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M. smegmatis MC2 155 MSMEG_6293 (-)

annotation: transcriptional regulatory protein
coordinates: 6358686 - 6359258
length: 190

VAREPRRAPGTLTADDWLQAGYELLASDGMRALKIERLCEQVGATRGSFYWHFTDMKAYRAALVASWNTF
LENDRRSLAEMEDLPPRERLSKMIEALMSPQHWMLERAMREWARTDEIAAANVRAADHRVRMAVIKAFED
HGFDPDEARLRGEATFAAGIGMLHLIDSAEALATSGRPDRFLDIMLAPAS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6293--100% (190)transcriptional regulatory protein
M. smegmatis MC2 155MSMEG_0091-5e-0827.52% (109) putative transcriptional regulator
M. smegmatis MC2 155MSMEG_3874-1e-0532.43% (111) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4460-6e-5052.25% (178) TetR family transcriptional regulator
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3078-3e-1531.79% (151) TetR family transcriptional regulator
M. marinum MMMAR_3423-2e-4651.90% (158) putative transcriptional regulatory protein
M. avium 104MAV_2167-7e-6162.72% (169) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0904-3e-5554.55% (187) transcriptional regulatory protein
M. ulcerans Agy99MUL_2701-3e-4551.27% (158) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_1901-1e-5556.04% (182) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_6293|M.smegmatis_MC2_155      MAREPRRA----PGTLTADDWLQAGYELLASDGMRALKIERLCEQVGATR
MAV_2167|M.avium_104                -----------------------MGYTVLAEEGVRALKVERLCQQAGVTR
Mflv_4460|M.gilvum_PYR-GCK          MAKSGES-----AGRLSVDDWIQAGYAIIADEGRSALKIDRLCTRLGVTK
Mvan_1901|M.vanbaalenii_PYR-1       MPKGRAN-----TGRLSADDWIQAGYAILADDGLEALKLDRLCTRLGVTK
TH_0904|M.thermoresistible__bu      MTRPTDPRKPQVTARLSEEDWIQAGFAILAEEGIKALKLDRLCARLAVTK
MMAR_3423|M.marinum_M               MAGRGTSG----NRRLGVDDWVQAGFEILAEEGLSSLKLDQLCARLGVTK
MUL_2701|M.ulcerans_Agy99           MAGRSTSG----NRRLGVDDWVQAGFEILAEEGLISLKLDQLCARLGVTK
MAB_3078|M.abscessus_ATCC_1997      -----------MTEKVSRDDYFTAAFELLAAGGKSALTTTAVCRRIGMTT
                                                            .: ::*  *  :*.   :* : . * 

MSMEG_6293|M.smegmatis_MC2_155      GSFYWHFTDMKAYRAALVASWN-TFLENDRRSLAEMEDLPPRERLSKMIE
MAV_2167|M.avium_104                GSFYWHFEDIDNYRAALVESWN-KFLERDRQALAELDSLPPRERLSAMMG
Mflv_4460|M.gilvum_PYR-GCK          GSFYWHFRDMAAYRAALVQAWA-ELRDSDRSHFGDLGDLTPRERLTRMMA
Mvan_1901|M.vanbaalenii_PYR-1       GSFYWHFADMAAYRSALVHAWA-QLHDRDRRHFADLGHLTPRARLGQMMT
TH_0904|M.thermoresistible__bu      GSFYWHFESMAGFRRRLVESWA-ELRDRDRRDFDALGALPPRERLSRMMT
MMAR_3423|M.marinum_M               GSFYWHFADMEGYRHALVEAWA-QFRDEDRDEIEGLREVEPRERLALMMA
MUL_2701|M.ulcerans_Agy99           GSFYWHFADMEGYRHALVEAWA-QFRDEDRDEIEGLSEVEPRERLALMMA
MAB_3078|M.abscessus_ATCC_1997      GSLYHHFGSGAAFYRAVIDYWENDVTVAQRRRVDAVAD--PRERLATLEQ
                                    **:* ** .   :   ::  *   .   :*  .  :    ** **  :  

MSMEG_6293|M.smegmatis_MC2_155      ALMSPQHWMLERAMREWARTDEIAAANVRAADHRVRMAVIKAFEDHGFDP
MAV_2167|M.avium_104                TLVSPQYWMLERAMREWARLDPVAAENIRAADRHLLRTVTKAYRDYGFSP
Mflv_4460|M.gilvum_PYR-GCK          SLLGERQWTLERAMREWARTDPVVADSVHNADLLVLGAVRDAFLAAGFDD
Mvan_1901|M.vanbaalenii_PYR-1       SLLGERQWTLERAMREWARTDPGVAESVRAADHRVLDAVRHAFADAGFDA
TH_0904|M.thermoresistible__bu      ALTSPRHWMLERAMREWARTDSAAAASVRTADRRVLDAVRQAFLDHGFDP
MMAR_3423|M.marinum_M               LLARPRLWKLERAMREWARSDKTVAAAVLSADRRMVRAVQQAFCDYGFDA
MUL_2701|M.ulcerans_Agy99           LLARPRLWKLERAMREWARSDKTVAAAVLSADRRMVRAVQQAFCDYGFDA
MAB_3078|M.abscessus_ATCC_1997      AAR-EADHEVEKAIRSWAMADRYVAAAQQRVDQVRHEHLTKHYIEAGFTP
                                             :*:*:*.**  *  .*     .*      : . :   **  

MSMEG_6293|M.smegmatis_MC2_155      DEARLRGEATFAAGIGMLHLIDSAEA-------LATSGRPDR--FLDIML
MAV_2167|M.avium_104                EDAKLRAELTFAAGIGLLHLTGSAEQ-------AQSLAQRER--FLDLML
Mflv_4460|M.gilvum_PYR-GCK          DDADVRANATFAAGIGFLHLSAAPPD-------ARLTEQRER--FLDLML
Mvan_1901|M.vanbaalenii_PYR-1       DEADMRANAVFAAGIGFLHLSDAPPG-------ARMDAQRER--FLDLML
TH_0904|M.thermoresistible__bu      ADADLRANATFAAGIGFLHLAGDRPG-------AHGIAHRER--FLELML
MMAR_3423|M.marinum_M               DEAEMRANTAFAAGLGLLHMSGSALKGLFGSALKRQTAAPERNWFLEFLL
MUL_2701|M.ulcerans_Agy99           DEAEMRANTAFAAVLGLLHMSGSALKGLFGSALKRQTAAPERNWFLEFLL
MAB_3078|M.abscessus_ATCC_1997      ARADTLARIGFSILVGAQQFGTRVDHK------RLNSALDEYSAWVNSSV
                                      *   ..  *:  :*  ::                    :   :::  :

MSMEG_6293|M.smegmatis_MC2_155      APAS-----
MAV_2167|M.avium_104                TEAGVASDH
Mflv_4460|M.gilvum_PYR-GCK          SR-------
Mvan_1901|M.vanbaalenii_PYR-1       AR-------
TH_0904|M.thermoresistible__bu      TP-------
MMAR_3423|M.marinum_M               RE-------
MUL_2701|M.ulcerans_Agy99           RE-------
MAB_3078|M.abscessus_ATCC_1997      SAEVTTSH-