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RTLAVSVALAAPFALAACGSDESSTAEPAGDCPTTPVNVVVSVDQWGDIVSELGGACAKVTTVLAGSSVD PHDFEPSPSDAAKFEGAQLVVINGGHYDEWAGKLARSSAPNAPVVAAVADAGAHEDDAHDHGHDEHGHAH AEEGVNPHAWYSPAAVTTVADEVTAKLGDLAPEAKDYFAERRAAFTESMKPYNQLIDDIKAKASGKTYAA TEAVFDDMAAAVGLTDRTPPGYQVASSNETDPSPADFDAFLTLLENRGVDVLIYNVQTEGSVPQQLRTAA ESAGIPVVEVTETVAPGADSFEAWQVDQLTALAKALGVES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6047 | - | - | 100% (321) | cation ABC transporter, periplasmic cation-binding protein, putative |
| M. smegmatis MC2 155 | MSMEG_6050 | - | 8e-14 | 26.80% (306) | solute-binding lipoprotein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2085 | - | 1e-33 | 32.03% (256) | hypothetical protein Mb2085 |
| M. gilvum PYR-GCK | Mflv_1454 | - | 1e-114 | 63.58% (324) | periplasmic solute binding protein |
| M. tuberculosis H37Rv | Rv2059 | - | 1e-33 | 32.03% (256) | hypothetical protein Rv2059 |
| M. leprae Br4923 | MLBr_00337 | - | 7e-31 | 29.34% (317) | putative periplasmic solute-binding proteins |
| M. abscessus ATCC 19977 | MAB_0577c | - | 1e-41 | 34.17% (319) | ABC transporter solute-binding protein |
| M. marinum M | MMAR_5071 | - | 2e-33 | 30.91% (317) | hypothetical protein MMAR_5071 |
| M. avium 104 | MAV_0583 | - | 3e-38 | 36.08% (316) | periplasmic solute binding protein family protein |
| M. thermoresistible (build 8) | TH_1746 | - | 4e-40 | 34.20% (307) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4147 | - | 6e-33 | 29.94% (314) | hypothetical protein MUL_4147 |
| M. vanbaalenii PYR-1 | Mvan_5320 | - | 1e-120 | 64.39% (337) | periplasmic solute binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2085|M.bovis_AF2122/97 --------MATPVILVTGHEGTAAVTADLLGLLT--DHGTATLRSVAPG-
Rv2059|M.tuberculosis_H37Rv --------MATPVILVTGHEGTAAVTADLLGLLT--DHGTATLRSVAPG-
MMAR_5071|M.marinum_M ------------MLRVRVAHGFSAILLSVLGATG--VAACGTDHDAHPG-
MUL_4147|M.ulcerans_Agy99 -------------MRVRVAHGFSAILLSVLGATG--VAACGTDHDAHPG-
MLBr_00337|M.leprae_Br4923 ------------------MRWLTTIILCLISSTV--AGGCGSLSSGHLR-
MAV_0583|M.avium_104 --------MGTALTRDATRVGRTTRWLATVLAVTGWAALTGCTGPAHPH-
TH_1746|M.thermoresistible__bu -----------------------------VSAVAFGSAACGQDRDVHQEH
MAB_0577c|M.abscessus_ATCC_199 -----------------MPARVAGLAVAVATAGTLALSGCG-QSHERSG-
Mflv_1454|M.gilvum_PYR-GCK MKTVIVCAMLRSTRRGRALAG-IAASAALVLTACGGSGNTGAGDEASAGD
Mvan_5320|M.vanbaalenii_PYR-1 --------MISSFRGVRVLAATLAVSLPFVLSACGGD-DTSAMDTSAAPD
MSMEG_6047|M.smegmatis_MC2_155 ---------------MRTLAVSVALAAPFALAACGSD---ESSTAEPAGD
Mb2085|M.bovis_AF2122/97 -SVRRADPRPRCHRREQRRRHRASMKSAIHPDHHPRRLPRCPVLRRDQVV
Rv2059|M.tuberculosis_H37Rv -SVRRADPRPRCHRREQRRRHRASMKSAIHPDHHPRRLPRCPVLRRDQVV
MMAR_5071|M.marinum_M -AAAVVAST-----------------------------------------
MUL_4147|M.ulcerans_Agy99 -AAAVVAST-----------------------------------------
MLBr_00337|M.leprae_Br4923 -PTAVVAST-----------------------------------------
MAV_0583|M.avium_104 -ATAVVAST-----------------------------------------
TH_1746|M.thermoresistible__bu RAATVVAST-----------------------------------------
MAB_0577c|M.abscessus_ATCC_199 -ALTVVAST-----------------------------------------
Mflv_1454|M.gilvum_PYR-GCK CPAAPVDVVVS---------------------------------------
Mvan_5320|M.vanbaalenii_PYR-1 CPTTPVNVVVS---------------------------------------
MSMEG_6047|M.smegmatis_MC2_155 CPTTPVNVVVS---------------------------------------
. .
Mb2085|M.bovis_AF2122/97 LEMIVITMVGRPSGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHS
Rv2059|M.tuberculosis_H37Rv LEMIVITMVGRPSGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHS
MMAR_5071|M.marinum_M --------------------DVWGSVARAVAGGHLAVKSILTGAASDPHS
MUL_4147|M.ulcerans_Agy99 --------------------DVWGSVARAVAGGHLAVKSILTGAASDPHS
MLBr_00337|M.leprae_Br4923 --------------------DVWGSVARIIAGRHVAVTSIVTGAHTDPHT
MAV_0583|M.avium_104 --------------------DVWGSVARAVAGGHVAVASILSGSDQDPHS
TH_1746|M.thermoresistible__bu --------------------DVWGSVAATVAGDHVPVTSIISGPQHDPHS
MAB_0577c|M.abscessus_ATCC_199 --------------------DAWASVAQAVTGDHAKVSALVSGADTDPHS
Mflv_1454|M.gilvum_PYR-GCK -------------------VDQWGDIVSQLGGVCTRVTTVVAGSSVDPHD
Mvan_5320|M.vanbaalenii_PYR-1 -------------------VDQWGNIVSQLGGACAEVTTVLAGSAVDPHD
MSMEG_6047|M.smegmatis_MC2_155 -------------------VDQWGDIVSELGGACAKVTTVLAGSSVDPHD
* *..:. : * * ::::*. ***
Mb2085|M.bovis_AF2122/97 YQASPADAAAIVDAELVIYNGGGYDPWVDQVLAGHPGVQAVDAYSLLG--
Rv2059|M.tuberculosis_H37Rv YQASPADAAAIVDAELVIYNGGGYDPWVDQVLAGHPGVQAVDAYSLLG--
MMAR_5071|M.marinum_M YQASPVDAAMIADSSLLIYNGGGYDPWVDNVLANHPAINAIDAYSLLG--
MUL_4147|M.ulcerans_Agy99 YQASPVDAAMIADSSLLIYNGGGYDPWVDNVLANHPAINAIDAYPLLG--
MLBr_00337|M.leprae_Br4923 YRVNPAETAAITDAALVVYNGGGYDPWVDKVLAGRPDIKSVDAYSLLASR
MAV_0583|M.avium_104 YEASPSDAAAIADAGLVVFNGGGYDGWVDDVLAHHPGVARVDAYALLP--
TH_1746|M.thermoresistible__bu YEASPADAAALTDAALVVYNGGGYDRWATEVLAGRPDVRVVDAFALLP--
MAB_0577c|M.abscessus_ATCC_199 FEVTPAAAAQVQDATLVVYNGDGYDPFIDKLLKD--GEPRVNAYQLLP--
Mflv_1454|M.gilvum_PYR-GCK FEPAPSDAVAFEGAQLVVVNGGHYDEWATKLAQTSAPDAHLIDAVALSTG
Mvan_5320|M.vanbaalenii_PYR-1 YEPAPSDAADFEGAQLVVLNGGHYDEWAAKLAATSAADAPVVNAVELSGG
MSMEG_6047|M.smegmatis_MC2_155 FEPSPSDAAKFEGAQLVVINGGHYDEWAGKLARSSAPNAPVVAAVADAG-
:. * :. . .: *:: **. ** : .: :
Mb2085|M.bovis_AF2122/97 ---------------------------AVGDDDAPNEHVFYDPNVAKAVA
Rv2059|M.tuberculosis_H37Rv ---------------------------AVGDDDAPNEHVFYDPNVAKAVA
MMAR_5071|M.marinum_M ---------------------------TDAAR-PPDEHVFYNLHVAKSVA
MUL_4147|M.ulcerans_Agy99 ---------------------------TDAAR-PPDEHVFYNLHVAKSVA
MLBr_00337|M.leprae_Br4923 ---------------------------GATTEGPADEHVFYDLNIAKSVA
MAV_0583|M.avium_104 -----------------------------DAGRPRNEHVFYHLGVAKAVA
TH_1746|M.thermoresistible__bu -----------------------------ADEPATNEHVFYHLDVAAAVA
MAB_0577c|M.abscessus_ATCC_199 -----------------------------ADSADKNEHVFYSLRTAQQVA
Mflv_1454|M.gilvum_PYR-GCK HS--GHEDHGHEGHDH--EGHDHA--------DEGNPHVWYRPSAVTEVV
Mvan_5320|M.vanbaalenii_PYR-1 HAEQGQEHAGEDGHGHAEEGQEHAGEQGQELGDEGNPHVWYNPTAVTEFA
MSMEG_6047|M.smegmatis_MC2_155 ----AHEDDAHD-HGHDEHGHAHA-------EEGVNPHAWYSPAAVTTVA
: *.:* . ..
Mb2085|M.bovis_AF2122/97 ATIADRLADLDPSNSGNYRANAAEFSRGADAIAISEHAIATTYPDAAVIA
Rv2059|M.tuberculosis_H37Rv ATIADRLADLDPSNSGNYRANAAEFSRGADAIAISEHAIATTYPDAAVIA
MMAR_5071|M.marinum_M ATIAERLAIIDPAHAAEYRTNAVEFGRNADAIVDSERAIGAEHPAVGVIA
MUL_4147|M.ulcerans_Agy99 ATIAERLAIIDPAHAAEYRTNAVEFGRNADAIGDSERAIGAEHPAVGVIA
MLBr_00337|M.leprae_Br4923 SLIADQLVTIDPDNAADYQANATEFCRSADAIAISEHAIASDYPAAGVIV
MAV_0583|M.avium_104 AAVADRLAAIDPGNAADYRRNAAAFGRDADAIAGIEHTIAAAHPGGSVVA
TH_1746|M.thermoresistible__bu ENIAEELAEIDPEHADDFRANAAEFTRQAGEIAATARAVGEQHPDASVVS
MAB_0577c|M.abscessus_ATCC_199 NNVADDLAKADPGNADSYHANAKTFGQQLDSIASLQEDVATKYRGKAILA
Mflv_1454|M.gilvum_PYR-GCK DAVTAELTALSADAAGYFADRHRAFVESMKPYEDTVAAIRAGATGKTYAA
Mvan_5320|M.vanbaalenii_PYR-1 EAVTAQLGKLSPDAAGYFAERHAEFAESMKPYDEVIAAIKAGATGRTYAA
MSMEG_6047|M.smegmatis_MC2_155 DEVTAKLGDLAPEAKDYFAERRAAFTESMKPYNQLIDDIKAKASGKTYAA
:: * . : . * . :
Mb2085|M.bovis_AF2122/97 TEPVVHYLLAAAGLKNRTPATFIAANENGNDPTPADMAAVLDMIAGREVA
Rv2059|M.tuberculosis_H37Rv TEPVVHYLLAAAGLKNRTPATFIAANENGNDPTPADMAAVLDMIAGREVA
MMAR_5071|M.marinum_M TEPVVHYLLAASGLVNRTPAAFAQANENDSDPAPADLASVLTLIDRREVA
MUL_4147|M.ulcerans_Agy99 TEPVVHYLLAASGLVNRTPAAFAQANENDSDPAPADLASVLTLIDRREVA
MLBr_00337|M.leprae_Br4923 TEPVVHYLLQASGLVNRTPPAFTATHENENDPSAADMAAALNLINHRQVS
MAV_0583|M.avium_104 TEPVAFYLLEASGLVNRTPPALEAAVENETDPAPADLARALDLLDRRQVS
TH_1746|M.thermoresistible__bu TEPVAYYLLANAGISDRTPAGFAVAVEEGADPSPADVAAMLDLLESGEVS
MAB_0577c|M.abscessus_ATCC_199 TEPVASHLVSRCGLVDRTPHAFAEAAEQGQDPSPADVASALDLISTKQVA
Mflv_1454|M.gilvum_PYR-GCK AEGAFDDMAAALGLTNRTPPGFQVAAANHSEPSPADLDAFLNLLSERGVD
Mvan_5320|M.vanbaalenii_PYR-1 TESVFGDMATALGLVDRTPQGYQVAAANESDPSPADLDAFLQLLADRGVD
MSMEG_6047|M.smegmatis_MC2_155 TEAVFDDMAAAVGLTDRTPPGYQVASSNETDPSPADFDAFLTLLENRGVD
:* . : *: :*** : : :*:.**. * :: *
Mb2085|M.bovis_AF2122/97 ALLVNPQTPTAATDELQVAARRAGVPITELTETLPSGTDRDQFCAADRPD
Rv2059|M.tuberculosis_H37Rv ALLVNPQTPTAATDELQVAARRAGVPITELTETLPSGTDRDQFCAADRPD
MMAR_5071|M.marinum_M ALLVNPQTATATTAGLQAAAHRAGVPVAEVSETMPIDTDY----------
MUL_4147|M.ulcerans_Agy99 ALLVNPQTATATTAGLQAAAHRAGVPVAEVSETMPIDTDY----------
MLBr_00337|M.leprae_Br4923 ALLVNPQKSNAATNGLQAAARRSGVPVTEVTEMLPNDTDY----------
MAV_0583|M.avium_104 ALVVNPQTSASAVNGLREAARRAGVPVVEVRETLPDGADY----------
TH_1746|M.thermoresistible__bu ALLSNPQTETPATRQIEAAAERASVPVVSVTETLPADTDY----------
MAB_0577c|M.abscessus_ATCC_199 ALLFNPQTAGSVTNRIKQAAESHGVPVVTVTETLPEGTDY----------
Mflv_1454|M.gilvum_PYR-GCK VLVYNTQTEGSVPEQIRRAAEQSGVPVVEVTETLPSDAGS----------
Mvan_5320|M.vanbaalenii_PYR-1 VLIYNTQTEGSVPEQIRSAAEQAGIAVVDVTETLPSDAKS----------
MSMEG_6047|M.smegmatis_MC2_155 VLIYNVQTEGSVPQQLRTAAESAGIPVVEVTETVAPGADS----------
.*: * *. .. :. **. .:.:. : * :. .:
Mb2085|M.bovis_AF2122/97 RRGRSLRADHADRGLSARGHRVGDLLPTALVCHRRSGGRGRPRRASARPG
Rv2059|M.tuberculosis_H37Rv RRGRSLRADHADRGLSARGHRVGDLLPTALVCHRRSGGRGRPRRASARPG
MMAR_5071|M.marinum_M --------------LTWQRNTV-DQLAAALRSGR----------------
MUL_4147|M.ulcerans_Agy99 --------------LTWQRNTV-DQLAAALRSGR----------------
MLBr_00337|M.leprae_Br4923 --------------LTWQRNTI-DQLLTALQSNRSPR-------------
MAV_0583|M.avium_104 --------------LSWQRNTV-GQLQTALQPVRSLQP------------
TH_1746|M.thermoresistible__bu --------------LTWQRRTVEELAATLSRPAPAHR-------------
MAB_0577c|M.abscessus_ATCC_199 --------------VTWQRRTT-EQLAAALG-------------------
Mflv_1454|M.gilvum_PYR-GCK --------------FQDWQVAQLDSLAEALGVGT----------------
Mvan_5320|M.vanbaalenii_PYR-1 --------------FQDWQVAQLDSLAKALDVRT----------------
MSMEG_6047|M.smegmatis_MC2_155 --------------FEAWQVDQLTALAKALGVES----------------
.
Mb2085|M.bovis_AF2122/97 NCVRRTDGRGSRPGCPDRRGTPRDVFADHPRRGGRPGRGCPGRRDRDLGG
Rv2059|M.tuberculosis_H37Rv NCVRRTDGRGSRPGCPDRRGTPRDVFADHPRRGGRPGRGCPGRRDRDLGG
MMAR_5071|M.marinum_M --------------------------------------------------
MUL_4147|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00337|M.leprae_Br4923 --------------------------------------------------
MAV_0583|M.avium_104 --------------------------------------------------
TH_1746|M.thermoresistible__bu --------------------------------------------------
MAB_0577c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1454|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5320|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6047|M.smegmatis_MC2_155 --------------------------------------------------
Mb2085|M.bovis_AF2122/97 LRRGFRRRRHPAVAGAWSPGVGVRGHHLVCDLPDLLVAPAAPLTSRSRFR
Rv2059|M.tuberculosis_H37Rv LRRGFRRRRHPAVAGAWSPGVGVRGHHLVCDLPDLLVAPAAPLTSRSRFR
MMAR_5071|M.marinum_M --------------------------------------------------
MUL_4147|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00337|M.leprae_Br4923 --------------------------------------------------
MAV_0583|M.avium_104 --------------------------------------------------
TH_1746|M.thermoresistible__bu --------------------------------------------------
MAB_0577c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1454|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5320|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6047|M.smegmatis_MC2_155 --------------------------------------------------
Mb2085|M.bovis_AF2122/97 PL
Rv2059|M.tuberculosis_H37Rv PL
MMAR_5071|M.marinum_M --
MUL_4147|M.ulcerans_Agy99 --
MLBr_00337|M.leprae_Br4923 --
MAV_0583|M.avium_104 --
TH_1746|M.thermoresistible__bu --
MAB_0577c|M.abscessus_ATCC_199 --
Mflv_1454|M.gilvum_PYR-GCK --
Mvan_5320|M.vanbaalenii_PYR-1 --
MSMEG_6047|M.smegmatis_MC2_155 --