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TGTLPLAGIKVLDLSTLLPGPLATLMLAEAGADVIKLERPGRGDEMRTYEPTFGEASANYAILNRGKRAY AVDFKDPAQRDRVLEIAADADIVMEQFRPGVAERLGLSYDAMRERNPRIVYCSISGYGPTGQHASRAGHD LNYLAESGLLGVVTDANGSPNLPVSVLADIAAGTYPAVMNVLLALRMAERTGEGAHLQVSMTHNLQVLAY GYIATHQAAGTWPQPSAELLTGGSPRYQIYPAADGRYIACAALEEKFWQRLVTLVGLDKRFHDDVGQEQA VTAALTDIFASQPSSYWRELLAGEDVCTVVVNTWEEAVEAGHVNINSADRVCVPGDPDLSIPTLTTSVDP TLRIPDNTRAYPSLAPLPDGHVVWA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4111 | - | - | 100% (376) | alpha-methylacyl-CoA racemase |
| M. smegmatis MC2 155 | MSMEG_5734 | - | 5e-50 | 32.33% (331) | alpha-methylacyl-CoA racemase |
| M. smegmatis MC2 155 | MSMEG_5184 | - | 3e-49 | 32.51% (323) | alpha-methylacyl-CoA racemase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0878 | far | 1e-50 | 35.35% (331) | fatty-acid-CoA racemase |
| M. gilvum PYR-GCK | Mflv_2126 | - | 2e-45 | 31.68% (322) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv0855 | far | 1e-50 | 35.35% (331) | fatty-acid-CoA racemase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0845 | - | 1e-48 | 33.85% (325) | fatty-acid-CoA racemase Far |
| M. marinum M | MMAR_4681 | far | 2e-49 | 33.23% (331) | fatty-acid-CoA racemase Far |
| M. avium 104 | MAV_0976 | - | 7e-49 | 33.13% (326) | alpha-methylacyl-CoA racemase |
| M. thermoresistible (build 8) | TH_4477 | - | 3e-45 | 30.96% (323) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_0986 | mcr | 2e-43 | 28.76% (379) | alpha-methylacyl-CoA racemase Mcr |
| M. vanbaalenii PYR-1 | Mvan_4578 | - | 2e-48 | 32.61% (322) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0878|M.bovis_AF2122/97 MTTG----GPLAGVKVIELGGIGPGPHAGMVLADLGADVVRVRRPG----
Rv0855|M.tuberculosis_H37Rv MTTG----GPLAGVKVIELGGIGPGPHAGMVLADLGADVVRVRRPG----
MMAR_4681|M.marinum_M MAGG----GPLAGVKVIELGGIGPGPHAGMVLADLGADVVRVRRPG----
MAV_0976|M.avium_104 MSSG----GPLAGVRVIELGGIGPGPHAGMVLADLGADVVRVRRPG----
MAB_0845|M.abscessus_ATCC_1997 MADTGVKTGPLAGVKVIELGGIGPGPHAAMMLSDLGADVIRVRRPG----
Mflv_2126|M.gilvum_PYR-GCK MAG------PLQGLRVVELAGIGPGPHAAMIFGDLGADVVRIERPGKG--
Mvan_4578|M.vanbaalenii_PYR-1 MAG------PLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPGKG--
TH_4477|M.thermoresistible__bu MAG------PLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPRNT--
MUL_0986|M.ulcerans_Agy99 MSG------PLNGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSS--
MSMEG_4111|M.smegmatis_MC2_155 MTGT----LPLAGIKVLDLSTLLPGPLATLMLAEAGADVIKLERPGRGDE
*: ** *::*::*. : *** * :::.: ****::: **
Mb0878|M.bovis_AF2122/97 ------GLTMPSEDRDLLHRGKRIVDLDVKTQP--QAMLELAAKADVLLD
Rv0855|M.tuberculosis_H37Rv ------GLTMPSEDRDLLHRGKRIVDLDVKTQP--QAMLELAAKADVLLD
MMAR_4681|M.marinum_M ------GLQMPAEDRDLLHRGKRIVDLDVKSQP--QALLELAAKADVLLD
MAV_0976|M.avium_104 ------VAAMPSEDRDLLHRGKRIVDLDVKARP--QALLDLAAKADVLLD
MAB_0845|M.abscessus_ATCC_1997 ------GLAIPAEETDLFHRGKRLVNLDVKKDP--EALLALVDKADVLLD
Mflv_2126|M.gilvum_PYR-GCK -----PGPATKPGG-DYLLRNRRSVAANLKSDEDREMVLRLIAKADVLIE
Mvan_4578|M.vanbaalenii_PYR-1 -----PGPATKPGG-DYLLRNRRSVAANLKSEEDRDMVLRLIAKADVLIE
TH_4477|M.thermoresistible__bu -----PGPGIPRGAKDHLLRNRRSVAADLKTEEGKELVRKLIAKADVLIE
MUL_0986|M.ulcerans_Agy99 -----AG-GRGGGVKDAMLRNRRIVTADLKSDQGRELVLKLVAKADVLIE
MSMEG_4111|M.smegmatis_MC2_155 MRTYEPTFGEASANYAILNRGKRAYAVDFKDPAQRDRVLEIAADADIVME
: *.:* :.* : : : .**::::
Mb0878|M.bovis_AF2122/97 CFRPGTCERLGIGPDDCASVNPRLIFARITGWGQDGPLASTAGHDINYLS
Rv0855|M.tuberculosis_H37Rv CFRPGTCERLGIGPDDCASVNPRLIFARITGWGQDGPLASTAGHDINYLS
MMAR_4681|M.marinum_M CFRPGTCERLGIGPDDCAAVNPRLIFARITGWGQDGPLAPTAGHDINYLS
MAV_0976|M.avium_104 CFRPGTCERLGIGPDDCAAVNPRLIFARITGWGQHGPLAQTAGHDINYLS
MAB_0845|M.abscessus_ATCC_1997 PFRPGVCERIGIGPEECAKRNPRLIFARMTGWGQHGPMADRAGHDINYLS
Mflv_2126|M.gilvum_PYR-GCK GFRPGVTERLGLGPEDCAKVNEKLVYARMTGWGQDGPRAQQAGHDINYIS
Mvan_4578|M.vanbaalenii_PYR-1 GFRPGVTERLGLGPHDCAKVNEKLIYARMTGWGQDGPRAQQAGHDINYIS
TH_4477|M.thermoresistible__bu GYRPGVTERLGLGPEDCAKINPRLIYGRMTGWGQDGPRAQQAGHDINYIS
MUL_0986|M.ulcerans_Agy99 GYRPGVTERLGLGPQDCAKVNDRLIYARMTGWGQAGPRSQQAGHDINYIS
MSMEG_4111|M.smegmatis_MC2_155 QFRPGVAERLGLSYDAMRERNPRIVYCSISGYGPTGQHASRAGHDLNYLA
:***. **:*:. . * :::: ::*:* * : ****:**::
Mb0878|M.bovis_AF2122/97 QTGALAAFGYADRPPMPPLNLVADFGGGSMLVLLGIVVALYERERSGVGQ
Rv0855|M.tuberculosis_H37Rv QTGALAAFGYADRPPMPPLNLVADFGGGSMLVLLGIVVALYERERSGVGQ
MMAR_4681|M.marinum_M QTGALSALGYRDRPPTPPLNLVADFGGGSMLVLLGIMAALYERERSGQGQ
MAV_0976|M.avium_104 QTGVLSALGHADRPPLPPLNLVADFGGGSMLVLLGITAALYERERSGRGQ
MAB_0845|M.abscessus_ATCC_1997 LTGALGSMGYKDRPPMPPMNLVADFGGGSMLLVQGILAALYEREKSGKGQ
Mflv_2126|M.gilvum_PYR-GCK LNGVLHAIGRHGERPVPPLNLAGDFGGGSMFLLVGVLAALWERERSGKGQ
Mvan_4578|M.vanbaalenii_PYR-1 LNGALHAIGRAGERPVPPLNLVGDFGGGSMFLLVGVLSALYERERSGKGQ
TH_4477|M.thermoresistible__bu LNGTLHAVGRKGERPVPPLNLAGDFGGGSMFLLVGILAALFERQTSGKGQ
MUL_0986|M.ulcerans_Agy99 LNGILHAIGRVGERPVPPLNLVGDFGGGSMFLLVGILAALWERHNSGKGQ
MSMEG_4111|M.smegmatis_MC2_155 ESGLLGVVTDANGSPNLPVSVLADIAAGTYPAVMNVLLALRMAERTGEGA
.* * . . * *:.: .*:..*: : .: ** . :* *
Mb0878|M.bovis_AF2122/97 VVDAAMVDGVSVLAQMMWTMKGIGSLRDQRESFLLDGGAPFYRCYETSDG
Rv0855|M.tuberculosis_H37Rv VVDAAMVDGVSVLAQMMWTMKGIGSLRDQRESFLLDGGAPFYRCYETSDG
MMAR_4681|M.marinum_M VIDAAMVDGVSVLAQMMWTMKGIGSLRDERESFLLDGGAPFYRCYETSDG
MAV_0976|M.avium_104 VIDAAMVDGVSLLAQMMWTMKSTGALRDRRESFLLDGGAPFYGCYETADG
MAB_0845|M.abscessus_ATCC_1997 VIDGAMVDGVSQLAQMQWTMYNNGLLFDEREAGLLDGGSPFYGTYETSDG
Mflv_2126|M.gilvum_PYR-GCK VVDAAMVDGSSVLSMMMWSFRGMGMWSDERGVNMLDTGAPYYDTYECSDG
Mvan_4578|M.vanbaalenii_PYR-1 VVDAAMVDGSSVLSMMMWAFRGMGMWSDERGTNMLDTGAPYYDTYETADG
TH_4477|M.thermoresistible__bu VVDAAMIDGSAVLMQMMWAFRAMGMWSDERGVNMLDTGAPYYDTYETADG
MUL_0986|M.ulcerans_Agy99 VIDAAMVDGSSVLVQMMWAMRGIGIWSDVRGTNMLDGGAPYYDTYECADG
MSMEG_4111|M.smegmatis_MC2_155 HLQVSMTHNLQVLAYGYIATHQAAGTWPQPSAELLTGGSPRYQIYPAADG
:: :* .. * : . :* *:* * * :**
Mb0878|M.bovis_AF2122/97 KYMAVGAIEPQFFAALLSGLGLSAADVPTQLDVAGYPQMYDIFAERFASR
Rv0855|M.tuberculosis_H37Rv KYMAVGAIEPQFFAALLSGLGLSAADVPTQLDVAGYPQMYDIFAERFASR
MMAR_4681|M.marinum_M KHMAVGAIEPQFFAALLAGLGLSAAEVPSQLDIAAYPKMREMFSERFASR
MAV_0976|M.avium_104 KYVAVGAIEPQFFAALLDGLGLSPEEVPGQLDRDSYPRMREIFTQRFAGR
MAB_0845|M.abscessus_ATCC_1997 KYMAVGSIEPQFFAILVQGLGLDPESVPFQLDKARYPEMRKMFDDAFKTK
Mflv_2126|M.gilvum_PYR-GCK RHIAVGCIEPQFYAEFLKGVGLEGADLPGQNDMGRWPELREAFSKAIAAH
Mvan_4578|M.vanbaalenii_PYR-1 KYVAVGAIEPQFYAEMLKGIGLDGADLPDQNDMSRWPELREAFTKAFAAH
TH_4477|M.thermoresistible__bu KYVAVGAIEPQFYAEMLKGLGLEGEDLPDQNDMSRWDELRARFAEVFKSK
MUL_0986|M.ulcerans_Agy99 GYVAVGAIEPQFYAAMLAGLGLDAVNLPPQNDVARWPELRAVLTEAFGRY
MSMEG_4111|M.smegmatis_MC2_155 RYIACAALEEKFWQRLVTLVGLDKR---FHDDVGQEQAVTAALTDIFASQ
::* ..:* :*: :: :**. : * : : . :
Mb0878|M.bovis_AF2122/97 TRDEWTRVFAGTDACVTPVLAWSEAANNDHLKARSTVIT-AHGVQQAAPA
Rv0855|M.tuberculosis_H37Rv TRDEWTRVFAGTDACVTPVLAWSEAANNDHLKARSTVIT-AHGVQQAAPA
MMAR_4681|M.marinum_M TRDEWAAVFAGTDACVTPVLKWSEAAASDHLRARSTVIS-AHGVEQAAPA
MAV_0976|M.avium_104 TRDEWARVFAGTDACVTPVLTWSEAAASEHLRARSTVIT-AHGVDQAAPA
MAB_0845|M.abscessus_ATCC_1997 TRDEWTEIFIGTDACVSPVLTWGEAKQNEHLRDRGTIVD-VDGVTQAAPA
Mflv_2126|M.gilvum_PYR-GCK DRDHWAGVFAGTDACVTPVLSFAEVESEPHNTERDTFYS-ENGSLYPAPA
Mvan_4578|M.vanbaalenii_PYR-1 DRDHWAKVFAGTDACVTPVLSFAEVESEPHNTERDTFYS-ENGSLYPAPA
TH_4477|M.thermoresistible__bu DRDHWAQVFAGTDACVTPVLSFAEVESEAHVVERNTFYR-EGDHLLPAPA
MUL_0986|M.ulcerans_Agy99 DRDHWAKVFADSDACVTPVLSFGEVHTEPHIAERNTFYEGDDGGPQPMPA
MSMEG_4111|M.smegmatis_MC2_155 PSSYWRELLAGEDVCTVVVNTWEEAVEAGHVNINSADRVCVPGDPD-LSI
. * :: . *.*. * : *. * ..: . .
Mb0878|M.bovis_AF2122/97 PRFSRTPAGPVRPP-------PAAATPIDEINW-
Rv0855|M.tuberculosis_H37Rv PRFSRTPAGPVRPP-------PAAATPIDEINW-
MMAR_4681|M.marinum_M PRFSRTPAGPVGPP-------PATITPIGEINW-
MAV_0976|M.avium_104 PRFSHTPARPVGRP-------PATSTPLDEINW-
MAB_0845|M.abscessus_ATCC_1997 PRFSRTPSGPLGAP-------PKDTTELSDIGW-
Mflv_2126|M.gilvum_PYR-GCK PRFSRSVPSAPKAPG-----VPGADTEAVLQEWV
Mvan_4578|M.vanbaalenii_PYR-1 PRFSRSAPSAPKPPG-----VPGADTEAVLREWV
TH_4477|M.thermoresistible__bu PRFSRSVPSAPTPPR-----DPGADTDAVLQDWQ
MUL_0986|M.ulcerans_Agy99 PRFSRTVPSRPRPPA-----APLTDVEAVLSDWA
MSMEG_4111|M.smegmatis_MC2_155 PTLTTSVDPTLRIPDNTRAYPSLAPLPDGHVVWA
* :: : * . *