For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RRAPHPLALIAGLAIITSGAAAGCTVANTAHGGYDPDTLRIVLPQEPPTLEPCESSLTSTGVVVRSNITE PLIERDPQTGDLLPLLATGWHQTSPREWTFDIRPGVTFSDGTPFTAADAAFSIDRAVNSDLQCNVDGYVF GDDPLKVSAPDDHTVVVGTAKPDPILPLRISFIEIVPHTTSVTEKVREPIGTGPYAIERWEYGQKLVLHR NERYWGAAPDFTRAEYQWRSEGSVRAAMVVNDEADIGTSVGPEDGAGDLGVPFPNNETTALRLTATEPPL DDLRVRQAINYSVNRTGIVKALYRGLGEPAAQLIPEGVVGHNEDLELWPYDPDRARELIDEARADGVPVD REIRLIGRNSLFPKVTETVEVIQNELSKIGLNVKIEMMDTAAQLQYQLRPFPPNAGAFIALIQHGNQAGD AAFSVDQYMRSDGAQSAYGTPEFDARIEAAGELTGEQRQQAYAQIFADEPDEIAQFAYIAHMTGVLAKSP RVDYQPNSATGDEMRLSQMTFAADDTVEH*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6124 | - | - | 100% (520) | putative ABC transporter periplasmic oligopeptide-binding protein |
M. smegmatis MC2 155 | MSMEG_6865 | - | 2e-35 | 26.16% (497) | ABC transporter solute binding lipoprotein |
M. smegmatis MC2 155 | MSMEG_4354 | - | 5e-35 | 27.95% (483) | dipeptide-binding protein of ABC transport system |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1311c | oppA | 5e-12 | 24.34% (415) | periplasmic oligopeptide-binding lipoprotein OppA |
M. gilvum PYR-GCK | Mflv_2761 | - | 1e-35 | 27.47% (517) | extracellular solute-binding protein |
M. tuberculosis H37Rv | Rv1280c | oppA | 5e-12 | 24.34% (415) | periplasmic oligopeptide-binding lipoprotein OppA |
M. leprae Br4923 | MLBr_01121 | - | 7e-11 | 24.11% (423) | putative extracellular solute-binding dependent transport |
M. abscessus ATCC 19977 | MAB_0426 | - | 1e-14 | 25.13% (382) | peptide ABC transporter DppA |
M. marinum M | MMAR_4139 | oppA | 1e-11 | 25.15% (517) | periplasmic oligopeptide-binding lipoprotein OppA |
M. avium 104 | MAV_3421 | - | 1e-10 | 23.90% (318) | extracellular solute-binding protein, family protein 5 |
M. thermoresistible (build 8) | TH_4152 | - | 4e-38 | 28.17% (497) | PUTATIVE extracellular solute-binding protein, family 5 |
M. ulcerans Agy99 | MUL_4002 | oppA | 9e-11 | 24.95% (517) | periplasmic oligopeptide-binding lipoprotein OppA |
M. vanbaalenii PYR-1 | Mvan_1024 | - | 0.0 | 75.10% (514) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_6124|M.smegmatis_MC2_155 -----------------------------MR--RAPHPLALIAGLAIITS Mvan_1024|M.vanbaalenii_PYR-1 -----------------------------MNPSTALKPRRLVAGLALATV Mflv_2761|M.gilvum_PYR-GCK -----------------------------MARTAVGAAVLAVCALVLSLT TH_4152|M.thermoresistible__bu -------------------------------------VSNLVAVLLIAAT Mb1311c|M.bovis_AF2122/97 MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT Rv1280c|M.tuberculosis_H37Rv MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT MMAR_4139|M.marinum_M MLTNADR---HDGVQPGPGARSRRPTRPWAR-RRIRCAGAALLTVTLLLA MUL_4002|M.ulcerans_Agy99 -----------------------------------------MLTVTLLLA MLBr_01121|M.leprae_Br4923 -------------------------------MIMLSRIVAALLVVGLILT MAB_0426|M.abscessus_ATCC_1997 -----------------------------------MRLRRLAIVLLVGIV MAV_3421|M.avium_104 ------------------------------MAKVASRTATLGAMLCVLAA : : MSMEG_6124|M.smegmatis_MC2_155 GAAAG-CTVANTAHGG-------------------YDPDTLRIVLPQEPP Mvan_1024|M.vanbaalenii_PYR-1 TVATGGCTVANSGGGG-------------------YDPDTLRIVLQQEPP Mflv_2761|M.gilvum_PYR-GCK GCNTG----ERVDLGD-------------------GAGGALIAAIAGEPD TH_4152|M.thermoresistible__bu GCAPG----QRVDLGD-------------------LSG-NLIAAIAGEPD Mb1311c|M.bovis_AF2122/97 GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP Rv1280c|M.tuberculosis_H37Rv GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP MMAR_4139|M.marinum_M GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP MUL_4002|M.ulcerans_Agy99 GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP MLBr_01121|M.leprae_Br4923 GCSAS-NRLVPSAASN--AALGKTSDINPQDPATLKDGGNLRLALTDFPA MAB_0426|M.abscessus_ATCC_1997 AVLPAGCGDLVTPAP----------------------PGYFSMYITEPEH MAV_3421|M.avium_104 GCSGHRHTASTGPTGP----------------------PVRGGTLTYSDV : MSMEG_6124|M.smegmatis_MC2_155 TLEPCESSLTSTGVVVRSNITEP---LIERDPQTGDLLPLLATGWHQTS- Mvan_1024|M.vanbaalenii_PYR-1 TLEPCESSLTSTGIVVRSNITEP---LLERDANTGELQPLLSTGWEQTS- Mflv_2761|M.gilvum_PYR-GCK QLDPHKTTAYFS-FEVLENVFDT---LVEPD-QDLQMKPALAESWEVSPD TH_4152|M.thermoresistible__bu QLDPHKTSAYFS-FQVLENVFDT---LVEPD-EDLRMRPALAESWQVSAD Mb1311c|M.bovis_AF2122/97 NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA Rv1280c|M.tuberculosis_H37Rv NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA MMAR_4139|M.marinum_M NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN MUL_4002|M.ulcerans_Agy99 NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN MLBr_01121|M.leprae_Br4923 NFNILHIDGNNAEVTSMMKATMPRAFIIGTDGSTTVDTNYFTSIKLTSTS MAB_0426|M.abscessus_ATCC_1997 TLVPGNTTENQGGRILRSLFTAL----VEFNNETAAVEYTGVAESITSHD MAV_3421|M.avium_104 QFVTDTMAANYSANNLMFQLLDR---VVYVDPKTDAVRGWLAKTFSRNQN : : : . MSMEG_6124|M.smegmatis_MC2_155 PREWTFDIRPGVTFSDGTPFTAA-------DAAFSIDRAVNSDLQCNVDG Mvan_1024|M.vanbaalenii_PYR-1 PNEWTFTLRDGVTFSDGAPFTSA-------DAAFSIDRAVNSDLQCNVDG Mflv_2761|M.gilvum_PYR-GCK QLTWTFRLRPGVTFHDGTPLAAE-------DVVFSYRRIIDEQLANSDK- TH_4152|M.thermoresistible__bu QRVWTFRLRPGVTFHDGSPLTAD-------DVVFSYRRIIDEHLTNVDR- Mb1311c|M.bovis_AF2122/97 PQVVTYTINPEAVWSDGTPITWR-------DIASQIHAISGADKAFEIAS Rv1280c|M.tuberculosis_H37Rv PQVVTYTINPEAVWSDGTPITWR-------DIASQIHAISGADKAFEIAS MMAR_4139|M.marinum_M PQVITYTINPKAFWSDGTPITWR-------DIASQIHATSGADNRFEIAS MUL_4002|M.ulcerans_Agy99 PQVITYTINPKAFWSDGTPVTWR-------DIASQIHATSGADNRFEIAS MLBr_01121|M.leprae_Br4923 PQVVTYTINPKAVWSDGTPITWR-------DIDRQIHANSGKNKAFEIAG MAB_0426|M.abscessus_ATCC_1997 NVNWTIKLKPGWTFHNGEPVTAQSYVDAWNYTALSTNAQGSSSFLANVDG MAV_3421|M.avium_104 ATRYTFTIRDGVSFSDHTPLTAE-------VVKANFDQLGKGDPAKKMPA * :. : : *.: . MSMEG_6124|M.smegmatis_MC2_155 YVFGDDPLKVSA------------PDDHTVVVGTAKPDPILPLRIS---- Mvan_1024|M.vanbaalenii_PYR-1 YVFGDEKLGLQT------------PNPSTVVVSTTKPDPILPLRIS---- Mflv_2761|M.gilvum_PYR-GCK ---FSSVQAVEA------------PDPSTVVIRVDRPTPNMLTNLGG--- TH_4152|M.thermoresistible__bu ---LSAVTEVTA------------VDPLTVRITVARPTPNLLTNLGG--- Mb1311c|M.bovis_AF2122/97 SSGAERVASVTRG-----------VDDRQAVVTFAKPYAEWRGMFAGNGM Rv1280c|M.tuberculosis_H37Rv SSGAERVASVTRG-----------VDDRQAVVTFAKPYAEWRGMFAGNGM MMAR_4139|M.marinum_M SGGSDRVASVTPG-----------VDDRQAIVTFAKPYAEWRGMFAGNGM MUL_4002|M.ulcerans_Agy99 SGGSDRVASVIPG-----------VDDRQAMVTFAKPYAEWRGMFAGNGM MLBr_01121|M.leprae_Br4923 TNGCERVASIRPG-----------ANDRQAIVTFAQPYAEWRGMFAGNGM MAB_0426|M.abscessus_ATCC_1997 FDDLQGDPAHKIAPRATQMRGLHVVDDVTFTVRLNTPFAIYPMTLG---- MAV_3421|M.avium_104 FADFVGYDHSEVS-------------GNVVTVFLDRPNTNFYKVLSYSRA : * . :. MSMEG_6124|M.smegmatis_MC2_155 ---FIEIVPHTTSVTEKVR-EPIGTGPYAIERWE-YGQKLVLHRNERYWG Mvan_1024|M.vanbaalenii_PYR-1 ---FVEMVPRTTSTTEKVR-EPIGTGPYAIERWD-YGQKLVLARNATYWG Mflv_2761|M.gilvum_PYR-GCK -FKGMAIVSRANVESGRIATHPVGTGPFSFLGQK-SGDSISLRANPDYWA TH_4152|M.thermoresistible__bu -FKGMAIVQRANVETGRIATHPVGTGPFEFRGAR-SGDSITLVANDDHWA Mb1311c|M.bovis_AF2122/97 LLPASMTATPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG Rv1280c|M.tuberculosis_H37Rv LLPASMTATPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG MMAR_4139|M.marinum_M LLPSSMTATPEAFNKGQLAGPGPSAGPFIVTSLDRSAQRIVLTRNPKWWG MUL_4002|M.ulcerans_Agy99 LLPSSMTATPEAFNKGQLTGPGPSAGPFIVTSLDRSAQRIVLIRNPKWWG MLBr_01121|M.leprae_Br4923 LLPATMTATPEAFNKGQLDRPGPSAGPFIVSSLDRTTQRIVLTHNPKWWG MAB_0426|M.abscessus_ATCC_1997 YTAFLPLPKAFFRDPVKFGVHPIGNGPFKADGDWVRGVGFTLSRYDQYAG MAV_3421|M.avium_104 GIRAPATLALDYQRQAKVE-NVIGSGPFVYQSQIPDQQVVLTRRPDYAWP :. . **: . MSMEG_6124|M.smegmatis_MC2_155 -------AAPDFTRAEYQWRSEGSVRAAMVVNDEADIGTSVGPE------ Mvan_1024|M.vanbaalenii_PYR-1 -------QAPSFAKAEYQWRSEGSVRAAMITNDEADIATGLGPE------ Mflv_2761|M.gilvum_PYR-GCK -------GPPGVAGVTFRFIPEPSTALSALQAGEVDWTDSVPPQRVSQLR TH_4152|M.thermoresistible__bu -------GPPRLNGVTFRFISEPATALSALQAGEIDWTDAIPTQRVTQLR Mb1311c|M.bovis_AF2122/97 -------ARPRLDSITYLVLDD-AARLPALQNNTIDATGVGTLDQLTIAA Rv1280c|M.tuberculosis_H37Rv -------ARPRLDSITYLVLDD-AARLPALQNNTIDATGVGTLDQLTIAA MMAR_4139|M.marinum_M -------KKPRLDSITYLVLDD-AARIPALQNFTIDATGIGSLDQLTIAE MUL_4002|M.ulcerans_Agy99 -------KKPRLHSITYLVLDD-AARIPALQNFTIDATGIGSLDQLTIAE MLBr_01121|M.leprae_Br4923 -------TPPRLDSITYLVLDD-AARLPALQNNTIDATGVGTLDQLTTAQ MAB_0426|M.abscessus_ATCC_1997 E------KKAKAKGLIWRVYTEGLTAYTDMQAGALDIQLDLPDAAYENAK MAV_3421|M.avium_104 PSSWPNQGPAYVDKVVFRVIGEPGLRAGAVQSHQVDVARGIQPTDEPALK . : : : * MSMEG_6124|M.smegmatis_MC2_155 DGAGDLGVPFPNNETTALRLT-ATEPPLDDLRVRQAINYSVNRTGIVKAL Mvan_1024|M.vanbaalenii_PYR-1 DGAGDLGVPFQNNETTALRMQ-ATEPPLDDIRVRQAINYAVNRTGIVKAL Mflv_2761|M.gilvum_PYR-GCK DDESLQLTVTPSNDYWYLALN-QARAPWNDVRVRQAIAYAIDRDAIVQAT TH_4152|M.thermoresistible__bu NDDSLTLAVTPSNDYWYLALN-HARAPWHDLRVRRAIAFGIDREAIVTAT Mb1311c|M.bovis_AF2122/97 RTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKGIDRYTIARVA Rv1280c|M.tuberculosis_H37Rv RTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKGIDRYTIARVA MMAR_4139|M.marinum_M RTKGISIRRAPAPSWSHFTLNGAPGAVLADPALRLAVCKGIDRRTIAKVA MUL_4002|M.ulcerans_Agy99 RTKGISIRRAPAPSWSHFTLNGAPGAVLADPALRLAVCKGIDRRTIAKVA MLBr_01121|M.leprae_Br4923 RTNGISIRRTPAPRWSHFTFNGAVGSILADQGLRLAVSKGIDRRTIAKVV MAB_0426|M.abscessus_ATCC_1997 AEFGSAYLERPRPDITSLGFP-MYDPRYRDVRVRQAISMAIDREAITQVI MAV_3421|M.avium_104 QGGLQVIPVAAPAETANLVGFRINNQVVDDVRVRRALQLGIDRRAVVDTV : * :* *: .::* :. . MSMEG_6124|M.smegmatis_MC2_155 YRGLGEP----AAQLIPEGVVGHNEDLELWPYD----PDRARELIDEARA Mvan_1024|M.vanbaalenii_PYR-1 FRDLGQP----AAQLIPSGVVGYNAELQLWPHD----LDKARALIEEARA Mflv_2761|M.gilvum_PYR-GCK SYGTAAA----NQLAIPEGNP-WFTPYDRYREDGEEGLETARDLLRQANA TH_4152|M.thermoresistible__bu GYGTATA----NQLAIPPGDF-WYTHYDRYRYD----LDRARALLDEARA Mb1311c|M.bovis_AF2122/97 QYGLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQ-AKRELDALGWRRS Rv1280c|M.tuberculosis_H37Rv QYGLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQ-AKRELDALGWRRS MMAR_4139|M.marinum_M LYGLTNDPAPLNNHVFVAGQEGYQDNS--SPYDPEQ-AKRELDALGWKLN MUL_4002|M.ulcerans_Agy99 LYGLTNDPAPLNNHVFVAGQEGYQDNS--SPYDPEQ-AKRELDALGWKLN MLBr_01121|M.leprae_Br4923 QYGLANNPEPLNNHVYVDGQEGYQDNSGVVGYDPEQ-AQHELDALGWKLN MAB_0426|M.abscessus_ATCC_1997 FSGTRTP------ATSYGSAVVYGYRKGACGKLCELHVDEANKLLDEAHF MAV_3421|M.avium_104 LSDSYRA----ADSVLGHDDPLFADVSADIGYQPQRAAGLLDAAGWKPGG . . MSMEG_6124|M.smegmatis_MC2_155 DGVPVDREIRLIGRNSLFPKVTET---VEVIQNELSKIGLNVKIEMMDTA Mvan_1024|M.vanbaalenii_PYR-1 DGVPVDREIRLIGRTAQFPKITET---IEVLQSEFTEIGLNVKIEMMDTA Mflv_2761|M.gilvum_PYR-GCK T----PGDLDMLVTT-EYPETVTA---AQIVADNLAPLGITVNIRTVDFA TH_4152|M.thermoresistible__bu AGVDPPRRLDMLVTG-DYPQTVTA---AQIIADNVAPLGITVDIRTVDFA Mb1311c|M.bovis_AF2122/97 GAFREKDGRQLVIRDLFYDAQSTRQ-FAQIAQHTLAQIGVKLELQAKSGS Rv1280c|M.tuberculosis_H37Rv GAFREKDGRQLVIRDLFYDAQSTRQ-FAQIAQHTLAQIGVKLELQAKSGS MMAR_4139|M.marinum_M GKFREKDGHQLVVRLLFYEAQSSRQ-FAQVAQYSLAQIGVKLELQSRSGS MUL_4002|M.ulcerans_Agy99 GKFREKDGHQLVVRLLFYEAQSSRQ-FAQVAQYSLAQIGVKLELQSRSGS MLBr_01121|M.leprae_Br4923 GQFREKDGRQLVIRYLFYDAQGSRE-FAQLAQHSLAQIGVKLELQAKAGS MAB_0426|M.abscessus_ATCC_1997 D-----RNKPIELWYSSSSTGALSW-VQAIGNQLQSNLKVPYLLKSLPWS MAV_3421|M.avium_104 DGVREKDGKKLVLTLAASNQSVVFRPAFEFIEQQWRELGVVLQNRAGDTT : . : : . : MSMEG_6124|M.smegmatis_MC2_155 AQLQYQLRPFPPNAGAFIALIQHGNQA--GDAAFSVDQYMRSDGAQSAYG Mvan_1024|M.vanbaalenii_PYR-1 AQLEYQLRPFPPDTGPYLLMIMHGNQA--GDAAFTLDQYMLSDGPQAAYG Mflv_2761|M.gilvum_PYR-GCK TWLDEQNS----GNFDMLMMGWLGNID--PDDFYYAQHHTDGTSNAQKFS TH_4152|M.thermoresistible__bu TWLDEQNN----GTFDMLMMGWLGNID--PDDYYYAQHHTDGASNAQRFS Mb1311c|M.bovis_AF2122/97 GFFSDYVN---VGAFDIAQFGWVGDAF--PLSSLTQIYASDGESNFGKIG Rv1280c|M.tuberculosis_H37Rv GFFSDYVN---VGAFDIAQFGWVGDAF--PLSSLTQIYASDGESNFGKIG MMAR_4139|M.marinum_M GFFSNYVN---VGAFDIALFGWVGDAF--PLSSLTQIYMSDGESNFGKIG MUL_4002|M.ulcerans_Agy99 GFFSNYVN---VGAFDIALFGWVGDAF--PLSSLTQIYMSDGESNFGKIG MLBr_01121|M.leprae_Br4923 GFFTNYVN---VGAFDIVQFGWVGDAF--PLSALTQIYQSDGESNFGKIS MAB_0426|M.abscessus_ATCC_1997 QFLPLQDGKGMTGPFRSGWVMDYPSIYNFLESLYGTVALPPNGSNYVFYS MAV_3421|M.avium_104 FFNASSSQ----SSTPLFGTRIQYNIG-------LGLLFGRPKSNLTFAQ . . . MSMEG_6124|M.smegmatis_MC2_155 TPEFDARIEAAGELTGEQRQQAYAQIFADEPDEIAQFAYIAHMTGVLAKS Mvan_1024|M.vanbaalenii_PYR-1 TPEFDARIRTAEALTGQARQDAFAALFAEEPQEIVQMAYIAHMKGILGKS Mflv_2761|M.gilvum_PYR-GCK NPEVDRLLDAGRVETDEQTRKAGYARAATLIADEVSYIYLYNPSVIQAWN TH_4152|M.thermoresistible__bu DPEVDRLLDAARAEPDRDRRKALYDRAATLIADRVSYLFLYNPAVVQAWS Mb1311c|M.bovis_AF2122/97 SPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSPGTVAVR Rv1280c|M.tuberculosis_H37Rv SPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSPGTVAVR MMAR_4139|M.marinum_M SPQIDAAIERTLQELDPAKALALANEVDKLIWAEGFSLPLTQSPGTIAVR MUL_4002|M.ulcerans_Agy99 SPQIDAAIERTLQELDPAKALALANQVDKLIWAEGFSLPLTQSPGTIAVR MLBr_01121|M.leprae_Br4923 SPAVDAAIERTLAELDPAKARALANEVDKLLWAEGFSLPLTQSPGDVAVR MAB_0426|M.abscessus_ATCC_1997 NPAFDELLRQGNNEPTVELATKAYQKAEDLLFKDLPAAPLFYEVNQAVHS MAV_3421|M.avium_104 NDALLALSEEELRQTDPTRLKDVVAREQRRIIDDQLALVLWDEVQVHAAA . : MSMEG_6124|M.smegmatis_MC2_155 PRVD-YQPNSATGDEMRLSQMTFAADDTVEH- Mvan_1024|M.vanbaalenii_PYR-1 ERID-YTPNPATGDEMLLAAMTPAGNDRTDQS Mflv_2761|M.gilvum_PYR-GCK PALSGYEARRDGAVRFRSASLDSDGNV----- TH_4152|M.thermoresistible__bu PDLSGYRARRDAAVRFRDASLNRDGLNRDGPP Mb1311c|M.bovis_AF2122/97 STLANFGATGLADLDYTAIGFMRR-------- Rv1280c|M.tuberculosis_H37Rv STLANFGATGLADLDYTAIGFMRR-------- MMAR_4139|M.marinum_M STLANFGARGLADLDYTAIGFMRS-------- MUL_4002|M.ulcerans_Agy99 STLANFGARGLADLDYTAIGFMRS-------- MLBr_01121|M.leprae_Br4923 STLANFGAAGFGDLNYTAIGFMQN-------- MAB_0426|M.abscessus_ATCC_1997 KRVRNVKIGIQDCIEYADVEVVQ--------- MAV_3421|M.avium_104 PNVHVEFTRYTEPLLQSAWKA----------- :