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MTTVSRAVAGPADDISVGPGLSSAPARRRRGTLRRIVTQWGPAVPFLIAAGGILAAAAFWLIRTSFSGPD GGWTLQAWQDIFAQQITRAAMVRSLGLSAVVATLCLVLGSVLAYLVSGLARRGRTAAQALLNVAANFGGA SLAIAMVSTLGAVGFVRLLLQDRFGYALGFDLYSFWGVVVTYMYFILPLYVLLVLPAMSVLRAEWWDAVQ AAGGTRWHYWRHVGLPVLCPFLLAGWVLTFAWSLGQFSVPYALLGDTSATSLITTRLGNFLFSATGGSNR FERAAALAVFLMVISALALVLYRLIANRMLARLENLR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6669 | - | - | 100% (317) | ABC transporter, permease protein |
M. smegmatis MC2 155 | MSMEG_6523 | - | 6e-27 | 31.45% (283) | ABC transporter, membrane spanning protein |
M. smegmatis MC2 155 | MSMEG_4763 | - | 5e-12 | 25.24% (309) | ABC transporter permease protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1269 | sugB | 3e-11 | 24.59% (244) | sugar-transport integral membrane protein ABC transporter |
M. gilvum PYR-GCK | Mflv_1081 | - | 2e-28 | 31.71% (287) | binding-protein-dependent transport systems inner membrane |
M. tuberculosis H37Rv | Rv1237 | sugB | 3e-11 | 24.59% (244) | sugar-transport integral membrane protein ABC transporter |
M. leprae Br4923 | MLBr_01088 | - | 8e-11 | 23.77% (244) | putative ABC-transport protein, inner membrane component |
M. abscessus ATCC 19977 | MAB_1503 | - | 1e-15 | 25.66% (304) | ABC transporter permease |
M. marinum M | MMAR_3717 | cysT | 9e-12 | 26.25% (259) | sulfate-transport integral membrane protein ABC transporter |
M. avium 104 | MAV_1783 | cysT | 5e-12 | 26.01% (323) | sulfate ABC transporter, permease protein CysT |
M. thermoresistible (build 8) | TH_1446 | cysT | 8e-14 | 27.56% (254) | PROBABLE SULFATE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC |
M. ulcerans Agy99 | MUL_3660 | cysT | 3e-12 | 26.71% (307) | sulfate-transport integral membrane protein ABC transporter |
M. vanbaalenii PYR-1 | Mvan_5733 | - | 1e-141 | 79.81% (317) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_6669|M.smegmatis_MC2_155 MTTVSRAVAGPADDISVGPGLSSAPARRRRGTLRRIVTQWGPAVPFLIAA Mvan_5733|M.vanbaalenii_PYR-1 MTVTTPTAPGPA----VTPPAAGPPPR--PGPLRTFLTQWGPAIPFLVTA MMAR_3717|M.marinum_M MTVTAHSGQSDPPAVAPDPGQRADGGPQWISGLGRSGRRGATALQVGVSM MUL_3660|M.ulcerans_Agy99 MTVTAHSGQSDPPAVAPDLGQRADGGPQWISGPGRSGRRGATALQVGVSM MAV_1783|M.avium_104 MTAITP----DPLAIRPELG--GDPGHQPVPGRGR----GTTALRVGVAT TH_1446|M.thermoresistible__bu -----------VSAVLP----RSETTPAAPPGWGRG---GATSLRVGIAT Mb1269|M.bovis_AF2122/97 -------------------------------MGARRATYWAVLDTLVVGY Rv1237|M.tuberculosis_H37Rv -------------------------------MGARRATYWAVLDTLVVGY MLBr_01088|M.leprae_Br4923 ------------------MGIEKVKVTAGVRVGARRATIWVIIDTFVVGY Mflv_1081|M.gilvum_PYR-GCK ------------------------------MSLARRLRDSLPLLPFLIVV MAB_1503|M.abscessus_ATCC_1997 ------------------MIAVLDRVDSAGAQPRRKRRRAVPVLWAIPPL MSMEG_6669|M.smegmatis_MC2_155 GGILAAAAFWLIRTSFSGPDGGWTL------QAWQDIFAQQITRAAMVRS Mvan_5733|M.vanbaalenii_PYR-1 GGLLVAAALWLIRTSFAGPDGGWTL------QAWQDIFTQRITRDAMVRS MMAR_3717|M.marinum_M VWLSVIVLLPLAAIAWQAADGGW--------HAFWLSVSSHAALESLRVT MUL_3660|M.ulcerans_Agy99 VWLSVIVLLPLAAIAWQAADGGW--------HAFWLSVSSHAALESLRVT MAV_1783|M.avium_104 VWLSVIVLLPLAAIAWQSAGGGW--------HVFWLAVTSNAALESFRVT TH_1446|M.thermoresistible__bu VWLSIIVLLPLAAILWQSTNGGW--------DAFRDAVTANAALTSLRVT Mb1269|M.bovis_AF2122/97 ALLPVLWIFSLSLKPTSTVKDGKLIPSTVTFDNYRGIFRGDLFSSALINS Rv1237|M.tuberculosis_H37Rv ALLPVLWIFSLSLKPTSTVKDGKLIPSTVTFDNYRGIFRGDLFSSALINS MLBr_01088|M.leprae_Br4923 ALLPVLWILSLSLKPASTVKDGKLIPSLVTFDNYRGIFRSDLFSSALINS Mflv_1081|M.gilvum_PYR-GCK VIFLIIPTVTVVIGAVYS-DGVFS-------LDRIAALFTGTALSALADS MAB_1503|M.abscessus_ATCC_1997 LVVLVAIVYPLLRVLSDSAEGEGN-------STWRAVLGSTLFQHALVTT . : . . :: : MSMEG_6669|M.smegmatis_MC2_155 LGLSAVVATLCLVLGSVLAYLVSG--LARRGRTAAQALLNVAANFGGASL Mvan_5733|M.vanbaalenii_PYR-1 LGLSAIVATFCLVVGSVLAYLISG--LARRGRAGAQALLNVAANFGGASL MMAR_3717|M.marinum_M LTVSAGVTLLNTVFGLLIAWVLIR--DEFVGKRLVDAVIDLPFALPTIVA MUL_3660|M.ulcerans_Agy99 LTVSAGVTLLNAVFGLLIAWGLIR--DEFVGKRLVDAVIDLPFALPTIVA MAV_1783|M.avium_104 LTISAGVTVLNLVFGLVIAWVLVR--DEFPGKRLVDAIIDLPFALPTIVA TH_1446|M.thermoresistible__bu LTIAAGVTVVNTVFGLMVAWVLTR--DEFIGKRLVNSVIDLPFALPTIVA Mb1269|M.bovis_AF2122/97 IGIGLITTVIAVVLGAMAAYAVAR--LEFPGKRLLIGAALLITMFPSISL Rv1237|M.tuberculosis_H37Rv IGIGLITTVIAVVLGAMAAYAVAR--LEFPGKRLLIGAALLITMFPSISL MLBr_01088|M.leprae_Br4923 IGIGLTTTVIAVMFGAMAAYAIAR--LAFPGKRLLVGTTLLVTMFPAISL Mflv_1081|M.gilvum_PYR-GCK VLLSGSTALIGAFLGAVMAWLIISSPPASMLRRAVLSLCSVLAQFGGVAL MAB_1503|M.abscessus_ATCC_1997 VYIAVLTTIGCLALGTFLATVLAF--VPFPGSELVGRLIDTVLALPSFLI : :. .: .* . * : : MSMEG_6669|M.smegmatis_MC2_155 AIAMVSTLGAVGFVRLLLQDRFGYALGFD--LYSFWGVVVTYMYFILPLY Mvan_5733|M.vanbaalenii_PYR-1 AIAMVSTLGAVGFVRLLLENWFGYQLGLD--LYSVWGLVVTYIYFILPLY MMAR_3717|M.marinum_M SLVMLALYGHNSPLGLHLQ-------------HTVWGVGVALAFVTLPFV MUL_3660|M.ulcerans_Agy99 SLVMLALYGHNSPLGLHLQ-------------HTVWGVGVALAFVTLPFV MAV_1783|M.avium_104 SLVMLALYGNNSPVGLHLQ-------------HTAAGVAVALAFVTLPFV TH_1446|M.thermoresistible__bu SLVMLALYGPASPVDIHLQ-------------HTRWGVGVALLFVTLPFV Mb1269|M.bovis_AF2122/97 VTPLFNIERAIGLFDTWPG------------------LILPYITFALPLA Rv1237|M.tuberculosis_H37Rv VTPLFNIERAIGLFDTWPG------------------LILPYITFALPLA MLBr_01088|M.leprae_Br4923 VTPLFNIERRVGLFDTWAG------------------LILPYITFALPLA Mflv_1081|M.gilvum_PYR-GCK AFAFLATVGLNGVLTLWVQQAFGFNLAGSGWLYSLAGLTLVYTYFQIPLM MAB_1503|M.abscessus_ATCC_1997 TLAFTFLYGAAGAVNALIANLTG-GSRPLEFLSSPAGVILAETTFFTPFV : . . : : . *: MSMEG_6669|M.smegmatis_MC2_155 VLLVLPAMSVLRAEWWDAVQAAGGTRWHYWRHVGLPVLCPFLLAGWVLTF Mvan_5733|M.vanbaalenii_PYR-1 VLLVLPAMSVLRPEWWEAVQTAGGTRWQYWRRVGLPVLFPFLLSGWVLTF MMAR_3717|M.marinum_M VRAVQPVLLELDRETEEAAASLGATGWKVFTSVIFPSLMPALLSGAGLAF MUL_3660|M.ulcerans_Agy99 VRAVQPVLLELDRETEEAAASLGATGWKVFTSVIFPSLMPALLSGAGLAF MAV_1783|M.avium_104 VRAVQPVLLELDRETEEAAASLGASGPKIFTSVVLPALLPALLSGAGLAF TH_1446|M.thermoresistible__bu VRSVQPVLLELDRETEEAAASLGANNLTIFTRVVLPALLPALLSGAGLAF Mb1269|M.bovis_AF2122/97 IYTLSAFFREIPWDLEKAAKMDGATPGQAFRKVIVPLAAPGLVTAAILVF Rv1237|M.tuberculosis_H37Rv IYTLSAFFREIPWDLEKAAKMDGATPGQAFRKVIVPLAAPGLVTAAILVF MLBr_01088|M.leprae_Br4923 IYTLSAFFAEIPWDLEKAAKMDGATSGQAFRKVIVPLAAPGLVTAAILVF Mflv_1081|M.gilvum_PYR-GCK VIVFIPALEGLRGQWREAAVSLGASTWAYWREVAIPLLTPAFLGSALLLF MAB_1503|M.abscessus_ATCC_1997 VRPLLAAFVIVPREQLDVAASLGASPWRVLAKVVMPEAWPALMAGGSLVL : . . : : : ... *.. * .* * :: . * : MSMEG_6669|M.smegmatis_MC2_155 AWSLGQFSVPYALLGDTSATSLITTRLGNFLFSATGGSNRFERAAALAVF Mvan_5733|M.vanbaalenii_PYR-1 AWSLGQFSVPYALLGDTTTTSLITTRLGNFLFSATGGTNRFERAAALAVL MMAR_3717|M.marinum_M SRAIGEFGSVVLIGGAVPGETEVSSQWIRTLIENDDRTG----AAAISIV MUL_3660|M.ulcerans_Agy99 SRAIGEFGSVVLIGGAVPGETEVSSQWIRTLIENDDRTG----AAAISIV MAV_1783|M.avium_104 SRAIGEFGSVVLIGGAVPGKTEVSSQWIRTLIENDDRTG----AAAISIV TH_1446|M.thermoresistible__bu SRAIGEFGSVVLIGGAVPGETEVASQWIRTLIENDDRTG----AAAVSIV Mb1269|M.bovis_AF2122/97 IFAWNDLLLALSLTATKAAITAPVAIANFTGSSQFEEPTGSIAAGAIVIT Rv1237|M.tuberculosis_H37Rv IFAWNDLLLALSLTATKAAITAPVAIANFTGSSQFEEPTGSIAAGAIVIT MLBr_01088|M.leprae_Br4923 IFAWNDLLLALSLTSTKAAITAPVAITNFTGSSQFEEPTGSIAAGAIVIT Mflv_1081|M.gilvum_PYR-GCK ANAFAAYATAAALVSQGSPILPLLIRASLVSEVVLGQAG---FAYALALE MAB_1503|M.abscessus_ATCC_1997 LLALNEFG-IVLFTGAKEVVTLPVLIYTRGIVTFDLPGAAVIATIQIVLS : : . : : : MSMEG_6669|M.smegmatis_MC2_155 LMVISALALVLYRLIANRMLARLENLR Mvan_5733|M.vanbaalenii_PYR-1 LMVISALALVAYRRIAARMLARLEGLR MMAR_3717|M.marinum_M LLSISFAVLLVLRVLGARAAKREELAP MUL_3660|M.ulcerans_Agy99 LLSISFAVLLVLRVLGARAAKREELAP MAV_1783|M.avium_104 LLAISFVVLLILRVVGGRAAKREELAA TH_1446|M.thermoresistible__bu LLVISFLVLLVLRVIGSRAAKREEQTA Mb1269|M.bovis_AF2122/97 IPIIVFVLIFQRRIVAGLTSGAVKG-- Rv1237|M.tuberculosis_H37Rv IPIIVFVLIFQRRIVAGLTSGAVKG-- MLBr_01088|M.leprae_Br4923 APIIVFVWIFQRRIVAGLTSGAVKG-- Mflv_1081|M.gilvum_PYR-GCK MIVVVAVVMVAYNLLVRRSSRWLT--- MAB_1503|M.abscessus_ATCC_1997 LALYGLYRIVFSRMLAGRANSEPKGA- :. . :