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RMVVMGTGYLGATHAACMAELGHEVLGVDIDPAKLAKLEAGEVPFFEPGLSEVLRRHTSSGRLRFSSSYQ EAAEFADVFFVAVATPQKKGDYGADLCFVDAVIDNLAPLLDKPSLIIGKSTVPVGTATRLGRCVRDLAPA GDAVELVWNPEFLREGFAVQGTLHPDRLVLGVERPGSGRAEGIVREIYADLINDGVPFIVTDLATAELVK VSANAFLATKISFINAIAEVCEAVDADVTVLADAIGYDSRIGRRFLNAGLGFGGGCLPKDIRAFMARAGE LGANQALTFLREVDSINMRRRTRVVEIAREICGGGFIGSRVAVLGAAFKPDSDDVRDSPALNVAGQIQLQ GACVNVFDPQAMDNSRTLFPTLNYATSAFEACDGADVVLVLTEWEEFRSIDPAELKTTVRSAAVIDGRNC LDAAAWCAAGWYYRALGRPAAPRGANASVVTK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5982 | - | - | 100% (453) | UDP-glucose 6-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0680 | - | e-179 | 71.95% (435) | UDP-glucose 6-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5957 | algD | 2e-41 | 30.30% (439) | GDP-mannose 6-dehydrogenase AlgD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0330 | udgA | 1e-171 | 67.95% (440) | UDP-glucose 6-dehydrogenase UdgA |
| M. gilvum PYR-GCK | Mflv_0289 | - | 0.0 | 71.98% (439) | UDP-glucose 6-dehydrogenase |
| M. tuberculosis H37Rv | Rv0322 | udgA | 1e-171 | 67.95% (440) | UDP-glucose 6-dehydrogenase UdgA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4295c | - | 0.0 | 71.53% (439) | UDP-glucose 6-dehydrogenase (UdgA) |
| M. marinum M | MMAR_0603 | udgA | 1e-173 | 68.49% (438) | UDP-glucose dehydrogenase UdgA |
| M. avium 104 | MAV_4823 | - | 1e-173 | 68.81% (436) | UDP-glucose 6-dehydrogenase |
| M. thermoresistible (build 8) | TH_0768 | udgA | 1e-170 | 66.97% (439) | PROBABLE UDP-GLUCOSE 6-DEHYDROGENASE UDGA (UDP-GLC |
| M. ulcerans Agy99 | MUL_1511 | - | 5e-16 | 24.65% (361) | UDP-glucose 6-dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0598 | - | 0.0 | 72.67% (439) | UDP-glucose 6-dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0289|M.gilvum_PYR-GCK -------MRCTVFGTGYLGATHAAGMAELGHEVVGVDIDPGKVAKLAAGE
Mvan_0598|M.vanbaalenii_PYR-1 -------MRCTVFGTGYLGATHAAGMAELGHDVLGVDIDAGKVAKLSGGE
TH_0768|M.thermoresistible__bu -------MRCTVFGAGYLGTTHAAGMAALGHEVIAVDVDAGKVAKLAAGE
Mb0330|M.bovis_AF2122/97 -------MRCSVFGTGYLGATHAVGMAQLGHEVVGVDIDPGKVAKLAGGD
Rv0322|M.tuberculosis_H37Rv -------MRCSVFGTGYLGATHAVGMAQLGHEVVGVDIDPGKVAKLAGGD
MMAR_0603|M.marinum_M -------MRCTVFGTGYLGATHAVGMAQLGHEVVGVDIDPGKVAKLAGGD
MAV_4823|M.avium_104 -----------MFGTGYLGATHAVGMAELGHDVLGVDIDPGKVAKLAGGD
MAB_4295c|M.abscessus_ATCC_199 -------MRCTVFGTGYLGATHAACMAELGHEVLGVDIDPGKVAKLSSGD
MSMEG_5982|M.smegmatis_MC2_155 -------MRMVVMGTGYLGATHAACMAELGHEVLGVDIDPAKLAKLEAGE
MUL_1511|M.ulcerans_Agy99 MTTQPSERICIVGGAGHVGLPLALVLADEGYNVDILDTNAEALETIMAGR
: *:*::* . * :* *::* :* :. : .: .*
Mflv_0289|M.gilvum_PYR-GCK VPFYEPGLREALQRNIEAGRLRFTTDYAEAAEFADVHFLGVGTPQKKGEY
Mvan_0598|M.vanbaalenii_PYR-1 VPFYEPGLREMLRRNIDAGRLRFTTDYAEAAGFADVHFLGVGTPQKKGEY
TH_0768|M.thermoresistible__bu VPFYEPGLRALVTENLATGRLQFTTDYDAAADFADLHFLGVGTPQQRGDY
Mb0330|M.bovis_AF2122/97 IPFYEPGLRKLLTDNLAAGRLRFTTDYDMAADFADVHFLGVGTPQKIGEY
Rv0322|M.tuberculosis_H37Rv IPFYEPGLRKLLTDNLAAGRLRFTTDYDMAADFADVHFLGVGTPQKIGEY
MMAR_0603|M.marinum_M IPFYEPGLRKLLRDNLAAGRLHFTTDYDMAAEFADVHFLGVGTPQKRGEY
MAV_4823|M.avium_104 IPFYEPGLRKLLNENLAAGRLRFTTDYDMAAGFADVHFLGVGTPQKKGEY
MAB_4295c|M.abscessus_ATCC_199 IPFYEPGLRKILQSNIASGRLRFTTSYAEAAEFADVHFLGVGTPQKKGEY
MSMEG_5982|M.smegmatis_MC2_155 VPFFEPGLSEVLRRHTSSGRLRFSSSYQEAAEFADVFFVAVATPQKKGDY
MUL_1511|M.ulcerans_Agy99 MPFIETGAEDLLKPLLPTGRISGSTDSQVVRN-SDIVICVVGTP-VDEYL
:** *.* : :**: ::. . :*: : *.**
Mflv_0289|M.gilvum_PYR-GCK AADLRHVYAVIDTLVPLLRRPAVIVGKSTVPVGTAAELVERAAGLAPDGV
Mvan_0598|M.vanbaalenii_PYR-1 GADLRHVYAVIDTLVPLLTRPAVIVGKSTVPVGTAADLSERAAGLAPEGV
TH_0768|M.thermoresistible__bu SADLTQVHAVVDTLVPRLRRPAVIVGKSTVPVGTARDLLERARRLAPTGV
Mb0330|M.bovis_AF2122/97 GADLRHVHAVIDALVPRLVRASILVGKSTVPVGTAAELGHRAGALAPRGV
Rv0322|M.tuberculosis_H37Rv GADLRHVHAVIDALVPRLVRASILVGKSTVPVGTAAELGHRAGALAPRGV
MMAR_0603|M.marinum_M GADLRHIHAVIDTLVPRLTRTSVLIGKSTVPVGTAAELARRAAGLAVAGV
MAV_4823|M.avium_104 GADLRHVYAVIDELVPRLTTSAVLVGKSTVPVGTAAELNQRAAALAPRGV
MAB_4295c|M.abscessus_ATCC_199 GADLRHVHSVIDTLVPLLSRSAVIIGKSTVPVGTARELGQRAAGFAAAGV
MSMEG_5982|M.smegmatis_MC2_155 GADLCFVDAVIDNLAPLLDKPSLIIGKSTVPVGTATRLGRCVRDLAPAGD
MUL_1511|M.ulcerans_Agy99 TPQAHTFFRVIDEISPYFHDGQTLILRSTVYPGLSQRVHD---MFSERGI
.: . *:* : * : :: :*** * : : :: *
Mflv_0289|M.gilvum_PYR-GCK TVEVAWNPEFLREGFAVQDTLHPDRIVLGVQK-DSRIAEPVLRELYAALL
Mvan_0598|M.vanbaalenii_PYR-1 TVEVAWNPEFLREGFAVADTLHPDRIVLGVQR-DSQLAEPVLREMYAPLL
TH_0768|M.thermoresistible__bu DVEVAWNPEFLREGFAVRDTLHPDRIVVGAPP-DSVRAEPMLRELYAPLL
Mb0330|M.bovis_AF2122/97 DVEIAWNPEFLREGFAVHDTLNPDRIVLGVQD-DSTRAEVAVRELYAPLL
Rv0322|M.tuberculosis_H37Rv DVEIAWNPEFLREGFAVHDTLNPDRIVLGVQD-DSTRAEVAVRELYAPLL
MMAR_0603|M.marinum_M GVEIAWNPEFLREGFAVRDTLRPDRIVLGVQE-DSILAEQFVRELYGPLL
MAV_4823|M.avium_104 NVEIAWNPEFLREGYAVQDTLRPDRIVLGIKQ-DSPRAEAAVRELYGPLL
MAB_4295c|M.abscessus_ATCC_199 DVEVAWNPEFLREGYAVKDTLHPDRIVLGVQR-DSDRAEKLVRELYGPIL
MSMEG_5982|M.smegmatis_MC2_155 AVELVWNPEFLREGFAVQGTLHPDRLVLGVERPGSGRAEGIVREIYADLI
MUL_1511|M.ulcerans_Agy99 GVHVTFCPERIAQGHSIRELRIIPQIISGFDA----EGLRVVRELFSGIA
*.:.: ** : :*.:: ::: * . :**::. :
Mflv_0289|M.gilvum_PYR-GCK ADGAPFLVSDLQTAELAKVSANAFLATKISFINAISEVCEAVGADVTLLA
Mvan_0598|M.vanbaalenii_PYR-1 AAGVPFLIADLQTAELVKVSANAFLATKISFINAISEVCEAVDADVTLLA
TH_0768|M.thermoresistible__bu GDGVPWLSTDLQTAELVKVSANAFLATKISFINAISDVCEAVGADVVTLA
Mb0330|M.bovis_AF2122/97 AAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCEAAGADVSQLA
Rv0322|M.tuberculosis_H37Rv AAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCEAAGADVSQLA
MMAR_0603|M.marinum_M EAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCEAAGADVSLLA
MAV_4823|M.avium_104 DAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCEAAGADVSLLA
MAB_4295c|M.abscessus_ATCC_199 DEEVPFLVTDLETAELVKVSANAFLATKISFINAISEVCEAVGADVTTLA
MSMEG_5982|M.smegmatis_MC2_155 NDGVPFIVTDLATAELVKVSANAFLATKISFINAIAEVCEAVDADVTVLA
MUL_1511|M.ulcerans_Agy99 SE---IIKVEPQEAELAKLFCNSYRYIQFAVANQFYLLSREAGQDFDRVH
: : ***.*: .*:: :::. * : :.. .. *. :
Mflv_0289|M.gilvum_PYR-GCK DALGHDARIGRRFLNAGLGFGGGCLPKDIRAFMARAGELGANQALTFLRE
Mvan_0598|M.vanbaalenii_PYR-1 DALGHDARIGRRFLNAGLGFGGGCLPKDIRAFMARAGELGANHALTFLRE
TH_0768|M.thermoresistible__bu DALGHDPRIGRRFLNAGLGFGGGCLPKDIRAFMARAGELGANHTLTLLRE
Mb0330|M.bovis_AF2122/97 DALGYDPRIGRQCLNAGLGFGGGCLPKDIRAFMARAGELGADQALTFLRE
Rv0322|M.tuberculosis_H37Rv DALGYDPRIGRQCLNAGLGFGGGCLPKDIRAFMARAGELGADQALTFLRE
MMAR_0603|M.marinum_M DALGYDTRIGRQCLNAGLGFGGGCLPKDIRAFMARAGELGANQALTFLRE
MAV_4823|M.avium_104 DALGYDPRIGRQFLNAGLGFGGGCLPKDIRAFMARAGELGADQALTFLRE
MAB_4295c|M.abscessus_ATCC_199 DALGYDPRIGRRFLNAGLGFGGGCLPKDIRAFMARAGELGASHALTFLRE
MSMEG_5982|M.smegmatis_MC2_155 DAIGYDSRIGRRFLNAGLGFGGGCLPKDIRAFMARAGELGANQALTFLRE
MUL_1511|M.ulcerans_Agy99 HATTYKNSRVDSLPRAGLAAG-PCLLKDTMQLAAFS-----NNNFMLGHS
.* :. .***. * ** ** : * : .: : : :.
Mflv_0289|M.gilvum_PYR-GCK VDSINMRRRTRMVELATTACGGSLLGANIAVLGAAFKPESDDVRDSPALN
Mvan_0598|M.vanbaalenii_PYR-1 VDSINMRRRTRMVELATKACGGSLLGANVAVLGAAFKPESDDVRDSPALN
TH_0768|M.thermoresistible__bu VDSINMRRRARMVELATTACGGSLLGANIAVLGAAFKPDSDDVRDSPALN
Mb0330|M.bovis_AF2122/97 VDSINMRRRTKMVELATTACGGSLLGANIAVLGAAFKPESDDVRDSPALN
Rv0322|M.tuberculosis_H37Rv VDSINMRRRTKMVELATTACGGSLLGANIAVLGAAFKPESDDVRDSPALN
MMAR_0603|M.marinum_M VDSINMRRRTRMVELATTACGGSLLGANLAVLGAAFKPESDDVRDSPALN
MAV_4823|M.avium_104 VDSINMRRRTRMVELASAACGGSLLGANVAVLGAAFKPESDDVRDSPALN
MAB_4295c|M.abscessus_ATCC_199 VDSINMRRRTRMVELATKACGGSLLGANVAVLGAAFKPESDDVRDSPALN
MSMEG_5982|M.smegmatis_MC2_155 VDSINMRRRTRVVEIAREICGGGFIGSRVAVLGAAFKPDSDDVRDSPALN
MUL_1511|M.ulcerans_Agy99 AMLINEGQPQFIVNMLKRRVN--LRDKTVGILGMTFKADCDDTRDSLSFK
. ** : :*:: . : . :.:** :**.:.**.*** :::
Mflv_0289|M.gilvum_PYR-GCK VAGMLQLHGATVNVYDPKAMDNSRRLFPTLNYSASALDACERADAVLVLT
Mvan_0598|M.vanbaalenii_PYR-1 VAGMLQLNGATVNVYDPQAIENSRRLFPTLNYATTVVEACDRADAVLVLT
TH_0768|M.thermoresistible__bu VAGMLQLNGATVTVYDPKAMENSRRVFPTLTYSTSVAEACDRADAVLVLT
Mb0330|M.bovis_AF2122/97 VAGQLQLNGATVHVYDPKALDNAHRLFPTLNYAVSVAEACERADAVLVLT
Rv0322|M.tuberculosis_H37Rv VAGQLQLNGATVHVYDPKALDNAHRLFPTLNYAVSVAEACERADAVLVLT
MMAR_0603|M.marinum_M VAGQLQLNGAAVNVYDPKALDNANRLFPTLNYAVSVAEACERADAVLILT
MAV_4823|M.avium_104 VAGQLQLNGAAVNVYDPKALDNAQRLFPTLNYAVSVEEACERADAVLVLT
MAB_4295c|M.abscessus_ATCC_199 VAGLLQLNGAAVNVYDPKALENSRRLFPTLNYATSVLEAADRADAVLLLT
MSMEG_5982|M.smegmatis_MC2_155 VAGQIQLQGACVNVFDPQAMDNSRTLFPTLNYATSAFEACDGADVVLVLT
MUL_1511|M.ulcerans_Agy99 LRHLLMLEAKEVILHDPFLEGKDYHPLQTV---------VDRSDVIVVGV
: : *.. * :.** : : *: : :*.::: .
Mflv_0289|M.gilvum_PYR-GCK EWSEFVGMHPDELSAAVRTKVIVDGRNCLDIGVWRDAGWQVHALGRTVEV
Mvan_0598|M.vanbaalenii_PYR-1 EWREFVELDPVLLADTVRAKVVVDGRNCLDVGRWQQAGWQVFALGRFGGE
TH_0768|M.thermoresistible__bu EWQEFIDLNPAELADIVRAKVIVDGRNCLDVRRWQRAGWKVFCLGRTP--
Mb0330|M.bovis_AF2122/97 EWREFIDLEPADLANRVRARVIVDGRNCLDVTRWRRAGWRVFRLG--VPR
Rv0322|M.tuberculosis_H37Rv EWREFIDLEPADLANRVRARVIVDGRNCLDVTRWRRAGWRVFRLG--VPR
MMAR_0603|M.marinum_M EWQEFVDLDPDDLADRVRARVIVDGRNCLDVSRWERAGWRVFRLG--ARI
MAV_4823|M.avium_104 EWRQFVEMDPDDLADRVRARVVVDGRNCLDVTRWQRAGWRVYRLG--APR
MAB_4295c|M.abscessus_ATCC_199 EWQEFVDFDPDALAKVVRTKVIVDGRNCLDAAKWVNAGWRVFCLGKRVEE
MSMEG_5982|M.smegmatis_MC2_155 EWEEFRSIDPAELKTTVRSAAVIDGRNCLDAAAWCAAGWYYRALGRPAAP
MUL_1511|M.ulcerans_Agy99 PHSAYRGLR------VPRGKVVEDVWGCLDVTEFDVDPCNGANLAELGTA
: : * .: * .*** : *.
Mflv_0289|M.gilvum_PYR-GCK GA--------
Mvan_0598|M.vanbaalenii_PYR-1 PAAA------
TH_0768|M.thermoresistible__bu ----------
Mb0330|M.bovis_AF2122/97 LGH-------
Rv0322|M.tuberculosis_H37Rv LGH-------
MMAR_0603|M.marinum_M RAAS------
MAV_4823|M.avium_104 P---------
MAB_4295c|M.abscessus_ATCC_199 LAHT------
MSMEG_5982|M.smegmatis_MC2_155 RGANASVVTK
MUL_1511|M.ulcerans_Agy99 AAR-------