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TRRCIAACLAILLLAACGAPDGSDGRRQIVVTTTILGDVVSEVVGDTADVRVMMKPNADPHSYGLSAADA AEMARADLVIYNGLGLEESMQRHVDAAAENGVRTLPVGDHVDPLQFSADEHGAADPHFWTDPQRMILAVD AITGRVAELPGIDRAAVAANAARYRDELNNLSAHMTDRFAAIPAQRRKLVTNHHVLGYLADRFGFTVIGA VIPSGTTLASPSASDLESLAGAIRDAGVKAIFVDSSQPDRLARVLAEQSGVRVNVVSLYSESLSAPGTEA DSYLGMMRTNTETIANNLI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6050 | - | - | 100% (300) | solute-binding lipoprotein |
| M. smegmatis MC2 155 | MSMEG_6047 | - | 7e-14 | 26.80% (306) | cation ABC transporter, periplasmic cation-binding protein, |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2085 | - | 8e-11 | 24.47% (282) | hypothetical protein Mb2085 |
| M. gilvum PYR-GCK | Mflv_3168 | - | 3e-30 | 33.67% (297) | periplasmic solute binding protein |
| M. tuberculosis H37Rv | Rv2059 | - | 8e-11 | 24.47% (282) | hypothetical protein Rv2059 |
| M. leprae Br4923 | MLBr_00337 | - | 9e-07 | 22.06% (272) | putative periplasmic solute-binding proteins |
| M. abscessus ATCC 19977 | MAB_0577c | - | 7e-09 | 22.97% (296) | ABC transporter solute-binding protein |
| M. marinum M | MMAR_5071 | - | 7e-08 | 25.38% (264) | hypothetical protein MMAR_5071 |
| M. avium 104 | MAV_0583 | - | 2e-06 | 30.70% (114) | periplasmic solute binding protein family protein |
| M. thermoresistible (build 8) | TH_4096 | - | 2e-26 | 28.15% (302) | PUTATIVE periplasmic solute binding protein |
| M. ulcerans Agy99 | MUL_4147 | - | 8e-08 | 26.04% (265) | hypothetical protein MUL_4147 |
| M. vanbaalenii PYR-1 | Mvan_5324 | - | 1e-100 | 62.71% (295) | periplasmic solute binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00337|M.leprae_Br4923 --------------------------MRWLTTIILCLISSTVAG------
MAV_0583|M.avium_104 -----------MGTALTRDATRVGRTTRWLATVLAVTGWAALTG------
MMAR_5071|M.marinum_M --------------------MLRVRVAHGFSAILLSVLGATGVA------
MUL_4147|M.ulcerans_Agy99 ---------------------MRVRVAHGFSAILLSVLGATGVA------
Mb2085|M.bovis_AF2122/97 MATPVILVTGHEGTAAVTADLLGLLTDHGTATLRSVAPGSVRRADPRPRC
Rv2059|M.tuberculosis_H37Rv MATPVILVTGHEGTAAVTADLLGLLTDHGTATLRSVAPGSVRRADPRPRC
MAB_0577c|M.abscessus_ATCC_199 ----------------------MPARVAGLAVAVATAGTLALSG------
MSMEG_6050|M.smegmatis_MC2_155 ------------------------MTRRCIAACLAIL-LLAACG------
Mvan_5324|M.vanbaalenii_PYR-1 ------------------------MRRWTLVCICAILTAVAACT------
Mflv_3168|M.gilvum_PYR-GCK --------------MGARHASRRARGRPATWVAIACCASMVACS------
TH_4096|M.thermoresistible__bu ------------------MEIRRCLG--TVLAVWALVFGLLGCG------
MLBr_00337|M.leprae_Br4923 -------------GCGSLSSGHLR---------------PTAVVAST---
MAV_0583|M.avium_104 -------------CTG---PAHPH---------------ATAVVAST---
MMAR_5071|M.marinum_M -------------ACGTDHDAHPG---------------AAAVVAST---
MUL_4147|M.ulcerans_Agy99 -------------ACGTDHDAHPG---------------AAAVVAST---
Mb2085|M.bovis_AF2122/97 HRREQRRRHRASMKSAIHPDHHPRRLPRCPVLRRDQVVLEMIVITMVGRP
Rv2059|M.tuberculosis_H37Rv HRREQRRRHRASMKSAIHPDHHPRRLPRCPVLRRDQVVLEMIVITMVGRP
MAB_0577c|M.abscessus_ATCC_199 --------------CGQSHERSG----------------ALTVVAST---
MSMEG_6050|M.smegmatis_MC2_155 --------------APDGS--DGR---------------RQIVVTTT---
Mvan_5324|M.vanbaalenii_PYR-1 --------------GGTAA--SAT---------------GEVIVTTN---
Mflv_3168|M.gilvum_PYR-GCK --------------SPIDTGDAAR---------------PTVLTTFT---
TH_4096|M.thermoresistible__bu --------------PHRGAGDDT----------------PMVLTTFT---
: :
MLBr_00337|M.leprae_Br4923 --------DVWGSVARIIAGRHVAVTSIVTGAHTDPHTYRVNPAETAAIT
MAV_0583|M.avium_104 --------DVWGSVARAVAGGHVAVASILSGSDQDPHSYEASPSDAAAIA
MMAR_5071|M.marinum_M --------DVWGSVARAVAGGHLAVKSILTGAASDPHSYQASPVDAAMIA
MUL_4147|M.ulcerans_Agy99 --------DVWGSVARAVAGGHLAVKSILTGAASDPHSYQASPVDAAMIA
Mb2085|M.bovis_AF2122/97 SGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHSYQASPADAAAIV
Rv2059|M.tuberculosis_H37Rv SGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHSYQASPADAAAIV
MAB_0577c|M.abscessus_ATCC_199 --------DAWASVAQAVTGDHAKVSALVSGADTDPHSFEVTPAAAAQVQ
MSMEG_6050|M.smegmatis_MC2_155 ---------ILGDVVSEVVGDTADVRVMMKPN-ADPHSYGLSAADAAEMA
Mvan_5324|M.vanbaalenii_PYR-1 ---------ILGDVVRNVVGDAADVRVLMQPN-ADPHSFGVSAQDAAAMG
Mflv_3168|M.gilvum_PYR-GCK ---------VLADIAANVAGDHLTVESITKPG-AEIHGYEPTPGDIRKAA
TH_4096|M.thermoresistible__bu ---------VLADIARNVAGEHLQVESITKVG-AEIHGYEPTPGDIRKAA
..:. :.* * : : * : ..
MLBr_00337|M.leprae_Br4923 DAALVVYNGGGYDPWVDKVLAGR-----PDIKSVDAYSLLASRGATTEGP
MAV_0583|M.avium_104 DAGLVVFNGGGYDGWVDDVLAHH-----PGVARVDAYALLPDAGR----P
MMAR_5071|M.marinum_M DSSLLIYNGGGYDPWVDNVLANH-----PAINAIDAYSLLGTDAAR---P
MUL_4147|M.ulcerans_Agy99 DSSLLIYNGGGYDPWVDNVLANH-----PAINAIDAYPLLGTDAAR---P
Mb2085|M.bovis_AF2122/97 DAELVIYNGGGYDPWVDQVLAGH-----PGVQAVDAYSLLGAVGDDD--A
Rv2059|M.tuberculosis_H37Rv DAELVIYNGGGYDPWVDQVLAGH-----PGVQAVDAYSLLGAVGDDD--A
MAB_0577c|M.abscessus_ATCC_199 DATLVVYNGDGYDPFIDKLLKD-------GEPRVNAYQLLPADSAD----
MSMEG_6050|M.smegmatis_MC2_155 RADLVIYNGLGLEESMQRHVDAAAENGVRTLPVGDHVDPLQFS-ADEHGA
Mvan_5324|M.vanbaalenii_PYR-1 RAGLIVYNGLGLEETVIRNVESAAAEGVPTLAVTDHVDPIEFAEGDSAGT
Mflv_3168|M.gilvum_PYR-GCK RADLILDNGLNLEAWFARFVD---GIDVPHVVVSDGVAPLEIAEDAYTGM
TH_4096|M.thermoresistible__bu RADLILDNGLNLEAWFEQFIS---EVNVERVRVSDGIEPIGIAG---TDQ
: *:: ** . : . : : :
MLBr_00337|M.leprae_Br4923 ADEHVFYDLNIAKSVASLIADQLVTIDPDNAADYQANATEFCRSADAIAI
MAV_0583|M.avium_104 RNEHVFYHLGVAKAVAAAVADRLAAIDPGNAADYRRNAAAFGRDADAIAG
MMAR_5071|M.marinum_M PDEHVFYNLHVAKSVAATIAERLAIIDPAHAAEYRTNAVEFGRNADAIVD
MUL_4147|M.ulcerans_Agy99 PDEHVFYNLHVAKSVAATIAERLAIIDPAHAAEYRTNAVEFGRNADAIGD
Mb2085|M.bovis_AF2122/97 PNEHVFYDPNVAKAVAATIADRLADLDPSNSGNYRANAAEFSRGADAIAI
Rv2059|M.tuberculosis_H37Rv PNEHVFYDPNVAKAVAATIADRLADLDPSNSGNYRANAAEFSRGADAIAI
MAB_0577c|M.abscessus_ATCC_199 KNEHVFYSLRTAQQVANNVADDLAKADPGNADSYHANAKTFGQQLDSIAS
MSMEG_6050|M.smegmatis_MC2_155 ADPHFWTDPQRMILAVDAITGRVAELPGIDRAAVAANAARYRDELNNLSA
Mvan_5324|M.vanbaalenii_PYR-1 SDPHFWTDPQRMIMAVDAIEEAVREIDGIDRDAVARNAESYRAKLRELDT
Mflv_3168|M.gilvum_PYR-GCK ANPHAWMSPLNVQIYADNMADAFADLDPDHAQAYRDNAAAYRTQLQEVHD
TH_4096|M.thermoresistible__bu PNPHAWMSPLNVITYVDNMADAFSALDPANAEHYRANAEAYQQELRAVHE
: * : . : . . ** : :
MLBr_00337|M.leprae_Br4923 SEHAIASDYPA--AGVIVTEPVVHYLLQASGLVNRTPPAFTATHENENDP
MAV_0583|M.avium_104 IEHTIAAAHPG--GSVVATEPVAFYLLEASGLVNRTPPALEAAVENETDP
MMAR_5071|M.marinum_M SERAIGAEHPA--VGVIATEPVVHYLLAASGLVNRTPAAFAQANENDSDP
MUL_4147|M.ulcerans_Agy99 SERAIGAEHPA--VGVIATEPVVHYLLAASGLVNRTPAAFAQANENDSDP
Mb2085|M.bovis_AF2122/97 SEHAIATTYPD--AAVIATEPVVHYLLAAAGLKNRTPATFIAANENGNDP
Rv2059|M.tuberculosis_H37Rv SEHAIATTYPD--AAVIATEPVVHYLLAAAGLKNRTPATFIAANENGNDP
MAB_0577c|M.abscessus_ATCC_199 LQEDVATKYRG--KAILATEPVASHLVSRCGLVDRTPHAFAEAAEQGQDP
MSMEG_6050|M.smegmatis_MC2_155 HMTDRFAAIPAQRRKLVTNHHVLGYLADRFGFTVIG--AVIPSGTTLASP
Mvan_5324|M.vanbaalenii_PYR-1 SMRTGFDTIPAERRKLVTNHHVLGYLAQRFGFTVIG--AVVPSGTTLAAP
Mflv_3168|M.gilvum_PYR-GCK ELVERLDALPPTQRALVTCEGAFSYLARDAGLTEKY--IWAVNAEQQATP
TH_4096|M.thermoresistible__bu DLVNRLSGLPPGQRALVSCEGAFSYLARDAGLTEKY--IWPVNAEQQATP
:: . . :* *: *
MLBr_00337|M.leprae_Br4923 SAADMAAALNLINHRQVSALLVNPQKSNAATNGLQAAARRSGVPVTEVTE
MAV_0583|M.avium_104 APADLARALDLLDRRQVSALVVNPQTSASAVNGLREAARRAGVPVVEVRE
MMAR_5071|M.marinum_M APADLASVLTLIDRREVAALLVNPQTATATTAGLQAAAHRAGVPVAEVSE
MUL_4147|M.ulcerans_Agy99 APADLASVLTLIDRREVAALLVNPQTATATTAGLQAAAHRAGVPVAEVSE
Mb2085|M.bovis_AF2122/97 TPADMAAVLDMIAGREVAALLVNPQTPTAATDELQVAARRAGVPITELTE
Rv2059|M.tuberculosis_H37Rv TPADMAAVLDMIAGREVAALLVNPQTPTAATDELQVAARRAGVPITELTE
MAB_0577c|M.abscessus_ATCC_199 SPADVASALDLISTKQVAALLFNPQTAGSVTNRIKQAAESHGVPVVTVTE
MSMEG_6050|M.smegmatis_MC2_155 SASDLESLAGAIRDAGVKAIFVDSSQPDRLARVLAEQSGVRVNVVSLYSE
Mvan_5324|M.vanbaalenii_PYR-1 SASDLQSLVDAIDFARVPAIFVDSSQPDKLARVLARDAGVDVEIVPLYSE
Mflv_3168|M.gilvum_PYR-GCK --QQIASTIEFVDANDVPAVFCESTVSDAPMQRVVEATGTRFGGV-LFVD
TH_4096|M.thermoresistible__bu --RQIASVIEFVNANAVPAVFCESTVSDAPMQRVVEATGAVFGGV-LYVD
:: : * *:. :. . : : : :
MLBr_00337|M.leprae_Br4923 MLPNDTDY------------------------LTWQRNTIDQLL-TALQS
MAV_0583|M.avium_104 TLPDGADY------------------------LSWQRNTVGQLQ-TALQP
MMAR_5071|M.marinum_M TMPIDTDY------------------------LTWQRNTVDQLA-AALRS
MUL_4147|M.ulcerans_Agy99 TMPIDTDY------------------------LTWQRNTVDQLA-AALRS
Mb2085|M.bovis_AF2122/97 TLPSGTDRDQFCAADRPDRRGRSLRADHADRGLSARGHRVGDLLPTALVC
Rv2059|M.tuberculosis_H37Rv TLPSGTDRDQFCAADRPDRRGRSLRADHADRGLSARGHRVGDLLPTALVC
MAB_0577c|M.abscessus_ATCC_199 TLPEGTDY------------------------VTWQRRTTEQLA-AALG-
MSMEG_6050|M.smegmatis_MC2_155 SLSAPGTE--------------------ADSYLGMMRTNTETIANNLI--
Mvan_5324|M.vanbaalenii_PYR-1 SLSPPGTP--------------------GATYLDMMRANTDAIITGLR--
Mflv_3168|M.gilvum_PYR-GCK SLSEADGP--------------------VPTYLDLIRHDATTIAAALTAD
TH_4096|M.thermoresistible__bu SLSEPDGP--------------------VPTYLDLIRHDADVIAAGLAGR
:. : :
MLBr_00337|M.leprae_Br4923 NRSPR---------------------------------------------
MAV_0583|M.avium_104 VRSLQP--------------------------------------------
MMAR_5071|M.marinum_M GR------------------------------------------------
MUL_4147|M.ulcerans_Agy99 GR------------------------------------------------
Mb2085|M.bovis_AF2122/97 HRRSGGRGRPRRASARPGNCVRRTDGRGSRPGCPDRRGTPRDVFADHPRR
Rv2059|M.tuberculosis_H37Rv HRRSGGRGRPRRASARPGNCVRRTDGRGSRPGCPDRRGTPRDVFADHPRR
MAB_0577c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6050|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5324|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3168|M.gilvum_PYR-GCK RAS-----------------------------------------------
TH_4096|M.thermoresistible__bu RS------------------------------------------------
MLBr_00337|M.leprae_Br4923 --------------------------------------------------
MAV_0583|M.avium_104 --------------------------------------------------
MMAR_5071|M.marinum_M --------------------------------------------------
MUL_4147|M.ulcerans_Agy99 --------------------------------------------------
Mb2085|M.bovis_AF2122/97 GGRPGRGCPGRRDRDLGGLRRGFRRRRHPAVAGAWSPGVGVRGHHLVCDL
Rv2059|M.tuberculosis_H37Rv GGRPGRGCPGRRDRDLGGLRRGFRRRRHPAVAGAWSPGVGVRGHHLVCDL
MAB_0577c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6050|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5324|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3168|M.gilvum_PYR-GCK --------------------------------------------------
TH_4096|M.thermoresistible__bu --------------------------------------------------
MLBr_00337|M.leprae_Br4923 --------------------
MAV_0583|M.avium_104 --------------------
MMAR_5071|M.marinum_M --------------------
MUL_4147|M.ulcerans_Agy99 --------------------
Mb2085|M.bovis_AF2122/97 PDLLVAPAAPLTSRSRFRPL
Rv2059|M.tuberculosis_H37Rv PDLLVAPAAPLTSRSRFRPL
MAB_0577c|M.abscessus_ATCC_199 --------------------
MSMEG_6050|M.smegmatis_MC2_155 --------------------
Mvan_5324|M.vanbaalenii_PYR-1 --------------------
Mflv_3168|M.gilvum_PYR-GCK --------------------
TH_4096|M.thermoresistible__bu --------------------