For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MGRLMVITPIPHPWLIWCRDLMSSYRAYQVTGRRKFELVQREIRDPAEEQVRIRTLACGVCHSDALAVEG QRPNPEEPVVPGHEVVGVVDAVGSGIQERWRIGERVGVGFLGGQCGHCDYCRRGDFVNCLDQPLTGTTVD GGYSEMLYVRESALVRVPEGFDALTAAPLLCAGVTVFNALRAGDAPPNTLVAVQGLGGLGHLGVQYAKKL GYEVAAIARGTDKADLAATLGADHYIDSATEDVAAGLTRLGGAAAVVATASSGQSMAGLVAGLRPRGRLV VVGAAPDPIPVQTPDLIFGGRTIVGSLTGSAIDNEDNLAFSLNHQIAPMIERMPFTEAPQAYERMMSGHA RFRVVLDFS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6833 | - | - | 100% (359) | alcohol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6834 | - | 1e-86 | 48.50% (334) | alcohol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3464 | - | 6e-71 | 42.43% (337) | alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3071 | adhC | 2e-48 | 35.49% (324) | NADP-dependent alcohol dehydrogenase ADHC |
| M. gilvum PYR-GCK | Mflv_0236 | - | 1e-74 | 43.45% (336) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv3045 | adhC | 2e-48 | 35.49% (324) | NADP-dependent alcohol dehydrogenase ADHC |
| M. leprae Br4923 | MLBr_01730 | adhA | 8e-52 | 33.82% (346) | alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3400 | - | 5e-46 | 33.62% (345) | NADP-dependent alcohol dehydrogenase C |
| M. marinum M | MMAR_2782 | adhC | 2e-77 | 43.15% (336) | NADP-dependent alcohol dehydrogenase AdhC |
| M. avium 104 | MAV_2812 | - | 3e-77 | 45.94% (320) | aldehyde dehydrogenase family protein |
| M. thermoresistible (build 8) | TH_4581 | - | 1e-49 | 34.78% (345) | PUTATIVE alcohol dehydrogenase, zinc-containing |
| M. ulcerans Agy99 | MUL_2965 | adhC | 1e-79 | 44.05% (336) | NADP-dependent alcohol dehydrogenase AdhC |
| M. vanbaalenii PYR-1 | Mvan_0669 | - | 2e-75 | 43.75% (336) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2782|M.marinum_M ---------------------MATHKAVQIGAAGGLLQLVDVDTAPPGDG
MUL_2965|M.ulcerans_Agy99 ---------------------MATHKAVQIGAAGGPLQLVDVDTAPPADG
MAV_2812|M.avium_104 ------------------------------------MELVDTETRPPGRD
Mflv_0236|M.gilvum_PYR-GCK ---------------------MPTHKAVHVAGANEDLTLVEVETAPPPPG
Mvan_0669|M.vanbaalenii_PYR-1 ---------------------MPTHKAVQVPSANEALTHVEVDTLPPPAG
MSMEG_6833|M.smegmatis_MC2_155 MGRLMVITPIPHPWLIWCRDLMSSYRAYQVTGR-RKFELVQREIRDPAEE
Mb3071|M.bovis_AF2122/97 ---------------------MSTVAAYAAMSATEPLTKTTITRRDPGPH
Rv3045|M.tuberculosis_H37Rv ---------------------MSTVAAYAAMSATEPLTKTTITRRDPGPH
MLBr_01730|M.leprae_Br4923 -----MKSHVSKHRRKRRLGAMTTVSAYAATSATEPLTKVTINRRAPGPH
TH_4581|M.thermoresistible__bu ---------------------MTTVSAYAATSVSEPLTRTTITRREMGPH
MAB_3400|M.abscessus_ATCC_1997 ---------------------MVTVSAYAATSGKDPLVPTTIERREVGPH
: .
MMAR_2782|M.marinum_M EVRISVSACGICGTDRAFVHGAFPGLGWPLTPGHEIAGRIAEIGNGVED-
MUL_2965|M.ulcerans_Agy99 EVRISVSACGICGTDRAFVHGAFPGLDWPLTPGHEIAGRIAEIGNGVED-
MAV_2812|M.avium_104 EVRLTVGACGICGTDAHFVNGAFPGLSWPLTPGHEIAGRIAELGEGVEG-
Mflv_0236|M.gilvum_PYR-GCK HVRLAVKACGVCGTDREFRAGHFPGLQWPLTLGHEIAGAVAEVGDGVED-
Mvan_0669|M.vanbaalenii_PYR-1 HVRIDVAACGVCGTDREFRAGHFPGLQWPITLGHEIAGTVAELGDGVEE-
MSMEG_6833|M.smegmatis_MC2_155 QVRIRTLACGVCHSDALAVEGQRPNPEEPVVPGHEVVGVVDAVGSGIQER
Mb3071|M.bovis_AF2122/97 DVAIDIKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGSEVTK-
Rv3045|M.tuberculosis_H37Rv DVAIDIKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGSEVTK-
MLBr_01730|M.leprae_Br4923 DVAIQIKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGTEVTK-
TH_4581|M.thermoresistible__bu DVTIAIHFAGICHSDIHTVKGEWGEPAFPLVPGHEIAGVVTAVGSEVTR-
MAB_3400|M.abscessus_ATCC_1997 DVFIDIKFAGICHSDIHTVRDEWGRANYPIVPGHEIAGVITEVGSEVTK-
.* : .*:* :* *:. ***:.* : :* :
MMAR_2782|M.marinum_M FAVGDRVAVGWFGGNCNHCDPCRKGMFIHCAK--------MKVPGWQYPG
MUL_2965|M.ulcerans_Agy99 FAVGDRVAVGWFGGNCNHCDPCRKGMFIHCSK--------MKVPGWQYPG
MAV_2812|M.avium_104 FAVGQRVAVGWFGGCCYRCDPCRAGLFIHCVN--------GKVPSWHYPG
Mflv_0236|M.gilvum_PYR-GCK FSVGDRVAVGWFGGNCNRCIPCRRGSFMQCER--------MQVPSWHYPG
Mvan_0669|M.vanbaalenii_PYR-1 FAVGDRVAVGWFGGNCNRCVPCRRGFFMQCER--------MQVPSWQYPG
MSMEG_6833|M.smegmatis_MC2_155 WRIGERVGVGFLGGQCGHCDYCRRGDFVNCLD--------QPLTGTTVDG
Mb3071|M.bovis_AF2122/97 YRQGDRVGVGCFVDSCRECNSCTRGIEQYCKPGANFTYNSIGKDGQPTQG
Rv3045|M.tuberculosis_H37Rv YRQGDRVGVGCFVDSCRECNSCTRGIEQYCKPGANFTYNSIGKDGQPTQG
MLBr_01730|M.leprae_Br4923 HKVGDRVGVGCMVGSCGECSSCLAGIEQYCKRGATFTYNSIGTDGQSTQG
TH_4581|M.thermoresistible__bu YRVGDRVGVGCFVDSCRECRHCLAGDEQYCVRGMTGTYNGVDRDGRPTQG
MAB_3400|M.abscessus_ATCC_1997 FKPGDHAGVGCFVNSCRECPSCLAGLEQFCERGMVGTYGAKDRDGTQTQG
*::..** : . * .* * * * . *
MMAR_2782|M.marinum_M GYAESVTVPATALARIPAELSDAEAAPMGCAGVTTYNALRHTRARPGDRV
MUL_2965|M.ulcerans_Agy99 GYAESVTVPATALARIPAELSDAEAAPMGCAGVTTYNALRHTRARPGDRV
MAV_2812|M.avium_104 GYAESVTVPTSALARIPEELTDAEAAPMGCAGVTTYNALRHTKALPGDRV
Mflv_0236|M.gilvum_PYR-GCK GYAESVTVPWTALARIPDGLSFVEAAPMGCAGVTTFNGLRQTRAKAGDVV
Mvan_0669|M.vanbaalenii_PYR-1 GYAESVTAPATALARIPDGLSFVEAAPMGCAGVTTFNGLRRTRAKAGDLV
MSMEG_6833|M.smegmatis_MC2_155 GYSEMLYVRESALVRVPEGFDALTAAPLLCAGVTVFNALRAGDAPPNTLV
Mb3071|M.bovis_AF2122/97 GYSEAIVVDENYVLRIPDVLPLDVAAPLLCAGITLYSPLRHWNAGANTRV
Rv3045|M.tuberculosis_H37Rv GYSEAIVVDENYVLRIPDVLPLDVAAPLLCAGITLYSPLRHWNAGANTRV
MLBr_01730|M.leprae_Br4923 GYSQAIVVDENFVVHIPDALPLDAAAPLLCAGITLYSPLRHWNAKPGTRL
TH_4581|M.thermoresistible__bu GYSGAIVVDENYVLRIPDSLPLDAAAPLLCAGITTYSPLRHWNVGPGTRV
MAB_3400|M.abscessus_ATCC_1997 GYSQAIVVDENYVLRIPDSLPLDAAAPLLCAGITTFSPLRHWNAGPGKRV
**: : . . : ::* : ***: ***:* :. ** . .. :
MMAR_2782|M.marinum_M AVLGVGGLGHLGLQFCRAMGFETVAIARGSAKAEDARQLGAHHYIDSTTG
MUL_2965|M.ulcerans_Agy99 AVLGVGGLGHLGLQFCRAMGFETVAIARGSAKAEDARQLGAHHYIDSTTG
MAV_2812|M.avium_104 AILGVGGLGHLGVQFAAAMGFETIAINRGTGKADDARKLGAHHYIDSTAE
Mflv_0236|M.gilvum_PYR-GCK AVLGVGGLGHLGVQWSRAMGFETVAIARGTGKAEEARELGAHHYIDSTGQ
Mvan_0669|M.vanbaalenii_PYR-1 AVLGVGGLGHLGVQWARAMGFETVAIGRGTGKAEEATQFGAHHYIDSTGQ
MSMEG_6833|M.smegmatis_MC2_155 AVQGLGGLGHLGVQYAKKLGYEVAAIARGTDKADLAATLGADHYIDSATE
Mb3071|M.bovis_AF2122/97 AIIGLGGLGHMGVKLGAAMGADVTVLSQSLKKMEDGLRLGAKSYYATADP
Rv3045|M.tuberculosis_H37Rv AIIGLGGLGHMGVKLGAAMGADVTVLSQSLKKMEDGLRLGAKSYYATADP
MLBr_01730|M.leprae_Br4923 AIIGLGGLGHMGVKLGRKMGCEVTVLSQSLKKMEDGLQLGASNYYATADP
TH_4581|M.thermoresistible__bu AVVGLGGLGHMAVKLGKALGADVTVLSQSLKKREDGLRLGAGAYYATSDP
MAB_3400|M.abscessus_ATCC_1997 AVVGLGGLGHMAVKLGKAMGAEVTVLSQSLKKMEDGLRLGASHYYATADP
*: *:*****:.:: :* :. .: :. * : . :** * ::
MMAR_2782|M.marinum_M DVAEALRRIGGAAVVLATAGNSAAMAETVGGLLPRGELVVIGVTADPLPI
MUL_2965|M.ulcerans_Agy99 DVAEGLRRIGGAAVVLATAGNSAAMAETVGGLLPRGELVVIGVTADPLPI
MAV_2812|M.avium_104 DPAEALRALGGAAVVLATAGNSQAMAATVGGLAPQGELVTIGVTPEPLPI
Mflv_0236|M.gilvum_PYR-GCK DVAAELKKLGGAAVVLATANNAEAMAATVGGLGPAGELVVVGVSADNLPI
Mvan_0669|M.vanbaalenii_PYR-1 DVAAELTKLGGASVVLATANNAAAMAAAVGGLGPAGELVVVGVTAENLPI
MSMEG_6833|M.smegmatis_MC2_155 DVAAGLTRLGGAAAVVATASSGQSMAGLVAGLRPRGRLVVVGAAPDPIPV
Mb3071|M.bovis_AF2122/97 DTFRKLR--GGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAV
Rv3045|M.tuberculosis_H37Rv DTFRKLR--GGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAV
MLBr_01730|M.leprae_Br4923 DTFRKLR--GSFDLILNTVSANLDLGKYLNLLDVNGTLVELGIPEHPMLV
TH_4581|M.thermoresistible__bu DTFRALR--SSFDVVINTVSANLDLGRYLMLLDVDGTLVELGMPEKPMTV
MAB_3400|M.abscessus_ATCC_1997 DTFKSLR--NSFDLILNTVSSNLDMGKYLGLLGVDGTLVELGLPENPIEV
* * .. :: *.. :. : * * ** :* . . : :
MMAR_2782|M.marinum_M SPVQLINPGLSVTGHPSGTAKDVEETMHFAVLSGVRAWIEERPLAQAADG
MUL_2965|M.ulcerans_Agy99 SPVQLINPGLSVTGHPSGTAKDVEDTMHFAVLSGVRAWIEERPLAQAADG
MAV_2812|M.avium_104 SPLQLITPGLSIVGHPSGTAKDVEDTMQFAVLSGVRAWIEELPLSRAADG
Mflv_0236|M.gilvum_PYR-GCK SPLHLINDGLSVTGHPSGTSRDVEETLHFAMLSGVRARVEEVPLAQPAEA
Mvan_0669|M.vanbaalenii_PYR-1 SPLDLINAGRSVTGHPSGTSRDVEETMHFALLSGVRAKVEEVPLARAAEA
MSMEG_6833|M.smegmatis_MC2_155 QTPDLIFGGRTIVGSLTGSAIDNEDNLAFSLNHQIAPMIERMPFTEAPQA
Mb3071|M.bovis_AF2122/97 PAFALALMRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDA
Rv3045|M.tuberculosis_H37Rv PAFALALMRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDA
MLBr_01730|M.leprae_Br4923 PAFALALMRRSLAGSNIGGITETQEMMNFSAEHSVTPEIELIEPDYINEA
TH_4581|M.thermoresistible__bu PAAPLVGGRRRLAGSLIGGIAETQEMLDFCAEHGVLPEIEVIEPEYINTA
MAB_3400|M.abscessus_ATCC_1997 PGFPLLTNRRSISGSLIGGIPETQEMLDFCAKHGIGSEIEVIDASYINEA
* : * * : :: : *. : . :* .
MMAR_2782|M.marinum_M YEAMEQGRTRYRTVLAM-----
MUL_2965|M.ulcerans_Agy99 YEAMEQGRTRYRTVLAM-----
MAV_2812|M.avium_104 YAALEGGRAHYRTVLTM-----
Mflv_0236|M.gilvum_PYR-GCK YEAMDSSRARYRMVLTV-----
Mvan_0669|M.vanbaalenii_PYR-1 YESMDSGRARYRMVLTM-----
MSMEG_6833|M.smegmatis_MC2_155 YERMMSGHARFRVVLDFS----
Mb3071|M.bovis_AF2122/97 YERVLASDVRYRFVIDISAL--
Rv3045|M.tuberculosis_H37Rv YERVLASDVRYRFVIDISAL--
MLBr_01730|M.leprae_Br4923 YERVLASDVRYRFVINISSL--
TH_4581|M.thermoresistible__bu YERVLASDVRYRFVIDTASLRG
MAB_3400|M.abscessus_ATCC_1997 YERVVASDVRYRFVIDTQTL--
* : . .::* *: