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M. bovis AF2122 / 97 Mb2959 (ppsD)

annotation: phenolpthiocerol synthesis type-I polyketide synthase PPSD
coordinates: 3218821 - 3224304
length: 1827

MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQLLADGVDTIEQ
VPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVAMDPQHRILLEVAWEALEHAG
IPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTGTPHCAAVGRIAYLLGLRGPAVAVDTACSSS
LVAIHLACQSLRLRETDVALAGGVQLTLSPFTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLK
RLADAVRDQDRVLAVVRGSATNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGD
PIEFESLAATYGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDA
SATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALNVSGKTAARVA
SAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAGLRALAAGQPRVGVVDCDQHA
GGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPIFVDQVGFSLQQTLIDGDEVVGIDRIQPVLV
GMQLALTELWRSYGVIPDAVIGHSMGEVSAAVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDAD
AAEALIAGYPQVTLAVHASPRQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSA
LADLTPQPPSIPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDT
LDPDGSHTVMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVTDRSAMSELAATH
PLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEIALAAASEALGTAADAVAPNIVI
NQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTRGGEFCRHATAKVEQSPRECAHAHPEAQGPATG
TTVSPADFYALLRQTGQHHGPAFAALSRIVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAA
IPDGEIAGSAEASYLPVSFETIRVYRDIGRHVRCRAHLTNLDGGTGKMGRIVLINDAGHIAAEVDGIYLR
RVERRAVPLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQQWR
SPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVVFVGGASSRLDDELAAARDTVWSITTVVRAVVGT
WHGRSPRLWLVTGGGLSVADDEPGTPAAASLKGLVRVLAFEHPDMRTTLVDLDITQDPLTALSAELRNAG
SGSRHDDVIAWRGERRFVERLSRATIDVSKGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVVLGG
RSDPTDEQCNVLAELQTRAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLVFSMSRDN
LERVWAPKATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYACASAWLDALVGWRRASGLPAAVIN
WGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPEIRSISYFTQVVEE
LDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQSTVEPAVPLDKPLTELGLDSLMAVR
IRNGARADFGVEPPVALILQGASLHDLTADLMRQLGLNDPDPALNNADTIRDRARQRAAARHGAAMRRRP
KPAVQGG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2959ppsD-100% (1827)phenolpthiocerol synthesis type-I polyketide synthase PPSD
M. bovis AF2122 / 97Mb2958ppsC0.045.57% (1545) phenolpthiocerol synthesis type-I polyketide synthase PPSC
M. bovis AF2122 / 97Mb2957ppsB0.063.30% (932) phenolpthiocerol synthesis type-I polyketide synthase PPSB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3391-0.057.11% (1842) beta-ketoacyl synthase
M. tuberculosis H37RvRv2934ppsD0.099.89% (1827) phenolpthiocerol synthesis type-I polyketide synthase PPSD
M. leprae Br4923MLBr_02354-0.080.23% (1836) polyketide synthase
M. abscessus ATCC 19977MAB_3148c-0.038.38% (1428) polyketide synthase Pks5
M. marinum MMMAR_1773ppsD0.071.45% (1832) phenolpthiocerol synthesis type-I polyketide synthase PpsD
M. avium 104MAV_2370-0.040.24% (1444) mycocerosic acid synthase
M. smegmatis MC2 155MSMEG_4727-0.040.13% (1535) mycocerosic acid synthase
M. thermoresistible (build 8)TH_4621-0.040.63% (1435) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2016ppsD0.071.40% (1832) phenolpthiocerol synthesis type-I polyketide synthase PpsD
M. vanbaalenii PYR-1Mvan_3124-0.058.93% (1843) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


MAV_2370|M.avium_104                ----------------------------------MVPVAVIGMACRLPGA
TH_4621|M.thermoresistible__bu      --------------------------VNIVGDTPVNAVAVIGMACRLPGG
MSMEG_4727|M.smegmatis_MC2_155      -----------------------------MTQNCVAPVAIIGMACRLPGA
MAB_3148c|M.abscessus_ATCC_199      ------------------------------------------MGCRLPGG
Mb2959|M.bovis_AF2122/97            MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGN
Rv2934|M.tuberculosis_H37Rv         MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGN
MLBr_02354|M.leprae_Br4923          MTSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGN
MMAR_1773|M.marinum_M               MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGN
MUL_2016|M.ulcerans_Agy99           MTSLAERAAQMSPKAREVLAHELVRAGTAFPTDIAEPVAVVGIGCRLPGN
Mflv_3391|M.gilvum_PYR-GCK          MKTTFDRISAMSAEQRDKLAEQFEKASRVAG---AEPIAVVGMGCRFPGG
Mvan_3124|M.vanbaalenii_PYR-1       MKTTFDRISAMSAEQRGKLAEQFEKASRVAG---AEPIAVVGIGCRLPGG
                                                                              :.**:** 

MAV_2370|M.avium_104                VDSPERLWEALLRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVSRWGAFI
TH_4621|M.thermoresistible__bu      IDSPQRLWEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFL
MSMEG_4727|M.smegmatis_MC2_155      INSPQQLWEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSKWGAFL
MAB_3148c|M.abscessus_ATCC_199      IESPEQFWQALLRGEDFITEVPPARWDLTEYYDPESGVPGKSPSKWGAFL
Mb2959|M.bovis_AF2122/97            VTGPESFWQLLADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFV
Rv2934|M.tuberculosis_H37Rv         VTGPESFWQLLADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFV
MLBr_02354|M.leprae_Br4923          VTGPDSFWQLLVDGGDAISEVPPDRWDADAFYDPDPSASGRMTTKWGGFV
MMAR_1773|M.marinum_M               VSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWGGFI
MUL_2016|M.ulcerans_Agy99           VSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWGGFI
Mflv_3391|M.gilvum_PYR-GCK          ATDPDSYWKVLESGTNAVTEVPADRWDGDAYYDPDPMAPGRMPSKWGAYI
Mvan_3124|M.vanbaalenii_PYR-1       VTGPDSYWELLENGTDAITEVPADRWDGDAFYDPDPMAPGRMPTKWGAYL
                                      .*:  *: *  * : : ::*  ***   ::**:. ..*:  ::**.::

MAV_2370|M.avium_104                DDVAGFDPEFFGINEREATAMDPQHRLLLETSWEAMEHAGLTEERVADSR
TH_4621|M.thermoresistible__bu      DDVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSS
MSMEG_4727|M.smegmatis_MC2_155      DDPAAFDPEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSA
MAB_3148c|M.abscessus_ATCC_199      EDVGGFDADFFSINEREAVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQ
Mb2959|M.bovis_AF2122/97            SDVDAFDADFFGITPREAVAMDPQHRILLEVAWEALEHAGIPPDSLSGTR
Rv2934|M.tuberculosis_H37Rv         SDVDAFDADFFGITPREAVAMDPQHRMLLEVAWEALEHAGIPPDSLSGTR
MLBr_02354|M.leprae_Br4923          PDVDAFDAEFFGITPREAVAMDPQHRMLLEVAWESLEHAGIAPDSLSGTR
MMAR_1773|M.marinum_M               DDVAGFDADFFGITPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTR
MUL_2016|M.ulcerans_Agy99           DDVAGFDADFFGITPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTR
Mflv_3391|M.gilvum_PYR-GCK          DDMAGFDAEFFGITPREAAAMDPQQRIVLEVAYEALENAGLAPDTVGDIR
Mvan_3124|M.vanbaalenii_PYR-1       DDVSGFDADFFGITPREAAAMDPQQRVLLEVAWEALENAGLAPDTLSETR
                                     *  .**.:**.*. *** ::***:*::**.:::::*::*:    :    

MAV_2370|M.avium_104                TGVFIGLTHGDYQLLAADTRSVEGAYGFSGSNFSLASGRIAYALGVHGPA
TH_4621|M.thermoresistible__bu      TGVFVGLSHDDYALLTSDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPA
MSMEG_4727|M.smegmatis_MC2_155      TGVFMGLTHNDYAHLAADAKALEGPYGFTGTSFSLASGRIAYALGVHGPA
MAB_3148c|M.abscessus_ATCC_199      TGVFVGVTHNDYQLVAADAADLGGPYGFAGTNFCMASGRISYALGVHGPS
Mb2959|M.bovis_AF2122/97            TGVMMGLSSWDYTIVNIERRADIDAYLSTGTPHCAAVGRIAYLLGLRGPA
Rv2934|M.tuberculosis_H37Rv         TGVMMGLSSWDYTIVNIERRADIDAYLSTGTPHCAAVGRIAYLLGLRGPA
MLBr_02354|M.leprae_Br4923          TAVMMGLSSWDYTIVNIERRADIDAYLSTGTPHCAAVGRISYLLGLRGPA
MMAR_1773|M.marinum_M               TAAVMGLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPA
MUL_2016|M.ulcerans_Agy99           TAAVMGLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPA
Mflv_3391|M.gilvum_PYR-GCK          GAVMLGVYYNEYQSASAGNPDTIDAYSATGNAHSVTVGRIAYLLGLKGPA
Mvan_3124|M.vanbaalenii_PYR-1       TAVMMGVYYTEYQNSSAGNPDTIDAYSATGNAHSVTVGRIAYLLGLKGPA
                                     ...:*:   :*            .*  :*. .. : ***:* **::**:

MAV_2370|M.avium_104                LTVDTACSSGLTAIHLACRSLHEGESDLALAGGATLALDPRKFSAGSAEG
TH_4621|M.thermoresistible__bu      VTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLG
MSMEG_4727|M.smegmatis_MC2_155      ITVDTACSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAG
MAB_3148c|M.abscessus_ATCC_199      LTVDAGCAAGLATVHMGCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQR
Mb2959|M.bovis_AF2122/97            VAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSPFTAIALSKWS
Rv2934|M.tuberculosis_H37Rv         VAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSPFTAIALSKWS
MLBr_02354|M.leprae_Br4923          MAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSPFTAIALSKWS
MMAR_1773|M.marinum_M               VAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWS
MUL_2016|M.ulcerans_Agy99           VAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWS
Mflv_3391|M.gilvum_PYR-GCK          VAVDTACSSSLVSIHLACQSLRMRESDLALAGGVSLSLRPETQLALGKWG
Mvan_3124|M.vanbaalenii_PYR-1       VAVDTACSSSLVSIHLACHSLRMRESDLALAGGVSLNLRPETQLALAKWG
                                    ::**:.*::.* ::*:.*:**   *:*:.****. : * *    . .   

MAV_2370|M.avium_104                MLSPTGRCHAFDVAADGFVGGEGSVMLLLKRLNDALRDGDRILAVVRGTA
TH_4621|M.thermoresistible__bu      MLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTA
MSMEG_4727|M.smegmatis_MC2_155      MLSPTGHCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDRILAVIRGTA
MAB_3148c|M.abscessus_ATCC_199      MLSPTGRCHTFTGEADGFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTA
Mb2959|M.bovis_AF2122/97            ALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA
Rv2934|M.tuberculosis_H37Rv         ALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA
MLBr_02354|M.leprae_Br4923          ALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSA
MMAR_1773|M.marinum_M               ALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA
MUL_2016|M.ulcerans_Agy99           ALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA
Mflv_3391|M.gilvum_PYR-GCK          MLSPHGKCYAFDSRADGFVRGEGAGVVVLKRLTDAVRDGDRVLGVVRGSA
Mvan_3124|M.vanbaalenii_PYR-1       MLSPHGKCFAFDSRADGFVRGEGAGVVVLKRLTDAVRDGDRVLGVVRGSA
                                     *** *:* :*   ***** .**. :: **** **: * **:*.*:**:*

MAV_2370|M.avium_104                ANQDGHTVNIATPSKTAQTAVYRAALAAAGVDAGTVGMVEAHGPGTPVGD
TH_4621|M.thermoresistible__bu      ANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGD
MSMEG_4727|M.smegmatis_MC2_155      TNQDGRTVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEAHGTGTPVGD
MAB_3148c|M.abscessus_ATCC_199      SNQDGRTVNQSTPSSEAQAAACRTALAVAGVEADTVGLIEAHGTGTPVGD
Mb2959|M.bovis_AF2122/97            TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGD
Rv2934|M.tuberculosis_H37Rv         TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGD
MLBr_02354|M.leprae_Br4923          TNQDGRSNGMTAPNALAQRDVITTALRLADITPDSVNYVETHGTGTVLGD
MMAR_1773|M.marinum_M               INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGD
MUL_2016|M.ulcerans_Agy99           INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGD
Mflv_3391|M.gilvum_PYR-GCK          VNQDGRSNGLTAPNAPSQRDVITRALRSADVAAGTVNFVETHGTGTSLGD
Mvan_3124|M.vanbaalenii_PYR-1       VNQDGRSNGLTAPNAPSQRDVITRALRSADVAAGTVDYIETHGTGTGLGD
                                     *.**:: . ::*.  :*  .   **  *.  . :*. :*:**.** :**

MAV_2370|M.avium_104                PIEYASLAEVYG-----IDGPCALASVKTNFGHAQAASGALGMMKAILAL
TH_4621|M.thermoresistible__bu      PIEYNSLTQVYG-----KTGPCALTSVKTNFGHAESAAGALGMMKAILAL
MSMEG_4727|M.smegmatis_MC2_155      PLEFSSLAEVYG-----TDGPCALGSIKTNFGHTQSAAGALGVMKAVLAL
MAB_3148c|M.abscessus_ATCC_199      PIEYTGLAQVYG-----VDGPCAVGSVKTNFGHTMSAAGALGLMKIVLAV
Mb2959|M.bovis_AF2122/97            PIEFESLAATYGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAV
Rv2934|M.tuberculosis_H37Rv         PIEFESLAATYGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAV
MLBr_02354|M.leprae_Br4923          PIEFESLAATY----GRGESSCALGSVKTNIGHLEAAAGVAGFIKTVLAL
MMAR_1773|M.marinum_M               PIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAV
MUL_2016|M.ulcerans_Agy99           PIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAV
Mflv_3391|M.gilvum_PYR-GCK          PIEFDALSAVYG----KGDTPCALGAVKTNMGHMEAAAGIGGFIKAVLTL
Mvan_3124|M.vanbaalenii_PYR-1       PIEFDALAAVYG----KGEVPCALGAVKTNMGHLEAAAGVAGFIKTVLSL
                                    *:*: .*: .*         .**: ::***:**  :*:*  ..:*  *::

MAV_2370|M.avium_104                QHGVVPRNLHFTQLPDDLARIDTKLFVPQQTTPWVSNGGHPRRAAVSSYG
TH_4621|M.thermoresistible__bu      QHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREGCPRRAAVSSYG
MSMEG_4727|M.smegmatis_MC2_155      QHNVIPQNLHFTRLPDQMAEIETGLFVPETITPWPVREGQPRRAAVSAYG
MAB_3148c|M.abscessus_ATCC_199      EHGVVPPNLHFTGIPDKLAPVKTNLFVPQTVIPWPGKAQGPRRAGVSAYG
Mb2959|M.bovis_AF2122/97            QRGHIPRNLHFTRWNPAIDASATRLFVPTESAPWPAAAG-PRRAAVSSFG
Rv2934|M.tuberculosis_H37Rv         QRGHIPRNLHFTRWNPAIDASATRLFVPTESAPWPAAAG-PRRAAVSSFG
MLBr_02354|M.leprae_Br4923          QHAYIPRNVHFTQWNPAIDASTTRLFVPTESAPWPAIPG-PRRGAVSSFG
MMAR_1773|M.marinum_M               AHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG---LRRAAVSSFG
MUL_2016|M.ulcerans_Agy99           AHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG---LRRAAVSSFG
Mflv_3391|M.gilvum_PYR-GCK          QHGAIAPNLHFQKWNPSINATGTRLFVPTEKTDWPETDH-PRRAAVSSFG
Mvan_3124|M.vanbaalenii_PYR-1       QHGKIAPNLNFEKWNPQIDPKPTRLFVPTEAQDWPKSEH-PRRAAVSSFG
                                     :  :. *::*      :    * ****     *       **..**::*

MAV_2370|M.avium_104                LSGTNVHAILEQAP-EPAPETVAPEGISAESPLLFPLSSTSADELRRTAG
TH_4621|M.thermoresistible__bu      MSGTNVHAVLEQAP-EPVQRPEESADTDAAGPLVFALSSTSAEELRRTAG
MSMEG_4727|M.smegmatis_MC2_155      LSGTNVHAVLEQAPESPAETAAEAISPKAGNALVFPVSASSADALRSTAQ
MAB_3148c|M.abscessus_ATCC_199      MSGSNVHAVVEQAP-PVESSTPPAVESPLGSQLIFPVSSTSAEELRRTAA
Mb2959|M.bovis_AF2122/97            LSGTNAHVVVEQAP---DTAV--AAAGGMPYVSALNVSGKTAARVASAAA
Rv2934|M.tuberculosis_H37Rv         LSGTNAHVVVEQAP---DTAV--AAAGGMPYVSALNVSGKTAARVASAAA
MLBr_02354|M.leprae_Br4923          LSGTNAHVVIEQAP---DTTVPISAAVGRQYVSALVVSGKTVTRVASAAA
MMAR_1773|M.marinum_M               LSGTNAHVVLEQPP---APAP---ADQPRSGLSALVVSGKTPQRVAAMAS
MUL_2016|M.ulcerans_Agy99           LSGTNAHVVLEQPP---APAP---ADQPRSGLSALVVSGKTPQRVAAMAS
Mflv_3391|M.gilvum_PYR-GCK          MGGTNAHIVLEQGP---DVAA--APVDPAPKVATLVVSGKTPQRLAAAAA
Mvan_3124|M.vanbaalenii_PYR-1       MGGTNAHIVLEQGP---EPAP--AGAADTG-VVTLVVSGKTSERLAASAR
                                    :.*:*.* ::** *                    : :*..:   :   * 

MAV_2370|M.avium_104                RLADWVHAHGD------LALP-DLAYTLARRRVHRPVRTAVLAGDRAQLI
TH_4621|M.thermoresistible__bu      RLAEWVEAHTD------EVVPADLAYTLARRRAHRPVRTTVIADGVEALT
MSMEG_4727|M.smegmatis_MC2_155      HLADWLLRSGDGNGRGPAIDLGDLAYTLARRRGFRAARSAVLAGDRGTLV
MAB_3148c|M.abscessus_ATCC_199      RLADWVAERPE-------VAPGDVGYTLARRRAHRSVRTAVVADGADELI
Mb2959|M.bovis_AF2122/97            VLADWMSGPGA------AAPLADVAHTLNRHRARHAKFATVIARDRAEAI
Rv2934|M.tuberculosis_H37Rv         VLADWMSGPGA------AAPLADVAHTLNRHRARHAKFATVIARDRAEAI
MLBr_02354|M.leprae_Br4923          VLADWMSGPGA------AAPLADVAYTLNQHRVRHPKLATVIARDHADAV
MMAR_1773|M.marinum_M               ALADWVDGPGG------QTPLADVAHTLNHHRARHGKFGAVVARDRAGAV
MUL_2016|M.ulcerans_Agy99           ALADWVDGPGA------QTPLADVAHTLNHHRARHGKFGAVVARDRAGAV
Mflv_3391|M.gilvum_PYR-GCK          SLADWLDGDGA------QVPLTDVAHTVNHHRSRFPTIATVCARTHAEAV
Mvan_3124|M.vanbaalenii_PYR-1       SLADWLDGDGA------DVPLVDVAYTVNHHRSRYQTIATVCARTHAEAV
                                     **:*:                *:.:*: ::*       :* *       

MAV_2370|M.avium_104                EALREVADGDTPYPAAVGRGDRG-------PVWVFSGQGSQWAAMGADLL
TH_4621|M.thermoresistible__bu      AGLREVADGDAPYQPAVGMDDKA-------PVWVFSGQGSQWAGMGAELL
MSMEG_4727|M.smegmatis_MC2_155      EGLRQIADGEAMPQQAVTNDDRG-------PVWVFSGQGSQWASMGAELL
MAB_3148c|M.abscessus_ATCC_199      DALRGVAEGDAPYPAAVAQDDRG-------PVWLFSGQGSQWAGMGAELL
Mb2959|M.bovis_AF2122/97            AGLRALAAGQPRVGVVDCDQHAG----GPGRVFVYSGQGSQWASMGQQLL
Rv2934|M.tuberculosis_H37Rv         AGLRALAAGQPRVGVVDCDQHAG----GPGRVFVYSGQGSQWASMGQQLL
MLBr_02354|M.leprae_Br4923          AGLRALAAGQPRVGVVGCDQHAA----GPGRVFVYSGQGSQWAGMGRQLL
MMAR_1773|M.marinum_M               EGLRALAAGQPGPGVLGCQDVQN----QPGTVFVYSGQGSQWVGMGRQLL
MUL_2016|M.ulcerans_Agy99           EGLRALAAGQPGPGVLGCQDVQN----QPGTVFVYSGQGSQWVGMGRQLL
Mflv_3391|M.gilvum_PYR-GCK          AGLRALAAGQTAPGVVGARAAKS----GTGTVFLYSGQGAQWAGMGRTLL
Mvan_3124|M.vanbaalenii_PYR-1       TGLRALADGRPAPGVIAPHDAKGGVAAGKGVVFLYSGQGAQWAGMGKTLL
                                     .** :* * .                    *:::****:**..**  **

MAV_2370|M.avium_104                ATEPVFAATVAQAEPLIARESGFSVAEAMSAPQTVTGQDRVQPTLFTMQV
TH_4621|M.thermoresistible__bu      ATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTGIDRVQPTLFAIQV
MSMEG_4727|M.smegmatis_MC2_155      DREPAFAAAIAELEPLIAAESDFSVTEALTASETVTGIDRVQPTIFAVQV
MAB_3148c|M.abscessus_ATCC_199      GKEPVFAETIARLEPLIHAESGFSVTDAISAPETVTGIDRVQPTLFAMQV
Mb2959|M.bovis_AF2122/97            ANEPAFAKAVAELDPIFVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQL
Rv2934|M.tuberculosis_H37Rv         ANEPAFAKAVAELDPIFVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQL
MLBr_02354|M.leprae_Br4923          VDEPAFAKAVAELEPTFVAQVGFSLEHTLAYGDEVVGIERIQPVLVGIQL
MMAR_1773|M.marinum_M               ADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQL
MUL_2016|M.ulcerans_Agy99           ADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQL
Mflv_3391|M.gilvum_PYR-GCK          ADEPAFAAAVDELEPAFVDKVGFSLRQTLEAGEPVTGIDRIQPVLVGMQL
Mvan_3124|M.vanbaalenii_PYR-1       TSEPAFAAAVDELEPAFVEKVGFSLRQTLEAGEPVVGIDRIQPVLVGMQL
                                      *  **  : . :* .  : .**: .::     *.* :*:**.:. :*:

MAV_2370|M.avium_104                ALAATMKAHGVRPGAVIGHSLGEAAAAVVAGALSLEDGARVICRRSRLMS
TH_4621|M.thermoresistible__bu      ALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICRRSRLCL
MSMEG_4727|M.smegmatis_MC2_155      ALAAAMRSHGVVPGAVIGHSMGEVAASVVSGALSLEDGVKVICRRTRLMT
MAB_3148c|M.abscessus_ATCC_199      SLAATLASYGVRPGAVIGHSMGEVAAAVVSEALSLEDGVKVICRRSQLML
Mb2959|M.bovis_AF2122/97            ALTELWRSYGVIPDAVIGHSMGEVSAAVVAGALTPEQGLRVITTRSRLMA
Rv2934|M.tuberculosis_H37Rv         ALTELWRSYGVIPDAVIGHSMGEVSAAVVAGALTPEQGLRVITTRSRLMA
MLBr_02354|M.leprae_Br4923          ALTELWRSYGVTPDAVIGHSMGEVSAAVVAGALTPEQGLRVIATRSRLMA
MMAR_1773|M.marinum_M               ALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMA
MUL_2016|M.ulcerans_Agy99           ALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMA
Mflv_3391|M.gilvum_PYR-GCK          ALTQLWRSYGVEPDAVIGHSMGEATAAVVAGVLTPAEGFDIIATRTRLMK
Mvan_3124|M.vanbaalenii_PYR-1       ALTALWRSYGVEPDAVIGHSMGEATAAVVAGVLTPAEGFDVIATRTRLMK
                                    :*:    ::** *.**:***:**.:*:**: .*:  :*  :*  *::*  

MAV_2370|M.avium_104                RVAGTGATASVELPAQQVLSELTARGISDVVVAVVASPQSTVIAGAAPTV
TH_4621|M.thermoresistible__bu      RLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIGGATDTV
MSMEG_4727|M.smegmatis_MC2_155      RIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVVASPQSTVVGGATASV
MAB_3148c|M.abscessus_ATCC_199      RISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQSTVVGGATETV
Mb2959|M.bovis_AF2122/97            RLSGQGAMALLELDADAAEALIAGY--PQVTLAVHASPRQTVIAGPPEQV
Rv2934|M.tuberculosis_H37Rv         RLSGQGAMALLELDADAAEALIAGY--PQVTLAVHASPRQTVIAGPPEQV
MLBr_02354|M.leprae_Br4923          RLSGQGAMALLELDADAAEALIADY--PEVTLAVYASPRQSVIAGLPESV
MMAR_1773|M.marinum_M               RLAGQGAMALLELDSDAAEALIADY--PQVTLAVHASPHQSVVAGPPESV
MUL_2016|M.ulcerans_Agy99           RLAGQGAMALLELDSDAAEALIADY--PQVTLAVHASPHQSVVAGPPESV
Mflv_3391|M.gilvum_PYR-GCK          RLSGQGAMALLELDAQATEKLIADR--PDITIAVYASPKQCVIAGPPEQV
Mvan_3124|M.vanbaalenii_PYR-1       RLSGQGAMALLELDAQATEKLIADR--SDVTIAVYASPKQTVIAGPPEQV
                                    *::* ** * ::* :: .   ::     ::.::* ***.. *:.* .  *

MAV_2370|M.avium_104                RDLVTAWQERGVMAREVPTDVAFHSPQVDPIMDDLTDALAEISPRPPEVP
TH_4621|M.thermoresistible__bu      RELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQPMTPTVP
MSMEG_4727|M.smegmatis_MC2_155      RELIEMWESRGVMAREIAVDVASHSPQVDPILDDLIEALADLDPAEPEIP
MAB_3148c|M.abscessus_ATCC_199      RQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADALEDLTPRTPVVP
Mb2959|M.bovis_AF2122/97            DTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPSIP
Rv2934|M.tuberculosis_H37Rv         DTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPSIP
MLBr_02354|M.leprae_Br4923          DAVISVVAEQNRLARRVDVEVASHHSIIDPILPELRNALADLVPQTPIIP
MMAR_1773|M.marinum_M               DAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIP
MUL_2016|M.ulcerans_Agy99           DAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIP
Mflv_3391|M.gilvum_PYR-GCK          DELVALVDAQGKLARRVEVDVASHHPTIDPVLGELRDALSYLSPAAPKIP
Mvan_3124|M.vanbaalenii_PYR-1       DELVAAVDAQGKLARRIEVDVASHHPTIDPVLPELREALAYLTPAAPKIP
                                      ::     :. :**.: .:** * . :**:: :* . *  : *  * :*

MAV_2370|M.avium_104                YYSATLFDPREQPVCDARYWANNMRRMVRFATAVQAAL------EDGYRV
TH_4621|M.thermoresistible__bu      YYSATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAAL------EDGFRV
MSMEG_4727|M.smegmatis_MC2_155      YYSATLYDPRDYADYDAYYWADNLRHTVRFSAAVQAAL------EDGHRV
MAB_3148c|M.abscessus_ATCC_199      LYSSVSFDPRERPIMDADYWVDNLRHTVRFAAAVQAAL------DDGYRV
Mb2959|M.bovis_AF2122/97            IISTT-YESAQ-PVADADYWSANLRNPVRFHQAVTAAG-------VDHNT
Rv2934|M.tuberculosis_H37Rv         IISTT-YESAQ-PVADADYWSANLRNPVRFHQAVTAAG-------VDHNT
MLBr_02354|M.leprae_Br4923          IITTT-HEHTQ-AVMDADYWAANLRNPVRFHQAIAQAVSGVGGFNRTCHS
MMAR_1773|M.marinum_M               MITTT-CEQPQ-PVLDADYWAANLRNPVRFHQAITTAG-------AQHHT
MUL_2016|M.ulcerans_Agy99           MITTT-CEQPQ-PVLDADYWAANLRNPVRFHQAITTAG-------AQHHT
Mflv_3391|M.gilvum_PYR-GCK          LVSTVAYAGSA-PLYSADYWAANLRNPVRFSQAVHEAA-------ADHSN
Mvan_3124|M.vanbaalenii_PYR-1       LVSTVGYAGDA-PMYSADYWAANLRNPVRFSQAVHDAS-------AENSN
                                      ::.       .  .* **  *:*. ***  *:  *             

MAV_2370|M.avium_104                FAELAPHPLLVRALEQTARSREIPMAALAGMRRGQALPHGLRGFVADLHN
TH_4621|M.thermoresistible__bu      FGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTMVGDLFA
MSMEG_4727|M.smegmatis_MC2_155      FAELSPHPLLTHPVEQTARSLDMPLAVFAAMRRQQEMPHGLLGFVADLHS
MAB_3148c|M.abscessus_ATCC_199      FGELAPHPLLVYPAEQTARSLDIPMVALAGMRREQELPHGLRDFVGDLYT
Mb2959|M.bovis_AF2122/97            FIEISPHPVLTHALTDTLDPD-GSHT--VMSTMNRELDQ-TLYFHAQLAA
Rv2934|M.tuberculosis_H37Rv         FIEISPHPVLTHALTDTLDPD-GSHT--VMSTMNRELDQ-TLYFHAQLAA
MLBr_02354|M.leprae_Br4923          FIEISPHPVLTHAITDTVGGS-GGHV--VTSAMNRDLDQ-TLFFHAQLAT
MMAR_1773|M.marinum_M               FVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRDGDD-AITFHTNLAA
MUL_2016|M.ulcerans_Agy99           FVEISPHPLLTHAITDTLAAA-DSRTRLITATLQRDGDD-AITFHTNLAA
Mflv_3391|M.gilvum_PYR-GCK          FVEISPHPLLTHAISDTLAAQSTSRKFHVGATLNRDHPE-PLAFHAQLSA
Mvan_3124|M.vanbaalenii_PYR-1       FIEISPHPLLTHAISDTLAAQSTSRRYHVGATVNRDNPE-PLAFHAQLAA
                                    * *::***:*. .  :*                 :   .    :  :*  

MAV_2370|M.avium_104                AGAAVDFSVLYPTGRLVDAPLPTWTHRRLWLTDGGLESPTHGGCTVAVHP
TH_4621|M.thermoresistible__bu      AGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGEQQTRGGCTITVHP
MSMEG_4727|M.smegmatis_MC2_155      AGAAVDFSVLYPTGRLLDAPLPAWTHSTLLLDR-ELESSAPGVPSVSVHP
MAB_3148c|M.abscessus_ATCC_199      AGGAVDFSVLYPTGQLVDVPLPSWTRRSYLLDLSAQAQQGHGTHTVAVHP
Mb2959|M.bovis_AF2122/97            VG---VAASEHTTGRLVDLPPTPWHHQRFWVTDRSAMSE-----LAATHP
Rv2934|M.tuberculosis_H37Rv         VG---VAASEHTTGRLVDLPPTPWHHQRFWVTDRSAMSE-----LAATHP
MLBr_02354|M.leprae_Br4923          VG---VTESDSAKGRLVDLPPTPWQHSRFWVADRSAMSE-----LAVAHP
MMAR_1773|M.marinum_M               VG---KKPADAVTGQLADIPVTPWQHTQFWVEDRSGISE-----LVAAHP
MUL_2016|M.ulcerans_Agy99           VG---KKPADAVTGQLADIPVTPWQHTQFWVEDRSGISE-----LVAAHP
Mflv_3391|M.gilvum_PYR-GCK          LRPPAVTAPDGATGRVVDVPATAWQHTPYWMADRSGGPQ-----FAGAHP
Mvan_3124|M.vanbaalenii_PYR-1       VRPPAVQAPEGTPGRLADIPPTAWQHSPYWMVDRSAGQG-----FSGAHP
                                                 *:: * * ..* :    :                .**

MAV_2370|M.avium_104                LLGPHVHLQEEPERHLWQADVGTAAQPWLADHQIRNVVVLPGAAYCEMAL
TH_4621|M.thermoresistible__bu      LLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAYCEMAL
MSMEG_4727|M.smegmatis_MC2_155      LLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAYCEMAL
MAB_3148c|M.abscessus_ATCC_199      LLGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRHVAVYPGAAYCEMAL
Mb2959|M.bovis_AF2122/97            LLGAHIEMPRNGD-HVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEIAL
Rv2934|M.tuberculosis_H37Rv         LLGAHIEMPRNGD-HVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEIAL
MLBr_02354|M.leprae_Br4923          LLGVHVEMPGSGD-HGWQADVGTDVCPWLADHKVFGQPIMPAAAFAEIAV
MMAR_1773|M.marinum_M               LLGVHIEVPSGHD-HVWQADVGTKACPWLGDHKVFGQAIMPAAGFAEIAL
MUL_2016|M.ulcerans_Agy99           LLGVHIEVPSGHD-HVWQADVGTKACPWLGDHKVFGQAIMPAAGFAEIAL
Mflv_3391|M.gilvum_PYR-GCK          LLGLHVELPAGAG-HVWQSDVGLEAHPWLADHIVHGLPVMPGAGFAEIAL
Mvan_3124|M.vanbaalenii_PYR-1       LLGLHVELPSGTG-HVWQSDVGVQAHPWLADHIVHGLAVMPGAGFAEIAL
                                    *** *: :      * ** *:*    **:.** :      *.*.:.*:*:

MAV_2370|M.avium_104                AAARSVLGAT-AEVRD------IRFEQALLLDEQTTVDASASVSSPGVLH
TH_4621|M.thermoresistible__bu      AAAREVIDSDGVEVRD------VRFEQMLLLDEQTEVSAVASAVEPGTLE
MSMEG_4727|M.smegmatis_MC2_155      AAVTPVLGDT-GEVHD------LKFHDMLLLDDATPVWVSAAVTAPGTAE
MAB_3148c|M.abscessus_ATCC_199      SAAAAVFGEG-SAVQS------ISFEQLLTLGESTPISATATAKSADILE
Mb2959|M.bovis_AF2122/97            AAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIR
Rv2934|M.tuberculosis_H37Rv         AAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIR
MLBr_02354|M.leprae_Br4923          AAASEALGVPAGTSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKIR
MMAR_1773|M.marinum_M               AAASEAFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTR
MUL_2016|M.ulcerans_Agy99           AAASEAFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTR
Mflv_3391|M.gilvum_PYR-GCK          AAAQEALGLPATGVE-----VALEVQEMLLLDAHTTLTTQVSTAEDGTLR
Mvan_3124|M.vanbaalenii_PYR-1       AAGREALGLPATGVE-----VQLEVEQMLPLDDHTKLTTQLTRDDEENLR
                                    :*   .:.              . ..: * *.  * : .          .

MAV_2370|M.avium_104                FTVQS-HQGGEQARHASAVLGAATD-EQPAAHDLSALLTAHPHDDDGDEV
TH_4621|M.thermoresistible__bu      FAVET-AKDGEHERRATAVLGAADDTEPPQAHDIDALLAEHPTRIEGDEL
MSMEG_4727|M.smegmatis_MC2_155      FGVET-HQSGDRTQRATAVLRGDVDAERPAAHSIDALLAAHPNRVDGDEL
MAB_3148c|M.abscessus_ATCC_199      FVVET-HDEGDVVKRATAVLGNGGDVDMPIAYDLSALRAEHPHRESGDDL
Mb2959|M.bovis_AF2122/97            VEIYSRTRGGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVS--PADF
Rv2934|M.tuberculosis_H37Rv         VEIYSRTRGGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVS--PADF
MLBr_02354|M.leprae_Br4923          VEIYSRSPRGDFSRHATANVEHVSHNAVQPFQQAPGSSNGVTVS--PADF
MMAR_1773|M.marinum_M               IEIYSRSASG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIK--PADL
MUL_2016|M.ulcerans_Agy99           IEIYSRSASG-WRRHAVAKAETSTPSAAPVLEERTSRQDETDIK--PADL
Mflv_3391|M.gilvum_PYR-GCK          VEIHSRSEAGTWTRHAAGSVRAAAG---ATPPRPAPLSEGTPVS--PADF
Mvan_3124|M.vanbaalenii_PYR-1       VEIHSRSDAGSWTRHAVGTVKAAAG---PAPAKVVPASDGTPVS--PSDF
                                    . : :    *   ::* .                              :.

MAV_2370|M.avium_104                RRRMDRRGVQYGPAFAGLGAVHSGDETGT-VLAEVALPRQIRSQQAAYGA
TH_4621|M.thermoresistible__bu      RQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQIRSQQAPYGI
MSMEG_4727|M.smegmatis_MC2_155      RAGFGTVGIGHGAAFAGLSEAYVATAAEPTVVAAVALPGPLRSGQRGYTV
MAB_3148c|M.abscessus_ATCC_199      RASFDERGVQYGPAFQGLAAAYRGDETVRSVLAEVTLPRDVRAQQGSYIV
Mb2959|M.bovis_AF2122/97            YALLRQTGQHHGPAFAALSRIVRL--ADGSAETEISIPDEAPRHPG-YRL
Rv2934|M.tuberculosis_H37Rv         YALLRQTGQHHGPAFAALSRIVRL--ADGSAETEISIPDEAPRHPG-YRL
MLBr_02354|M.leprae_Br4923          YAVLRQTGQHHGPVFAVLTRITRL--LDGSAETEITLPDEVPRHPG-YRL
MMAR_1773|M.marinum_M               YALLRQAGQNHGPAFAALTRILRR--PDGSVETEITLSDEAPRHQG-YRI
MUL_2016|M.ulcerans_Agy99           YALLRQAGQNHGPAFAALTRILRR--PDGSVETEITLSDEAPRHQG-YRI
Mflv_3391|M.gilvum_PYR-GCK          YTALRRTGAHHAHAFAALTRIVR---AAGTADTEIVLPDEATPHRG-VAL
Mvan_3124|M.vanbaalenii_PYR-1       YTALRRTGAHHAHAFAALTRIVR---AGGRADTEIVLPDEATPHRG-IAL
                                       :   *  .. .*  *            . : : :.            

MAV_2370|M.avium_104                HPALLDACFQSVEAHP--AVRALGDGALGLVLGIRRLRAYGAARNAHYCY
TH_4621|M.thermoresistible__bu      HPALLDACFQSVAAHP--DVQGAGSGLL-LPLGVRRLQAFGPTRGARYCY
MSMEG_4727|M.smegmatis_MC2_155      HPALLDACFQSVIAHP--EVQNIASGML-LPLGVRRLRAYGSTRNVRYCL
MAB_3148c|M.abscessus_ATCC_199      HPALLDACFQSVIALP--DVQEASKDALPLPKGVRSLHAYESARATQYCY
Mb2959|M.bovis_AF2122/97            HPVVLDAALQSVGAAIPDGEIAGSAEASYLPVSFETIRVYRDIGRHVRCR
Rv2934|M.tuberculosis_H37Rv         HPVVLDAALQSVGAAIPDGEIAGSAEASYLPVSFETIRVYRDIGRHVRCR
MLBr_02354|M.leprae_Br4923          HPVVLDAALQSVGAAIPDGEVAESAEVSYLPVSFEAIRVYRDIGRHALCR
MMAR_1773|M.marinum_M               HPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYSNPGRHARCR
MUL_2016|M.ulcerans_Agy99           HPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYSNPGRHARCR
Mflv_3391|M.gilvum_PYR-GCK          HPVMLDAALQGLAAALGDDSLTDSNDVTYLPVGFGSVRVFAEVGRRAKCR
Mvan_3124|M.vanbaalenii_PYR-1       HPVMLDAALQGLAAAMSDETLSDSTDVTYLPVGFGSIRVFGDIGRRAKCR
                                    **.:***.:*.: *         .     *  ..  ::.:        * 

MAV_2370|M.avium_104                TRVTKADTSG-------VEADIDVLDEHGAVLLAVQGLRVGTSASESGTR
TH_4621|M.thermoresistible__bu      ARVTDADGSK-------AEADLDVLDEHGNVLLRVQGLLMGGAAADGDDR
MSMEG_4727|M.smegmatis_MC2_155      SRIVKADSFG-------VEADLELLDADGTVLLSAMGLQLGTGNSDKAEE
MAB_3148c|M.abscessus_ATCC_199      TRVTKVVGNE-------VEADIDLLDETGSVLIAVRGFRFGTGSSDDEQR
Mb2959|M.bovis_AF2122/97            AHLTNL-DGGTG-----KMGRIVLINDAGHIAAEVDGIYLRR--VERRAV
Rv2934|M.tuberculosis_H37Rv         AHLTNL-DGGTG-----KMGRIVLINDAGHIAAEVDGIYLRR--VERRAV
MLBr_02354|M.leprae_Br4923          ARLTNL-DGGTG-----KLGKIVLIDDAGYVAAEVDGIYLRR--IERRVV
MMAR_1773|M.marinum_M               AQLTNLNDGGAG-----KLGRITLTDDAGNVTVEINDIYLRR--VERRSV
MUL_2016|M.ulcerans_Agy99           AQLTNLNDGGAG-----KLGRITLTDDAGNVTVEITDIYLRR--VERRSV
Mflv_3391|M.gilvum_PYR-GCK          AELLSVASGVDGQGSGDAVGRVTLTDDTGTVLAQVDDVALKR--IQRRTV
Mvan_3124|M.vanbaalenii_PYR-1       AELVSVVE-----DSGDAMGRVTLTDDTGTVLAQVDDVHLKR--VQRRTV
                                    :.: .              . : : :  * :     .. .     :    

MAV_2370|M.avium_104                DRVLTERLLNIEWRQRELPEP------EHADAASWLLIGTT-------AT
TH_4621|M.thermoresistible__bu      DRVLGERLLTIEWQRRDLPEA------DSA-AGKWLLVSTS-------AT
MSMEG_4727|M.smegmatis_MC2_155      ERLLDERLLTIEWQQRELPRPEGS---ETVDAGSWLVILAGD------DD
MAB_3148c|M.abscessus_ATCC_199      DQLLNNRLLAIEWQQQRLPES------VSGAPRRWLLVSTG-------ES
Mb2959|M.bovis_AF2122/97            PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQ
Rv2934|M.tuberculosis_H37Rv         PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQ
MLBr_02354|M.leprae_Br4923          PLPLAQKIFDAEWIESPIPASRALEQITETARASWLVLTDWDP------S
MMAR_1773|M.marinum_M               PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLT----------D
MUL_2016|M.ulcerans_Agy99           PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLT----------D
Mflv_3391|M.gilvum_PYR-GCK          PLPLSQKIFDSRWVPAQATAG-------AAQAGSWLVLADG-------DH
Mvan_3124|M.vanbaalenii_PYR-1       PLPLSQKIFDSRWVESAAAAG-------TTATGSWLALADG-------AA
                                       * ::::  .*     .               ** :            

MAV_2370|M.avium_104                ADVLASTLADTLKNHGAQCTTMAWPQQADHTAHAEQLRNQWRGDGFTGVV
TH_4621|M.thermoresistible__bu      ADVSATRLSDALKQAGAESTSMCWPQQADHADNVDRFR-AGIADGVTGVV
MSMEG_4727|M.smegmatis_MC2_155      ENPRAAGVVSALIGAGMPTTTMAWSHDADHDAQAAALTARLDEQPLAGVA
MAB_3148c|M.abscessus_ATCC_199      VDPWAAELIDSLKVRESEVSLIQWRPNTDRVAALKLLYDQLESGTFDGVL
Mb2959|M.bovis_AF2122/97            AKSMADDFVQQWRSPMRRVHTADIHDESAVLAAFAETAGDPEH-PPVGVV
Rv2934|M.tuberculosis_H37Rv         AKSMADDFVQQWRSPMRRVHTADIHDESAVLAAFAETAGDPEH-PPVGVV
MLBr_02354|M.leprae_Br4923          IKSLTDEFIARWRSPMRRVYTANLHDESAMLAAFAETAGDPEH-PPIGVV
MMAR_1773|M.marinum_M               AKSNADEFVARWSSPQRRVITADLGDEAAMLAAFAETAGDPER-LPVGVV
MUL_2016|M.ulcerans_Agy99           AKSNADEFVARWSSPQRRVITADLGDEAAMLAAFAETAGDPER-LPVGVV
Mflv_3391|M.gilvum_PYR-GCK          TLASAERFAQSFGDAQHRVVTARLGDEAAVRDAFASATTDAAL-PPAGVV
Mvan_3124|M.vanbaalenii_PYR-1       GQAAAQDFASRFGADTRRVITADLGDESAVREAFATATADPDL-PPVGVV
                                        :  .                  ::                   ** 

MAV_2370|M.avium_104                VLTGP-KNGDNDQ-------ESALLSRDHVQHLVRIARELT-DLPGEPPR
TH_4621|M.thermoresistible__bu      VLTGP-KNGNPDD-------AAARRGSDYVRHLVRITRELA-EIDGDAPR
MSMEG_4727|M.smegmatis_MC2_155      VIVGD-SETGTDAHD---VGADARRGADHVRHLVRIARTLA-DAVGEPPR
MAB_3148c|M.abscessus_ATCC_199      VVTAPGSEGGADR--------VVLQGADQVRHLVRITRELV-DLPGEPPR
Mb2959|M.bovis_AF2122/97            VFVGGASSR---------LDDELAAARDTVWSITTVVRAVVGTWHGRSPR
Rv2934|M.tuberculosis_H37Rv         VFVGGASSR---------LDDELAAARDTVWSITTVVRAVVGTWHGRSPR
MLBr_02354|M.leprae_Br4923          IFVGGAATG---------LDDGLVQARDSVWSISTVVRAIVSTWHGRSPR
MMAR_1773|M.marinum_M               VFVGGAGNNSGAADDGRISYDGLIQSRDTVWQISTVVRAIVGTWHGRAPR
MUL_2016|M.ulcerans_Agy99           VFVGGAGNNSGTADDGRISYDGLIQSRDTVWQISTVVRAIVGTWHGRAPR
Mflv_3391|M.gilvum_PYR-GCK          VLVDVP------AFDGADAAGGLAAAQNAVWEIAETVRTIVGSWHGTPPR
Mvan_3124|M.vanbaalenii_PYR-1       VFCDFGGNP--ATLDGTDVAGGLEHARDVIWGVAGTVRAIVGSWHGKAPR
                                    :.                       . : :  :   .* :.    * .**

MAV_2370|M.avium_104                LYVVTRNAQTVLPN-DVPNLGQAGLRGLVRVIGMEHPQLGAGQIDVDEST
TH_4621|M.thermoresistible__bu      LFVVTRGAQAVLPQ-DRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDA
MSMEG_4727|M.smegmatis_MC2_155      LYVVTHRSQHVLDT-DEPYLEHSGLRGLIRVVGMEHPRLRATQIDVDDST
MAB_3148c|M.abscessus_ATCC_199      LFVVTRNAQTVVDG-DITNLEQAGLRGLVRVIGAEYPHLRVTHIDVDRHT
Mb2959|M.bovis_AF2122/97            LWLVTGGGLSVADD-EPGTPAAASLKGLVRVLAFEHPDMRTTLVDLDITQ
Rv2934|M.tuberculosis_H37Rv         LWLVTGGGLSVADD-EPGTPAAASLKGLVRVLAFEHPDMRTTLVDLDITQ
MLBr_02354|M.leprae_Br4923          LWLIAGGGLSVQDD-ELGAPATAALKGLVRVLALENPDLRATLLDLDATQ
MMAR_1773|M.marinum_M               LWLVTEGGLVVHD--EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGA
MUL_2016|M.ulcerans_Agy99           LWLVTEGGLVVHD--KPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGA
Mflv_3391|M.gilvum_PYR-GCK          LWVVSRGGLAVTDGDNGGNPGVGTLKALIRVLAYEHPDLRATLLDVGADG
Mvan_3124|M.vanbaalenii_PYR-1       LWLVTQGGLVVSPEDGQGNPGANSLKGLARVLAYEHPDLKTTLLDTGSDG
                                    *::::  .  *             *:.* **:. * * : .  :*     

MAV_2370|M.avium_104                DAQALARQLLAGSE-----EDETAWRDGAWYTARLCPAPLLPEERHTAVA
TH_4621|M.thermoresistible__bu      DLDRVAVQLLGGGA-----EDETAWRDGQWYTARLSLSPLRPEERKQAVV
MSMEG_4727|M.smegmatis_MC2_155      AHEALVRQLLSGSP-----EDETAWRDGQWYAARLCPSPLRAAERRTAVA
MAB_3148c|M.abscessus_ATCC_199      AAQNVAGELVSGSE-----EDETAWREDHWYRARLNLGPLGPDDWRSTVA
Mb2959|M.bovis_AF2122/97            DPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDVS-------
Rv2934|M.tuberculosis_H37Rv         DPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDVS-------
MLBr_02354|M.leprae_Br4923          DQIAALTAELHNSASEFGGDDVIAWRGQHRFVERLCKATLDAG-------
MMAR_1773|M.marinum_M               DSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEP------
MUL_2016|M.ulcerans_Agy99           DAVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEP------
Mflv_3391|M.gilvum_PYR-GCK          DTAAILATEIGSANDSTTTEDTIAWRDGSRLVERLSRAELPAV-------
Mvan_3124|M.vanbaalenii_PYR-1       ---AALATEIEAASASAVTEDVIAWRGGTRYVERLSRATLPAT-------
                                             :         :*  ***       :*  . :          

MAV_2370|M.avium_104                NHECDGMRLQIRTPGDLESLELVACDRIPPGPGQIEVAVSASSINFADVL
TH_4621|M.thermoresistible__bu      DCERDGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFADVL
MSMEG_4727|M.smegmatis_MC2_155      DNASEGMRLVVRNPGDLESMELVTFERGTPGPGQIEVAVKASSINFADVL
MAB_3148c|M.abscessus_ATCC_199      TPNNEGVRFEVRTPGDLQSLGFVAFDRVAPGPGQIEVSVTATSINFADVL
Mb2959|M.bovis_AF2122/97            --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02354|M.leprae_Br4923          --------------------------------------------------
MMAR_1773|M.marinum_M               --------------------------------------------------
MUL_2016|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3391|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

MAV_2370|M.avium_104                VAFGRYPAFEGRLPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGCWG
TH_4621|M.thermoresistible__bu      IAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWS
MSMEG_4727|M.smegmatis_MC2_155      VAFGRCPSFDGRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANGCWS
MAB_3148c|M.abscessus_ATCC_199      NVYGRYSSFEGRQ-ELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTGAWR
Mb2959|M.bovis_AF2122/97            --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02354|M.leprae_Br4923          --------------------------------------------------
MMAR_1773|M.marinum_M               --------------------------------------------------
MUL_2016|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3391|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

MAV_2370|M.avium_104                TFLTCDARLAVTLPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLI
TH_4621|M.thermoresistible__bu      TFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLI
MSMEG_4727|M.smegmatis_MC2_155      NFVTCEADLATKLPEGISEHEAAAVGLAYGTVWLGLTELARMSAGDKILI
MAB_3148c|M.abscessus_ATCC_199      SFVVVDANLAATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDKVLI
Mb2959|M.bovis_AF2122/97            --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02354|M.leprae_Br4923          --------------------------------------------------
MMAR_1773|M.marinum_M               --------------------------------------------------
MUL_2016|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3391|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

MAV_2370|M.avium_104                HSATGGVGQAAIAIARAAGAEIFATAGSEQRRQLLRDMGIEHVYDSRTVE
TH_4621|M.thermoresistible__bu      HSATGGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRSTA
MSMEG_4727|M.smegmatis_MC2_155      HSATGGVGQAAIAVARAAGAEIYATAGSEKRRQLLRDWGIEHVYDSRTTA
MAB_3148c|M.abscessus_ATCC_199      HSGTGGVGQAAIAIARAAGAEIYATAGSPERRDLLRSWGIKHVYDSRSTD
Mb2959|M.bovis_AF2122/97            --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02354|M.leprae_Br4923          --------------------------------------------------
MMAR_1773|M.marinum_M               --------------------------------------------------
MUL_2016|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3391|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

MAV_2370|M.avium_104                FADLIRHDTDGYGVDIVLNSVTGAAQRAGIELLAFGGRFVEIGKRDIYGD
TH_4621|M.thermoresistible__bu      FADEIRRDTDGYGVDVVLNSLPGAAQRAGLELLSFGGRFIEIGKRDIYGD
MSMEG_4727|M.smegmatis_MC2_155      FADQIRTDTDGYGVDIVLNSVTGPAQRAGLELLAFGGRFVEIGKRDIYAD
MAB_3148c|M.abscessus_ATCC_199      FAELIRRDTDGYGVDIVLNSLTGAAQRAGVELLTFGGRFIEIGKRDIYGD
Mb2959|M.bovis_AF2122/97            --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02354|M.leprae_Br4923          --------------------------------------------------
MMAR_1773|M.marinum_M               --------------------------------------------------
MUL_2016|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3391|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

MAV_2370|M.avium_104                TRLGLLPFRRNLTFYALDLALMSFSHPDRLRGLLRTVYRLTADGALPMPE
TH_4621|M.thermoresistible__bu      TRLGLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADGVLPMPQ
MSMEG_4727|M.smegmatis_MC2_155      TRLGLFPFRRNLSFYAVDLALMTVTHPQKIRDLLATVYRLIADGTLPLPE
MAB_3148c|M.abscessus_ATCC_199      TRLGLFPFRRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEGVLPLPE
Mb2959|M.bovis_AF2122/97            --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02354|M.leprae_Br4923          --------------------------------------------------
MMAR_1773|M.marinum_M               --------------------------------------------------
MUL_2016|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3391|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

MAV_2370|M.avium_104                STHYPLADAASAIRVMSAAQHTGKLVLDVPHAGRSRVVVPPAQVRAFRSD
TH_4621|M.thermoresistible__bu      STHYPLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSD
MSMEG_4727|M.smegmatis_MC2_155      ITHYPLEEAATAIRIMGGAQHTGKLVIDIPDTGQSQVVVPPEQVPVFRGD
MAB_3148c|M.abscessus_ATCC_199      ISPSPLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIPPSHAPAFRRD
Mb2959|M.bovis_AF2122/97            -----------------------------------------KGHPVVRQG
Rv2934|M.tuberculosis_H37Rv         -----------------------------------------KGHPVVRQG
MLBr_02354|M.leprae_Br4923          -----------------------------------------KDNPVVRPG
MMAR_1773|M.marinum_M               -----------------------------------------QRDPVIRPG
MUL_2016|M.ulcerans_Agy99           -----------------------------------------QRDPVIRPG
Mflv_3391|M.gilvum_PYR-GCK          -----------------------------------------PGRLQVRGD
Mvan_3124|M.vanbaalenii_PYR-1       -----------------------------------------PGQLVVRRD
                                                                                  .* .

MAV_2370|M.avium_104                GAYIVTGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALPNPKALATLER
TH_4621|M.thermoresistible__bu      GAYIVTGGMGGLGLYLAGEMAAAG--AGC--IVLNGRSAPSGEALRTIEQ
MSMEG_4727|M.smegmatis_MC2_155      GAYVITGGLGGLGLFLAERMAAAG----CGRIVVNSRSAPSTRSSEIIEL
MAB_3148c|M.abscessus_ATCC_199      GAYVVTGGLGGLGLFLARKLAAAG----VGRIILNGRSAPKPEALAAIEQ
Mb2959|M.bovis_AF2122/97            ASYVVTGGLGGLGLVVARWLVDRG----AGRVVLGGRSDPTDEQCNVLAE
Rv2934|M.tuberculosis_H37Rv         ASYVVTGGLGGLGLVVARWLVDRG----AGRVVLGGRSDPTDEQCNVLAE
MLBr_02354|M.leprae_Br4923          AAYIVTGGLGGLGLVVARWLVDRG----AGRVVLGSRSDPTEEQRKTLVE
MMAR_1773|M.marinum_M               ASYIVTGGLGGLGLVVARWLVDSG----AGRVVLNGRSEPSDEQRKVLAE
MUL_2016|M.ulcerans_Agy99           ASYIVTGGLGGLGLVVARWLVDSG----AGRVVLNGRSEPSDEQRKVLAE
Mflv_3391|M.gilvum_PYR-GCK          GSYVVTGALGGVGLAVVRWLVDHG----AGRLVLNGRSGPSPEAQAVIDE
Mvan_3124|M.vanbaalenii_PYR-1       GAYVVTGALGGVGMAVVRWLVDHG----AGRLVLNGRSGPSDEVAAELDT
                                    .:*::**.:**:*: :.  :.  *       ::: .*: *. .    :  

MAV_2370|M.avium_104                IRQMGADIVVERGDIAEAGTAQRLLDVATATGLPVRGVLHLAAVIEDATL
TH_4621|M.thermoresistible__bu      LRAAGTEVIVECGXXXRG----QPVEVAVPT------ELRHADEHPDRRG
MSMEG_4727|M.smegmatis_MC2_155      IRATGADIVVECGDIAEPDTALRLVAAATQTGLPLRGVLHAAAVVEDATL
MAB_3148c|M.abscessus_ATCC_199      IRQGGTEIDVALGDIAEPDTAQRLVAAATETGKPVRGVLHAAALVHDATL
Mb2959|M.bovis_AF2122/97            LQTR-AEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLV
Rv2934|M.tuberculosis_H37Rv         LQTR-AEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLV
MLBr_02354|M.leprae_Br4923          LEAR-AEIVFLRGDVTSPGVAESLVAAAGRAGGQLRGIVHGAAVIEDSLV
MMAR_1773|M.marinum_M               LESR-AEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLL
MUL_2016|M.ulcerans_Agy99           LESR-AEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLL
Mflv_3391|M.gilvum_PYR-GCK          LSAR-AEIAVVTGDIAVPGTAVRLIAAAEETGRPLRGVLHSAAVLDDELV
Mvan_3124|M.vanbaalenii_PYR-1       LSHR-AEIAVVTGDVAEPGVAERLVAAAEETGKPLRGLIHSAAVLEDEIF
                                    :    ::: .  *           : .*          :: *    *   

MAV_2370|M.avium_104                ANITDELIER-DWAAKVYGAWNLHCALQESG-AEQSLDWFCSFSSAAALV
TH_4621|M.thermoresistible__bu      AQLCDEFARG-EQGAQR----NQHRTDAGEG-QRD--------AHPPGAV
MSMEG_4727|M.smegmatis_MC2_155      ANITDELVEH-DWAPKVYGAWNLHQAVQSGGPATSELDWFCAFSSAAALV
MAB_3148c|M.abscessus_ATCC_199      ANITDELIDRGDWRPKVHGAWNLHEATADQP-----LDWFCSFSSIAALV
Mb2959|M.bovis_AF2122/97            FSMSRDNLER-VWAPKATGALRMHEATADCE-----LDWWLGFSSAASLL
Rv2934|M.tuberculosis_H37Rv         FSMSRDNLER-VWAPKATGALRMHEATADCE-----LDWWLGFSSAASLL
MLBr_02354|M.leprae_Br4923          FTMTRENLER-VWAPKATGALRMHQASVSCE-----LDWWLGFSSVASLL
MMAR_1773|M.marinum_M               FSMTKDSLER-VWAPKAAGALRLHDATATRE-----LDWWLGFSSTASLL
MUL_2016|M.ulcerans_Agy99           FSMTKDSLER-VWAPKAAGALRLHDATATRE-----LDWWLGFSSTASLL
Mflv_3391|M.gilvum_PYR-GCK          VGLTRESMEK-IWAPKAAGAWRLHEATAGKE-----LDWWVAFSSVASLL
Mvan_3124|M.vanbaalenii_PYR-1       VGMTRESLDK-IWAPKAAGALRLHEVTAGSD-----LDWWVGFSSIVSLL
                                      :  :        .:     . * .                 :   . :

MAV_2370|M.avium_104                GSPGQGAYAAANSWLDAFTRWRRARGLKATAIAWGAWAQIGRGAALADSA
TH_4621|M.thermoresistible__bu      GHDQPDPGALSDTGLDERGGQFPGVGVQIPVADPGVGIDH-RGAVRVDSG
MSMEG_4727|M.smegmatis_MC2_155      GSPGQGAYAAANSWLDAFMQWRRAQGLPATSIAWGAWGEIGRGTAMAE-G
MAB_3148c|M.abscessus_ATCC_199      GSPGQGAYAAANSWLDGFTHWRRAQGLPATVIAWGAWSEIGQGTHLAQNA
Mb2959|M.bovis_AF2122/97            GSPGQAAYACASAWLDALVGWRRASGLPAAVINWGPWSEVGVAQALVGSV
Rv2934|M.tuberculosis_H37Rv         GSPGQAAYACASAWLDALVGWRRASGLPAAVINWGPWSEVGVAQALVGSV
MLBr_02354|M.leprae_Br4923          GSPGQAAYACASAWLDALVMWRKASGLPSAVINWGPWSDVGVAQALVGSV
MMAR_1773|M.marinum_M               GSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQALVGTP
MUL_2016|M.ulcerans_Agy99           GSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQALVGTP
Mflv_3391|M.gilvum_PYR-GCK          GSPGQSAYACANAWLDALVTWRAAAGLPATTVNWGQWADVGLASSLRFSV
Mvan_3124|M.vanbaalenii_PYR-1       GSPGQAAYACANAWLDGLVAWRTAAGLPALAVNWGQWADVGLASTLRFSV
                                    *     . * :.: **       . *:       *   :   .       

MAV_2370|M.avium_104                DVAITPDEGAYAFEALLRHDRACTGYAPITGTPWLTAFAQRSPFAEAFRA
TH_4621|M.thermoresistible__bu      VPAQQGVDGEVVRHRTLSSVRSGR-------SSRWTAPGSR--CGSGRRY
MSMEG_4727|M.smegmatis_MC2_155      DNAIAPDEGAYAFEAILRHDRVYNGYAPVLGASWLTAFAQRSPFAELFLA
MAB_3148c|M.abscessus_ATCC_199      EAAILPDEGAYAFDTVLRHNRAYTAYAPMAGISWLADFVERSPFAQAFRD
Mb2959|M.bovis_AF2122/97            LDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPEIRSISYFTQV
Rv2934|M.tuberculosis_H37Rv         LDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPEIRSISYFTQV
MLBr_02354|M.leprae_Br4923          LDTITPAEGIEAIDSLLAAGRTRTGVARLRADKALVAFPEMRSISYFTWV
MMAR_1773|M.marinum_M               LDPITPAEGVVALDALLAADRGRTGVARLRSDRALIAFPEIRNLGYFTLV
MUL_2016|M.ulcerans_Agy99           LDPITPAEGLVALDALLAADRGRTGVARLRSDRALIAFPEIRNLGYFTLV
Mflv_3391|M.gilvum_PYR-GCK          LDPITPDEGVEALGGVMAAGLTRVGIARLRLDRAAAAFPEIQQIGFFADL
Mvan_3124|M.vanbaalenii_PYR-1       LDPITPAEGVEALGGVMAAGFSRVGIARLRLDRAAAAFPEIQQIGFFADL
                                      .    :*  .    :                      .    .     

MAV_2370|M.avium_104                NGQSATGTS--------KLRAELEELPPEEWSTRLRRLISDQVSLILRRN
TH_4621|M.thermoresistible__bu      GGESCRRTT--------GPAAGAAARRGR-----------------TRRR
MSMEG_4727|M.smegmatis_MC2_155      DTQGASETR--------KLRSELAALPREEWPTHLRRLIAEQVGLLLRRT
MAB_3148c|M.abscessus_ATCC_199      AGQNQTETN--------KFLDELRALPREEWPTRLRKLVAEQVGLVLRRS
Mb2959|M.bovis_AF2122/97            VEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQST
Rv2934|M.tuberculosis_H37Rv         VEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQST
MLBr_02354|M.leprae_Br4923          VEQLAAAGDLGDWVGSDTLADLDPAEAQRVVTERMCALIAAVMGYADRST
MMAR_1773|M.marinum_M               VQELDAAGDGGDWAGPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSA
MUL_2016|M.ulcerans_Agy99           VQELDAAGDGGDWAGPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSA
Mflv_3391|M.gilvum_PYR-GCK          VSELDTDDADDDWEGAEALKTMSAAEINRVVVARLRRRIAGVMGYSNDSA
Mvan_3124|M.vanbaalenii_PYR-1       VGELETDDVDEDWGGVEALKSMDAAEVNRVVVARLRRRISAIMGYSDDNA
                                      :                         .                     

MAV_2370|M.avium_104                VDPDRP----LPEYGLDSLGGLELLTRIQTETGIRVSPADIAAIGTIRGL
TH_4621|M.thermoresistible__bu      RRPRRP----PPPP-----------DRVRHRAGP--------AHGPVRR-
MSMEG_4727|M.smegmatis_MC2_155      VDPDRP----LSEYGLDSLGHLELRTRIETETGVRVS---AMDMTTIRGL
MAB_3148c|M.abscessus_ATCC_199      IDPDRS----LPDYGLDSLGNLEIRTRIQADTGVRIG---PADVSTVRSL
Mb2959|M.bovis_AF2122/97            VEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDL
Rv2934|M.tuberculosis_H37Rv         VEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDL
MLBr_02354|M.leprae_Br4923          VNPAVP----LTELGLDSLMAVRIRNGARADFGVEPPVTLILQGASLQDL
MMAR_1773|M.marinum_M               VDASMP----LTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDL
MUL_2016|M.ulcerans_Agy99           VDASMP----LTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDL
Mflv_3391|M.gilvum_PYR-GCK          VDTAKP----LTEMGLDSLMAVRMRNTIRGDFGVEPPVALLLQGATLNDV
Mvan_3124|M.vanbaalenii_PYR-1       VDTAQP----LTELGLDSLMAVRMRNTIRGDFGVEPPVALLLQGATLADL
                                      .  .     .                .   *            .:   

MAV_2370|M.avium_104                ADLLRDKLTPAGAAQAERV-------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      AQRLCEMLDTDDAVSAPS--------------------------------
MAB_3148c|M.abscessus_ATCC_199      AAHIYDRLAEQESEVASS--------------------------------
Mb2959|M.bovis_AF2122/97            TADLMRQLGLNDPDPALNNADTIRDRARQRAAARHGAAMRRRPKPAVQGG
Rv2934|M.tuberculosis_H37Rv         TADLMRQLGLNDPDPALNNADTIRDRARQRAAARHGAAMRRRPKPEVQGG
MLBr_02354|M.leprae_Br4923          TADVVRQLGLAGPKQALENADTVRDRVQQRAAVRRGAVMRRRPKPDVQGG
MMAR_1773|M.marinum_M               TVDVIRQLDLAGDEQTHEHVDVVRDRAQQRAAARHGAAMRRKRG------
MUL_2016|M.ulcerans_Agy99           TVDVIRQLDLAGDEQTHEHVDVVRDRAQQRAAARHGAAMRRKRG------
Mflv_3391|M.gilvum_PYR-GCK          ALDLIRQLGLA-EEDGSDRPNALRDRAQQRAAARQRAASRRKVGPRS---
Mvan_3124|M.vanbaalenii_PYR-1       ALDLIRQLGLE-EQESAERPNALRERAQQRAAARQRAASRRKVGPRS---