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M. smegmatis MC2 155 MSMEG_6629 (mdcH)

annotation: malonate decarboxylase, epsilon subunit
coordinates: 6681119 - 6682018
length: 299

NRPAFLYPGQGSQRAGMIAALPPTSATRRVLDEASDALGGLGYLDTADGLASTRNAQLALLICGVAATRT
LDEVYGVRPGVTAGHSAGAFAAAVAAGVLTFHEALDAVGVRAAAMEAACAPGEWGMAAVTGMGQRAAGAL
VAEARATVWIANINAADQVVLGGTVDGLRDARAAARRMGARRFEMLDVAVASHGPVQARTATVIAERLAA
VPRRHQSAAYLTNVGARRIVDDADAVLRDLAESVAKPVQWYDIAQVLPELGVQRTVEMPPGHVLTSLLAA
VPVTATSVDDVGYAAISA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6629mdcH-100% (299)malonate decarboxylase, epsilon subunit
M. smegmatis MC2 155MSMEG_4325-1e-1330.20% (245) malonyl CoA-acyl carrier protein transacylase
M. smegmatis MC2 155MSMEG_4512-8e-1231.31% (198) polyketide synthetase mbtd

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2971cpks15e-1932.35% (306) polyketide synthase PKS1
M. gilvum PYR-GCKMflv_2779-9e-2031.32% (281) (acyl-carrier protein) S-malonyltransferase
M. tuberculosis H37RvRv2946cpks15e-1932.35% (306) polyketide synthase PKS1
M. leprae Br4923MLBr_01653fabD9e-1729.08% (282) malonyl CoA-
M. abscessus ATCC 19977MAB_1879c-1e-1629.31% (290) putative malonyl CoA-ACP transacylase FabD
M. marinum MMMAR_1762pks15/12e-1831.49% (308) polyketide synthase Pks15/1
M. avium 104MAV_2194-3e-1930.36% (280) malonyl CoA-acyl carrier protein transacylase
M. thermoresistible (build 8)TH_4621-6e-1427.95% (297) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2005pks15/12e-1831.49% (308) polyketide synthase Pks15/1
M. vanbaalenii PYR-1Mvan_3754-4e-2031.76% (296) (acyl-carrier protein) S-malonyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           MIEEQRTMSVEGADQQSEKLFHYLKKVAVELDETRARLREYEQRATEPVA
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               -----MTTSGESADQQNDKLFRYLKKVAVELDEARARLREYEQRATEPVA
MUL_2005|M.ulcerans_Agy99           -----MTTSGESADQQNDKLFRYLKKVAVELDEARARLREYEQRATEPVA
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      -------------------------------------VNIVGDTPVNAVA
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VVGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDA
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               VVGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDA
MUL_2005|M.ulcerans_Agy99           VVGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDA
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      VIGMACRLPGGIDSPQRLWEALLRGDDMVTEIPVDR-WDADDYFDPEPGV
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           EGKTYTRWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEH
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               EGKTYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEH
MUL_2005|M.ulcerans_Agy99           EGKTYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEH
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      PGRTVSRWGAFLDDVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEH
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           AGIDPLSLRGSATGVYTGIFAASYGNRDTGG---LQGYGLTGTSISVASG
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               AGIDPMSLRGSSTGVFTGIFAPSYGGKDVGA---LQGYGLTGSPVSVASG
MUL_2005|M.ulcerans_Agy99           AGIDPMSLRGSSTGVFTGIFAPSYGGKDVGA---LQGYGLTGSPVSVASG
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      AGLTPADVEGSSTGVFVGLSHDDYALLTSDAGALEEAYGFTGSAFSMASG
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           RVSYVLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMG
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               RVAYVLGLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMG
MUL_2005|M.ulcerans_Agy99           RVAYVLGLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMG
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      RIAYRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVML
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRL
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRN
MUL_2005|M.ulcerans_Agy99           LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRN
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      EPRKYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRD
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGLSAADVDV
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               GHNVLAVVRGSAINQDGASNGLTAPNGLAQQRVIQAALANCGLTSADVDV
MUL_2005|M.ulcerans_Agy99           GHNVLAVVRGSAINQDGASNGLTAPNGLTQQRVIQAALANCGLTSADVDV
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      NDRILAVVRGTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGM
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VEAHGTATTLGDPIEAQALLSTYGQGRPAEQPLWVGSIKSNMGHTQAAAG
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               VEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAG
MUL_2005|M.ulcerans_Agy99           VEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAG
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      VEAHGTGTPVGDPIEYNSLTQVYGKTGP----CALTSVKTNFGHAESAAG
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VAGVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREWSV-DG
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               VAGVIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AG
MUL_2005|M.ulcerans_Agy99           VAGVIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AG
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      ALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREG
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           RPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVEASESTGGPRPSMVPW
Rv2946c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1762|M.marinum_M               RPRRAGVSSFGISGTNAHVILEEAPAP---EAVPDSESNKGEPSLPVVPW
MUL_2005|M.ulcerans_Agy99           RPRRAGVSSFGISGTNAHVILEEAPAP---EAVPDSESNKGEPSLPVVPW
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      CPRRAAVSSYGMSGTNVHAVLEQAPEPVQRPEESADTDAAG-----PLVF
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSLASRSVFEHRAVVVG
Rv2946c|M.tuberculosis_H37Rv        MISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSLASRSVFEHRAVVVG
MMAR_1762|M.marinum_M               VISARSAEALTAQAGRLLAHVQADPQSNPVDIGFSLAGRSAFEHRAVVVG
MUL_2005|M.ulcerans_Agy99           VISARSAEALTAQAGRLLAHVQADPQSNPVDIGFSLAGRSAFEHRAVVVG
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      ALSSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTV
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------MPQTTVLAFLAPGQGSQTPGMLTE
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------MPQTTVLAFLAPGQGSQTPGMLAE
MAB_1879c|M.abscessus_ATCC_199      -------------------------------MIALLAPGQGSQTPGMLTP
MLBr_01653|M.leprae_Br4923          -------------------------------MIALLAPGQGSQTEGMLSP
MAV_2194|M.avium_104                -------------------------------MIALLAPGQGSQTEGMLSP
Mb2971c|M.bovis_AF2122/97           ASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQGAQRIGMGRE
Rv2946c|M.tuberculosis_H37Rv        ASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQGAQRIGMGRE
MMAR_1762|M.marinum_M               ADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFPGQGSQRIGMARE
MUL_2005|M.ulcerans_Agy99           ADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFPGQGSQRIGMARE
MSMEG_6629|M.smegmatis_MC2_155      -----------------------------MNRPAFLYPGQGSQRAGMIAA
TH_4621|M.thermoresistible__bu      IADGVEALTAGLREVADGDAPYQPAVGMDDKAPVWVFSGQGSQWAGMGAE
                                                                     . : .***:*  **   

Mflv_2779|M.gilvum_PYR-GCK          WL-ELPGAAERIASWSEISG----LDLARLGTTATAEEITDTAVTQPLVV
Mvan_3754|M.vanbaalenii_PYR-1       WL-ELPGAAQRIQAWSEISG----LDLAALGTTASAEEITDTAVTQPLVV
MAB_1879c|M.abscessus_ATCC_199      WL-ELPGATDQVEQWSKASG----LDLVRLGTTATAEEITDTSITQPLVV
MLBr_01653|M.leprae_Br4923          WL-GLPGAADQIATWSKASG----LDLVRLGTTASTEEITDTAVAQPLIV
MAV_2194|M.avium_104                WL-ELDGAADQLALWSKASG----LDLVRLGTTASTEEITDTAVTQPLVV
Mb2971c|M.bovis_AF2122/97           LYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADLLDSTEFAQPALF
Rv2946c|M.tuberculosis_H37Rv        LYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADLLDSTEFAQPALF
MMAR_1762|M.marinum_M               LHDQLPVFAEAFDAVADELDRHLRIPLREVMWGSDAALLDSTEFAQPALF
MUL_2005|M.ulcerans_Agy99           LHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGSDVALLDSTEFAQAALF
MSMEG_6629|M.smegmatis_MC2_155      LP-PTSATRRVLDEASDALG--------GLGYLDTADGLASTRNAQLALL
TH_4621|M.thermoresistible__bu      LLATEQVFAAKIAEIEPLVARE--SGFSVTEAMTASETVTGIDRVQPTLF
                                               .                          : .   .*  :.

Mflv_2779|M.gilvum_PYR-GCK          AATLLAYEELNKRDVLTGDE---KIIAAGHSVGEIAAYAIAGVISADDAV
Mvan_3754|M.vanbaalenii_PYR-1       AATLLAYEELTKRDVLGGIEGPVDIVAAGHSVGEIAAYAIAGVISADEAV
MAB_1879c|M.abscessus_ATCC_199      ALTLLAYDELNKRGHLNGKIASGEVIVAGHSVGEIAAYAIAGVISADEAI
MLBr_01653|M.leprae_Br4923          ATTLLAHQELAKHALFENALD--NLIVAGHSVGEIAAYSIAGVIAADDAV
MAV_2194|M.avium_104                AATLLAHQELTRRGLLADA----DLVVAGHSVGEIAAYAIAGVMAADDAV
Mb2971c|M.bovis_AF2122/97           AVEVASFAVLRDWGVLPDF-------VMGHSVGELAAAHAAGVLTLADAA
Rv2946c|M.tuberculosis_H37Rv        AVEVASFAVLRDWGVLPDF-------VMGHSVGELAAAHAAGVLTLADAA
MMAR_1762|M.marinum_M               AVEVALFAALQRWGLQPDF-------VMGHSVGELSAAYVAGVLTLADAA
MUL_2005|M.ulcerans_Agy99           AVEVALFAALQRWGLQPDF-------VMGHSVGELSAAYVAGVLTLVDAA
MSMEG_6629|M.smegmatis_MC2_155      ICGVAATRTLDEVYGVRPG------VTAGHSAGAFAAAVAAGVLTFHEAL
TH_4621|M.thermoresistible__bu      AIQVALAATMQSYGVRPGA-------VIGHSLGEVAAAVVAGALSLEDGV
                                       :     :                . *** * .:*   **.::  :. 

Mflv_2779|M.gilvum_PYR-GCK          SLAATRGKEMAKACALEPTGMSALLGGDE--AEVLARLEALDLVPANRNA
Mvan_3754|M.vanbaalenii_PYR-1       SLAATRGKEMAKACALEPTGMSALLGGDE--AEVLARLEALDLIPANRNA
MAB_1879c|M.abscessus_ATCC_199      TLAATRGAEMAKACALDPTGMSAVLGGDE--AEVLERLEALELVPANRNA
MLBr_01653|M.leprae_Br4923          ALAATRGAEMAKACAIEPTGMSAVLGGDE--ADVLNRLEELDLVPANRNA
MAV_2194|M.avium_104                ALAATRGAEMAKACAVEPTGMSAVLGGDE--AEVLARLEQLDLFPANRNA
Mb2971c|M.bovis_AF2122/97           MLVVARGRLMQ---ALPAGGAMVAVAASE--DEVEPLLGEGVGIAAIN-A
Rv2946c|M.tuberculosis_H37Rv        MLVVARGRLMQ---ALPAGGAMVAVAASE--DEVEPLLGEGVGIAAIN-A
MMAR_1762|M.marinum_M               MLVVARGRLMQ---ALPAGGAMVAVAAAE--DEVLPSLTDGVGIAAIN-A
MUL_2005|M.ulcerans_Agy99           MLVVARGRLMQ---ALPAGGAMVAVAAAE--DEVLPSLTDGVGIAAIN-A
MSMEG_6629|M.smegmatis_MC2_155      DAVGVRAAAMEAACAPGEWGMAAVTGMGQRAAGALVAEARATVWIANINA
TH_4621|M.thermoresistible__bu      KVICRRSRLCLR--LAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIAS
                                         *.            .  .     :                :   :

Mflv_2779|M.gilvum_PYR-GCK          AGQIVAAGAVAALEKLAEDPP-ARAR-VRPLATAGAFHTRYMAPALDEYT
Mvan_3754|M.vanbaalenii_PYR-1       AGQIVAAGAVSALEKLAEDPP-SRAR-VRPLATAGAFHTRYMAPALDGYA
MAB_1879c|M.abscessus_ATCC_199      VGQIVAAGRITALEKLAEDPP-AKAR-VRQLATAGAFHTHFMAPAQEAYA
MLBr_01653|M.leprae_Br4923          AGQIVAAGRLTALEKLAEDPP-ARAR-VRALDVAGAFHTEFMTAALDGFA
MAV_2194|M.avium_104                AGQIVAAGSLAALEKLAEDPP-AKAR-VRALGVAGAFHTKYMASALDGYA
Mb2971c|M.bovis_AF2122/97           PESVVISGAQAAANAIADRFA-AQGRRVHQLAVSHAFHSPLMEPMLEEFA
Rv2946c|M.tuberculosis_H37Rv        PESVVISGAQAAANAIADRFA-AQGRRVHQLAVSHAFHSPLMEPMLEEFA
MMAR_1762|M.marinum_M               PKSVVISGAEAAVTAISDQFA-QQGRRVHRLAVSHAFHSPLMEPMLEEFA
MUL_2005|M.ulcerans_Agy99           PKSVVISGAEAAVTAISDQFA-QQGRRVHRLAVSHAFHSPLMEPMLEEFA
MSMEG_6629|M.smegmatis_MC2_155      ADQVVLGGTVDGLRDARAAARRMGARRFEMLDVAVASHGPVQARTATVIA
TH_4621|M.thermoresistible__bu      PESTVIGGATDTVRELVAAWE-AQGVMAREVAVDVASHSPQVDPILDELE
                                      . * .*                .   . : .  * *            

Mflv_2779|M.gilvum_PYR-GCK          RVADRIDPQEPAVTLLSNSDGRPVSGG--ADALAKLVAQMTRPVRWDLCT
Mvan_3754|M.vanbaalenii_PYR-1       TVADRIDPAEPTVTLLSNSDGRPVSSA--ADAMAKLVAQMTRPVRWDLCT
MAB_1879c|M.abscessus_ATCC_199      AAAAAITPSEPTVTLLSNLDGSPVTSG--ADAMAKLVNQMTSPVRWDLCT
MLBr_01653|M.leprae_Br4923          EAAASITIAEPIAMLLSNRDGKPVASA--ATGMETLISQLTHPARWDLCN
MAV_2194|M.avium_104                AAAAAVQTAEPTATLLSNRDGKPVASA--AAAMEALVAQLTQPVRWDLCT
Mb2971c|M.bovis_AF2122/97           RVAARVQAREPQLGLVSNVTGELAGPD--FGSAQYWVDHVRRPVRFADSA
Rv2946c|M.tuberculosis_H37Rv        RVAARVQAREPQLGLVSNVTGELAGPD--FGSAQYWVDHVRRPVRFADSA
MMAR_1762|M.marinum_M               RIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAVRFADSA
MUL_2005|M.ulcerans_Agy99           RIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAVRFADSA
MSMEG_6629|M.smegmatis_MC2_155      ERLAAVPRRHQSAAYLTNVGARRIVDD-ADAVLRDLAESVAKPVQWYDIA
TH_4621|M.thermoresistible__bu      EILADLQPMTPTVPYYSATSYDPREKP--VCDADYWVDNLRHEVRFAAAV
                                         :          :                      :   .::    

Mflv_2779|M.gilvum_PYR-GCK          AAMKDLG----VTALVEFPPAGTLTGIAKRELRGTPTHAVKSP-ADLDG-
Mvan_3754|M.vanbaalenii_PYR-1       ASMKDLG----VTAIVEFPPAGTLTGIAKRELRGVPTHAVKSP-ADLDG-
MAB_1879c|M.abscessus_ATCC_199      EYFKTANDTPAATAVVELPPSGALSGIAKREMRGVPNHALKTP-EDLEA-
MLBr_01653|M.leprae_Br4923          VTLREHN----VTAIVELPPAGALTGIAKRELREVTTCAVKSP-TDLDK-
MAV_2194|M.avium_104                ATLRELE----VAAAVEFPPAGTLTGIAKRELRGVSARAVKSP-ADLDA-
Mb2971c|M.bovis_AF2122/97           RHLQTLG----ATHFIEAGPGSGLTGSIEQSLAPAEAMVVSMLGKDRPE-
Rv2946c|M.tuberculosis_H37Rv        RHLQTLG----ATHFIEAGPGSGLTGSIEQSLAPAEAMVVSMLGKDRPE-
MMAR_1762|M.marinum_M               RQLHTLG----VTHFVEVGPGSGLTGSIEQSLAPAEAVVVSMLGKDRPE-
MUL_2005|M.ulcerans_Agy99           RQLHTLG----VTHFVEVGPGSGLTGSIEQSLAPAEAVVVSMLGKDRPE-
MSMEG_6629|M.smegmatis_MC2_155      QVLPELG----VQRTVEMPPGHVLT----SLLAAVPVTATSVDDVGYAA-
TH_4621|M.thermoresistible__bu      QAALEDG----FRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQE
                                                    *  *   *:             .           

Mflv_2779|M.gilvum_PYR-GCK          -LRGAW--------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       -LAASFRA------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      -LAEL---------------------------------------------
MLBr_01653|M.leprae_Br4923          -LANL---------------------------------------------
MAV_2194|M.avium_104                -LAEL---------------------------------------------
Mb2971c|M.bovis_AF2122/97           -LASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWETPG
Rv2946c|M.tuberculosis_H37Rv        -LASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWETPG
MMAR_1762|M.marinum_M               -VASVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEVPG
MUL_2005|M.ulcerans_Agy99           -VASVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEVPG
MSMEG_6629|M.smegmatis_MC2_155      -ISA----------------------------------------------
TH_4621|M.thermoresistible__bu      MPHGVRTMVGDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENG
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           ADGPADAAGLGLGATEHALLGAVVERPDSDEVVLTGRLSLADQPWLADHV
Rv2946c|M.tuberculosis_H37Rv        ADGPADAAGLGLGATEHALLGAVVERPDSDEVVLTGRLSLADQPWLADHV
MMAR_1762|M.marinum_M               ADGPADATGLGLGGAEHALLGAVVERPDSGGVVLTGRLALADQPWLADHV
MUL_2005|M.ulcerans_Agy99           ADGPADATGLGLGGAEHALLGAVVERPDSGGVVLTGRLALADQPWLADHV
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      EQ---QTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQ
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VNGVVLFPGAGFVELVIRAGDEVG-CALIEELVLAAPLVMHPGVGVQVQV
Rv2946c|M.tuberculosis_H37Rv        VNGVVLFPGAGFVELVIRAGDEVG-CALIEELVLAAPLVMHPGVGVQVQV
MMAR_1762|M.marinum_M               IGGVVLFPGAGFVELAIRAGDEVG-CAVVEELVLAAPLVLHPGMGVQVQV
MUL_2005|M.ulcerans_Agy99           IGGVVLFPGAGFVELAIRAGDEVG-CAVVEELVLAAPLVLHPGMGVQVQV
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      IHTVAALPGAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSA
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VVGAADESGHRAVSVYSRGDQSQGWLLNAEGMLGVAAAETPMDLSVWPPE
Rv2946c|M.tuberculosis_H37Rv        VVGAADESGHRAVSVYSRGDQSQGWLLNAEGMLGVAAAETPMDLSVWPPE
MMAR_1762|M.marinum_M               IVGAADDSGNRALSVYSRGDQSEDWLLNAEGMLGVEAASSGADLSVWPPE
MUL_2005|M.ulcerans_Agy99           IVGTADDSGNRALSVYSRGDKSEDWLLNAEGMLGVEAASSGADLSVWPPE
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      VASAVEPGTLEFAVETAKDGEHERRATAVLGAADDTEPPQAHDIDALLAE
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GAESVDISDGYAQLAERGYAYGPAFQGLVAIWRRG---SELFAEVVAPGE
Rv2946c|M.tuberculosis_H37Rv        GAESVDISDGYAQLAERGYAYGPAFQGLVAIWRRG---SELFAEVVAPGE
MMAR_1762|M.marinum_M               GAESVDISDGYAQLADRGYAYGPGFQGLVGVWRRD---SELFAEVVAP--
MUL_2005|M.ulcerans_Agy99           GAESVDISDGYAQLADRGYAYGPGFQGLVGVWRRD---SELFAEVVAP--
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      HPTRIEGDELRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQ
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           AGVAVDRMGMHPAVLDAVLHALGLAVEKTQASTETRLPFCWRGVSLHAGG
Rv2946c|M.tuberculosis_H37Rv        AGVAVDRMGMHPAVLDAVLHALGLAVEKTQASTETRLPFCWRGVSLHAGG
MMAR_1762|M.marinum_M               SGVAVDKMGMHPVVLDAVLHALGLTAEQNPDSDETKLPFCWRGVSLHAGG
MUL_2005|M.ulcerans_Agy99           SGVAVDKMGMHPVVLDAVLHALGLTAEQNPDSDETKLPFCWRGVSLHAGG
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      IRSQQAPYGIHPALLDACFQSVAAHPDVQGAGSGLLLPLGVRRLQAFGPT
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           AGR----VRARFASAGADAISVDVCDATGLPVLTVR--------------
Rv2946c|M.tuberculosis_H37Rv        AGR----VRARFASAGADAISVDVCDATGLPVLTVR--------------
MMAR_1762|M.marinum_M               AGR----VRARLTMSGPDSISVEIADAAGLPVLTVG--------------
MUL_2005|M.ulcerans_Agy99           AGR----VRARLTMSGPDSISVEIADAAGLPVLTVG--------------
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      RGARYCYARVTDADGSKAEADLDVLDEHGNVLLRVQGLLMGGAAADGDDR
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           ------SLVTRPITAEQLRAAVTAAGG-ASDQGPLEVVWSPISVVSGGAN
Rv2946c|M.tuberculosis_H37Rv        ------SLVTRPITAEQLRAAVTAAGG-ASDQGPLEVVWSPISVVSGGAN
MMAR_1762|M.marinum_M               ------ALVTRAMSAAQLRAAVAAAGGGAPDQGPLDVIWSPIPLSGSGTN
MUL_2005|M.ulcerans_Agy99           ------ALVTRAMSAAQLRAAVAEAGGGAPDQGPLDVIWSPIPLSGSGTN
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      DRVLGERLLTIEWQRRDLPEADSAAGKWLLVSTSATADVSATRLSDALKQ
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GSAPPAPVSWADFCAGSDG----DASVVVWELESAGGQASSVVGSVYAAT
Rv2946c|M.tuberculosis_H37Rv        GSAPPAPVSWADFCAGSDG----DASVVVWELESAGGQASSVVGSVYAAT
MMAR_1762|M.marinum_M               GSAQPAVVSWADFCAGGDGGAAGDAGVVVWEPNPAG---EDVVGSVYAAT
MUL_2005|M.ulcerans_Agy99           GSAQPAVVSWADFCAGGDGGAAGDAGVVVWEPNPAG---EDVVGPVYAAT
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      AGAESTSMCWPQQADHADNVDRFRAGIADGVTGVVVLTGPKNGNPDDAAA
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           HTALEVLQSWL--------GADRAATLVVLTHGGVGLAGEDISDLAAAAV
Rv2946c|M.tuberculosis_H37Rv        HTALEVLQSWL--------GADRAATLVVLTHGGVGLAGEDISDLAAAAV
MMAR_1762|M.marinum_M               HAALEVLQSWF--------DGDRAGTLVVLTHGAVAMPGENVSDLAGAAV
MUL_2005|M.ulcerans_Agy99           HAALEVLQSWF--------DGDRAGTLVVLTHGAVAMPGENVSDLAGAAV
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      RRGSDYVRHLVRITRELAEIDGDAPRLFVVTRGAQAVLPQDRPNLEQAGL
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           WGMARSAQAENPGRIVLIDTDAAVDASVLAGVGEPQLLVRGGTVHAPRLS
Rv2946c|M.tuberculosis_H37Rv        WGMARSAQAENPGRIVLIDTDAAVDASVLAGVGEPQLLVRGGTVHAPRLS
MMAR_1762|M.marinum_M               WGIVRSAQAENPGRIVLVDADAAVEAAELVAVGEPQLVVRSGAAHAARLA
MUL_2005|M.ulcerans_Agy99           WGIVRSAQAENPGRIVLVDADAAVEAAELVAVGEPQLVVRSGAAHAARLA
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      RGLLRVIGAEHPHLRTTQIDIADDADLDRVAVQLLGGGAEDETAWRDGQW
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           PAPALLALPAAESAWRLAAGGGGTLEDLVIQPCP----------EVQAPL
Rv2946c|M.tuberculosis_H37Rv        PAPALLALPAAESAWRLAAGGGGTLEDLVIQPCP----------EVQAPL
MMAR_1762|M.marinum_M               PAAPLLAVPADESAWRLAAGGGGTLEDLVIEPCP----------EVQAPL
MUL_2005|M.ulcerans_Agy99           PAAPLLAVPADESAWRLAAGGGGTLEDLVIEPCP----------EVQAPL
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      YTARLSLSPLRPEERKQAVVDCERDGMRLEIRTPGDLETMELAAFDRVPP
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           QAGQVRVAVAAVGVNFRDVVAALGMYP---GQAPPLGAEGAGVVLETGPE
Rv2946c|M.tuberculosis_H37Rv        QAGQVRVAVAAVGVNFRDVVAALGMYP---GQAPPLGAEGAGVVLETGPE
MMAR_1762|M.marinum_M               AAGQVRVAVRAVGVNFRDVVAALGMYP---GEAPPLGAEGAGVVLEVGPQ
MUL_2005|M.ulcerans_Agy99           AAGQVRVAVRAVGVNFRDVVAALGMYP---GAAPPLGAEGAGVVLEVGPQ
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      GPGQIEVAVTASSINFADVLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPD
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VTDLAVGDAVMGFLGG--AGPLAVVDQQLVTRVPQGWSFAQAAAVPVVFL
Rv2946c|M.tuberculosis_H37Rv        VTDLAVGDAVMGFLGG--AGPLAVVDQQLVTRVPQGWSFAQAAAVPVVFL
MMAR_1762|M.marinum_M               VSGVAVGDSVMGFLGG--AGPLSVVDQQLITRMPQGWSFAQAAAVPVVFL
MUL_2005|M.ulcerans_Agy99           VSGVAVGDSVMGFLGG--AGPLSVVDQQLITRMPQGWSFAQAAAVPVVFL
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      VTSHRVGDRVGGLSPNGCWSTFVTCDADLAVPLPDGLTEGQAAAVSTAHA
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           TAWYGLADLAEIKAGESVLIHAGTGGVGMAAVQLARQWGVEVFVTASRGK
Rv2946c|M.tuberculosis_H37Rv        TAWYGLADLAEIKAGESVLIHAGTGGVGMAAVQLARQWGVEVFVTASRGK
MMAR_1762|M.marinum_M               TALFGLQDLAKIQPGESVLIHAGTGGVGMAAVQLARHWGVEIFVTASRGK
MUL_2005|M.ulcerans_Agy99           TALFGLQDLAKIQPGESVLIHAGTGGVGMAAVQLARHWGVEIFVTASRGK
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      TAWYGLHDLARLGAGEKVLIHSATGGVGLAAIAIARSVGAQIYATAGSPA
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           WDTLRAMGFDDDHIGDSRTCEFEEKFLAVTEGRGVDVVLDSLAGEFVDAS
Rv2946c|M.tuberculosis_H37Rv        WDTLRAMGFDDDHIGDSRTCEFEEKFLAVTEGRGVDVVLDSLAGEFVDAS
MMAR_1762|M.marinum_M               WDTLRAMGFDDDHIGDSRTLDFEEKFLAVTDGRGVDVVLDSLAGDFVDAS
MUL_2005|M.ulcerans_Agy99           WDTLRAMGFDDDHIGDSRTLDFEEKFLAVTDGRGVDVVLDSLAGDFVDAS
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      RRDLLR-DMGIEHVYDSRSTAFADEIRRDTDGYGVDVVLNSLPGAAQRAG
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           LRLLVRGGRFLEMGKTDIR-----DAQEIAANYPGVQYRAFDLSEAGPAR
Rv2946c|M.tuberculosis_H37Rv        LRLLVRGGRFLEMGKTDIR-----DAQEIAANYPGVQYRAFDLSEAGPAR
MMAR_1762|M.marinum_M               LRLLVRGGRFLEMGKTDIR-----DADKIAANYPGVWYRAFDLSEAGPVR
MUL_2005|M.ulcerans_Agy99           LRLLVRGGRFLEMGKTDIR-----DADKIAANYPGVWYRAFDLSEAGPVR
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      LELLSFGGRFIEIGKRDIYGDTRLGLFPFRRNLAFHGVDLGLMADSHPHK
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           MQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTM
Rv2946c|M.tuberculosis_H37Rv        MQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTM
MMAR_1762|M.marinum_M               MQEMLAEVRELFDTAVLHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTM
MUL_2005|M.ulcerans_Agy99           MQEMLAEVRELFDTAVLHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTM
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      IRELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDV
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           PSALADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAE
Rv2946c|M.tuberculosis_H37Rv        PSALADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAE
MMAR_1762|M.marinum_M               PSALADGLADATVLITGATGAVGAVLARHMLDAYGVRHLVLASRRGDRAE
MUL_2005|M.ulcerans_Agy99           PSALADGLADATVLITGATGAVGAVLARHMLDGYGVRHLVLASRRGDRAE
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      PHTG----RADVVVPPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAAAGA
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GAAELAADLTEAGAKGQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAA
Rv2946c|M.tuberculosis_H37Rv        GAAELAADLTEAGAKVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAA
MMAR_1762|M.marinum_M               GAAELAAELSEAGANVQVVACDVADRDAVEAMLARLSGEYPPVRGVIHAA
MUL_2005|M.ulcerans_Agy99           GAAELAAELSEAGANVQVVACDVADRDAVEAMLARLSGEYPPVRGVIHAA
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      GCIVLNGRSAPSGEALRTIEQLRAAGTEVIVECGXXX-RGQPVEVAVPTE
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GVLDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSMFVLCSSIAA
Rv2946c|M.tuberculosis_H37Rv        GVLDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSMFALCSSIAA
MMAR_1762|M.marinum_M               GVLDDAVISSLTPERIDTVLRAKVDAAWNLHEATLDLDLSMFVLCSSIAA
MUL_2005|M.ulcerans_Agy99           GVLDDAVISSLTPERIDTVLRAKVDAAWNLHEATLDLDLSMFVLCSSIAA
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      LRHADEHPDRRGAQLCDEFARGEQGAQRNQHRTDAGEGQ----RDAHPPG
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           TVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISLAWGLWEQPGGMTAHLS
Rv2946c|M.tuberculosis_H37Rv        TVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISLAWGLWEQPGGMTAHLS
MMAR_1762|M.marinum_M               TVGSPGQGNYSAANSFLDGLAAHRQAAGLAGISVAWGLWEQSGGMAAHLS
MUL_2005|M.ulcerans_Agy99           TVGSPGQGNYSAANSFLDGLAAHRQAAGLAGISVAWGLWEQSGGMAAHLS
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      AVGHDQPDPGALSDTGLDERGGQFPGVGVQIPVADPGVGIDHRGAVRVDS
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           SRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAALDARAQ
Rv2946c|M.tuberculosis_H37Rv        SRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAALDARAQ
MMAR_1762|M.marinum_M               SRDLARMSRSGLAPMNPEQAVGLLDAVLAINHPLMVATLLDRPALEARAQ
MUL_2005|M.ulcerans_Agy99           SRDLARMSRSGLAPMNPEQAVGLLDAVLAINHPLMVATLLDRPALEARAQ
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      GVPAQQGVDGEVVRHRTLSSVRSGRSSRWTAPGSRCGSGRRYGGESCRRT
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           AGALPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLV
Rv2946c|M.tuberculosis_H37Rv        AGALPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLV
MMAR_1762|M.marinum_M               AGGLPPLFAGVVRRPRRRQIEDTGDAAQSKSALAERLNGLSAGERQDALV
MUL_2005|M.ulcerans_Agy99           AGGLPPLFAGVVRRPRRRQIEDTGDAAQSKSALAERLNGLSAGERQDALV
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      TGPAAGAAARRGRTRRRRRPRRPPPPPDRVRHRAGPAHGPVRR-------
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01653|M.leprae_Br4923          --------------------------------------------------
MAV_2194|M.avium_104                --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTL
Rv2946c|M.tuberculosis_H37Rv        GLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTL
MMAR_1762|M.marinum_M               GLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNRLKSATGLTL
MUL_2005|M.ulcerans_Agy99           GLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNRFKSATGLTL
MSMEG_6629|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_2779|M.gilvum_PYR-GCK          -------------------------------------------------
Mvan_3754|M.vanbaalenii_PYR-1       -------------------------------------------------
MAB_1879c|M.abscessus_ATCC_199      -------------------------------------------------
MLBr_01653|M.leprae_Br4923          -------------------------------------------------
MAV_2194|M.avium_104                -------------------------------------------------
Mb2971c|M.bovis_AF2122/97           PPTVIFDHPTPTAVAEYVAQQMSGSRPTESGDPTSQVVEPAAAEVSVHA
Rv2946c|M.tuberculosis_H37Rv        PPTVIFDHPTPTAVAEYVAQQMSGSRPTESGDPTSQVVEPAAAEVSVHA
MMAR_1762|M.marinum_M               PPTVIFDHPTPTAIAEYVGRQIPDSQATQAEE--EKLPESDGEMVSVTA
MUL_2005|M.ulcerans_Agy99           PPTVIFDHPTPTAIAEYVGRQIPDSQATQAEE--EKLPESDGEMVSVTA
MSMEG_6629|M.smegmatis_MC2_155      -------------------------------------------------
TH_4621|M.thermoresistible__bu      -------------------------------------------------