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VATPVILVTGHEGTAAVTADLLGLLTDHGTATLRSVAPGSVRRADPRPRCHRREQRRRHRASMKSAIHPD HHPRRLPRCPVLRRDQVVLEMIVITMVGRPSGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHSYQ ASPADAAAIVDAELVIYNGGGYDPWVDQVLAGHPGVQAVDAYSLLGAVGDDDAPNEHVFYDPNVAKAVAA TIADRLADLDPSNSGNYRANAAEFSRGADAIAISEHAIATTYPDAAVIATEPVVHYLLAAAGLKNRTPAT FIAANENGNDPTPADMAAVLDMIAGREVAALLVNPQTPTAATDELQVAARRAGVPITELTETLPSGTDRD QFCAADRPDRRGRSLRADHADRGLSARGHRVGDLLPTALVCHRRSGGRGRPRRASARPGNCVRRTDGRGS RPGCPDRRGTPRDVFADHPRRGGRPGRGCPGRRDRDLGGLRRGFRRRRHPAVAGAWSPGVGVRGHHLVCD LPDLLVAPAAPLTSRSRFRPL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2059 | - | - | 100% (511) | hypothetical protein Rv2059 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2085 | - | 0.0 | 100.00% (511) | hypothetical protein Mb2085 |
M. gilvum PYR-GCK | Mflv_1454 | - | 1e-30 | 31.10% (254) | periplasmic solute binding protein |
M. leprae Br4923 | MLBr_00337 | - | 9e-88 | 64.46% (242) | putative periplasmic solute-binding proteins |
M. abscessus ATCC 19977 | MAB_0577c | - | 6e-61 | 48.75% (240) | ABC transporter solute-binding protein |
M. marinum M | MMAR_5071 | - | 1e-88 | 64.64% (263) | hypothetical protein MMAR_5071 |
M. avium 104 | MAV_0583 | - | 2e-80 | 62.92% (240) | periplasmic solute binding protein family protein |
M. smegmatis MC2 155 | MSMEG_6047 | - | 3e-33 | 32.03% (256) | cation ABC transporter, periplasmic cation-binding protein, |
M. thermoresistible (build 8) | TH_1746 | - | 3e-77 | 58.33% (240) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_4147 | - | 3e-88 | 64.26% (263) | hypothetical protein MUL_4147 |
M. vanbaalenii PYR-1 | Mvan_5320 | - | 6e-32 | 31.20% (266) | periplasmic solute binding protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv2059|M.tuberculosis_H37Rv --------MATPVILVTGHEGTAAVTADLLGLLT--DHGTATLRSVAPG- Mb2085|M.bovis_AF2122/97 --------MATPVILVTGHEGTAAVTADLLGLLT--DHGTATLRSVAPG- MMAR_5071|M.marinum_M ------------MLRVRVAHGFSAILLSVLGATG--VAACGTDHDAHPG- MUL_4147|M.ulcerans_Agy99 -------------MRVRVAHGFSAILLSVLGATG--VAACGTDHDAHPG- MLBr_00337|M.leprae_Br4923 ------------------MRWLTTIILCLISSTV--AGGCGSLSSGHLR- MAV_0583|M.avium_104 --------MGTALTRDATRVGRTTRWLATVLAVTGWAALTGCTGPAHPH- TH_1746|M.thermoresistible__bu -----------------------------VSAVAFGSAACGQDRDVHQEH MAB_0577c|M.abscessus_ATCC_199 -----------------MPARVAGLAVAVATAGTLALSGCG-QSHERSG- Mflv_1454|M.gilvum_PYR-GCK MKTVIVCAMLRSTRRGRALAG-IAASAALVLTACGGSGNTGAGDEASAGD Mvan_5320|M.vanbaalenii_PYR-1 --------MISSFRGVRVLAATLAVSLPFVLSACGGD-DTSAMDTSAAPD MSMEG_6047|M.smegmatis_MC2_155 ---------------MRTLAVSVALAAPFALAACGSD---ESSTAEPAGD Rv2059|M.tuberculosis_H37Rv -SVRRADPRPRCHRREQRRRHRASMKSAIHPDHHPRRLPRCPVLRRDQVV Mb2085|M.bovis_AF2122/97 -SVRRADPRPRCHRREQRRRHRASMKSAIHPDHHPRRLPRCPVLRRDQVV MMAR_5071|M.marinum_M -AAAVVAST----------------------------------------- MUL_4147|M.ulcerans_Agy99 -AAAVVAST----------------------------------------- MLBr_00337|M.leprae_Br4923 -PTAVVAST----------------------------------------- MAV_0583|M.avium_104 -ATAVVAST----------------------------------------- TH_1746|M.thermoresistible__bu RAATVVAST----------------------------------------- MAB_0577c|M.abscessus_ATCC_199 -ALTVVAST----------------------------------------- Mflv_1454|M.gilvum_PYR-GCK CPAAPVDVVVS--------------------------------------- Mvan_5320|M.vanbaalenii_PYR-1 CPTTPVNVVVS--------------------------------------- MSMEG_6047|M.smegmatis_MC2_155 CPTTPVNVVVS--------------------------------------- . . Rv2059|M.tuberculosis_H37Rv LEMIVITMVGRPSGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHS Mb2085|M.bovis_AF2122/97 LEMIVITMVGRPSGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHS MMAR_5071|M.marinum_M --------------------DVWGSVARAVAGGHLAVKSILTGAASDPHS MUL_4147|M.ulcerans_Agy99 --------------------DVWGSVARAVAGGHLAVKSILTGAASDPHS MLBr_00337|M.leprae_Br4923 --------------------DVWGSVARIIAGRHVAVTSIVTGAHTDPHT MAV_0583|M.avium_104 --------------------DVWGSVARAVAGGHVAVASILSGSDQDPHS TH_1746|M.thermoresistible__bu --------------------DVWGSVAATVAGDHVPVTSIISGPQHDPHS MAB_0577c|M.abscessus_ATCC_199 --------------------DAWASVAQAVTGDHAKVSALVSGADTDPHS Mflv_1454|M.gilvum_PYR-GCK -------------------VDQWGDIVSQLGGVCTRVTTVVAGSSVDPHD Mvan_5320|M.vanbaalenii_PYR-1 -------------------VDQWGNIVSQLGGACAEVTTVLAGSAVDPHD MSMEG_6047|M.smegmatis_MC2_155 -------------------VDQWGDIVSELGGACAKVTTVLAGSSVDPHD * *..:. : * * ::::*. *** Rv2059|M.tuberculosis_H37Rv YQASPADAAAIVDAELVIYNGGGYDPWVDQVLAGHPGVQAVDAYSLLG-- Mb2085|M.bovis_AF2122/97 YQASPADAAAIVDAELVIYNGGGYDPWVDQVLAGHPGVQAVDAYSLLG-- MMAR_5071|M.marinum_M YQASPVDAAMIADSSLLIYNGGGYDPWVDNVLANHPAINAIDAYSLLG-- MUL_4147|M.ulcerans_Agy99 YQASPVDAAMIADSSLLIYNGGGYDPWVDNVLANHPAINAIDAYPLLG-- MLBr_00337|M.leprae_Br4923 YRVNPAETAAITDAALVVYNGGGYDPWVDKVLAGRPDIKSVDAYSLLASR MAV_0583|M.avium_104 YEASPSDAAAIADAGLVVFNGGGYDGWVDDVLAHHPGVARVDAYALLP-- TH_1746|M.thermoresistible__bu YEASPADAAALTDAALVVYNGGGYDRWATEVLAGRPDVRVVDAFALLP-- MAB_0577c|M.abscessus_ATCC_199 FEVTPAAAAQVQDATLVVYNGDGYDPFIDKLLKD--GEPRVNAYQLLP-- Mflv_1454|M.gilvum_PYR-GCK FEPAPSDAVAFEGAQLVVVNGGHYDEWATKLAQTSAPDAHLIDAVALSTG Mvan_5320|M.vanbaalenii_PYR-1 YEPAPSDAADFEGAQLVVLNGGHYDEWAAKLAATSAADAPVVNAVELSGG MSMEG_6047|M.smegmatis_MC2_155 FEPSPSDAAKFEGAQLVVINGGHYDEWAGKLARSSAPNAPVVAAVADAG- :. * :. . .: *:: **. ** : .: : Rv2059|M.tuberculosis_H37Rv ---------------------------AVGDDDAPNEHVFYDPNVAKAVA Mb2085|M.bovis_AF2122/97 ---------------------------AVGDDDAPNEHVFYDPNVAKAVA MMAR_5071|M.marinum_M ---------------------------TDAAR-PPDEHVFYNLHVAKSVA MUL_4147|M.ulcerans_Agy99 ---------------------------TDAAR-PPDEHVFYNLHVAKSVA MLBr_00337|M.leprae_Br4923 ---------------------------GATTEGPADEHVFYDLNIAKSVA MAV_0583|M.avium_104 -----------------------------DAGRPRNEHVFYHLGVAKAVA TH_1746|M.thermoresistible__bu -----------------------------ADEPATNEHVFYHLDVAAAVA MAB_0577c|M.abscessus_ATCC_199 -----------------------------ADSADKNEHVFYSLRTAQQVA Mflv_1454|M.gilvum_PYR-GCK HS--GHEDHGHEGHDH--EGHDHA--------DEGNPHVWYRPSAVTEVV Mvan_5320|M.vanbaalenii_PYR-1 HAEQGQEHAGEDGHGHAEEGQEHAGEQGQELGDEGNPHVWYNPTAVTEFA MSMEG_6047|M.smegmatis_MC2_155 ----AHEDDAHD-HGHDEHGHAHA-------EEGVNPHAWYSPAAVTTVA : *.:* . .. Rv2059|M.tuberculosis_H37Rv ATIADRLADLDPSNSGNYRANAAEFSRGADAIAISEHAIATTYPDAAVIA Mb2085|M.bovis_AF2122/97 ATIADRLADLDPSNSGNYRANAAEFSRGADAIAISEHAIATTYPDAAVIA MMAR_5071|M.marinum_M ATIAERLAIIDPAHAAEYRTNAVEFGRNADAIVDSERAIGAEHPAVGVIA MUL_4147|M.ulcerans_Agy99 ATIAERLAIIDPAHAAEYRTNAVEFGRNADAIGDSERAIGAEHPAVGVIA MLBr_00337|M.leprae_Br4923 SLIADQLVTIDPDNAADYQANATEFCRSADAIAISEHAIASDYPAAGVIV MAV_0583|M.avium_104 AAVADRLAAIDPGNAADYRRNAAAFGRDADAIAGIEHTIAAAHPGGSVVA TH_1746|M.thermoresistible__bu ENIAEELAEIDPEHADDFRANAAEFTRQAGEIAATARAVGEQHPDASVVS MAB_0577c|M.abscessus_ATCC_199 NNVADDLAKADPGNADSYHANAKTFGQQLDSIASLQEDVATKYRGKAILA Mflv_1454|M.gilvum_PYR-GCK DAVTAELTALSADAAGYFADRHRAFVESMKPYEDTVAAIRAGATGKTYAA Mvan_5320|M.vanbaalenii_PYR-1 EAVTAQLGKLSPDAAGYFAERHAEFAESMKPYDEVIAAIKAGATGRTYAA MSMEG_6047|M.smegmatis_MC2_155 DEVTAKLGDLAPEAKDYFAERRAAFTESMKPYNQLIDDIKAKASGKTYAA :: * . : . * . : Rv2059|M.tuberculosis_H37Rv TEPVVHYLLAAAGLKNRTPATFIAANENGNDPTPADMAAVLDMIAGREVA Mb2085|M.bovis_AF2122/97 TEPVVHYLLAAAGLKNRTPATFIAANENGNDPTPADMAAVLDMIAGREVA MMAR_5071|M.marinum_M TEPVVHYLLAASGLVNRTPAAFAQANENDSDPAPADLASVLTLIDRREVA MUL_4147|M.ulcerans_Agy99 TEPVVHYLLAASGLVNRTPAAFAQANENDSDPAPADLASVLTLIDRREVA MLBr_00337|M.leprae_Br4923 TEPVVHYLLQASGLVNRTPPAFTATHENENDPSAADMAAALNLINHRQVS MAV_0583|M.avium_104 TEPVAFYLLEASGLVNRTPPALEAAVENETDPAPADLARALDLLDRRQVS TH_1746|M.thermoresistible__bu TEPVAYYLLANAGISDRTPAGFAVAVEEGADPSPADVAAMLDLLESGEVS MAB_0577c|M.abscessus_ATCC_199 TEPVASHLVSRCGLVDRTPHAFAEAAEQGQDPSPADVASALDLISTKQVA Mflv_1454|M.gilvum_PYR-GCK AEGAFDDMAAALGLTNRTPPGFQVAAANHSEPSPADLDAFLNLLSERGVD Mvan_5320|M.vanbaalenii_PYR-1 TESVFGDMATALGLVDRTPQGYQVAAANESDPSPADLDAFLQLLADRGVD MSMEG_6047|M.smegmatis_MC2_155 TEAVFDDMAAAVGLTDRTPPGYQVASSNETDPSPADFDAFLTLLENRGVD :* . : *: :*** : : :*:.**. * :: * Rv2059|M.tuberculosis_H37Rv ALLVNPQTPTAATDELQVAARRAGVPITELTETLPSGTDRDQFCAADRPD Mb2085|M.bovis_AF2122/97 ALLVNPQTPTAATDELQVAARRAGVPITELTETLPSGTDRDQFCAADRPD MMAR_5071|M.marinum_M ALLVNPQTATATTAGLQAAAHRAGVPVAEVSETMPIDTDY---------- MUL_4147|M.ulcerans_Agy99 ALLVNPQTATATTAGLQAAAHRAGVPVAEVSETMPIDTDY---------- MLBr_00337|M.leprae_Br4923 ALLVNPQKSNAATNGLQAAARRSGVPVTEVTEMLPNDTDY---------- MAV_0583|M.avium_104 ALVVNPQTSASAVNGLREAARRAGVPVVEVRETLPDGADY---------- TH_1746|M.thermoresistible__bu ALLSNPQTETPATRQIEAAAERASVPVVSVTETLPADTDY---------- MAB_0577c|M.abscessus_ATCC_199 ALLFNPQTAGSVTNRIKQAAESHGVPVVTVTETLPEGTDY---------- Mflv_1454|M.gilvum_PYR-GCK VLVYNTQTEGSVPEQIRRAAEQSGVPVVEVTETLPSDAGS---------- Mvan_5320|M.vanbaalenii_PYR-1 VLIYNTQTEGSVPEQIRSAAEQAGIAVVDVTETLPSDAKS---------- MSMEG_6047|M.smegmatis_MC2_155 VLIYNVQTEGSVPQQLRTAAESAGIPVVEVTETVAPGADS---------- .*: * *. .. :. **. .:.:. : * :. .: Rv2059|M.tuberculosis_H37Rv RRGRSLRADHADRGLSARGHRVGDLLPTALVCHRRSGGRGRPRRASARPG Mb2085|M.bovis_AF2122/97 RRGRSLRADHADRGLSARGHRVGDLLPTALVCHRRSGGRGRPRRASARPG MMAR_5071|M.marinum_M --------------LTWQRNTV-DQLAAALRSGR---------------- MUL_4147|M.ulcerans_Agy99 --------------LTWQRNTV-DQLAAALRSGR---------------- MLBr_00337|M.leprae_Br4923 --------------LTWQRNTI-DQLLTALQSNRSPR------------- MAV_0583|M.avium_104 --------------LSWQRNTV-GQLQTALQPVRSLQP------------ TH_1746|M.thermoresistible__bu --------------LTWQRRTVEELAATLSRPAPAHR------------- MAB_0577c|M.abscessus_ATCC_199 --------------VTWQRRTT-EQLAAALG------------------- Mflv_1454|M.gilvum_PYR-GCK --------------FQDWQVAQLDSLAEALGVGT---------------- Mvan_5320|M.vanbaalenii_PYR-1 --------------FQDWQVAQLDSLAKALDVRT---------------- MSMEG_6047|M.smegmatis_MC2_155 --------------FEAWQVDQLTALAKALGVES---------------- . Rv2059|M.tuberculosis_H37Rv NCVRRTDGRGSRPGCPDRRGTPRDVFADHPRRGGRPGRGCPGRRDRDLGG Mb2085|M.bovis_AF2122/97 NCVRRTDGRGSRPGCPDRRGTPRDVFADHPRRGGRPGRGCPGRRDRDLGG MMAR_5071|M.marinum_M -------------------------------------------------- MUL_4147|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00337|M.leprae_Br4923 -------------------------------------------------- MAV_0583|M.avium_104 -------------------------------------------------- TH_1746|M.thermoresistible__bu -------------------------------------------------- MAB_0577c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_1454|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5320|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6047|M.smegmatis_MC2_155 -------------------------------------------------- Rv2059|M.tuberculosis_H37Rv LRRGFRRRRHPAVAGAWSPGVGVRGHHLVCDLPDLLVAPAAPLTSRSRFR Mb2085|M.bovis_AF2122/97 LRRGFRRRRHPAVAGAWSPGVGVRGHHLVCDLPDLLVAPAAPLTSRSRFR MMAR_5071|M.marinum_M -------------------------------------------------- MUL_4147|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00337|M.leprae_Br4923 -------------------------------------------------- MAV_0583|M.avium_104 -------------------------------------------------- TH_1746|M.thermoresistible__bu -------------------------------------------------- MAB_0577c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_1454|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5320|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6047|M.smegmatis_MC2_155 -------------------------------------------------- Rv2059|M.tuberculosis_H37Rv PL Mb2085|M.bovis_AF2122/97 PL MMAR_5071|M.marinum_M -- MUL_4147|M.ulcerans_Agy99 -- MLBr_00337|M.leprae_Br4923 -- MAV_0583|M.avium_104 -- TH_1746|M.thermoresistible__bu -- MAB_0577c|M.abscessus_ATCC_199 -- Mflv_1454|M.gilvum_PYR-GCK -- Mvan_5320|M.vanbaalenii_PYR-1 -- MSMEG_6047|M.smegmatis_MC2_155 --