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TVTTPTAPGPAVTPPAAGPPPRPGPLRTFLTQWGPAIPFLVTAGGLLVAAALWLIRTSFAGPDGGWTLQA WQDIFTQRITRDAMVRSLGLSAIVATFCLVVGSVLAYLISGLARRGRAGAQALLNVAANFGGASLAIAMV STLGAVGFVRLLLENWFGYQLGLDLYSVWGLVVTYIYFILPLYVLLVLPAMSVLRPEWWEAVQTAGGTRW QYWRRVGLPVLFPFLLSGWVLTFAWSLGQFSVPYALLGDTTTTSLITTRLGNFLFSATGGTNRFERAAAL AVLLMVISALALVAYRRIAARMLARLEGLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5733 | - | - | 100% (311) | binding-protein-dependent transport systems inner membrane component |
| M. vanbaalenii PYR-1 | Mvan_5741 | - | 2e-28 | 32.12% (274) | binding-protein-dependent transport systems inner membrane |
| M. vanbaalenii PYR-1 | Mvan_2542 | - | 2e-15 | 27.44% (266) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1269 | sugB | 3e-12 | 25.42% (240) | sugar-transport integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_1081 | - | 4e-28 | 31.87% (273) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv1237 | sugB | 3e-12 | 25.42% (240) | sugar-transport integral membrane protein ABC transporter |
| M. leprae Br4923 | MLBr_01088 | - | 1e-10 | 23.75% (240) | putative ABC-transport protein, inner membrane component |
| M. abscessus ATCC 19977 | MAB_1503 | - | 7e-14 | 24.05% (291) | ABC transporter permease |
| M. marinum M | MMAR_3717 | cysT | 2e-14 | 27.41% (321) | sulfate-transport integral membrane protein ABC transporter |
| M. avium 104 | MAV_1783 | cysT | 7e-12 | 25.88% (313) | sulfate ABC transporter, permease protein CysT |
| M. smegmatis MC2 155 | MSMEG_6669 | - | 1e-141 | 79.81% (317) | ABC transporter, permease protein |
| M. thermoresistible (build 8) | TH_1446 | cysT | 4e-15 | 28.29% (304) | PROBABLE SULFATE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC |
| M. ulcerans Agy99 | MUL_3660 | cysT | 2e-14 | 28.88% (322) | sulfate-transport integral membrane protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5733|M.vanbaalenii_PYR-1 MTVTTPTAPGPA----VTPPAAGPPPRP--GPLRTFLTQWGPAIPFLVTA
MSMEG_6669|M.smegmatis_MC2_155 MTTVSRAVAGPADDISVGPGLSSAPARRRRGTLRRIVTQWGPAVPFLIAA
MMAR_3717|M.marinum_M MTVTAHSGQSDPPAVAPDPGQRADGGPQWISGLGRSGRRGATALQVGVSM
MUL_3660|M.ulcerans_Agy99 MTVTAHSGQSDPPAVAPDLGQRADGGPQWISGPGRSGRRGATALQVGVSM
MAV_1783|M.avium_104 MTAITP----DPLAIRPELG--GDPGHQPVPGRGR----GTTALRVGVAT
TH_1446|M.thermoresistible__bu -----------VSAVLP----RSETTPAAPPGWGRG---GATSLRVGIAT
Mb1269|M.bovis_AF2122/97 -------------------------------MGARRATYWAVLDTLVVGY
Rv1237|M.tuberculosis_H37Rv -------------------------------MGARRATYWAVLDTLVVGY
MLBr_01088|M.leprae_Br4923 ------------------MGIEKVKVTAGVRVGARRATIWVIIDTFVVGY
Mflv_1081|M.gilvum_PYR-GCK ------------------------------MSLARRLRDSLPLLPFLIVV
MAB_1503|M.abscessus_ATCC_1997 ------------------MIAVLDRVDSAGAQPRRKRRRAVPVLWAIPPL
Mvan_5733|M.vanbaalenii_PYR-1 GGLLVAAALWLIRTSFAGPDGGWTL------QAWQDIFTQRITRDAMVRS
MSMEG_6669|M.smegmatis_MC2_155 GGILAAAAFWLIRTSFSGPDGGWTL------QAWQDIFAQQITRAAMVRS
MMAR_3717|M.marinum_M VWLSVIVLLPLAAIAWQAADGGW--------HAFWLSVSSHAALESLRVT
MUL_3660|M.ulcerans_Agy99 VWLSVIVLLPLAAIAWQAADGGW--------HAFWLSVSSHAALESLRVT
MAV_1783|M.avium_104 VWLSVIVLLPLAAIAWQSAGGGW--------HVFWLAVTSNAALESFRVT
TH_1446|M.thermoresistible__bu VWLSIIVLLPLAAILWQSTNGGW--------DAFRDAVTANAALTSLRVT
Mb1269|M.bovis_AF2122/97 ALLPVLWIFSLSLKPTSTVKDGKLIPSTVTFDNYRGIFRGDLFSSALINS
Rv1237|M.tuberculosis_H37Rv ALLPVLWIFSLSLKPTSTVKDGKLIPSTVTFDNYRGIFRGDLFSSALINS
MLBr_01088|M.leprae_Br4923 ALLPVLWILSLSLKPASTVKDGKLIPSLVTFDNYRGIFRSDLFSSALINS
Mflv_1081|M.gilvum_PYR-GCK VIFLIIPTVTVVIGAVYS-DGVFS-------LDRIAALFTGTALSALADS
MAB_1503|M.abscessus_ATCC_1997 LVVLVAIVYPLLRVLSDSAEGEGN-------STWRAVLGSTLFQHALVTT
. : . . :: :
Mvan_5733|M.vanbaalenii_PYR-1 LGLSAIVATFCLVVGSVLAYLISG--LARRGRAGAQALLNVAANFGGASL
MSMEG_6669|M.smegmatis_MC2_155 LGLSAVVATLCLVLGSVLAYLVSG--LARRGRTAAQALLNVAANFGGASL
MMAR_3717|M.marinum_M LTVSAGVTLLNTVFGLLIAWVLIR--DEFVGKRLVDAVIDLPFALPTIVA
MUL_3660|M.ulcerans_Agy99 LTVSAGVTLLNAVFGLLIAWGLIR--DEFVGKRLVDAVIDLPFALPTIVA
MAV_1783|M.avium_104 LTISAGVTVLNLVFGLVIAWVLVR--DEFPGKRLVDAIIDLPFALPTIVA
TH_1446|M.thermoresistible__bu LTIAAGVTVVNTVFGLMVAWVLTR--DEFIGKRLVNSVIDLPFALPTIVA
Mb1269|M.bovis_AF2122/97 IGIGLITTVIAVVLGAMAAYAVAR--LEFPGKRLLIGAALLITMFPSISL
Rv1237|M.tuberculosis_H37Rv IGIGLITTVIAVVLGAMAAYAVAR--LEFPGKRLLIGAALLITMFPSISL
MLBr_01088|M.leprae_Br4923 IGIGLTTTVIAVMFGAMAAYAIAR--LAFPGKRLLVGTTLLVTMFPAISL
Mflv_1081|M.gilvum_PYR-GCK VLLSGSTALIGAFLGAVMAWLIISSPPASMLRRAVLSLCSVLAQFGGVAL
MAB_1503|M.abscessus_ATCC_1997 VYIAVLTTIGCLALGTFLATVLAF--VPFPGSELVGRLIDTVLALPSFLI
: :. .: .* . * : :
Mvan_5733|M.vanbaalenii_PYR-1 AIAMVSTLGAVGFVRLLLENWFGYQLGLD--LYSVWGLVVTYIYFILPLY
MSMEG_6669|M.smegmatis_MC2_155 AIAMVSTLGAVGFVRLLLQDRFGYALGFD--LYSFWGVVVTYMYFILPLY
MMAR_3717|M.marinum_M SLVMLALYGHNSPLGLHLQ-------------HTVWGVGVALAFVTLPFV
MUL_3660|M.ulcerans_Agy99 SLVMLALYGHNSPLGLHLQ-------------HTVWGVGVALAFVTLPFV
MAV_1783|M.avium_104 SLVMLALYGNNSPVGLHLQ-------------HTAAGVAVALAFVTLPFV
TH_1446|M.thermoresistible__bu SLVMLALYGPASPVDIHLQ-------------HTRWGVGVALLFVTLPFV
Mb1269|M.bovis_AF2122/97 VTPLFNIERAIGLFDTWPG------------------LILPYITFALPLA
Rv1237|M.tuberculosis_H37Rv VTPLFNIERAIGLFDTWPG------------------LILPYITFALPLA
MLBr_01088|M.leprae_Br4923 VTPLFNIERRVGLFDTWAG------------------LILPYITFALPLA
Mflv_1081|M.gilvum_PYR-GCK AFAFLATVGLNGVLTLWVQQAFGFNLAGSGWLYSLAGLTLVYTYFQIPLM
MAB_1503|M.abscessus_ATCC_1997 TLAFTFLYGAAGAVNALIANLTG-GSRPLEFLSSPAGVILAETTFFTPFV
: . . : : . *:
Mvan_5733|M.vanbaalenii_PYR-1 VLLVLPAMSVLRPEWWEAVQTAGGTRWQYWRRVGLPVLFPFLLSGWVLTF
MSMEG_6669|M.smegmatis_MC2_155 VLLVLPAMSVLRAEWWDAVQAAGGTRWHYWRHVGLPVLCPFLLAGWVLTF
MMAR_3717|M.marinum_M VRAVQPVLLELDRETEEAAASLGATGWKVFTSVIFPSLMPALLSGAGLAF
MUL_3660|M.ulcerans_Agy99 VRAVQPVLLELDRETEEAAASLGATGWKVFTSVIFPSLMPALLSGAGLAF
MAV_1783|M.avium_104 VRAVQPVLLELDRETEEAAASLGASGPKIFTSVVLPALLPALLSGAGLAF
TH_1446|M.thermoresistible__bu VRSVQPVLLELDRETEEAAASLGANNLTIFTRVVLPALLPALLSGAGLAF
Mb1269|M.bovis_AF2122/97 IYTLSAFFREIPWDLEKAAKMDGATPGQAFRKVIVPLAAPGLVTAAILVF
Rv1237|M.tuberculosis_H37Rv IYTLSAFFREIPWDLEKAAKMDGATPGQAFRKVIVPLAAPGLVTAAILVF
MLBr_01088|M.leprae_Br4923 IYTLSAFFAEIPWDLEKAAKMDGATSGQAFRKVIVPLAAPGLVTAAILVF
Mflv_1081|M.gilvum_PYR-GCK VIVFIPALEGLRGQWREAAVSLGASTWAYWREVAIPLLTPAFLGSALLLF
MAB_1503|M.abscessus_ATCC_1997 VRPLLAAFVIVPREQLDVAASLGASPWRVLAKVVMPEAWPALMAGGSLVL
: . . : : : ... *.. * .* * :: . * :
Mvan_5733|M.vanbaalenii_PYR-1 AWSLGQFSVPYALLGDTTTTSLITTRLGNFLFSATGGTNRFERAAALAVL
MSMEG_6669|M.smegmatis_MC2_155 AWSLGQFSVPYALLGDTSATSLITTRLGNFLFSATGGSNRFERAAALAVF
MMAR_3717|M.marinum_M SRAIGEFGSVVLIGGAVPGETEVSSQWIRTLIENDDRTG----AAAISIV
MUL_3660|M.ulcerans_Agy99 SRAIGEFGSVVLIGGAVPGETEVSSQWIRTLIENDDRTG----AAAISIV
MAV_1783|M.avium_104 SRAIGEFGSVVLIGGAVPGKTEVSSQWIRTLIENDDRTG----AAAISIV
TH_1446|M.thermoresistible__bu SRAIGEFGSVVLIGGAVPGETEVASQWIRTLIENDDRTG----AAAVSIV
Mb1269|M.bovis_AF2122/97 IFAWNDLLLALSLTATKAAITAPVAIANFTGSSQFEEPTGSIAAGAIVIT
Rv1237|M.tuberculosis_H37Rv IFAWNDLLLALSLTATKAAITAPVAIANFTGSSQFEEPTGSIAAGAIVIT
MLBr_01088|M.leprae_Br4923 IFAWNDLLLALSLTSTKAAITAPVAITNFTGSSQFEEPTGSIAAGAIVIT
Mflv_1081|M.gilvum_PYR-GCK ANAFAAYATAAALVSQGSPILPLLIRASLVSEVVLGQAG---FAYALALE
MAB_1503|M.abscessus_ATCC_1997 LLALNEFG-IVLFTGAKEVVTLPVLIYTRGIVTFDLPGAAVIATIQIVLS
: : . : : :
Mvan_5733|M.vanbaalenii_PYR-1 LMVISALALVAYRRIAARMLARLEGLR
MSMEG_6669|M.smegmatis_MC2_155 LMVISALALVLYRLIANRMLARLENLR
MMAR_3717|M.marinum_M LLSISFAVLLVLRVLGARAAKREELAP
MUL_3660|M.ulcerans_Agy99 LLSISFAVLLVLRVLGARAAKREELAP
MAV_1783|M.avium_104 LLAISFVVLLILRVVGGRAAKREELAA
TH_1446|M.thermoresistible__bu LLVISFLVLLVLRVIGSRAAKREEQTA
Mb1269|M.bovis_AF2122/97 IPIIVFVLIFQRRIVAGLTSGAVKG--
Rv1237|M.tuberculosis_H37Rv IPIIVFVLIFQRRIVAGLTSGAVKG--
MLBr_01088|M.leprae_Br4923 APIIVFVWIFQRRIVAGLTSGAVKG--
Mflv_1081|M.gilvum_PYR-GCK MIVVVAVVMVAYNLLVRRSSRWLT---
MAB_1503|M.abscessus_ATCC_1997 LALYGLYRIVFSRMLAGRANSEPKGA-
:. . :