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M. smegmatis MC2 155 MSMEG_5734 (-)

annotation: alpha-methylacyl-CoA racemase
coordinates: 5817499 - 5818581
length: 360

TKTGPLSGVRVVELGGIGPGPHAAMMLSDLGADVVRVRRPGGLTLPAENVDLLHRGKRIVDLDVKAEPAK
LLDLVAKADVLLDCFRPGTCERLGIGPKECEAVNPRLIFARITGWGQDGPLAQTAGHDINYLSQTGALSA
IGYRDRPPVAPMNLVADFGGGSMLVLVGIVSALYERERSGKGQVIDAAMVDGVSMLAQMMWTMRATGSLR
DERESFLLDGGAPFYRCYETADGGYMAVGSIEPQFFAQLVAGLGLAADEIPGQFEIGRYDEMRKIFTERF
KTKTRAEWTEIFAGTDACVTPVLTWGEAAENAHLRERSTLIDVDGVAQAAPAPRFSRTPAPTPGKPPQGS
TSIEDIGWD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5734--100% (360)alpha-methylacyl-CoA racemase
M. smegmatis MC2 155MSMEG_5184-e-11557.30% (356) alpha-methylacyl-CoA racemase, putative
M. smegmatis MC2 155MSMEG_4111-4e-5032.33% (331) alpha-methylacyl-CoA racemase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0878far1e-16274.93% (359) fatty-acid-CoA racemase
M. gilvum PYR-GCKMflv_2126-1e-10654.47% (347) L-carnitine dehydratase/bile acid-inducible protein F
M. tuberculosis H37RvRv0855far1e-16274.93% (359) fatty-acid-CoA racemase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0845-1e-15673.11% (357) fatty-acid-CoA racemase Far
M. marinum MMMAR_4681far1e-16477.46% (355) fatty-acid-CoA racemase Far
M. avium 104MAV_0976-1e-16176.06% (355) alpha-methylacyl-CoA racemase
M. thermoresistible (build 8)TH_4477-1e-11356.62% (355) PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F
M. ulcerans Agy99MUL_0986mcr1e-10955.34% (365) alpha-methylacyl-CoA racemase Mcr
M. vanbaalenii PYR-1Mvan_4578-1e-11258.05% (348) L-carnitine dehydratase/bile acid-inducible protein F

CLUSTAL 2.0.9 multiple sequence alignment


Mb0878|M.bovis_AF2122/97            MTTG----GPLAGVKVIELGGIGPGPHAGMVLADLGADVVRVRRPG---G
Rv0855|M.tuberculosis_H37Rv         MTTG----GPLAGVKVIELGGIGPGPHAGMVLADLGADVVRVRRPG---G
MMAR_4681|M.marinum_M               MAGG----GPLAGVKVIELGGIGPGPHAGMVLADLGADVVRVRRPG---G
MAV_0976|M.avium_104                MSSG----GPLAGVRVIELGGIGPGPHAGMVLADLGADVVRVRRPG---V
MSMEG_5734|M.smegmatis_MC2_155      MTKT----GPLSGVRVVELGGIGPGPHAAMMLSDLGADVVRVRRPG---G
MAB_0845|M.abscessus_ATCC_1997      MADTGVKTGPLAGVKVIELGGIGPGPHAAMMLSDLGADVIRVRRPG---G
Mflv_2126|M.gilvum_PYR-GCK          MAG------PLQGLRVVELAGIGPGPHAAMIFGDLGADVVRIERPGKGPG
Mvan_4578|M.vanbaalenii_PYR-1       MAG------PLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPGKGPG
TH_4477|M.thermoresistible__bu      MAG------PLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPRNTPG
MUL_0986|M.ulcerans_Agy99           MSG------PLNGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSSAG
                                    *:       ** *::*:**.********.*::.******:*: **     

Mb0878|M.bovis_AF2122/97            LTMPSEDRDLLHRGKRIVDLDVKTQP--QAMLELAAKADVLLDCFRPGTC
Rv0855|M.tuberculosis_H37Rv         LTMPSEDRDLLHRGKRIVDLDVKTQP--QAMLELAAKADVLLDCFRPGTC
MMAR_4681|M.marinum_M               LQMPAEDRDLLHRGKRIVDLDVKSQP--QALLELAAKADVLLDCFRPGTC
MAV_0976|M.avium_104                AAMPSEDRDLLHRGKRIVDLDVKARP--QALLDLAAKADVLLDCFRPGTC
MSMEG_5734|M.smegmatis_MC2_155      LTLPAENVDLLHRGKRIVDLDVKAEP--AKLLDLVAKADVLLDCFRPGTC
MAB_0845|M.abscessus_ATCC_1997      LAIPAEETDLFHRGKRLVNLDVKKDP--EALLALVDKADVLLDPFRPGVC
Mflv_2126|M.gilvum_PYR-GCK          PATKPGG-DYLLRNRRSVAANLKSDEDREMVLRLIAKADVLIEGFRPGVT
Mvan_4578|M.vanbaalenii_PYR-1       PATKPGG-DYLLRNRRSVAANLKSEEDRDMVLRLIAKADVLIEGFRPGVT
TH_4477|M.thermoresistible__bu      PGIPRGAKDHLLRNRRSVAADLKTEEGKELVRKLIAKADVLIEGYRPGVT
MUL_0986|M.ulcerans_Agy99           -GRGGGVKDAMLRNRRIVTADLKSDQGRELVLKLVAKADVLIEGYRPGVT
                                            * : *.:* *  ::*       :  *  *****:: :***. 

Mb0878|M.bovis_AF2122/97            ERLGIGPDDCASVNPRLIFARITGWGQDGPLASTAGHDINYLSQTGALAA
Rv0855|M.tuberculosis_H37Rv         ERLGIGPDDCASVNPRLIFARITGWGQDGPLASTAGHDINYLSQTGALAA
MMAR_4681|M.marinum_M               ERLGIGPDDCAAVNPRLIFARITGWGQDGPLAPTAGHDINYLSQTGALSA
MAV_0976|M.avium_104                ERLGIGPDDCAAVNPRLIFARITGWGQHGPLAQTAGHDINYLSQTGVLSA
MSMEG_5734|M.smegmatis_MC2_155      ERLGIGPKECEAVNPRLIFARITGWGQDGPLAQTAGHDINYLSQTGALSA
MAB_0845|M.abscessus_ATCC_1997      ERIGIGPEECAKRNPRLIFARMTGWGQHGPMADRAGHDINYLSLTGALGS
Mflv_2126|M.gilvum_PYR-GCK          ERLGLGPEDCAKVNEKLVYARMTGWGQDGPRAQQAGHDINYISLNGVLHA
Mvan_4578|M.vanbaalenii_PYR-1       ERLGLGPHDCAKVNEKLIYARMTGWGQDGPRAQQAGHDINYISLNGALHA
TH_4477|M.thermoresistible__bu      ERLGLGPEDCAKINPRLIYGRMTGWGQDGPRAQQAGHDINYISLNGTLHA
MUL_0986|M.ulcerans_Agy99           ERLGLGPQDCAKVNDRLIYARMTGWGQAGPRSQQAGHDINYISLNGILHA
                                    **:*:**.:*   * :*::.*:***** ** :  *******:* .* * :

Mb0878|M.bovis_AF2122/97            FGYADRPPMPPLNLVADFGGGSMLVLLGIVVALYERERSGVGQVVDAAMV
Rv0855|M.tuberculosis_H37Rv         FGYADRPPMPPLNLVADFGGGSMLVLLGIVVALYERERSGVGQVVDAAMV
MMAR_4681|M.marinum_M               LGYRDRPPTPPLNLVADFGGGSMLVLLGIMAALYERERSGQGQVIDAAMV
MAV_0976|M.avium_104                LGHADRPPLPPLNLVADFGGGSMLVLLGITAALYERERSGRGQVIDAAMV
MSMEG_5734|M.smegmatis_MC2_155      IGYRDRPPVAPMNLVADFGGGSMLVLVGIVSALYERERSGKGQVIDAAMV
MAB_0845|M.abscessus_ATCC_1997      MGYKDRPPMPPMNLVADFGGGSMLLVQGILAALYEREKSGKGQVIDGAMV
Mflv_2126|M.gilvum_PYR-GCK          IGRHGERPVPPLNLAGDFGGGSMFLLVGVLAALWERERSGKGQVVDAAMV
Mvan_4578|M.vanbaalenii_PYR-1       IGRAGERPVPPLNLVGDFGGGSMFLLVGVLSALYERERSGKGQVVDAAMV
TH_4477|M.thermoresistible__bu      VGRKGERPVPPLNLAGDFGGGSMFLLVGILAALFERQTSGKGQVVDAAMI
MUL_0986|M.ulcerans_Agy99           IGRVGERPVPPLNLVGDFGGGSMFLLVGILAALWERHNSGKGQVIDAAMV
                                    .*  .. * .*:**..*******::: *:  **:**. ** ***:*.**:

Mb0878|M.bovis_AF2122/97            DGVSVLAQMMWTMKGIGSLRDQRESFLLDGGAPFYRCYETSDGKYMAVGA
Rv0855|M.tuberculosis_H37Rv         DGVSVLAQMMWTMKGIGSLRDQRESFLLDGGAPFYRCYETSDGKYMAVGA
MMAR_4681|M.marinum_M               DGVSVLAQMMWTMKGIGSLRDERESFLLDGGAPFYRCYETSDGKHMAVGA
MAV_0976|M.avium_104                DGVSLLAQMMWTMKSTGALRDRRESFLLDGGAPFYGCYETADGKYVAVGA
MSMEG_5734|M.smegmatis_MC2_155      DGVSMLAQMMWTMRATGSLRDERESFLLDGGAPFYRCYETADGGYMAVGS
MAB_0845|M.abscessus_ATCC_1997      DGVSQLAQMQWTMYNNGLLFDEREAGLLDGGSPFYGTYETSDGKYMAVGS
Mflv_2126|M.gilvum_PYR-GCK          DGSSVLSMMMWSFRGMGMWSDERGVNMLDTGAPYYDTYECSDGRHIAVGC
Mvan_4578|M.vanbaalenii_PYR-1       DGSSVLSMMMWAFRGMGMWSDERGTNMLDTGAPYYDTYETADGKYVAVGA
TH_4477|M.thermoresistible__bu      DGSAVLMQMMWAFRAMGMWSDERGVNMLDTGAPYYDTYETADGKYVAVGA
MUL_0986|M.ulcerans_Agy99           DGSSVLVQMMWAMRGIGIWSDVRGTNMLDGGAPYYDTYECADGGYVAVGA
                                    ** : *  * *::   *   * *   :** *:*:*  ** :** ::***.

Mb0878|M.bovis_AF2122/97            IEPQFFAALLSGLGLSAADVPTQLDVAGYPQMYDIFAERFASRTRDEWTR
Rv0855|M.tuberculosis_H37Rv         IEPQFFAALLSGLGLSAADVPTQLDVAGYPQMYDIFAERFASRTRDEWTR
MMAR_4681|M.marinum_M               IEPQFFAALLAGLGLSAAEVPSQLDIAAYPKMREMFSERFASRTRDEWAA
MAV_0976|M.avium_104                IEPQFFAALLDGLGLSPEEVPGQLDRDSYPRMREIFTQRFAGRTRDEWAR
MSMEG_5734|M.smegmatis_MC2_155      IEPQFFAQLVAGLGLAADEIPGQFEIGRYDEMRKIFTERFKTKTRAEWTE
MAB_0845|M.abscessus_ATCC_1997      IEPQFFAILVQGLGLDPESVPFQLDKARYPEMRKMFDDAFKTKTRDEWTE
Mflv_2126|M.gilvum_PYR-GCK          IEPQFYAEFLKGVGLEGADLPGQNDMGRWPELREAFSKAIAAHDRDHWAG
Mvan_4578|M.vanbaalenii_PYR-1       IEPQFYAEMLKGIGLDGADLPDQNDMSRWPELREAFTKAFAAHDRDHWAK
TH_4477|M.thermoresistible__bu      IEPQFYAEMLKGLGLEGEDLPDQNDMSRWDELRARFAEVFKSKDRDHWAQ
MUL_0986|M.ulcerans_Agy99           IEPQFYAAMLAGLGLDAVNLPPQNDVARWPELRAVLTEAFGRYDRDHWAK
                                    *****:* :: *:**   .:* * :   : .:   : . :    * .*: 

Mb0878|M.bovis_AF2122/97            VFAGTDACVTPVLAWSEAANNDHLKARSTVIT-AHGVQQAAPAPRFSRTP
Rv0855|M.tuberculosis_H37Rv         VFAGTDACVTPVLAWSEAANNDHLKARSTVIT-AHGVQQAAPAPRFSRTP
MMAR_4681|M.marinum_M               VFAGTDACVTPVLKWSEAAASDHLRARSTVIS-AHGVEQAAPAPRFSRTP
MAV_0976|M.avium_104                VFAGTDACVTPVLTWSEAAASEHLRARSTVIT-AHGVDQAAPAPRFSHTP
MSMEG_5734|M.smegmatis_MC2_155      IFAGTDACVTPVLTWGEAAENAHLRERSTLID-VDGVAQAAPAPRFSRTP
MAB_0845|M.abscessus_ATCC_1997      IFIGTDACVSPVLTWGEAKQNEHLRDRGTIVD-VDGVTQAAPAPRFSRTP
Mflv_2126|M.gilvum_PYR-GCK          VFAGTDACVTPVLSFAEVESEPHNTERDTFYS-ENGSLYPAPAPRFSRSV
Mvan_4578|M.vanbaalenii_PYR-1       VFAGTDACVTPVLSFAEVESEPHNTERDTFYS-ENGSLYPAPAPRFSRSA
TH_4477|M.thermoresistible__bu      VFAGTDACVTPVLSFAEVESEAHVVERNTFYR-EGDHLLPAPAPRFSRSV
MUL_0986|M.ulcerans_Agy99           VFADSDACVTPVLSFGEVHTEPHIAERNTFYEGDDGGPQPMPAPRFSRTV
                                    :* .:****:*** :.*.  . *   *.*.     .   . ******:: 

Mb0878|M.bovis_AF2122/97            AGPVRPP--PAAATPIDEINW-
Rv0855|M.tuberculosis_H37Rv         AGPVRPP--PAAATPIDEINW-
MMAR_4681|M.marinum_M               AGPVGPP--PATITPIGEINW-
MAV_0976|M.avium_104                ARPVGRP--PATSTPLDEINW-
MSMEG_5734|M.smegmatis_MC2_155      APTPGKP--PQGSTSIEDIGWD
MAB_0845|M.abscessus_ATCC_1997      SGPLGAP--PKDTTELSDIGW-
Mflv_2126|M.gilvum_PYR-GCK          PSAPKAPGVPGADTEAVLQEWV
Mvan_4578|M.vanbaalenii_PYR-1       PSAPKPPGVPGADTEAVLREWV
TH_4477|M.thermoresistible__bu      PSAPTPPRDPGADTDAVLQDWQ
MUL_0986|M.ulcerans_Agy99           PSRPRPPAAPLTDVEAVLSDWA
                                    .     *  *   .      *