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MKTVIVCAMLRSTRRGRALAGIAASAALVLTACGGSGNTGAGDEASAGDCPAAPVDVVVSVDQWGDIVSQ LGGVCTRVTTVVAGSSVDPHDFEPAPSDAVAFEGAQLVVVNGGHYDEWATKLAQTSAPDAHLIDAVALST GHSGHEDHGHEGHDHEGHDHADEGNPHVWYRPSAVTEVVDAVTAELTALSADAAGYFADRHRAFVESMKP YEDTVAAIRAGATGKTYAAAEGAFDDMAAALGLTNRTPPGFQVAAANHSEPSPADLDAFLNLLSERGVDV LVYNTQTEGSVPEQIRRAAEQSGVPVVEVTETLPSDAGSFQDWQVAQLDSLAEALGVGT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1454 | - | - | 100% (339) | periplasmic solute binding protein |
M. gilvum PYR-GCK | Mflv_3168 | - | 4e-07 | 22.46% (236) | periplasmic solute binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2085 | - | 6e-31 | 31.10% (254) | hypothetical protein Mb2085 |
M. tuberculosis H37Rv | Rv2059 | - | 6e-31 | 31.10% (254) | hypothetical protein Rv2059 |
M. leprae Br4923 | MLBr_00337 | - | 3e-36 | 32.46% (305) | putative periplasmic solute-binding proteins |
M. abscessus ATCC 19977 | MAB_0577c | - | 4e-35 | 31.69% (325) | ABC transporter solute-binding protein |
M. marinum M | MMAR_5071 | - | 3e-34 | 30.67% (313) | hypothetical protein MMAR_5071 |
M. avium 104 | MAV_0583 | - | 1e-37 | 34.56% (327) | periplasmic solute binding protein family protein |
M. smegmatis MC2 155 | MSMEG_6047 | - | 1e-114 | 63.58% (324) | cation ABC transporter, periplasmic cation-binding protein, |
M. thermoresistible (build 8) | TH_1746 | - | 2e-38 | 34.52% (281) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_4147 | - | 4e-34 | 30.67% (313) | hypothetical protein MUL_4147 |
M. vanbaalenii PYR-1 | Mvan_5320 | - | 1e-128 | 68.02% (344) | periplasmic solute binding protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb2085|M.bovis_AF2122/97 --------MATPVILVTGHEGTAAVTADLLGLLT--DHGTATLRSVAPG- Rv2059|M.tuberculosis_H37Rv --------MATPVILVTGHEGTAAVTADLLGLLT--DHGTATLRSVAPG- MMAR_5071|M.marinum_M ------------MLRVRVAHGFSAILLSVLGATG--VAACGTDHDAHPG- MUL_4147|M.ulcerans_Agy99 -------------MRVRVAHGFSAILLSVLGATG--VAACGTDHDAHPG- MLBr_00337|M.leprae_Br4923 ------------------MRWLTTIILCLISSTV--AGGCGSLSSGHLR- MAV_0583|M.avium_104 --------MGTALTRDATRVGRTTRWLATVLAVTGWAALTGCTGPAHPH- TH_1746|M.thermoresistible__bu -----------------------------VSAVAFGSAACGQDRDVHQEH MAB_0577c|M.abscessus_ATCC_199 -----------------MPARVAGLAVAVATAGTLALSGCG-QSHERSG- Mflv_1454|M.gilvum_PYR-GCK MKTVIVCAMLRSTRRGRALAG-IAASAALVLTACGGSGNTGAGDEASAGD Mvan_5320|M.vanbaalenii_PYR-1 --------MISSFRGVRVLAATLAVSLPFVLSACGGD-DTSAMDTSAAPD MSMEG_6047|M.smegmatis_MC2_155 ---------------MRTLAVSVALAAPFALAACGSD---ESSTAEPAGD Mb2085|M.bovis_AF2122/97 -SVRRADPRPRCHRREQRRRHRASMKSAIHPDHHPRRLPRCPVLRRDQVV Rv2059|M.tuberculosis_H37Rv -SVRRADPRPRCHRREQRRRHRASMKSAIHPDHHPRRLPRCPVLRRDQVV MMAR_5071|M.marinum_M -AAAVVAST----------------------------------------- MUL_4147|M.ulcerans_Agy99 -AAAVVAST----------------------------------------- MLBr_00337|M.leprae_Br4923 -PTAVVAST----------------------------------------- MAV_0583|M.avium_104 -ATAVVAST----------------------------------------- TH_1746|M.thermoresistible__bu RAATVVAST----------------------------------------- MAB_0577c|M.abscessus_ATCC_199 -ALTVVAST----------------------------------------- Mflv_1454|M.gilvum_PYR-GCK CPAAPVDVVVS--------------------------------------- Mvan_5320|M.vanbaalenii_PYR-1 CPTTPVNVVVS--------------------------------------- MSMEG_6047|M.smegmatis_MC2_155 CPTTPVNVVVS--------------------------------------- . . Mb2085|M.bovis_AF2122/97 LEMIVITMVGRPSGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHS Rv2059|M.tuberculosis_H37Rv LEMIVITMVGRPSGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHS MMAR_5071|M.marinum_M --------------------DVWGSVARAVAGGHLAVKSILTGAASDPHS MUL_4147|M.ulcerans_Agy99 --------------------DVWGSVARAVAGGHLAVKSILTGAASDPHS MLBr_00337|M.leprae_Br4923 --------------------DVWGSVARIIAGRHVAVTSIVTGAHTDPHT MAV_0583|M.avium_104 --------------------DVWGSVARAVAGGHVAVASILSGSDQDPHS TH_1746|M.thermoresistible__bu --------------------DVWGSVAATVAGDHVPVTSIISGPQHDPHS MAB_0577c|M.abscessus_ATCC_199 --------------------DAWASVAQAVTGDHAKVSALVSGADTDPHS Mflv_1454|M.gilvum_PYR-GCK -------------------VDQWGDIVSQLGGVCTRVTTVVAGSSVDPHD Mvan_5320|M.vanbaalenii_PYR-1 -------------------VDQWGNIVSQLGGACAEVTTVLAGSAVDPHD MSMEG_6047|M.smegmatis_MC2_155 -------------------VDQWGDIVSELGGACAKVTTVLAGSSVDPHD * *..:. : * * ::::*. *** Mb2085|M.bovis_AF2122/97 YQASPADAAAIVDAELVIYNGGGYDPWVDQVLAGHPGVQAVDAYSLLG-- Rv2059|M.tuberculosis_H37Rv YQASPADAAAIVDAELVIYNGGGYDPWVDQVLAGHPGVQAVDAYSLLG-- MMAR_5071|M.marinum_M YQASPVDAAMIADSSLLIYNGGGYDPWVDNVLANHPAINAIDAYSLLG-- MUL_4147|M.ulcerans_Agy99 YQASPVDAAMIADSSLLIYNGGGYDPWVDNVLANHPAINAIDAYPLLG-- MLBr_00337|M.leprae_Br4923 YRVNPAETAAITDAALVVYNGGGYDPWVDKVLAGRPDIKSVDAYSLLASR MAV_0583|M.avium_104 YEASPSDAAAIADAGLVVFNGGGYDGWVDDVLAHHPGVARVDAYALLP-- TH_1746|M.thermoresistible__bu YEASPADAAALTDAALVVYNGGGYDRWATEVLAGRPDVRVVDAFALLP-- MAB_0577c|M.abscessus_ATCC_199 FEVTPAAAAQVQDATLVVYNGDGYDPFIDKLLKD--GEPRVNAYQLLP-- Mflv_1454|M.gilvum_PYR-GCK FEPAPSDAVAFEGAQLVVVNGGHYDEWATKLAQTSAPDAHLIDAVALSTG Mvan_5320|M.vanbaalenii_PYR-1 YEPAPSDAADFEGAQLVVLNGGHYDEWAAKLAATSAADAPVVNAVELSGG MSMEG_6047|M.smegmatis_MC2_155 FEPSPSDAAKFEGAQLVVINGGHYDEWAGKLARSSAPNAPVVAAVADAG- :. * :. . .: *:: **. ** : .: : Mb2085|M.bovis_AF2122/97 ---------------------------AVGDDDAPNEHVFYDPNVAKAVA Rv2059|M.tuberculosis_H37Rv ---------------------------AVGDDDAPNEHVFYDPNVAKAVA MMAR_5071|M.marinum_M ---------------------------TDAAR-PPDEHVFYNLHVAKSVA MUL_4147|M.ulcerans_Agy99 ---------------------------TDAAR-PPDEHVFYNLHVAKSVA MLBr_00337|M.leprae_Br4923 ---------------------------GATTEGPADEHVFYDLNIAKSVA MAV_0583|M.avium_104 -----------------------------DAGRPRNEHVFYHLGVAKAVA TH_1746|M.thermoresistible__bu -----------------------------ADEPATNEHVFYHLDVAAAVA MAB_0577c|M.abscessus_ATCC_199 -----------------------------ADSADKNEHVFYSLRTAQQVA Mflv_1454|M.gilvum_PYR-GCK HS--GHEDHGHEGHDH--EGHDHA--------DEGNPHVWYRPSAVTEVV Mvan_5320|M.vanbaalenii_PYR-1 HAEQGQEHAGEDGHGHAEEGQEHAGEQGQELGDEGNPHVWYNPTAVTEFA MSMEG_6047|M.smegmatis_MC2_155 ----AHEDDAHD-HGHDEHGHAHA-------EEGVNPHAWYSPAAVTTVA : *.:* . .. Mb2085|M.bovis_AF2122/97 ATIADRLADLDPSNSGNYRANAAEFSRGADAIAISEHAIATTYPDAAVIA Rv2059|M.tuberculosis_H37Rv ATIADRLADLDPSNSGNYRANAAEFSRGADAIAISEHAIATTYPDAAVIA MMAR_5071|M.marinum_M ATIAERLAIIDPAHAAEYRTNAVEFGRNADAIVDSERAIGAEHPAVGVIA MUL_4147|M.ulcerans_Agy99 ATIAERLAIIDPAHAAEYRTNAVEFGRNADAIGDSERAIGAEHPAVGVIA MLBr_00337|M.leprae_Br4923 SLIADQLVTIDPDNAADYQANATEFCRSADAIAISEHAIASDYPAAGVIV MAV_0583|M.avium_104 AAVADRLAAIDPGNAADYRRNAAAFGRDADAIAGIEHTIAAAHPGGSVVA TH_1746|M.thermoresistible__bu ENIAEELAEIDPEHADDFRANAAEFTRQAGEIAATARAVGEQHPDASVVS MAB_0577c|M.abscessus_ATCC_199 NNVADDLAKADPGNADSYHANAKTFGQQLDSIASLQEDVATKYRGKAILA Mflv_1454|M.gilvum_PYR-GCK DAVTAELTALSADAAGYFADRHRAFVESMKPYEDTVAAIRAGATGKTYAA Mvan_5320|M.vanbaalenii_PYR-1 EAVTAQLGKLSPDAAGYFAERHAEFAESMKPYDEVIAAIKAGATGRTYAA MSMEG_6047|M.smegmatis_MC2_155 DEVTAKLGDLAPEAKDYFAERRAAFTESMKPYNQLIDDIKAKASGKTYAA :: * . : . * . : Mb2085|M.bovis_AF2122/97 TEPVVHYLLAAAGLKNRTPATFIAANENGNDPTPADMAAVLDMIAGREVA Rv2059|M.tuberculosis_H37Rv TEPVVHYLLAAAGLKNRTPATFIAANENGNDPTPADMAAVLDMIAGREVA MMAR_5071|M.marinum_M TEPVVHYLLAASGLVNRTPAAFAQANENDSDPAPADLASVLTLIDRREVA MUL_4147|M.ulcerans_Agy99 TEPVVHYLLAASGLVNRTPAAFAQANENDSDPAPADLASVLTLIDRREVA MLBr_00337|M.leprae_Br4923 TEPVVHYLLQASGLVNRTPPAFTATHENENDPSAADMAAALNLINHRQVS MAV_0583|M.avium_104 TEPVAFYLLEASGLVNRTPPALEAAVENETDPAPADLARALDLLDRRQVS TH_1746|M.thermoresistible__bu TEPVAYYLLANAGISDRTPAGFAVAVEEGADPSPADVAAMLDLLESGEVS MAB_0577c|M.abscessus_ATCC_199 TEPVASHLVSRCGLVDRTPHAFAEAAEQGQDPSPADVASALDLISTKQVA Mflv_1454|M.gilvum_PYR-GCK AEGAFDDMAAALGLTNRTPPGFQVAAANHSEPSPADLDAFLNLLSERGVD Mvan_5320|M.vanbaalenii_PYR-1 TESVFGDMATALGLVDRTPQGYQVAAANESDPSPADLDAFLQLLADRGVD MSMEG_6047|M.smegmatis_MC2_155 TEAVFDDMAAAVGLTDRTPPGYQVASSNETDPSPADFDAFLTLLENRGVD :* . : *: :*** : : :*:.**. * :: * Mb2085|M.bovis_AF2122/97 ALLVNPQTPTAATDELQVAARRAGVPITELTETLPSGTDRDQFCAADRPD Rv2059|M.tuberculosis_H37Rv ALLVNPQTPTAATDELQVAARRAGVPITELTETLPSGTDRDQFCAADRPD MMAR_5071|M.marinum_M ALLVNPQTATATTAGLQAAAHRAGVPVAEVSETMPIDTDY---------- MUL_4147|M.ulcerans_Agy99 ALLVNPQTATATTAGLQAAAHRAGVPVAEVSETMPIDTDY---------- MLBr_00337|M.leprae_Br4923 ALLVNPQKSNAATNGLQAAARRSGVPVTEVTEMLPNDTDY---------- MAV_0583|M.avium_104 ALVVNPQTSASAVNGLREAARRAGVPVVEVRETLPDGADY---------- TH_1746|M.thermoresistible__bu ALLSNPQTETPATRQIEAAAERASVPVVSVTETLPADTDY---------- MAB_0577c|M.abscessus_ATCC_199 ALLFNPQTAGSVTNRIKQAAESHGVPVVTVTETLPEGTDY---------- Mflv_1454|M.gilvum_PYR-GCK VLVYNTQTEGSVPEQIRRAAEQSGVPVVEVTETLPSDAGS---------- Mvan_5320|M.vanbaalenii_PYR-1 VLIYNTQTEGSVPEQIRSAAEQAGIAVVDVTETLPSDAKS---------- MSMEG_6047|M.smegmatis_MC2_155 VLIYNVQTEGSVPQQLRTAAESAGIPVVEVTETVAPGADS---------- .*: * *. .. :. **. .:.:. : * :. .: Mb2085|M.bovis_AF2122/97 RRGRSLRADHADRGLSARGHRVGDLLPTALVCHRRSGGRGRPRRASARPG Rv2059|M.tuberculosis_H37Rv RRGRSLRADHADRGLSARGHRVGDLLPTALVCHRRSGGRGRPRRASARPG MMAR_5071|M.marinum_M --------------LTWQRNTV-DQLAAALRSGR---------------- MUL_4147|M.ulcerans_Agy99 --------------LTWQRNTV-DQLAAALRSGR---------------- MLBr_00337|M.leprae_Br4923 --------------LTWQRNTI-DQLLTALQSNRSPR------------- MAV_0583|M.avium_104 --------------LSWQRNTV-GQLQTALQPVRSLQP------------ TH_1746|M.thermoresistible__bu --------------LTWQRRTVEELAATLSRPAPAHR------------- MAB_0577c|M.abscessus_ATCC_199 --------------VTWQRRTT-EQLAAALG------------------- Mflv_1454|M.gilvum_PYR-GCK --------------FQDWQVAQLDSLAEALGVGT---------------- Mvan_5320|M.vanbaalenii_PYR-1 --------------FQDWQVAQLDSLAKALDVRT---------------- MSMEG_6047|M.smegmatis_MC2_155 --------------FEAWQVDQLTALAKALGVES---------------- . Mb2085|M.bovis_AF2122/97 NCVRRTDGRGSRPGCPDRRGTPRDVFADHPRRGGRPGRGCPGRRDRDLGG Rv2059|M.tuberculosis_H37Rv NCVRRTDGRGSRPGCPDRRGTPRDVFADHPRRGGRPGRGCPGRRDRDLGG MMAR_5071|M.marinum_M -------------------------------------------------- MUL_4147|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00337|M.leprae_Br4923 -------------------------------------------------- MAV_0583|M.avium_104 -------------------------------------------------- TH_1746|M.thermoresistible__bu -------------------------------------------------- MAB_0577c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_1454|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5320|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6047|M.smegmatis_MC2_155 -------------------------------------------------- Mb2085|M.bovis_AF2122/97 LRRGFRRRRHPAVAGAWSPGVGVRGHHLVCDLPDLLVAPAAPLTSRSRFR Rv2059|M.tuberculosis_H37Rv LRRGFRRRRHPAVAGAWSPGVGVRGHHLVCDLPDLLVAPAAPLTSRSRFR MMAR_5071|M.marinum_M -------------------------------------------------- MUL_4147|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00337|M.leprae_Br4923 -------------------------------------------------- MAV_0583|M.avium_104 -------------------------------------------------- TH_1746|M.thermoresistible__bu -------------------------------------------------- MAB_0577c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_1454|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5320|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6047|M.smegmatis_MC2_155 -------------------------------------------------- Mb2085|M.bovis_AF2122/97 PL Rv2059|M.tuberculosis_H37Rv PL MMAR_5071|M.marinum_M -- MUL_4147|M.ulcerans_Agy99 -- MLBr_00337|M.leprae_Br4923 -- MAV_0583|M.avium_104 -- TH_1746|M.thermoresistible__bu -- MAB_0577c|M.abscessus_ATCC_199 -- Mflv_1454|M.gilvum_PYR-GCK -- Mvan_5320|M.vanbaalenii_PYR-1 -- MSMEG_6047|M.smegmatis_MC2_155 --