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NAGPDTHEPDPYIRVYASRVHNLKTVDVAAPRDSFVAFTGVSGSGKSSLAFGTIYAEAQRRYFESVAPYA RRLLLPQDAPKVDDITGLPPAVALQQRRGTATSRSTVGTVTTLSNLLRMLFSRAGTYPPGATERLDSDAF SPNTTIGACPQCHGLGRIHEVTEETLVPDPSLTIREGAVAAWPGAWQGQNLRDILITLGYDIDKPWRKLP KRQREWILFTEDQPTVEIDPSQHPVTADYYYNGTFSSAERHVRHTLANSQSAAMRRRVLQYVNSVDCHVC DGSGLRPEALAVTFAGRTIADLVALPLTTLAEVLTPAATRTEFAAAYESTESGEFTEVATMIAADLVARI GVLVDLGLGYLSLNRRTPSVSPGELQRLRLATQLRAGLFGVLYVLDEPSAGLHPADAEPLLDVLDRLRRA GNSLFVVEHDMDVVRRADWVVDVGPGAGEWGGEVLYSGPVAGLADVESSVTRRYLFTDGAQADRSTRTPV GVMRLRGITFHNLHDVDVDIPLGAFVAVTGVSGSGKSTLVCKVLGDVMARQLGKSVETPDDAGDGEAELL DIDVDASMGVSVEGAEIIDRLVTVDQRPIGRTPRSNLATYTGLFDAVRKAFADTPEARKRGWSAGRFSFN VAEGRCATCQGEGFVAVELLFLPGTYATCPACGGARYSDETLEVTYRGRTIADVLAQTVDEAAEFLSDLP GAARSLTTLREVGLGYLRLGQPATELSGGEAQRIKLASELQRAKRGHTLYVLDEPTTGLHPADVELLERQ LHRLVDAGNTVVVAEHDMSVVARADHVVDLGPGGGDDGGTVVAAGTPEVVAACTASRTAPYLAARLAGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6806 | uvrA | - | 100% (840) | excinuclease ABC, A subunit |
| M. smegmatis MC2 155 | MSMEG_3808 | uvrA | e-161 | 44.04% (722) | excinuclease ABC subunit A |
| M. smegmatis MC2 155 | MSMEG_0211 | - | e-132 | 38.11% (858) | ABC transporter, ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1664 | uvrA | 1e-167 | 45.17% (715) | excinuclease ABC subunit A |
| M. gilvum PYR-GCK | Mflv_0951 | - | 0.0 | 92.30% (831) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1638 | uvrA | 1e-167 | 45.17% (715) | excinuclease ABC subunit A |
| M. leprae Br4923 | MLBr_01392 | uvrA | 1e-163 | 44.21% (717) | excinuclease ABC subunit A |
| M. abscessus ATCC 19977 | MAB_2315 | uvrA | 1e-162 | 44.26% (723) | excinuclease ABC subunit A |
| M. marinum M | MMAR_2443 | uvrA | 1e-167 | 44.94% (721) | excinuclease ABC (subunit A-DNA-binding ATPase) UvrA |
| M. avium 104 | MAV_3135 | uvrA | 1e-166 | 45.03% (715) | excinuclease ABC subunit A |
| M. thermoresistible (build 8) | TH_1581 | uvrA | 1e-165 | 45.33% (717) | excinuclease ABC, A subunit |
| M. ulcerans Agy99 | MUL_1622 | uvrA | 1e-166 | 44.94% (721) | excinuclease ABC subunit A |
| M. vanbaalenii PYR-1 | Mvan_3339 | uvrA | 1e-166 | 45.38% (725) | excinuclease ABC subunit A |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1664|M.bovis_AF2122/97 ---------MADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSL
Rv1638|M.tuberculosis_H37Rv ---------MADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSL
MMAR_2443|M.marinum_M ---------MADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSL
MUL_1622|M.ulcerans_Agy99 ---------MADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSL
MAV_3135|M.avium_104 ---------MADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSL
MLBr_01392|M.leprae_Br4923 ---------MADRLIVKGAREHNLRSVDLDLPRDSLIVFTGLSGSGKSSL
TH_1581|M.thermoresistible__bu ---------LADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSL
Mvan_3339|M.vanbaalenii_PYR-1 ---------MADRLVVKGAREHNLRGVDLDLPRDAMIVFTGLSGSGKSSL
MAB_2315|M.abscessus_ATCC_1997 ---------MADRLIVRGAREHNLRGIDLDLPRDSLIVFTGLSGSGKSSL
MSMEG_6806|M.smegmatis_MC2_155 MNAGPDTHEPDPYIRVYASRVHNLKTVDVAAPRDSFVAFTGVSGSGKSSL
Mflv_0951|M.gilvum_PYR-GCK -----MTGEPDPYIRVFASRVHNLKTVDVAAPRDSFVAFTGVSGSGKSSL
: * .:* ***: :*: ***:::.***:********
Mb1664|M.bovis_AF2122/97 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
Rv1638|M.tuberculosis_H37Rv AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MMAR_2443|M.marinum_M AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MUL_1622|M.ulcerans_Agy99 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MAV_3135|M.avium_104 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MLBr_01392|M.leprae_Br4923 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
TH_1581|M.thermoresistible__bu AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
Mvan_3339|M.vanbaalenii_PYR-1 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MAB_2315|M.abscessus_ATCC_1997 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MSMEG_6806|M.smegmatis_MC2_155 AFGTIYAEAQRRYFESVAPYARRLLLPQDAPKVDDITGLPPAVALQQRRG
Mflv_0951|M.gilvum_PYR-GCK AFGTIYAEAQRRYFESVAPYARRLLLPQDAPKVDDITGLPPAVALQQRRG
**.**:**.****.**::.***::* * *.** * **.***:::*:
Mb1664|M.bovis_AF2122/97 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVL
Rv1638|M.tuberculosis_H37Rv NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVL
MMAR_2443|M.marinum_M NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVL
MUL_1622|M.ulcerans_Agy99 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVL
MAV_3135|M.avium_104 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVL
MLBr_01392|M.leprae_Br4923 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPICGEQISRQTPQQIVDQVL
TH_1581|M.thermoresistible__bu NRNPRSTVGTITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVL
Mvan_3339|M.vanbaalenii_PYR-1 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVL
MAB_2315|M.abscessus_ATCC_1997 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPVCGEKIAKQTPQQIVDQVL
MSMEG_6806|M.smegmatis_MC2_155 TATSRSTVGTVTTLSNLLRMLFSRAGT-----------------------
Mflv_0951|M.gilvum_PYR-GCK TATSRSTVGTVTTLSNLVRMLFSRAGT-----------------------
. ..******:* : : :*:*::****
Mb1664|M.bovis_AF2122/97 AMPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
Rv1638|M.tuberculosis_H37Rv AMPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
MMAR_2443|M.marinum_M AMAEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
MUL_1622|M.ulcerans_Agy99 AMAEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
MAV_3135|M.avium_104 AMPEGTRFLVLAPVVRTRKGEFADLFEKLNAQGYSRVRVDGVVHPLTDPP
MLBr_01392|M.leprae_Br4923 VLPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDDVVYPLSDPP
TH_1581|M.thermoresistible__bu AMDEGLRFQVLAPVVRTRKGEFVDLFDKLNSQGYSRVRVDGVVYPLTDPP
Mvan_3339|M.vanbaalenii_PYR-1 AMDEGLRFQVLAPVVRTRKGEFVDLFDKLNSQGYSRVRVDGVVHPLTDPP
MAB_2315|M.abscessus_ATCC_1997 DMEEGLRFQVLAPVVRTRKGEFVDLFEQLNSQGYSRIRVDGVVHSLTDPP
MSMEG_6806|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0951|M.gilvum_PYR-GCK --------------------------------------------------
Mb1664|M.bovis_AF2122/97 KLKKQEKHDIEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-H
Rv1638|M.tuberculosis_H37Rv KLKKQEKHDIEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-H
MMAR_2443|M.marinum_M KLKKQEKHDIEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDH
MUL_1622|M.ulcerans_Agy99 KLKKQEKHDIEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDH
MAV_3135|M.avium_104 KLKKQEKHDIEVVVDRLTVKASAKQRLTDSVETALNLADGIVVLEFVD-H
MLBr_01392|M.leprae_Br4923 KLKKQEKHDIEVVVDRLTVKIAAKQRLTDSVETALNLADGIVVLEFPDDH
TH_1581|M.thermoresistible__bu KLKKQEKHDIEVVVDRLTVKPSAKQRLTDSIETALNLADGIVVLDFVD-R
Mvan_3339|M.vanbaalenii_PYR-1 KLKKQEKHDIEVVVDRLTVKATAKQRLTDSVETALNLADGIVVLEFVD-R
MAB_2315|M.abscessus_ATCC_1997 KLKKQEKHDIEVVIDRLSVKASSKQRLTDSVETALHLADGIVVLEFVD-A
MSMEG_6806|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0951|M.gilvum_PYR-GCK --------------------------------------------------
Mb1664|M.bovis_AF2122/97 ELGAPHREQRFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGI
Rv1638|M.tuberculosis_H37Rv ELGAPHREQRFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGI
MMAR_2443|M.marinum_M DEHDHPREQRFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECSGLGI
MUL_1622|M.ulcerans_Agy99 DEHDHPREQRFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECSGLGI
MAV_3135|M.avium_104 EHDAHNREQRFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGI
MLBr_01392|M.leprae_Br4923 DERGHPREQCFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECVGLGI
TH_1581|M.thermoresistible__bu DEDDPHREQRFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECAGLGI
Mvan_3339|M.vanbaalenii_PYR-1 EDDHPHREQRFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECTGLGI
MAB_2315|M.abscessus_ATCC_1997 DEDSPQRERRFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECAGLGI
MSMEG_6806|M.smegmatis_MC2_155 ----------------YPPG---ATERLDSDAFSPNTTIGACPQCHGLGR
Mflv_0951|M.gilvum_PYR-GCK ----------------YPPG---ATERLDSDAFSPNTTIGACPQCHGLGR
* * *.: *:. :** *:. ****:* ***
Mb1664|M.bovis_AF2122/97 RKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVD
Rv1638|M.tuberculosis_H37Rv RKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVD
MMAR_2443|M.marinum_M RKEVDPDLVVPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALGFDVD
MUL_1622|M.ulcerans_Agy99 RKEVDPDLVVPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALGFDVD
MAV_3135|M.avium_104 RKEVDPDLVVPDPERTLAEGAVAPWSTGHTAEYFTRMMAGLGDELGFDVD
MLBr_01392|M.leprae_Br4923 RKEIDSDLVVPDPDRTLAEGAVAPWSAGRTAEYFTRMMAGLGEKLGFDVD
TH_1581|M.thermoresistible__bu RKEVDVDLVVPDPDLTLAEGAIAPWSMGQTAEYFTRMLAGLGEAMGFDVD
Mvan_3339|M.vanbaalenii_PYR-1 RKEVDPDLVVPDPDLTLAEGAIAPWSMGHTAEYFTRMLSGLGDQLGFDVN
MAB_2315|M.abscessus_ATCC_1997 KKEVDPDLVVPDPDMTLAEGAIAPWSMGQNADYFVRLMAGLGDALGFDVD
MSMEG_6806|M.smegmatis_MC2_155 IHEVTEETLVPDPSLTIREGAVAAWPGAWQGQNLRDILITLG----YDID
Mflv_0951|M.gilvum_PYR-GCK IHEVTEETLVPDPSLSIRDGAVAAWPGAWQGQNLRDILITLG----YDID
:*: : :****. :: :**:*.*. . .: : :: ** :*::
Mb1664|M.bovis_AF2122/97 TPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVLAFLQ
Rv1638|M.tuberculosis_H37Rv TPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVLAFLQ
MMAR_2443|M.marinum_M TPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVLAFLQ
MUL_1622|M.ulcerans_Agy99 TPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVLAFLQ
MAV_3135|M.avium_104 TPWRKLPAKARKAILEGSDHQVHVRYRNRYGRTRSYYAD--FEGVLAFLQ
MLBr_01392|M.leprae_Br4923 TPWRKLPAKARKAILEGSDHQVHVQYHNRYGRPRSYYVD--FEGVLTFLQ
TH_1581|M.thermoresistible__bu TPWRKLPAKVRKAILEGCDEQVHVRYKNRYGRVRSYYAD--FEGVMAYLH
Mvan_3339|M.vanbaalenii_PYR-1 TPWKKLPAKARRAILEGCDEQVHVRYKNRYGRTRSYYAD--FEGVMAFLQ
MAB_2315|M.abscessus_ATCC_1997 TPWKKLPAAAKKAILDGSSEQVHVRYKNRYGRTRSYYAE--FEGVLAFLQ
MSMEG_6806|M.smegmatis_MC2_155 KPWRKLPKRQREWILFTEDQPTVEIDPSQHPVTADYYYNGTFSSAERHVR
Mflv_0951|M.gilvum_PYR-GCK KPWRKLTKRQRDWVLFTEDQPTVEIDPSRHPVTADYYYNGTFSSAERHVR
.**:**. : :* .. . .:: .** : *... .::
Mb1664|M.bovis_AF2122/97 RKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESKGEHG
Rv1638|M.tuberculosis_H37Rv RKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESKGEHG
MMAR_2443|M.marinum_M RKMAQTESEQMKERYEGFMRDVPCPVCDGARLKPEILSVTLAA---GEQD
MUL_1622|M.ulcerans_Agy99 RKMAQTESEQMKERYEGFMRDVPCPVCDGARLKPEILSVTLAA---GEQD
MAV_3135|M.avium_104 RKMAQTESEQMKERYEGFMRDVPCPVCEGTRLKPEILAVTLAA---GRHG
MLBr_01392|M.leprae_Br4923 RKMEQTESEQMKERYEGFMRNIPCPVCQGTRLKPEILAVTLAA---GERG
TH_1581|M.thermoresistible__bu RRMEQTDSEQMKERLEGFMRDVPCPECGGTRLKPEILAVTLSA---GEFG
Mvan_3339|M.vanbaalenii_PYR-1 RRMEQTDSEQMKERLEGFMRDVPCPECDGTRLKPEILAVTMTA---GNFG
MAB_2315|M.abscessus_ATCC_1997 RRMEQTESEWAKERYEGFMRDIPCPVCEGTRLKPEILSVTLTA---GEHG
MSMEG_6806|M.smegmatis_MC2_155 HTLANSQSAAMRRRVLQYVNSVDCHVCDGSGLRPEALAVTFAGRTIADLV
Mflv_0951|M.gilvum_PYR-GCK HTLANSQSAAMRRRVLQYVHSTDCPVCGGSGLRAEALAVTFAGRTIAELV
: : :::* :.* ::.. * * *: *:.* *:**::. .
Mb1664|M.bovis_AF2122/97 AKSIAEVCELSIADCADFLNALTLGPREQ----AIAGQVLKEIRSRLGFL
Rv1638|M.tuberculosis_H37Rv AKSIAEVCELSIADCADFLNALTLGPREQ----AIAGQVLKEIRSRLGFL
MMAR_2443|M.marinum_M AKSIAEVCELSISDCADFLNALTLGAREQ----AIAGQVLKEIQSRLGFL
MUL_1622|M.ulcerans_Agy99 AKSIAEVCELSISDCADFLNALTLGAREQ----AIAGQVLKEIQSRLGFL
MAV_3135|M.avium_104 KKSIAEVCELSISDCAEFLNTLTLGPREQ----AIAGQVLKEIQSRLGFL
MLBr_01392|M.leprae_Br4923 AKSIAEVCELSIADCSAFLNALILGVREQ----AIAGQVLKEIQSRLGFL
TH_1581|M.thermoresistible__bu EKSIAEVADLSIADCAEFLNALTLGPREQ----AIAGQVLKEIQSRLGFL
Mvan_3339|M.vanbaalenii_PYR-1 AKSIAEVAELSIADCAEFLNALTLGTREA----AIAGQVLKEIQSRLGFL
MAB_2315|M.abscessus_ATCC_1997 TKSIAEVCDLSIADCAQFLGALTLGHREQ----AIAGQVLKEVQFRLGFL
MSMEG_6806|M.smegmatis_MC2_155 ALPLTTLAEVLTPAATRTEFAAAYESTESGEFTEVATMIAADLVARIGVL
Mflv_0951|M.gilvum_PYR-GCK ALPLTTLAEVLEPAATRTEFAAAYESTESGEFTEVATMIAADLVARIGVL
.:: :.:: . .: : * :* : :: *:*.*
Mb1664|M.bovis_AF2122/97 LDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
Rv1638|M.tuberculosis_H37Rv LDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
MMAR_2443|M.marinum_M LDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
MUL_1622|M.ulcerans_Agy99 LDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
MAV_3135|M.avium_104 LDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
MLBr_01392|M.leprae_Br4923 LDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
TH_1581|M.thermoresistible__bu LDVGLDYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
Mvan_3339|M.vanbaalenii_PYR-1 LDVGLDYLSLSRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
MAB_2315|M.abscessus_ATCC_1997 LDVGLQYLSLSRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
MSMEG_6806|M.smegmatis_MC2_155 VDLGLGYLSLNRRTPSVSPGELQRLRLATQLRAGLFGVLYVLDEPSAGLH
Mflv_0951|M.gilvum_PYR-GCK VDLGLGYLSLHRRTPTVSPGELQRLRLATQLRAGLFGVLYVLDEPSAGLH
:*:** **** * : ::* ** **:*****: :**.********** ***
Mb1664|M.bovis_AF2122/97 QRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGR
Rv1638|M.tuberculosis_H37Rv QRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGR
MMAR_2443|M.marinum_M QRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWVVDIGPGAGEHGGS
MUL_1622|M.ulcerans_Agy99 QRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWVVDIGPGAGEHGGS
MAV_3135|M.avium_104 QRDNRRLIETLTRLRDLGNTLIVVEHDEDTIAHADWIVDIGPRAGEHGGQ
MLBr_01392|M.leprae_Br4923 QRDNRRLIETLTRLRALGNTLIVVEHDEDTIAHADWVVDIGPGAGEHGGQ
TH_1581|M.thermoresistible__bu QRDNRRLIDTLVRLRDLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGR
Mvan_3339|M.vanbaalenii_PYR-1 QRDNRRLIDTLVRLRDLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGQ
MAB_2315|M.abscessus_ATCC_1997 QRDNRRLIETLTRLRDLGNTLIVVEHDEDTIKHADWVVDIGPAAGEHGGQ
MSMEG_6806|M.smegmatis_MC2_155 PADAEPLLDVLDRLRRAGNSLFVVEHDMDVVRRADWVVDVGPGAGEWGGE
Mflv_0951|M.gilvum_PYR-GCK PADAEPLLEVLDRLRRAGNSLFVVEHDMDVVRRADWVVDVGPGAGELGGD
* . *::.* *** **:*:***** *.: :***:**:** *** **
Mb1664|M.bovis_AF2122/97 IVHSGPYDELLRNKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVVGARE
Rv1638|M.tuberculosis_H37Rv IVHSGPYDELLRNKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVVGARE
MMAR_2443|M.marinum_M IVHSGPYQELLRNQSSITGAFLSGREGIEIPTSRRSVDSRRQLTVVGARE
MUL_1622|M.ulcerans_Agy99 IVHSGPYQELLRNQSSITGAFLSGREGIEIPTSRRSIDSRRQLTVVGARE
MAV_3135|M.avium_104 IVHSGTYAELLANQDSITGAYLSGKESIEMPAIRRPVDRRRQLTVVGARE
MLBr_01392|M.leprae_Br4923 IVHNGTYRELLANKDSITGAYLSGRESIATPTRRRSVDRKRELTVVGARE
TH_1581|M.thermoresistible__bu IVHSGPYADLLANPDSLTGEYLSGKKSIEVPAMRRPVDRKRQLTVVGARE
Mvan_3339|M.vanbaalenii_PYR-1 IVHSGTYEDLLRNPNSITGAYLSGKEEIEVPDMRRVVDRKRQLTVVGARE
MAB_2315|M.abscessus_ATCC_1997 VVHSGTYAELLKNKNSVTGSYLSGAESIPLPLIRRVIDPKRQVTVVGARE
MSMEG_6806|M.smegmatis_MC2_155 VLYSGPVAGLADVESSVTRRYLFTDGAQADRSTRTPVGVMR---LRGITF
Mflv_0951|M.gilvum_PYR-GCK VLYSGPVAGLANVDASVTRRFLFAEEARPARAPRTPASVMR---LRGITF
:::.*. * *:* :* * . * : *
Mb1664|M.bovis_AF2122/97 HNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPG
Rv1638|M.tuberculosis_H37Rv HNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPG
MMAR_2443|M.marinum_M HNLRGIDVAFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPG
MUL_1622|M.ulcerans_Agy99 HNLRGLDVAFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPG
MAV_3135|M.avium_104 HNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILATVLANRLNGARLVPG
MLBr_01392|M.leprae_Br4923 HNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPG
TH_1581|M.thermoresistible__bu NNLRDIDVSFPLGVLTAVTGVSGSGKSTLVNDILAAALANKLNGARLVPG
Mvan_3339|M.vanbaalenii_PYR-1 HNLREIDVAFPLGVLTSVTGVSGSGKSTLVNDILASVLANKLNGARLVPG
MAB_2315|M.abscessus_ATCC_1997 HNLKDIDVSFPLGVLTSVTGVSGSGKSTLVNDILATVLANKLNGARQVPG
MSMEG_6806|M.smegmatis_MC2_155 HNLHDVDVDIPLGAFVAVTGVSGSGKSTLVCKVLGDVMARQLGKSVETPD
Mflv_0951|M.gilvum_PYR-GCK HNLVGVDVDIPLGSFVAVTGVSGSGKSTLVCKVLGDVMARQLGRSPEPAE
:** :** :*** :.:************* .:*. .:*.:*. : .
Mb1664|M.bovis_AF2122/97 RHTR-----------------VTGLDYLDKLVRVDQSPIGRTPRSNPATY
Rv1638|M.tuberculosis_H37Rv RHTR-----------------VTGLDYLDKLVRVDQSPIGRTPRSNPATY
MMAR_2443|M.marinum_M RHTR-----------------ITGLDHLDKLVRVDQSPIGRTPRSNPATY
MUL_1622|M.ulcerans_Agy99 RHTR-----------------ITGLDHLDKLVRVDQSPIGRTPRSNPATY
MAV_3135|M.avium_104 RHTR-----------------VTGLDHLDKLVRVDQSPIGRTPRSNPATY
MLBr_01392|M.leprae_Br4923 RHTR-----------------VTGLEHLDKLVRVDQSPIGRTPRSNPATY
TH_1581|M.thermoresistible__bu RHTR-----------------VNGLGEVDKLVRVDQSPIGRTPRSNPATY
Mvan_3339|M.vanbaalenii_PYR-1 RHTR-----------------VNGLDHLDKLVRVDQSPIGRTPRSNPATY
MAB_2315|M.abscessus_ATCC_1997 RHTR-----------------VTGLDKVDKLVRVDQSPIGRTPRSNPATY
MSMEG_6806|M.smegmatis_MC2_155 DAGDGEAELLDIDVDASMGVSVEGAEIIDRLVTVDQRPIGRTPRSNLATY
Mflv_0951|M.gilvum_PYR-GCK DAADGDAELLDIDVDSSVGVAVEGAEIIDRLVTVDQRPIGRTPRSNLATY
: * :*:** *** ********* ***
Mb1664|M.bovis_AF2122/97 TGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMN
Rv1638|M.tuberculosis_H37Rv TGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMN
MMAR_2443|M.marinum_M TGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMN
MUL_1622|M.ulcerans_Agy99 TGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMN
MAV_3135|M.avium_104 TGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMN
MLBr_01392|M.leprae_Br4923 TGVFDKIRILFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMN
TH_1581|M.thermoresistible__bu TGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACSGDGTLKIEMN
Mvan_3339|M.vanbaalenii_PYR-1 TGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACSGDGTIKIEMN
MAB_2315|M.abscessus_ATCC_1997 TGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMN
MSMEG_6806|M.smegmatis_MC2_155 TGLFDAVRKAFADTPEARKRGWSAGRFSFNVAEGRCATCQGEGFVAVELL
Mflv_0951|M.gilvum_PYR-GCK TGLFDAVRKAFADTPEARRRGWSAGRFSFNVAEGRCATCQGEGFVAVELL
**:** :* ** *.**: **:..******* *** :* *:* : :*:
Mb1664|M.bovis_AF2122/97 FLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFFEPIA
Rv1638|M.tuberculosis_H37Rv FLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFFEPIA
MMAR_2443|M.marinum_M FLPDVYVPCEVCQGARYNRETLEVHYKGKTISEVLDMSIEEAADFFEPIS
MUL_1622|M.ulcerans_Agy99 FLPDVYVPCEVCQGARYNRETLEVHYNGKTISEVLDMSIEEAADFFEPIS
MAV_3135|M.avium_104 FLPDVYVPCEVCHGARYNRETLEVHYKGKTISEVLDMSIEEAAEFFEPIT
MLBr_01392|M.leprae_Br4923 FLPDVYVPCEVCQGARYNRETLEVHYKGKAISEVLDMSIEEAAEFFEPII
TH_1581|M.thermoresistible__bu FLPDVYVPCEVCHGARYNRETLEVHYKGKTIAEVLDMSIEEAAEFFAPIS
Mvan_3339|M.vanbaalenii_PYR-1 FLPDVYVPCEVCQGARYNRETLEVHYKGKTIAEVLDMSIEEAAEFFAPIS
MAB_2315|M.abscessus_ATCC_1997 FLPDVYVPCEVCHGARYNRETLEVHYKGKTIAQVLDMPIEEAAEFFEPIT
MSMEG_6806|M.smegmatis_MC2_155 FLPGTYATCPACGGARYSDETLEVTYRGRTIADVLAQTVDEAAEFLSDLP
Mflv_0951|M.gilvum_PYR-GCK FLPGTYATCPACGGARYSDETLEVTYRDRTIADVLAQTVDEAADFLTELP
***..*..* .* ****. ***** *..:::::** .::***:*: :
Mb1664|M.bovis_AF2122/97 GVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTVY
Rv1638|M.tuberculosis_H37Rv GVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTVY
MMAR_2443|M.marinum_M GIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTIY
MUL_1622|M.ulcerans_Agy99 GIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTIY
MAV_3135|M.avium_104 GIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLAAELQKRSTGRTIY
MLBr_01392|M.leprae_Br4923 GINRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTIY
TH_1581|M.thermoresistible__bu SIHRYLQTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTVY
Mvan_3339|M.vanbaalenii_PYR-1 SIHRYLKTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTIY
MAB_2315|M.abscessus_ATCC_1997 SIHRYLKTLVEVGLGYVRLGQPAPTLSGGEAQRVKLAAELQKRSTGKTIY
MSMEG_6806|M.smegmatis_MC2_155 GAARSLTTLREVGLGYLRLGQPATELSGGEAQRIKLASELQRAKRGHTLY
Mflv_0951|M.gilvum_PYR-GCK GAARSLTTLREVGLGYLRLGQPATELSGGEAQRIKLATELQRAKRGHTLY
. * * ** :*****:******. ********:***:***: . *:*:*
Mb1664|M.bovis_AF2122/97 ILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVIKTSDWIIDL
Rv1638|M.tuberculosis_H37Rv ILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVIKTSDWIIDL
MMAR_2443|M.marinum_M ILDEPTTGLHFDDIRKLLNVISGLVDKGNTVVVIEHNLDVIKTSDWIIDM
MUL_1622|M.ulcerans_Agy99 ILDEPTTGLHFDDIRKLLNVISGLVDKGNTVVVIEHNLDVIKTSDWIIDM
MAV_3135|M.avium_104 ILDEPTTGLHFDDIRKLLKVINGLVDKGNTVIVIEHNLDVIKTSDWIVDM
MLBr_01392|M.leprae_Br4923 ILDEPTTGLHFDDIRKLLNVINGLVDKDNTVIVIEHNLDVIKTSDWIVDM
TH_1581|M.thermoresistible__bu ILDEPTTGLHFEDIRKLLGVINGLVDKGNTVIVIEHNLDVIKTADWIIDM
Mvan_3339|M.vanbaalenii_PYR-1 ILDEPTTGLHFEDIRKLLTVINGLVDKGNTVIVIEHNLDVIKTSDWVVDM
MAB_2315|M.abscessus_ATCC_1997 ILDEPTTGLHFEDIRKLLTVINGLVDKGNTVIVIEHNLDVIKTSDWIIDM
MSMEG_6806|M.smegmatis_MC2_155 VLDEPTTGLHPADVELLERQLHRLVDAGNTVVVAEHDMSVVARADHVVDL
Mflv_0951|M.gilvum_PYR-GCK VLDEPTTGLHPADVELLERQLHRLVEAGNTVVVAEHDMAVVAGADHVIDL
:********* *:. * : **: .***:* **:: *: :* ::*:
Mb1664|M.bovis_AF2122/97 GPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVVG-----GGASAATS
Rv1638|M.tuberculosis_H37Rv GPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVVG-----GGASAATS
MMAR_2443|M.marinum_M GPEGGAGGGTVVAQGAPEDIAAVPESYTGKFLAEVLA-----ARRPSTTA
MUL_1622|M.ulcerans_Agy99 GPEGGAGGGTVVAQGAPEDIAAVPESYTGKFLAEVLA-----ARRPSTTA
MAV_3135|M.avium_104 GPEGGAEGGTVVAQGTPEDVAAVPESYTGKFLAEVIGR----GGAAAGAP
MLBr_01392|M.leprae_Br4923 GPEGGAQGGTVVAEGTPEDVAAVPESYTGKFLAEVVGA----GCAPARTP
TH_1581|M.thermoresistible__bu GPEGGNGGGTVVAQGTPEDVAANPDSYTGQFLAEILD--------VPAPT
Mvan_3339|M.vanbaalenii_PYR-1 GPEGGSGGGTVVATGTPEDVAANPDSYTGHFLAETLG--------VARPK
MAB_2315|M.abscessus_ATCC_1997 GPEGGSGGGTVVAEGTPESVAQTAGSYTGEFLVDLLPRPVRNGKAPAKAP
MSMEG_6806|M.smegmatis_MC2_155 GPGGGDDGGTVVAAGTPEVVAACTASRTAPYLAARLAG--------A---
Mflv_0951|M.gilvum_PYR-GCK GPGGGDDGGTVVAAGTPSVVAAHASSRTAPYLAVQLR-------------
** ** ****** *:*. :* . * *. :*. :
Mb1664|M.bovis_AF2122/97 R-SNRRRNVSA---------
Rv1638|M.tuberculosis_H37Rv R-SNRRRNVSA---------
MMAR_2443|M.marinum_M RRTNRRRKVSA---------
MUL_1622|M.ulcerans_Agy99 RRTNRRRKVSA---------
MAV_3135|M.avium_104 RRSSRRRKATA---------
MLBr_01392|M.leprae_Br4923 R---RRRTVTA---------
TH_1581|M.thermoresistible__bu RK-RRKVQVSA---------
Mvan_3339|M.vanbaalenii_PYR-1 PKSRRRSKVSA---------
MAB_2315|M.abscessus_ATCC_1997 AKSTGKTLAKARTRKVVTPV
MSMEG_6806|M.smegmatis_MC2_155 --------------------
Mflv_0951|M.gilvum_PYR-GCK --------------------