvum PYR-GCK | Mflv_5102 | - | 2e-22 | 30.46% (302) | ROK family protein |
| M. tuberculosis H37Rv | Rv0650 | - | 7e-19 | 29.35% (293) | sugar kinase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0987 | - | 1e-14 | 28.33% (300) | carbohydrate kinase |
| M. avium 104 | MAV_4510 | - | 5e-21 | 28.43% (299) | sugar kinase |
| M. thermoresistible (build 8) | TH_4374 | - | 5e-16 | 28.85% (305) | PUTATIVE glucokinase |
| M. ulcerans Agy99 | MUL_0739 | - | 1e-14 | 28.33% (300) | carbohydrate kinase |
| M. vanbaalenii PYR-1 | Mvan_1251 | - | 3e-23 | 30.62% (307) | ROK family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0669|M.bovis_AF2122/97 -------------------MLTLCLDIGGTKIAAGLADPAGTLVHTAQRP
Rv0650|M.tuberculosis_H37Rv -------------------MLTLCLDIGGTKIAAGLADPAGTLVHTAQRP
MMAR_0987|M.marinum_M -------------------MLTLCLDIGGTKVAVGLADADGALVHTAQVP
MUL_0739|M.ulcerans_Agy99 -------------------MLTLCLDIGGTKVAVGLADADGALVHTAQVP
MAV_4510|M.avium_104 -------------------MLTLGLDIGGTKIAAALVDSSGTLVHTAVRP
TH_4374|M.thermoresistible__bu -------------------VLTLTLDIGGTKLAAGLVDGDGGLVHHTHAA
Mflv_5102|M.gilvum_PYR-GCK -------------MALSMSDLTLTLDIGGTKLAAGLVDADGNLVRRAQTP
Mvan_1251|M.vanbaalenii_PYR-1 -----------------MNDLVLALDIGGTKIAAGLVDADGTLVHRAQQP
MSMEG_6869|M.smegmatis_MC2_155 MTDIVGASAGRHLQAIGPEALIGSVELLARSVRVALVSPAGQIVRRAEKE
* ::: . .: ..*.. * :*: :
Mb0669|M.bovis_AF2122/97 TPAYGGAEQVWAAVAEMIADALGVAGGAVGGVGIASAGPIDLHSGRVSPI
Rv0650|M.tuberculosis_H37Rv TPAYGGAEQVWAAVAEMIADALGVAGGAVGGVGIASAGPIDLHSGRVSPI
MMAR_0987|M.marinum_M TPARCAAEQVWAAVAEAIAEALRVADATVAAVGIASAGPVDLDSGTVSPI
MUL_0739|M.ulcerans_Agy99 TPARCAAEQVWAAVAEAIAEALRVADATVAAVGIASAGPVDLDSGTVSPI
MAV_4510|M.avium_104 TPNPAPADDVWDVVHALIAEVVRAADAPIAAVGIASAGPVDLPSGSVSPI
TH_4374|M.thermoresistible__bu TPG-GDAEAVWTVLAGLIDDALTRAGGRVRAVGVGSAGPIDLTAGTVSPI
Mflv_5102|M.gilvum_PYR-GCK TPD-GDAETIWDAVASLLAETRSAADSTIGAVGIASAGPVDVPAGTVSPI
Mvan_1251|M.vanbaalenii_PYR-1 TPD-GDAETVWDTAAALLAETRDAAPGPVSAVGIGSAGPIDVPGGTVSPI
MSMEG_6869|M.smegmatis_MC2_155 FPVTGDAAVLRETVQDTVFGCLQGS--PLCGVGVASAGLVDHTTGVLRRI
* * : . : : : .**:.*** :* * : *
Mb0669|M.bovis_AF2122/97 N-IGSWGGFPLRDRVAAAVPGVPVRLGGDGVCMALGEHWLGAGRGARFLL
Rv0650|M.tuberculosis_H37Rv N-IGSWGGFPLRDRVAAAVPGVPVRLGGDGVCMALGEHWLGAGRGARFLL
MMAR_0987|M.marinum_M N-IGSWRGFPLRDRVAAMVPDVPVRLGGDGVCMALGEHWLGAGRGARFLL
MUL_0739|M.ulcerans_Agy99 N-IGSWRGFPLRDRVAAMVPDVPVRLGGDGVCMALGEHWLGAGRGARFLL
MAV_4510|M.avium_104 N-IAGWHRFPLRDKVAAAVPATPVVLGGDGLCMALGEQWLGAGRGARFLL
TH_4374|M.thermoresistible__bu N-LTAWSRFPLTERVSAALPGVPVRLGGDGLCMAMGEQWRGAGRGARFVL
Mflv_5102|M.gilvum_PYR-GCK N-IAEWHRFPIVERVEAAT-GLPVYLGGDGLCMAMGEWWRGAGRNRRFML
Mvan_1251|M.vanbaalenii_PYR-1 N-IAEWSHFPIVRRVADLT-GLPVRLGGDGLCMALGEWWRGAGRGAGFLL
MSMEG_6869|M.smegmatis_MC2_155 DDQPGFSGYPIAASLTRLL-GCPVFVDHRARLQVLGDRWFGHGIGRASFA
: : :*: : ** :. . .:*: * * * . .
Mb0669|M.bovis_AF2122/97 GLVVSTGVGGGLVLDGAPCLGRTGNAGHVGHVVVDPDGSPCPCGGRGCVE
Rv0650|M.tuberculosis_H37Rv GLVVSTGVGGGLVLDGAPCLGRTGNAGHVGHVVVDPDGSPCPCGGRGCVE
MMAR_0987|M.marinum_M GMVVSTGVGGGLVLGGVPYPGRTGNAGHVGHVVVDQDGLRCSCGGRGCVE
MUL_0739|M.ulcerans_Agy99 GMVVSTGVGGGLVLGGVPYPGRTGNAGHVGHVVVDQDGLRCSCGGRGCVE
MAV_4510|M.avium_104 GMVVSTGVGGGLVLDGAPYPGRTGNAGHVGHVVVELDGRPCTCGGHGCVE
TH_4374|M.thermoresistible__bu GIVVSTGVGGGLVLDGMPYQGRTGNAGHVGHVVVDPRGVACSCGGRGCVE
Mflv_5102|M.gilvum_PYR-GCK GMVVSTGIGGGLVLDGAPFHGRTGNAGHVGHVVVEPDGDACTCGGRGCVE
Mvan_1251|M.vanbaalenii_PYR-1 GMVVSTGIGGGLVLDGAPYHGRSGNAGHVGHVVVEPGGAPCTCGGRGCVE
MSMEG_6869|M.smegmatis_MC2_155 SVATGDTLGLGILFEGKVIAPLGGRSG--AHITVALGGRRCSCGNLGCWK
.:... :* *::: * *.:* .*:.* * *.**. ** :
Mb0669|M.bovis_AF2122/97 TIASGPSLARWARANGWSAPPGAGAKELAEAAGAGDPVALRAFRRGAAAL
Rv0650|M.tuberculosis_H37Rv TIASGPSLARWARANGWSAPPGAGAKELAEAAGAGDPVALRAFRRGAAAL
MMAR_0987|M.marinum_M TIAAGPSMVRWARANGWSARPEAGARELAAAAAAGDAVALAAFRRGTRGL
MUL_0739|M.ulcerans_Agy99 TIAAGPSMVRWARANGWSARPEAGARELAAAAAAGDAVALAAFRRGTRGL
MAV_4510|M.avium_104 TVASGPSMVRWARENGWSAAPGAGARDLAAAAAS-DPLAQKAFHRSADAL
TH_4374|M.thermoresistible__bu TMAAGPAMVRWARANGWNAPPDADAEDLAAAAAAGVPVAVRAYRRGADAL
Mflv_5102|M.gilvum_PYR-GCK TVASGPHLARWARAHGWEG---ADARELAEAAGRGEDVALRAFARGADAV
Mvan_1251|M.vanbaalenii_PYR-1 TVASGPHLARWAHDNGWAAAPDADAKDLAEAAGRGDPVALRAFARGADAV
MSMEG_6869|M.smegmatis_MC2_155 TIATSTWLRQEAATRGLGP---IDGVGDLIAAARGDTGARRLMTDYADNL
*:*:.. : : * .* .. **. * : :
Mb0669|M.bovis_AF2122/97 AAMIASVGAVCDLDLAVIGGGVAKSGRLLFEPLRAALADHAR-LDFLAGL
Rv0650|M.tuberculosis_H37Rv AAMIASVGAVCDLDLAVIGGGVAKSGRLLFEPLRAALADHAR-LDFLAGL
MMAR_0987|M.marinum_M AAMIASVGAVCDLDRVVIGGGVAKAGRLLFDPLRAALADYLG-LDFLAGL
MUL_0739|M.ulcerans_Agy99 AAMIASVGAVCDLDRVVIGGGVAKAGRLLFDPLRAALADYLG-LDFLAGL
MAV_4510|M.avium_104 AAMIASVGAVCDLDVVVIGGGVAQSGPLLFDPLRERLAHYAG-LDFLSGL
TH_4374|M.thermoresistible__bu AAAISSVAAVCDLDLVVIGGGVARSGPVLFDPLAEALTTYTG-LSFLRGL
Mflv_5102|M.gilvum_PYR-GCK ARTIASVAAVCDLDLVVVGGGVAKAGSLLFDPLHQALRTYAG-LDFLTDL
Mvan_1251|M.vanbaalenii_PYR-1 ARTIASVAAVCDLDLVVVGGGVAKAGALLFDPLRQALTMYAG-LEFLRGL
MSMEG_6869|M.smegmatis_MC2_155 AVGLSSVQHLLAPGLYIVHGDAAAGGGTFLGRIEERLRAVSEWADFAERP
* ::** : . :: *..* .* :: : * .*
Mb0669|M.bovis_AF2122/97 RVVPAELGG-AAGLVGAARLAAIA-----
Rv0650|M.tuberculosis_H37Rv RVVPAELGG-AAGLVGAARLAAIA-----
MMAR_0987|M.marinum_M RVVPAELGG-QAGLVGAARLAGLG-----
MUL_0739|M.ulcerans_Agy99 RVVPAELGG-QAGLVGAARLAGLG-----
MAV_4510|M.avium_104 TVVPGELGG-NAGLIGAARLATLARPAGS
TH_4374|M.thermoresistible__bu RVVPARLGA-TAGLIGAARLAISAC----
Mflv_5102|M.gilvum_PYR-GCK RVVPAELGG-DAGLVGAAALAAHHGRFG-
Mvan_1251|M.vanbaalenii_PYR-1 RVVPAELGG-DAGLVGAAALVHDSVRFG-
MSMEG_6869|M.smegmatis_MC2_155 RVVAADTAADDVALLGGAGLVLSRLSGQ-
**.. .. ..*:*.* *.