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MSTVAAYAAMSATEPLTKTTITRRDPGPHDVAIDIKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVT AVGSEVTKYRQGDRVGVGCFVDSCRECNSCTRGIEQYCKPGANFTYNSIGKDGQPTQGGYSEAIVVDENY VLRIPDVLPLDVAAPLLCAGITLYSPLRHWNAGANTRVAIIGLGGLGHMGVKLGAAMGADVTVLSQSLKK MEDGLRLGAKSYYATADPDTFRKLRGGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAVPAFA LALMRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDAYERVLASDVRYRFVIDISAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3045 | adhC | - | 100% (346) | PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC |
| M. tuberculosis H37Rv | Rv1862 | adhA | 5e-28 | 27.58% (330) | alcohol dehydrogenase AdhA |
| M. tuberculosis H37Rv | Rv0761c | adhB | 1e-23 | 28.06% (310) | zinc-containing alcohol dehydrogenase NAD dependent ADHB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3071 | adhC | 0.0 | 100.00% (346) | NADP-dependent alcohol dehydrogenase ADHC |
| M. gilvum PYR-GCK | Mflv_4279 | - | 1e-155 | 76.08% (347) | alcohol dehydrogenase |
| M. leprae Br4923 | MLBr_01730 | adhA | 1e-174 | 85.84% (346) | alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3400 | - | 1e-150 | 73.12% (346) | NADP-dependent alcohol dehydrogenase C |
| M. marinum M | MMAR_1649 | adh | 0.0 | 88.73% (346) | NADP-dependent alcohol dehydrogenase Adh |
| M. avium 104 | MAV_3911 | - | 1e-169 | 83.53% (346) | NADP-dependent alcohol dehydrogenase c |
| M. smegmatis MC2 155 | MSMEG_2317 | - | 1e-160 | 79.83% (347) | alcohol dehydrogenase, zinc-containing |
| M. thermoresistible (build 8) | TH_4581 | - | 1e-159 | 78.32% (346) | PUTATIVE alcohol dehydrogenase, zinc-containing |
| M. ulcerans Agy99 | MUL_1885 | adh | 0.0 | 88.73% (346) | NADP-dependent alcohol dehydrogenase Adh |
| M. vanbaalenii PYR-1 | Mvan_2080 | - | 1e-154 | 76.37% (347) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4279|M.gilvum_PYR-GCK ----------------MSTVSAYAATSATEPLTKTTITRREVGPHDVAFD
Mvan_2080|M.vanbaalenii_PYR-1 ----------------MTTVSAYAATSADGPLTRTTVTRRDVGPHDVAFD
MSMEG_2317|M.smegmatis_MC2_155 ----------------MSTVSAYAATSATEPLTKTTITRRAVGPHDVAFD
TH_4581|M.thermoresistible__bu ----------------MTTVSAYAATSVSEPLTRTTITRREMGPHDVTIA
Rv3045|M.tuberculosis_H37Rv ----------------MSTVAAYAAMSATEPLTKTTITRRDPGPHDVAID
Mb3071|M.bovis_AF2122/97 ----------------MSTVAAYAAMSATEPLTKTTITRRDPGPHDVAID
MMAR_1649|M.marinum_M ----------------MNTVSAYAALSATEPLTKTTITRRDPGPHDVAID
MUL_1885|M.ulcerans_Agy99 ----------------MNTVSAYAALSATEPLTKTTITRRDPGPHDVAID
MLBr_01730|M.leprae_Br4923 MKSHVSKHRRKRRLGAMTTVSAYAATSATEPLTKVTINRRAPGPHDVAIQ
MAV_3911|M.avium_104 ----------------MSTVSAYAATSATEPLTKTTIERRDPGPRDVAID
MAB_3400|M.abscessus_ATCC_1997 ----------------MVTVSAYAATSGKDPLVPTTIERREVGPHDVFID
* **:**** * **. .*: ** **:** :
Mflv_4279|M.gilvum_PYR-GCK IHFAGICHSDVHTVRAEWGQPAYPVVPGHEIAGIVTEVGPEVTRYKVGDR
Mvan_2080|M.vanbaalenii_PYR-1 IHFAGICHSDIHTVRGEWGGIDYPLVPGHEIAGIVTEVGSAVTKFTVGDR
MSMEG_2317|M.smegmatis_MC2_155 IHFAGICHSDIHTVKAEWGVPNYPVVPGHEIAGVVTEVGSEVTKYKVGDR
TH_4581|M.thermoresistible__bu IHFAGICHSDIHTVKGEWGEPAFPLVPGHEIAGVVTAVGSEVTRYRVGDR
Rv3045|M.tuberculosis_H37Rv IKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGSEVTKYRQGDR
Mb3071|M.bovis_AF2122/97 IKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGSEVTKYRQGDR
MMAR_1649|M.marinum_M IKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVSAVGSQVTKHKVGDH
MUL_1885|M.ulcerans_Agy99 IKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVSAVGSQVTKHKVGDH
MLBr_01730|M.leprae_Br4923 IKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGTEVTKHKVGDR
MAV_3911|M.avium_104 IKFAGICHSDIHTAKGEWGHTNYPVVVGHEIAGVVTEVGAEVTKYKVGDH
MAB_3400|M.abscessus_ATCC_1997 IKFAGICHSDIHTVRDEWGRANYPIVPGHEIAGVITEVGSEVTKFKPGDH
*:********:**.: *** :*:* ******::: **. **:. **:
Mflv_4279|M.gilvum_PYR-GCK VGVGCFVDSCRECEECRAGEQQYCTGGGMVGTYNGVGRDGEPTQGGYSGA
Mvan_2080|M.vanbaalenii_PYR-1 VGVGCFVDSCRECDACRDGEEQYCTGGGMVGTYNGVGRDGQRTQGGYSGA
MSMEG_2317|M.smegmatis_MC2_155 VGVGCFVDSCRECDNCKAGLEQYCTGTGMVGTYNAIDRDGTPTHGGYSGA
TH_4581|M.thermoresistible__bu VGVGCFVDSCRECRHCLAGDEQYCVR-GMTGTYNGVDRDGRPTQGGYSGA
Rv3045|M.tuberculosis_H37Rv VGVGCFVDSCRECNSCTRGIEQYCKP-GANFTYNSIGKDGQPTQGGYSEA
Mb3071|M.bovis_AF2122/97 VGVGCFVDSCRECNSCTRGIEQYCKP-GANFTYNSIGKDGQPTQGGYSEA
MMAR_1649|M.marinum_M VGVGCFVDSCRECSCCERGIEQYCKR-GATFTYNSVGKDGQPTQGGYSKA
MUL_1885|M.ulcerans_Agy99 VGVGCFVDSCRECSCCERGIEQYCKR-GATFTYNSVGKDGQPTQGGYSKA
MLBr_01730|M.leprae_Br4923 VGVGCMVGSCGECSSCLAGIEQYCKR-GATFTYNSIGTDGQSTQGGYSQA
MAV_3911|M.avium_104 VGVGCMVNSCRQCSSCTAGLEQYCKR-GATFTYNSIDRDGSVTQGGYSQA
MAB_3400|M.abscessus_ATCC_1997 AGVGCFVNSCRECPSCLAGLEQFCER-GMVGTYGAKDRDGTQTQGGYSQA
.****:*.** :* * * :*:* * **.. . ** *:**** *
Mflv_4279|M.gilvum_PYR-GCK IVVDENYVLRIPDSISLDKAAPLLCAGITTYSPLHHWNAGPGKKIAVIGL
Mvan_2080|M.vanbaalenii_PYR-1 IVVDENYVLNIPDAIPLDKAAPLLCAGITTYSPLHHWNAGPGTKVAVIGL
MSMEG_2317|M.smegmatis_MC2_155 IVVDENYVLRIPDSLPLDAAAPLLCAGITTYSPLRHWNAGPGKKVAVIGL
TH_4581|M.thermoresistible__bu IVVDENYVLRIPDSLPLDAAAPLLCAGITTYSPLRHWNVGPGTRVAVVGL
Rv3045|M.tuberculosis_H37Rv IVVDENYVLRIPDVLPLDVAAPLLCAGITLYSPLRHWNAGANTRVAIIGL
Mb3071|M.bovis_AF2122/97 IVVDENYVLRIPDVLPLDVAAPLLCAGITLYSPLRHWNAGANTRVAIIGL
MMAR_1649|M.marinum_M IVVDESYVLRIPDALPLDAAAPLLCAGITLFSPLRHWNAGPGKRIAVIGL
MUL_1885|M.ulcerans_Agy99 IVVDESYVLRIPDALPLDAAAPLLCAGITLFSPLRHWNAGPGKRIAVIGL
MLBr_01730|M.leprae_Br4923 IVVDENFVVHIPDALPLDAAAPLLCAGITLYSPLRHWNAKPGTRLAIIGL
MAV_3911|M.avium_104 IVVDEDFVVRIPDSLPLDKAAPLLCAGITLFSPLRHWKAGPGTRLAIVGL
MAB_3400|M.abscessus_ATCC_1997 IVVDENYVLRIPDSLPLDAAAPLLCAGITTFSPLRHWNAGPGKRVAVVGL
*****.:*:.*** :.** ********** :***:**:. ...::*::**
Mflv_4279|M.gilvum_PYR-GCK GGLGHLAVKIAVAMGAEVTVLSQSLKKMEDGLRLGATDYRATSDRDTFKD
Mvan_2080|M.vanbaalenii_PYR-1 GGLGHLAVKLAAAMGAEVTVLSQSLKKMEDGLRLGATEYRATSDRDTFKE
MSMEG_2317|M.smegmatis_MC2_155 GGLGHVAVKLAKAMGADVTVLSQSLKKMEDGLRLGASAYYATSDPETFDK
TH_4581|M.thermoresistible__bu GGLGHMAVKLGKALGADVTVLSQSLKKREDGLRLGAGAYYATSDPDTFRA
Rv3045|M.tuberculosis_H37Rv GGLGHMGVKLGAAMGADVTVLSQSLKKMEDGLRLGAKSYYATADPDTFRK
Mb3071|M.bovis_AF2122/97 GGLGHMGVKLGAAMGADVTVLSQSLKKMEDGLRLGAKSYYATADPDTFRK
MMAR_1649|M.marinum_M GGLGHMGVKLATAMGAEVTVLSQSLKKMEDGLRLGASHYYATSDPDTFRK
MUL_1885|M.ulcerans_Agy99 GGLGHMGVKLATAMGAEVTVLSQSLKKMEDGLRLGASHYYATSDPDTFRK
MLBr_01730|M.leprae_Br4923 GGLGHMGVKLGRKMGCEVTVLSQSLKKMEDGLQLGASNYYATADPDTFRK
MAV_3911|M.avium_104 GGLGHMGVKLGAAMGAEVTVLSQSLKKMEDGLRLGAKHYHATADPDTFTK
MAB_3400|M.abscessus_ATCC_1997 GGLGHMAVKLGKAMGAEVTVLSQSLKKMEDGLRLGASHYYATADPDTFKS
*****:.**:. :*.:********** ****:*** * **:* :**
Mflv_4279|M.gilvum_PYR-GCK LKGTFDLIINTVSANLDLSDYLKLLKLDGTLVELGMPEHPMEVPAGALIF
Mvan_2080|M.vanbaalenii_PYR-1 LRGRFDLILNTVSANLNLEDYLKLLKIDGTLVELGMPEHPMSVPAGALIS
MSMEG_2317|M.smegmatis_MC2_155 LAGSFDLILNTVSANLDLGAYLGLLKLDGALVELGLPEHPMEVPAFPLLA
TH_4581|M.thermoresistible__bu LRSSFDVVINTVSANLDLGRYLMLLDVDGTLVELGMPEKPMTVPAAPLVG
Rv3045|M.tuberculosis_H37Rv LRGGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAVPAFALAL
Mb3071|M.bovis_AF2122/97 LRGGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAVPAFALAL
MMAR_1649|M.marinum_M LRGSFDLILNTVSANLDMGQYLNLLDVDGTLVELGIPEHPMEVPAFALAL
MUL_1885|M.ulcerans_Agy99 LRGSFDLILNTVSANLDMGQYLNLLDVDGTLVELGIPEHPMEVPAFALAL
MLBr_01730|M.leprae_Br4923 LRGSFDLILNTVSANLDLGKYLNLLDVNGTLVELGIPEHPMLVPAFALAL
MAV_3911|M.avium_104 LRGSFDLMLNTVSANLKLNDYLSLLDVDGTLVELGIPEHPMEVGAFPLAL
MAB_3400|M.abscessus_ATCC_1997 LRNSFDLILNTVSSNLDMGKYLGLLGVDGTLVELGLPENPIEVPGFPLLT
* . **:::****:**.: ** ** ::*:*****:**:*: * . .*
Mflv_4279|M.gilvum_PYR-GCK GRRSIAGSLIGGIAETQEMLDFCAEHDVTPEIEVVAPDYINEAYERMLAS
Mvan_2080|M.vanbaalenii_PYR-1 GRRSIAGSMIGGIAETQEMLDFCAEHDVTPEIEIIEPDYINEAYERVMAS
MSMEG_2317|M.smegmatis_MC2_155 QRRNLTGSMIGGIPETQEMLDFCAEHDVRPEIEIITPDYINEAYERVLAS
TH_4581|M.thermoresistible__bu GRRRLAGSLIGGIAETQEMLDFCAEHGVLPEIEVIEPEYINTAYERVLAS
Rv3045|M.tuberculosis_H37Rv MRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDAYERVLAS
Mb3071|M.bovis_AF2122/97 MRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDAYERVLAS
MMAR_1649|M.marinum_M MRRSLSGSNIGGIAETQEMLDFCAEHGVTPEIELIEPDYINEAYERVLAS
MUL_1885|M.ulcerans_Agy99 MRRSLSGSNIGGIAETQEMLDFCAEHGVTPEIELIEPDYINEAYERVLAS
MLBr_01730|M.leprae_Br4923 MRRSLAGSNIGGITETQEMMNFSAEHSVTPEIELIEPDYINEAYERVLAS
MAV_3911|M.avium_104 ARRSLSGSNIGGIAETQEMLDFCAEHNVTPEIELIEPDYINEAYERVLAS
MAB_3400|M.abscessus_ATCC_1997 NRRSISGSLIGGIPETQEMLDFCAKHGIGSEIEVIDASYINEAYERVVAS
** ::** ****.*****::*.*:*.: .***:: ..*** ****::**
Mflv_4279|M.gilvum_PYR-GCK DVRYRFVIDTASLR-
Mvan_2080|M.vanbaalenii_PYR-1 DVRYRFVIDTASLR-
MSMEG_2317|M.smegmatis_MC2_155 DVRYRFVIDTASLRS
TH_4581|M.thermoresistible__bu DVRYRFVIDTASLRG
Rv3045|M.tuberculosis_H37Rv DVRYRFVIDISAL--
Mb3071|M.bovis_AF2122/97 DVRYRFVIDISAL--
MMAR_1649|M.marinum_M DVRYRFVIDTSSL--
MUL_1885|M.ulcerans_Agy99 DVRYRFVIDTSSL--
MLBr_01730|M.leprae_Br4923 DVRYRFVINISSL--
MAV_3911|M.avium_104 DVRYRFVIDISKL--
MAB_3400|M.abscessus_ATCC_1997 DVRYRFVIDTQTL--
********: *