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NRPAFLYPGQGSQRAGMIAALPPTSATRRVLDEASDALGGLGYLDTADGLASTRNAQLALLICGVAATRT LDEVYGVRPGVTAGHSAGAFAAAVAAGVLTFHEALDAVGVRAAAMEAACAPGEWGMAAVTGMGQRAAGAL VAEARATVWIANINAADQVVLGGTVDGLRDARAAARRMGARRFEMLDVAVASHGPVQARTATVIAERLAA VPRRHQSAAYLTNVGARRIVDDADAVLRDLAESVAKPVQWYDIAQVLPELGVQRTVEMPPGHVLTSLLAA VPVTATSVDDVGYAAISA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6629 | mdcH | - | 100% (299) | malonate decarboxylase, epsilon subunit |
M. smegmatis MC2 155 | MSMEG_4325 | - | 1e-13 | 30.20% (245) | malonyl CoA-acyl carrier protein transacylase |
M. smegmatis MC2 155 | MSMEG_4512 | - | 8e-12 | 31.31% (198) | polyketide synthetase mbtd |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2971c | pks1 | 5e-19 | 32.35% (306) | polyketide synthase PKS1 |
M. gilvum PYR-GCK | Mflv_2779 | - | 9e-20 | 31.32% (281) | (acyl-carrier protein) S-malonyltransferase |
M. tuberculosis H37Rv | Rv2946c | pks1 | 5e-19 | 32.35% (306) | polyketide synthase PKS1 |
M. leprae Br4923 | MLBr_01653 | fabD | 9e-17 | 29.08% (282) | malonyl CoA- |
M. abscessus ATCC 19977 | MAB_1879c | - | 1e-16 | 29.31% (290) | putative malonyl CoA-ACP transacylase FabD |
M. marinum M | MMAR_1762 | pks15/1 | 2e-18 | 31.49% (308) | polyketide synthase Pks15/1 |
M. avium 104 | MAV_2194 | - | 3e-19 | 30.36% (280) | malonyl CoA-acyl carrier protein transacylase |
M. thermoresistible (build 8) | TH_4621 | - | 6e-14 | 27.95% (297) | PUTATIVE mycocerosic acid synthase |
M. ulcerans Agy99 | MUL_2005 | pks15/1 | 2e-18 | 31.49% (308) | polyketide synthase Pks15/1 |
M. vanbaalenii PYR-1 | Mvan_3754 | - | 4e-20 | 31.76% (296) | (acyl-carrier protein) S-malonyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 MIEEQRTMSVEGADQQSEKLFHYLKKVAVELDETRARLREYEQRATEPVA Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M -----MTTSGESADQQNDKLFRYLKKVAVELDEARARLREYEQRATEPVA MUL_2005|M.ulcerans_Agy99 -----MTTSGESADQQNDKLFRYLKKVAVELDEARARLREYEQRATEPVA MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------VNIVGDTPVNAVA Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 VVGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDA Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M VVGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDA MUL_2005|M.ulcerans_Agy99 VVGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDA MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu VIGMACRLPGGIDSPQRLWEALLRGDDMVTEIPVDR-WDADDYFDPEPGV Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 EGKTYTRWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEH Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M EGKTYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEH MUL_2005|M.ulcerans_Agy99 EGKTYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEH MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu PGRTVSRWGAFLDDVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEH Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 AGIDPLSLRGSATGVYTGIFAASYGNRDTGG---LQGYGLTGTSISVASG Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M AGIDPMSLRGSSTGVFTGIFAPSYGGKDVGA---LQGYGLTGSPVSVASG MUL_2005|M.ulcerans_Agy99 AGIDPMSLRGSSTGVFTGIFAPSYGGKDVGA---LQGYGLTGSPVSVASG MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu AGLTPADVEGSSTGVFVGLSHDDYALLTSDAGALEEAYGFTGSAFSMASG Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 RVSYVLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMG Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M RVAYVLGLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMG MUL_2005|M.ulcerans_Agy99 RVAYVLGLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMG MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu RIAYRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVML Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRL Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRN MUL_2005|M.ulcerans_Agy99 LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRN MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu EPRKYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRD Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 GHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGLSAADVDV Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M GHNVLAVVRGSAINQDGASNGLTAPNGLAQQRVIQAALANCGLTSADVDV MUL_2005|M.ulcerans_Agy99 GHNVLAVVRGSAINQDGASNGLTAPNGLTQQRVIQAALANCGLTSADVDV MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu NDRILAVVRGTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGM Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 VEAHGTATTLGDPIEAQALLSTYGQGRPAEQPLWVGSIKSNMGHTQAAAG Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M VEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAG MUL_2005|M.ulcerans_Agy99 VEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAG MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu VEAHGTGTPVGDPIEYNSLTQVYGKTGP----CALTSVKTNFGHAESAAG Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 VAGVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREWSV-DG Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M VAGVIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AG MUL_2005|M.ulcerans_Agy99 VAGVIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AG MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu ALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREG Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 RPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVEASESTGGPRPSMVPW Rv2946c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1762|M.marinum_M RPRRAGVSSFGISGTNAHVILEEAPAP---EAVPDSESNKGEPSLPVVPW MUL_2005|M.ulcerans_Agy99 RPRRAGVSSFGISGTNAHVILEEAPAP---EAVPDSESNKGEPSLPVVPW MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu CPRRAAVSSYGMSGTNVHAVLEQAPEPVQRPEESADTDAAG-----PLVF Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 VISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSLASRSVFEHRAVVVG Rv2946c|M.tuberculosis_H37Rv MISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSLASRSVFEHRAVVVG MMAR_1762|M.marinum_M VISARSAEALTAQAGRLLAHVQADPQSNPVDIGFSLAGRSAFEHRAVVVG MUL_2005|M.ulcerans_Agy99 VISARSAEALTAQAGRLLAHVQADPQSNPVDIGFSLAGRSAFEHRAVVVG MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu ALSSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTV Mflv_2779|M.gilvum_PYR-GCK --------------------------MPQTTVLAFLAPGQGSQTPGMLTE Mvan_3754|M.vanbaalenii_PYR-1 --------------------------MPQTTVLAFLAPGQGSQTPGMLAE MAB_1879c|M.abscessus_ATCC_199 -------------------------------MIALLAPGQGSQTPGMLTP MLBr_01653|M.leprae_Br4923 -------------------------------MIALLAPGQGSQTEGMLSP MAV_2194|M.avium_104 -------------------------------MIALLAPGQGSQTEGMLSP Mb2971c|M.bovis_AF2122/97 ASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQGAQRIGMGRE Rv2946c|M.tuberculosis_H37Rv ASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQGAQRIGMGRE MMAR_1762|M.marinum_M ADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFPGQGSQRIGMARE MUL_2005|M.ulcerans_Agy99 ADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFPGQGSQRIGMARE MSMEG_6629|M.smegmatis_MC2_155 -----------------------------MNRPAFLYPGQGSQRAGMIAA TH_4621|M.thermoresistible__bu IADGVEALTAGLREVADGDAPYQPAVGMDDKAPVWVFSGQGSQWAGMGAE . : .***:* ** Mflv_2779|M.gilvum_PYR-GCK WL-ELPGAAERIASWSEISG----LDLARLGTTATAEEITDTAVTQPLVV Mvan_3754|M.vanbaalenii_PYR-1 WL-ELPGAAQRIQAWSEISG----LDLAALGTTASAEEITDTAVTQPLVV MAB_1879c|M.abscessus_ATCC_199 WL-ELPGATDQVEQWSKASG----LDLVRLGTTATAEEITDTSITQPLVV MLBr_01653|M.leprae_Br4923 WL-GLPGAADQIATWSKASG----LDLVRLGTTASTEEITDTAVAQPLIV MAV_2194|M.avium_104 WL-ELDGAADQLALWSKASG----LDLVRLGTTASTEEITDTAVTQPLVV Mb2971c|M.bovis_AF2122/97 LYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADLLDSTEFAQPALF Rv2946c|M.tuberculosis_H37Rv LYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADLLDSTEFAQPALF MMAR_1762|M.marinum_M LHDQLPVFAEAFDAVADELDRHLRIPLREVMWGSDAALLDSTEFAQPALF MUL_2005|M.ulcerans_Agy99 LHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGSDVALLDSTEFAQAALF MSMEG_6629|M.smegmatis_MC2_155 LP-PTSATRRVLDEASDALG--------GLGYLDTADGLASTRNAQLALL TH_4621|M.thermoresistible__bu LLATEQVFAAKIAEIEPLVARE--SGFSVTEAMTASETVTGIDRVQPTLF . : . .* :. Mflv_2779|M.gilvum_PYR-GCK AATLLAYEELNKRDVLTGDE---KIIAAGHSVGEIAAYAIAGVISADDAV Mvan_3754|M.vanbaalenii_PYR-1 AATLLAYEELTKRDVLGGIEGPVDIVAAGHSVGEIAAYAIAGVISADEAV MAB_1879c|M.abscessus_ATCC_199 ALTLLAYDELNKRGHLNGKIASGEVIVAGHSVGEIAAYAIAGVISADEAI MLBr_01653|M.leprae_Br4923 ATTLLAHQELAKHALFENALD--NLIVAGHSVGEIAAYSIAGVIAADDAV MAV_2194|M.avium_104 AATLLAHQELTRRGLLADA----DLVVAGHSVGEIAAYAIAGVMAADDAV Mb2971c|M.bovis_AF2122/97 AVEVASFAVLRDWGVLPDF-------VMGHSVGELAAAHAAGVLTLADAA Rv2946c|M.tuberculosis_H37Rv AVEVASFAVLRDWGVLPDF-------VMGHSVGELAAAHAAGVLTLADAA MMAR_1762|M.marinum_M AVEVALFAALQRWGLQPDF-------VMGHSVGELSAAYVAGVLTLADAA MUL_2005|M.ulcerans_Agy99 AVEVALFAALQRWGLQPDF-------VMGHSVGELSAAYVAGVLTLVDAA MSMEG_6629|M.smegmatis_MC2_155 ICGVAATRTLDEVYGVRPG------VTAGHSAGAFAAAVAAGVLTFHEAL TH_4621|M.thermoresistible__bu AIQVALAATMQSYGVRPGA-------VIGHSLGEVAAAVVAGALSLEDGV : : . *** * .:* **.:: :. Mflv_2779|M.gilvum_PYR-GCK SLAATRGKEMAKACALEPTGMSALLGGDE--AEVLARLEALDLVPANRNA Mvan_3754|M.vanbaalenii_PYR-1 SLAATRGKEMAKACALEPTGMSALLGGDE--AEVLARLEALDLIPANRNA MAB_1879c|M.abscessus_ATCC_199 TLAATRGAEMAKACALDPTGMSAVLGGDE--AEVLERLEALELVPANRNA MLBr_01653|M.leprae_Br4923 ALAATRGAEMAKACAIEPTGMSAVLGGDE--ADVLNRLEELDLVPANRNA MAV_2194|M.avium_104 ALAATRGAEMAKACAVEPTGMSAVLGGDE--AEVLARLEQLDLFPANRNA Mb2971c|M.bovis_AF2122/97 MLVVARGRLMQ---ALPAGGAMVAVAASE--DEVEPLLGEGVGIAAIN-A Rv2946c|M.tuberculosis_H37Rv MLVVARGRLMQ---ALPAGGAMVAVAASE--DEVEPLLGEGVGIAAIN-A MMAR_1762|M.marinum_M MLVVARGRLMQ---ALPAGGAMVAVAAAE--DEVLPSLTDGVGIAAIN-A MUL_2005|M.ulcerans_Agy99 MLVVARGRLMQ---ALPAGGAMVAVAAAE--DEVLPSLTDGVGIAAIN-A MSMEG_6629|M.smegmatis_MC2_155 DAVGVRAAAMEAACAPGEWGMAAVTGMGQRAAGALVAEARATVWIANINA TH_4621|M.thermoresistible__bu KVICRRSRLCLR--LAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIAS *. . . : : : Mflv_2779|M.gilvum_PYR-GCK AGQIVAAGAVAALEKLAEDPP-ARAR-VRPLATAGAFHTRYMAPALDEYT Mvan_3754|M.vanbaalenii_PYR-1 AGQIVAAGAVSALEKLAEDPP-SRAR-VRPLATAGAFHTRYMAPALDGYA MAB_1879c|M.abscessus_ATCC_199 VGQIVAAGRITALEKLAEDPP-AKAR-VRQLATAGAFHTHFMAPAQEAYA MLBr_01653|M.leprae_Br4923 AGQIVAAGRLTALEKLAEDPP-ARAR-VRALDVAGAFHTEFMTAALDGFA MAV_2194|M.avium_104 AGQIVAAGSLAALEKLAEDPP-AKAR-VRALGVAGAFHTKYMASALDGYA Mb2971c|M.bovis_AF2122/97 PESVVISGAQAAANAIADRFA-AQGRRVHQLAVSHAFHSPLMEPMLEEFA Rv2946c|M.tuberculosis_H37Rv PESVVISGAQAAANAIADRFA-AQGRRVHQLAVSHAFHSPLMEPMLEEFA MMAR_1762|M.marinum_M PKSVVISGAEAAVTAISDQFA-QQGRRVHRLAVSHAFHSPLMEPMLEEFA MUL_2005|M.ulcerans_Agy99 PKSVVISGAEAAVTAISDQFA-QQGRRVHRLAVSHAFHSPLMEPMLEEFA MSMEG_6629|M.smegmatis_MC2_155 ADQVVLGGTVDGLRDARAAARRMGARRFEMLDVAVASHGPVQARTATVIA TH_4621|M.thermoresistible__bu PESTVIGGATDTVRELVAAWE-AQGVMAREVAVDVASHSPQVDPILDELE . * .* . . : . * * Mflv_2779|M.gilvum_PYR-GCK RVADRIDPQEPAVTLLSNSDGRPVSGG--ADALAKLVAQMTRPVRWDLCT Mvan_3754|M.vanbaalenii_PYR-1 TVADRIDPAEPTVTLLSNSDGRPVSSA--ADAMAKLVAQMTRPVRWDLCT MAB_1879c|M.abscessus_ATCC_199 AAAAAITPSEPTVTLLSNLDGSPVTSG--ADAMAKLVNQMTSPVRWDLCT MLBr_01653|M.leprae_Br4923 EAAASITIAEPIAMLLSNRDGKPVASA--ATGMETLISQLTHPARWDLCN MAV_2194|M.avium_104 AAAAAVQTAEPTATLLSNRDGKPVASA--AAAMEALVAQLTQPVRWDLCT Mb2971c|M.bovis_AF2122/97 RVAARVQAREPQLGLVSNVTGELAGPD--FGSAQYWVDHVRRPVRFADSA Rv2946c|M.tuberculosis_H37Rv RVAARVQAREPQLGLVSNVTGELAGPD--FGSAQYWVDHVRRPVRFADSA MMAR_1762|M.marinum_M RIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAVRFADSA MUL_2005|M.ulcerans_Agy99 RIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAVRFADSA MSMEG_6629|M.smegmatis_MC2_155 ERLAAVPRRHQSAAYLTNVGARRIVDD-ADAVLRDLAESVAKPVQWYDIA TH_4621|M.thermoresistible__bu EILADLQPMTPTVPYYSATSYDPREKP--VCDADYWVDNLRHEVRFAAAV : : : .:: Mflv_2779|M.gilvum_PYR-GCK AAMKDLG----VTALVEFPPAGTLTGIAKRELRGTPTHAVKSP-ADLDG- Mvan_3754|M.vanbaalenii_PYR-1 ASMKDLG----VTAIVEFPPAGTLTGIAKRELRGVPTHAVKSP-ADLDG- MAB_1879c|M.abscessus_ATCC_199 EYFKTANDTPAATAVVELPPSGALSGIAKREMRGVPNHALKTP-EDLEA- MLBr_01653|M.leprae_Br4923 VTLREHN----VTAIVELPPAGALTGIAKRELREVTTCAVKSP-TDLDK- MAV_2194|M.avium_104 ATLRELE----VAAAVEFPPAGTLTGIAKRELRGVSARAVKSP-ADLDA- Mb2971c|M.bovis_AF2122/97 RHLQTLG----ATHFIEAGPGSGLTGSIEQSLAPAEAMVVSMLGKDRPE- Rv2946c|M.tuberculosis_H37Rv RHLQTLG----ATHFIEAGPGSGLTGSIEQSLAPAEAMVVSMLGKDRPE- MMAR_1762|M.marinum_M RQLHTLG----VTHFVEVGPGSGLTGSIEQSLAPAEAVVVSMLGKDRPE- MUL_2005|M.ulcerans_Agy99 RQLHTLG----VTHFVEVGPGSGLTGSIEQSLAPAEAVVVSMLGKDRPE- MSMEG_6629|M.smegmatis_MC2_155 QVLPELG----VQRTVEMPPGHVLT----SLLAAVPVTATSVDDVGYAA- TH_4621|M.thermoresistible__bu QAALEDG----FRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQE * * *: . Mflv_2779|M.gilvum_PYR-GCK -LRGAW-------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -LAASFRA------------------------------------------ MAB_1879c|M.abscessus_ATCC_199 -LAEL--------------------------------------------- MLBr_01653|M.leprae_Br4923 -LANL--------------------------------------------- MAV_2194|M.avium_104 -LAEL--------------------------------------------- Mb2971c|M.bovis_AF2122/97 -LASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWETPG Rv2946c|M.tuberculosis_H37Rv -LASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWETPG MMAR_1762|M.marinum_M -VASVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEVPG MUL_2005|M.ulcerans_Agy99 -VASVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEVPG MSMEG_6629|M.smegmatis_MC2_155 -ISA---------------------------------------------- TH_4621|M.thermoresistible__bu MPHGVRTMVGDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENG Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 ADGPADAAGLGLGATEHALLGAVVERPDSDEVVLTGRLSLADQPWLADHV Rv2946c|M.tuberculosis_H37Rv ADGPADAAGLGLGATEHALLGAVVERPDSDEVVLTGRLSLADQPWLADHV MMAR_1762|M.marinum_M ADGPADATGLGLGGAEHALLGAVVERPDSGGVVLTGRLALADQPWLADHV MUL_2005|M.ulcerans_Agy99 ADGPADATGLGLGGAEHALLGAVVERPDSGGVVLTGRLALADQPWLADHV MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu EQ---QTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQ Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 VNGVVLFPGAGFVELVIRAGDEVG-CALIEELVLAAPLVMHPGVGVQVQV Rv2946c|M.tuberculosis_H37Rv VNGVVLFPGAGFVELVIRAGDEVG-CALIEELVLAAPLVMHPGVGVQVQV MMAR_1762|M.marinum_M IGGVVLFPGAGFVELAIRAGDEVG-CAVVEELVLAAPLVLHPGMGVQVQV MUL_2005|M.ulcerans_Agy99 IGGVVLFPGAGFVELAIRAGDEVG-CAVVEELVLAAPLVLHPGMGVQVQV MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu IHTVAALPGAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSA Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 VVGAADESGHRAVSVYSRGDQSQGWLLNAEGMLGVAAAETPMDLSVWPPE Rv2946c|M.tuberculosis_H37Rv VVGAADESGHRAVSVYSRGDQSQGWLLNAEGMLGVAAAETPMDLSVWPPE MMAR_1762|M.marinum_M IVGAADDSGNRALSVYSRGDQSEDWLLNAEGMLGVEAASSGADLSVWPPE MUL_2005|M.ulcerans_Agy99 IVGTADDSGNRALSVYSRGDKSEDWLLNAEGMLGVEAASSGADLSVWPPE MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu VASAVEPGTLEFAVETAKDGEHERRATAVLGAADDTEPPQAHDIDALLAE Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 GAESVDISDGYAQLAERGYAYGPAFQGLVAIWRRG---SELFAEVVAPGE Rv2946c|M.tuberculosis_H37Rv GAESVDISDGYAQLAERGYAYGPAFQGLVAIWRRG---SELFAEVVAPGE MMAR_1762|M.marinum_M GAESVDISDGYAQLADRGYAYGPGFQGLVGVWRRD---SELFAEVVAP-- MUL_2005|M.ulcerans_Agy99 GAESVDISDGYAQLADRGYAYGPGFQGLVGVWRRD---SELFAEVVAP-- MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu HPTRIEGDELRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQ Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 AGVAVDRMGMHPAVLDAVLHALGLAVEKTQASTETRLPFCWRGVSLHAGG Rv2946c|M.tuberculosis_H37Rv AGVAVDRMGMHPAVLDAVLHALGLAVEKTQASTETRLPFCWRGVSLHAGG MMAR_1762|M.marinum_M SGVAVDKMGMHPVVLDAVLHALGLTAEQNPDSDETKLPFCWRGVSLHAGG MUL_2005|M.ulcerans_Agy99 SGVAVDKMGMHPVVLDAVLHALGLTAEQNPDSDETKLPFCWRGVSLHAGG MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu IRSQQAPYGIHPALLDACFQSVAAHPDVQGAGSGLLLPLGVRRLQAFGPT Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 AGR----VRARFASAGADAISVDVCDATGLPVLTVR-------------- Rv2946c|M.tuberculosis_H37Rv AGR----VRARFASAGADAISVDVCDATGLPVLTVR-------------- MMAR_1762|M.marinum_M AGR----VRARLTMSGPDSISVEIADAAGLPVLTVG-------------- MUL_2005|M.ulcerans_Agy99 AGR----VRARLTMSGPDSISVEIADAAGLPVLTVG-------------- MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu RGARYCYARVTDADGSKAEADLDVLDEHGNVLLRVQGLLMGGAAADGDDR Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 ------SLVTRPITAEQLRAAVTAAGG-ASDQGPLEVVWSPISVVSGGAN Rv2946c|M.tuberculosis_H37Rv ------SLVTRPITAEQLRAAVTAAGG-ASDQGPLEVVWSPISVVSGGAN MMAR_1762|M.marinum_M ------ALVTRAMSAAQLRAAVAAAGGGAPDQGPLDVIWSPIPLSGSGTN MUL_2005|M.ulcerans_Agy99 ------ALVTRAMSAAQLRAAVAEAGGGAPDQGPLDVIWSPIPLSGSGTN MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu DRVLGERLLTIEWQRRDLPEADSAAGKWLLVSTSATADVSATRLSDALKQ Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 GSAPPAPVSWADFCAGSDG----DASVVVWELESAGGQASSVVGSVYAAT Rv2946c|M.tuberculosis_H37Rv GSAPPAPVSWADFCAGSDG----DASVVVWELESAGGQASSVVGSVYAAT MMAR_1762|M.marinum_M GSAQPAVVSWADFCAGGDGGAAGDAGVVVWEPNPAG---EDVVGSVYAAT MUL_2005|M.ulcerans_Agy99 GSAQPAVVSWADFCAGGDGGAAGDAGVVVWEPNPAG---EDVVGPVYAAT MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu AGAESTSMCWPQQADHADNVDRFRAGIADGVTGVVVLTGPKNGNPDDAAA Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 HTALEVLQSWL--------GADRAATLVVLTHGGVGLAGEDISDLAAAAV Rv2946c|M.tuberculosis_H37Rv HTALEVLQSWL--------GADRAATLVVLTHGGVGLAGEDISDLAAAAV MMAR_1762|M.marinum_M HAALEVLQSWF--------DGDRAGTLVVLTHGAVAMPGENVSDLAGAAV MUL_2005|M.ulcerans_Agy99 HAALEVLQSWF--------DGDRAGTLVVLTHGAVAMPGENVSDLAGAAV MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu RRGSDYVRHLVRITRELAEIDGDAPRLFVVTRGAQAVLPQDRPNLEQAGL Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 WGMARSAQAENPGRIVLIDTDAAVDASVLAGVGEPQLLVRGGTVHAPRLS Rv2946c|M.tuberculosis_H37Rv WGMARSAQAENPGRIVLIDTDAAVDASVLAGVGEPQLLVRGGTVHAPRLS MMAR_1762|M.marinum_M WGIVRSAQAENPGRIVLVDADAAVEAAELVAVGEPQLVVRSGAAHAARLA MUL_2005|M.ulcerans_Agy99 WGIVRSAQAENPGRIVLVDADAAVEAAELVAVGEPQLVVRSGAAHAARLA MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu RGLLRVIGAEHPHLRTTQIDIADDADLDRVAVQLLGGGAEDETAWRDGQW Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 PAPALLALPAAESAWRLAAGGGGTLEDLVIQPCP----------EVQAPL Rv2946c|M.tuberculosis_H37Rv PAPALLALPAAESAWRLAAGGGGTLEDLVIQPCP----------EVQAPL MMAR_1762|M.marinum_M PAAPLLAVPADESAWRLAAGGGGTLEDLVIEPCP----------EVQAPL MUL_2005|M.ulcerans_Agy99 PAAPLLAVPADESAWRLAAGGGGTLEDLVIEPCP----------EVQAPL MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu YTARLSLSPLRPEERKQAVVDCERDGMRLEIRTPGDLETMELAAFDRVPP Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 QAGQVRVAVAAVGVNFRDVVAALGMYP---GQAPPLGAEGAGVVLETGPE Rv2946c|M.tuberculosis_H37Rv QAGQVRVAVAAVGVNFRDVVAALGMYP---GQAPPLGAEGAGVVLETGPE MMAR_1762|M.marinum_M AAGQVRVAVRAVGVNFRDVVAALGMYP---GEAPPLGAEGAGVVLEVGPQ MUL_2005|M.ulcerans_Agy99 AAGQVRVAVRAVGVNFRDVVAALGMYP---GAAPPLGAEGAGVVLEVGPQ MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu GPGQIEVAVTASSINFADVLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPD Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 VTDLAVGDAVMGFLGG--AGPLAVVDQQLVTRVPQGWSFAQAAAVPVVFL Rv2946c|M.tuberculosis_H37Rv VTDLAVGDAVMGFLGG--AGPLAVVDQQLVTRVPQGWSFAQAAAVPVVFL MMAR_1762|M.marinum_M VSGVAVGDSVMGFLGG--AGPLSVVDQQLITRMPQGWSFAQAAAVPVVFL MUL_2005|M.ulcerans_Agy99 VSGVAVGDSVMGFLGG--AGPLSVVDQQLITRMPQGWSFAQAAAVPVVFL MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu VTSHRVGDRVGGLSPNGCWSTFVTCDADLAVPLPDGLTEGQAAAVSTAHA Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 TAWYGLADLAEIKAGESVLIHAGTGGVGMAAVQLARQWGVEVFVTASRGK Rv2946c|M.tuberculosis_H37Rv TAWYGLADLAEIKAGESVLIHAGTGGVGMAAVQLARQWGVEVFVTASRGK MMAR_1762|M.marinum_M TALFGLQDLAKIQPGESVLIHAGTGGVGMAAVQLARHWGVEIFVTASRGK MUL_2005|M.ulcerans_Agy99 TALFGLQDLAKIQPGESVLIHAGTGGVGMAAVQLARHWGVEIFVTASRGK MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu TAWYGLHDLARLGAGEKVLIHSATGGVGLAAIAIARSVGAQIYATAGSPA Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 WDTLRAMGFDDDHIGDSRTCEFEEKFLAVTEGRGVDVVLDSLAGEFVDAS Rv2946c|M.tuberculosis_H37Rv WDTLRAMGFDDDHIGDSRTCEFEEKFLAVTEGRGVDVVLDSLAGEFVDAS MMAR_1762|M.marinum_M WDTLRAMGFDDDHIGDSRTLDFEEKFLAVTDGRGVDVVLDSLAGDFVDAS MUL_2005|M.ulcerans_Agy99 WDTLRAMGFDDDHIGDSRTLDFEEKFLAVTDGRGVDVVLDSLAGDFVDAS MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu RRDLLR-DMGIEHVYDSRSTAFADEIRRDTDGYGVDVVLNSLPGAAQRAG Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 LRLLVRGGRFLEMGKTDIR-----DAQEIAANYPGVQYRAFDLSEAGPAR Rv2946c|M.tuberculosis_H37Rv LRLLVRGGRFLEMGKTDIR-----DAQEIAANYPGVQYRAFDLSEAGPAR MMAR_1762|M.marinum_M LRLLVRGGRFLEMGKTDIR-----DADKIAANYPGVWYRAFDLSEAGPVR MUL_2005|M.ulcerans_Agy99 LRLLVRGGRFLEMGKTDIR-----DADKIAANYPGVWYRAFDLSEAGPVR MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu LELLSFGGRFIEIGKRDIYGDTRLGLFPFRRNLAFHGVDLGLMADSHPHK Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 MQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTM Rv2946c|M.tuberculosis_H37Rv MQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTM MMAR_1762|M.marinum_M MQEMLAEVRELFDTAVLHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTM MUL_2005|M.ulcerans_Agy99 MQEMLAEVRELFDTAVLHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTM MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu IRELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDV Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 PSALADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAE Rv2946c|M.tuberculosis_H37Rv PSALADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAE MMAR_1762|M.marinum_M PSALADGLADATVLITGATGAVGAVLARHMLDAYGVRHLVLASRRGDRAE MUL_2005|M.ulcerans_Agy99 PSALADGLADATVLITGATGAVGAVLARHMLDGYGVRHLVLASRRGDRAE MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu PHTG----RADVVVPPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAAAGA Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 GAAELAADLTEAGAKGQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAA Rv2946c|M.tuberculosis_H37Rv GAAELAADLTEAGAKVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAA MMAR_1762|M.marinum_M GAAELAAELSEAGANVQVVACDVADRDAVEAMLARLSGEYPPVRGVIHAA MUL_2005|M.ulcerans_Agy99 GAAELAAELSEAGANVQVVACDVADRDAVEAMLARLSGEYPPVRGVIHAA MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu GCIVLNGRSAPSGEALRTIEQLRAAGTEVIVECGXXX-RGQPVEVAVPTE Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 GVLDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSMFVLCSSIAA Rv2946c|M.tuberculosis_H37Rv GVLDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSMFALCSSIAA MMAR_1762|M.marinum_M GVLDDAVISSLTPERIDTVLRAKVDAAWNLHEATLDLDLSMFVLCSSIAA MUL_2005|M.ulcerans_Agy99 GVLDDAVISSLTPERIDTVLRAKVDAAWNLHEATLDLDLSMFVLCSSIAA MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu LRHADEHPDRRGAQLCDEFARGEQGAQRNQHRTDAGEGQ----RDAHPPG Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 TVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISLAWGLWEQPGGMTAHLS Rv2946c|M.tuberculosis_H37Rv TVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISLAWGLWEQPGGMTAHLS MMAR_1762|M.marinum_M TVGSPGQGNYSAANSFLDGLAAHRQAAGLAGISVAWGLWEQSGGMAAHLS MUL_2005|M.ulcerans_Agy99 TVGSPGQGNYSAANSFLDGLAAHRQAAGLAGISVAWGLWEQSGGMAAHLS MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu AVGHDQPDPGALSDTGLDERGGQFPGVGVQIPVADPGVGIDHRGAVRVDS Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 SRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAALDARAQ Rv2946c|M.tuberculosis_H37Rv SRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAALDARAQ MMAR_1762|M.marinum_M SRDLARMSRSGLAPMNPEQAVGLLDAVLAINHPLMVATLLDRPALEARAQ MUL_2005|M.ulcerans_Agy99 SRDLARMSRSGLAPMNPEQAVGLLDAVLAINHPLMVATLLDRPALEARAQ MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu GVPAQQGVDGEVVRHRTLSSVRSGRSSRWTAPGSRCGSGRRYGGESCRRT Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 AGALPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLV Rv2946c|M.tuberculosis_H37Rv AGALPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLV MMAR_1762|M.marinum_M AGGLPPLFAGVVRRPRRRQIEDTGDAAQSKSALAERLNGLSAGERQDALV MUL_2005|M.ulcerans_Agy99 AGGLPPLFAGVVRRPRRRQIEDTGDAAQSKSALAERLNGLSAGERQDALV MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu TGPAAGAAARRGRTRRRRRPRRPPPPPDRVRHRAGPAHGPVRR------- Mflv_2779|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01653|M.leprae_Br4923 -------------------------------------------------- MAV_2194|M.avium_104 -------------------------------------------------- Mb2971c|M.bovis_AF2122/97 GLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTL Rv2946c|M.tuberculosis_H37Rv GLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTL MMAR_1762|M.marinum_M GLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNRLKSATGLTL MUL_2005|M.ulcerans_Agy99 GLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNRFKSATGLTL MSMEG_6629|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_2779|M.gilvum_PYR-GCK ------------------------------------------------- Mvan_3754|M.vanbaalenii_PYR-1 ------------------------------------------------- MAB_1879c|M.abscessus_ATCC_199 ------------------------------------------------- MLBr_01653|M.leprae_Br4923 ------------------------------------------------- MAV_2194|M.avium_104 ------------------------------------------------- Mb2971c|M.bovis_AF2122/97 PPTVIFDHPTPTAVAEYVAQQMSGSRPTESGDPTSQVVEPAAAEVSVHA Rv2946c|M.tuberculosis_H37Rv PPTVIFDHPTPTAVAEYVAQQMSGSRPTESGDPTSQVVEPAAAEVSVHA MMAR_1762|M.marinum_M PPTVIFDHPTPTAIAEYVGRQIPDSQATQAEE--EKLPESDGEMVSVTA MUL_2005|M.ulcerans_Agy99 PPTVIFDHPTPTAIAEYVGRQIPDSQATQAEE--EKLPESDGEMVSVTA MSMEG_6629|M.smegmatis_MC2_155 ------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------