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VLQRVPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHR HTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVITAAGVSSGIDMGL RLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLALEFYQHRL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0052 | - | - | 100% (187) | hypothetical protein Rv0052 |
| M. tuberculosis H37Rv | Rv1930c | - | 3e-15 | 43.01% (93) | hypothetical protein Rv1930c |
| M. tuberculosis H37Rv | Rv1931c | - | 6e-05 | 38.00% (50) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0053 | - | 1e-105 | 100.00% (187) | hypothetical protein Mb0053 |
| M. gilvum PYR-GCK | Mflv_5266 | - | 9e-40 | 44.13% (179) | ThiJ/PfpI domain-containing protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0943 | - | 9e-39 | 46.67% (180) | hypothetical protein MAB_0943 |
| M. marinum M | MMAR_0071 | - | 6e-75 | 69.89% (186) | transcriptional regulatory protein |
| M. avium 104 | MAV_0073 | - | 2e-72 | 69.35% (186) | DJ-1/PfpI family protein |
| M. smegmatis MC2 155 | MSMEG_1107 | - | 9e-37 | 44.00% (175) | isonitrile hydratase, putative |
| M. thermoresistible (build 8) | TH_3120 | - | 2e-10 | 31.10% (164) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_0070 | - | 4e-75 | 69.89% (186) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0973 | - | 4e-39 | 43.02% (179) | ThiJ/PfpI domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0052|M.tuberculosis_H37Rv ------------------------------MPSFDVVFVGHRRGEVRSDN
Mb0053|M.bovis_AF2122/97 ------------------------------MPSFDVVFVGHRRGEVRSDN
MMAR_0071|M.marinum_M -----MQVAIPVFPRFTALDAVGPYEVLQRIPSIDVVFIGHQRGEVRTEN
MUL_0070|M.ulcerans_Agy99 -----MQVAIPVFPRFTALDAVGPYEVLQRIPSIDVVFIGHQRGEVRTEN
MAV_0073|M.avium_104 ----MTLIAIPLFPRVTALDAVGPYEVLQRIPSVQVVFIGQRRGEVRTEN
MAB_0943|M.abscessus_ATCC_1997 MTSAATQIAIVLYPDFTALDFIGPYEVLRFIPDTEVRFVWHEPGPVTADS
MSMEG_1107|M.smegmatis_MC2_155 -----MQIAVVLYPTFTALDFIGPYEVLRNLPDAEVRFVWHEPGPVTADS
Mflv_5266|M.gilvum_PYR-GCK -----MQVAIMLYPGFTALDFIGPYESLRWLPDTEVRFVWHEPGPIAADS
Mvan_0973|M.vanbaalenii_PYR-1 -----MQVAIMLYPGFTALDFIGPYESLRWLPDVEVRFVWHEPGPIAADS
TH_3120|M.thermoresistible__bu -VAALVLDGLAIFEFGVICEVFGVDRTDDGVPPVDFTVCGPRAGQPVRTS
:* :. . . * .
Rv0052|M.tuberculosis_H37Rv AMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHTLL
Mb0053|M.bovis_AF2122/97 AMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHTLL
MMAR_0071|M.marinum_M GMLGVTCDATFAEVDAPDVVVFPGGIGTRGLLEDETIRGWLQAVHPHTRF
MUL_0070|M.ulcerans_Agy99 GMLGVTCDATFDEVDAPDVVAFPGGIGTRGLLEDETIRGWLQAVHPHTRF
MAV_0073|M.avium_104 GMLGLACDATFDEVSAPDVVVFPGGIGTRQLIHDEAVRAWLQAVHPHTRF
MAB_0943|M.abscessus_ATCC_1997 GVLVIGATHSFGETPAPDVVLVPGGPGTTMAARDDKLLDWLRRVHPAAAW
MSMEG_1107|M.smegmatis_MC2_155 GVLMVGATHTFDETPSPDVVLVPGGPGSSAAARDERVLAWLRAVHPTANW
Mflv_5266|M.gilvum_PYR-GCK HVLLVGATHSFDETPSPDVILIPGGFATMEHARDEVVLAWVRRAHETSTW
Mvan_0973|M.vanbaalenii_PYR-1 HVLLVGATHSFDETPSPDLILIPGGFATMEHARDEKVLDWVRRAHRTSTW
TH_3120|M.thermoresistible__bu FGATLTPDSGLDGLAGADLVAIP---AIRQDDYLPEALDAVRAAADAGAI
: : .*:: .* . :: .
Rv0052|M.tuberculosis_H37Rv TTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVP-QRVVEHLP
Mb0053|M.bovis_AF2122/97 TTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVP-QRVVEHLP
MMAR_0071|M.marinum_M TTSVCTGALLLAAAGLLDGLTATTHWRAAELLNGLGARYVP-QRVVEHLP
MUL_0070|M.ulcerans_Agy99 TTSVCTGALLLAAAGLLDGLTATTHWRAAELLNGLGARYVP-QRVVEHLP
MAV_0073|M.avium_104 TTSVCTGALLLAAAGLLDGLTATTHWRAADLLKGLGARYVE-QRVVEHLP
MAB_0943|M.abscessus_ATCC_1997 TTSVCSGSLVLAAAGLLEGQRATSHWSTLPLLKPFGVTPVGDERIVRTGH
MSMEG_1107|M.smegmatis_MC2_155 VASVCSGSMVLAAAGLLDGKRATSHWGALSALKMCGVTAVSDERIVRADD
Mflv_5266|M.gilvum_PYR-GCK TTSVCSGSVILAAAGVLDGKRATSHWAALPVLKTLGAQPVGDQRIVEADA
Mvan_0973|M.vanbaalenii_PYR-1 TTSVCSGSVILAASGVLDGKRATSHWAALPVLKTFGVQPVGDERVVVADD
TH_3120|M.thermoresistible__bu ILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELARRYPTARVDRNVLYVDD
:**:*..: .*:*:*:* .*:** : ..::
Rv0052|M.tuberculosis_H37Rv ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQ---------
Mb0053|M.bovis_AF2122/97 ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQ---------
MMAR_0071|M.marinum_M QRIITAAGVSSGIDMGLRLVELLVDREAAQAAQLLIEYDPE---------
MUL_0070|M.ulcerans_Agy99 QRIITAAGVSSGIDMGLRLVELLVDREAAQVTQLLIEYDPE---------
MAV_0073|M.avium_104 QRIITAAGVSSGIDMALRLVELLVDRQAAQAAQLLIEYDPQ---------
MAB_0943|M.abscessus_ATCC_1997 AGLVTAAGVSAGIDLGLWLAGQIAGEERAKAIQLSIEYDPQ---------
MSMEG_1107|M.smegmatis_MC2_155 K-VITAAGVSAGIDLGMWLAGQIAGEAKAKAIQLLIEYDPQ---------
Mflv_5266|M.gilvum_PYR-GCK K-TVTAAGVSAGIDLGLWLAGRIAGEEKAKAIQLSMEYDPQ---------
Mvan_0973|M.vanbaalenii_PYR-1 K-TVTAAGVSAGIDLGLWLAGQIAGESKAKAIQLSMEYDPQ---------
TH_3120|M.thermoresistible__bu GDLITSAGTAAGIDACLHLVRRELGSEVTNTIARHMVVPPQRDGGQRQFI
:*:**.::*** : *. . ::. : *:
Rv0052|M.tuberculosis_H37Rv -PPVDAGSLA------------------------KASPATHRLALEFYQH
Mb0053|M.bovis_AF2122/97 -PPVDAGSLA------------------------KASPATHRLALEFYQH
MMAR_0071|M.marinum_M -PPFDAGSLA------------------------KADEGVRARAIEFLDS
MUL_0070|M.ulcerans_Agy99 -PPFDAGSLA------------------------KADEGVRARAIEFLDS
MAV_0073|M.avium_104 -PPFDSGALG------------------------KADAATVARAEEYLTG
MAB_0943|M.abscessus_ATCC_1997 -PPFDSGHMS------------------------KASAATKATATAGLAK
MSMEG_1107|M.smegmatis_MC2_155 -PPFDAGHMS------------------------KASATTKAGATALLGR
Mflv_5266|M.gilvum_PYR-GCK -PPFDSGHMS------------------------KASAGTKALATAMMGR
Mvan_0973|M.vanbaalenii_PYR-1 -PPFDSGHMS------------------------KASASTKALATAMMGR
TH_3120|M.thermoresistible__bu DQPIPVRHSEGFAPHLDWILSNLDKTHTVASLARRANMSPRTFARRFVEE
*. :*. *
Rv0052|M.tuberculosis_H37Rv RL------------------------------------------------
Mb0053|M.bovis_AF2122/97 RL------------------------------------------------
MMAR_0071|M.marinum_M RK------------------------------------------------
MUL_0070|M.ulcerans_Agy99 RK------------------------------------------------
MAV_0073|M.avium_104 RR------------------------------------------------
MAB_0943|M.abscessus_ATCC_1997 DTFKPSVMAAGAKLLWDGALATARRRGDRRRSFGSRLDPRARP-------
MSMEG_1107|M.smegmatis_MC2_155 DMIKPEPLKASVLLAWDQAIRRVRGRGAARRTA-----------------
Mflv_5266|M.gilvum_PYR-GCK EMVRPAALAASTGLLWDAALKRIRRA--KRRQ--GSLSAP----------
Mvan_0973|M.vanbaalenii_PYR-1 EMAKPAALAASTGLLWDAALKRIRAR--RSRPEPAKLRGGS---------
TH_3120|M.thermoresistible__bu TGRTPMQWVTDQRVLYARRLLEETDLDIHRIAARCGFGSTTLLRHHFRRV
Rv0052|M.tuberculosis_H37Rv ------------------------------
Mb0053|M.bovis_AF2122/97 ------------------------------
MMAR_0071|M.marinum_M ------------------------------
MUL_0070|M.ulcerans_Agy99 ------------------------------
MAV_0073|M.avium_104 ------------------------------
MAB_0943|M.abscessus_ATCC_1997 ------------------------------
MSMEG_1107|M.smegmatis_MC2_155 ------------------------------
Mflv_5266|M.gilvum_PYR-GCK ------------------------------
Mvan_0973|M.vanbaalenii_PYR-1 ------------------------------
TH_3120|M.thermoresistible__bu IGVTPSDYRRRFACGSTTSGSTESGAEVTD