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PKGRANTGRLSADDWIQAGYAILADDGLEALKLDRLCTRLGVTKGSFYWHFADMAAYRSALVHAWAQLHD RDRRHFADLGHLTPRARLGQMMTSLLGERQWTLERAMREWARTDPGVAESVRAADHRVLDAVRHAFADAG FDADEADMRANAVFAAGIGFLHLSDAPPGARMDAQRERFLDLMLAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1901 | - | - | 100% (187) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5303 | - | 4e-18 | 32.34% (167) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0102 | - | 4e-11 | 30.28% (142) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4460 | - | 2e-78 | 75.94% (187) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3078 | - | 3e-14 | 33.14% (175) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3423 | - | 3e-54 | 60.74% (163) | putative transcriptional regulatory protein |
| M. avium 104 | MAV_2167 | - | 1e-48 | 54.22% (166) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6293 | - | 1e-55 | 56.04% (182) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0904 | - | 3e-66 | 66.30% (184) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_2701 | - | 3e-53 | 60.98% (164) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1901|M.vanbaalenii_PYR-1 MPKGRAN-----TGRLSADDWIQAGYAILADDGLEALKLDRLCTRLGVTK
Mflv_4460|M.gilvum_PYR-GCK MAKSGES-----AGRLSVDDWIQAGYAIIADEGRSALKIDRLCTRLGVTK
TH_0904|M.thermoresistible__bu MTRPTDPRKPQVTARLSEEDWIQAGFAILAEEGIKALKLDRLCARLAVTK
MAV_2167|M.avium_104 -----------------------MGYTVLAEEGVRALKVERLCQQAGVTR
MSMEG_6293|M.smegmatis_MC2_155 MAREPRRA----PGTLTADDWLQAGYELLASDGMRALKIERLCEQVGATR
MMAR_3423|M.marinum_M MAGRGTSG----NRRLGVDDWVQAGFEILAEEGLSSLKLDQLCARLGVTK
MUL_2701|M.ulcerans_Agy99 MAGRSTSG----NRRLGVDDWVQAGFEILAEEGLISLKLDQLCARLGVTK
MAB_3078|M.abscessus_ATCC_1997 -----------MTEKVSRDDYFTAAFELLAAGGKSALTTTAVCRRIGMTT
.: ::* * :*. :* : . *
Mvan_1901|M.vanbaalenii_PYR-1 GSFYWHFADMAAYRSALVHAWA-QLHDRDRRHFADLGHLTPRARLGQMMT
Mflv_4460|M.gilvum_PYR-GCK GSFYWHFRDMAAYRAALVQAWA-ELRDSDRSHFGDLGDLTPRERLTRMMA
TH_0904|M.thermoresistible__bu GSFYWHFESMAGFRRRLVESWA-ELRDRDRRDFDALGALPPRERLSRMMT
MAV_2167|M.avium_104 GSFYWHFEDIDNYRAALVESWN-KFLERDRQALAELDSLPPRERLSAMMG
MSMEG_6293|M.smegmatis_MC2_155 GSFYWHFTDMKAYRAALVASWN-TFLENDRRSLAEMEDLPPRERLSKMIE
MMAR_3423|M.marinum_M GSFYWHFADMEGYRHALVEAWA-QFRDEDRDEIEGLREVEPRERLALMMA
MUL_2701|M.ulcerans_Agy99 GSFYWHFADMEGYRHALVEAWA-QFRDEDRDEIEGLSEVEPRERLALMMA
MAB_3078|M.abscessus_ATCC_1997 GSLYHHFGSGAAFYRAVIDYWENDVTVAQRRRVDAVAD--PRERLATLEQ
**:* ** . : :: * . :* . : ** ** :
Mvan_1901|M.vanbaalenii_PYR-1 SLLGERQWTLERAMREWARTDPGVAESVRAADHRVLDAVRHAFADAGFDA
Mflv_4460|M.gilvum_PYR-GCK SLLGERQWTLERAMREWARTDPVVADSVHNADLLVLGAVRDAFLAAGFDD
TH_0904|M.thermoresistible__bu ALTSPRHWMLERAMREWARTDSAAAASVRTADRRVLDAVRQAFLDHGFDP
MAV_2167|M.avium_104 TLVSPQYWMLERAMREWARLDPVAAENIRAADRHLLRTVTKAYRDYGFSP
MSMEG_6293|M.smegmatis_MC2_155 ALMSPQHWMLERAMREWARTDEIAAANVRAADHRVRMAVIKAFEDHGFDP
MMAR_3423|M.marinum_M LLARPRLWKLERAMREWARSDKTVAAAVLSADRRMVRAVQQAFCDYGFDA
MUL_2701|M.ulcerans_Agy99 LLARPRLWKLERAMREWARSDKTVAAAVLSADRRMVRAVQQAFCDYGFDA
MAB_3078|M.abscessus_ATCC_1997 AAR-EADHEVEKAIRSWAMADRYVAAAQQRVDQVRHEHLTKHYIEAGFTP
:*:*:*.** * .* .* : . : **
Mvan_1901|M.vanbaalenii_PYR-1 DEADMRANAVFAAGIGFLHLSDAPPG-------ARMDAQRER--FLDLML
Mflv_4460|M.gilvum_PYR-GCK DDADVRANATFAAGIGFLHLSAAPPD-------ARLTEQRER--FLDLML
TH_0904|M.thermoresistible__bu ADADLRANATFAAGIGFLHLAGDRPG-------AHGIAHRER--FLELML
MAV_2167|M.avium_104 EDAKLRAELTFAAGIGLLHLTGSAEQ-------AQSLAQRER--FLDLML
MSMEG_6293|M.smegmatis_MC2_155 DEARLRGEATFAAGIGMLHLIDSAEA-------LATSGRPDR--FLDIML
MMAR_3423|M.marinum_M DEAEMRANTAFAAGLGLLHMSGSALKGLFGSALKRQTAAPERNWFLEFLL
MUL_2701|M.ulcerans_Agy99 DEAEMRANTAFAAVLGLLHMSGSALKGLFGSALKRQTAAPERNWFLEFLL
MAB_3078|M.abscessus_ATCC_1997 ARADTLARIGFSILVGAQQFGTRVDHK------RLNSALDEYSAWVNSSV
* .. *: :* :: : ::: :
Mvan_1901|M.vanbaalenii_PYR-1 AR-------
Mflv_4460|M.gilvum_PYR-GCK SR-------
TH_0904|M.thermoresistible__bu TP-------
MAV_2167|M.avium_104 TEAGVASDH
MSMEG_6293|M.smegmatis_MC2_155 APAS-----
MMAR_3423|M.marinum_M RE-------
MUL_2701|M.ulcerans_Agy99 RE-------
MAB_3078|M.abscessus_ATCC_1997 SAEVTTSH-