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MRELRVVGLDVDGKRIICETADSAEMFTLRVDDRLRAALRGDKVASNQTEIDLEVQSVLRPKEIQAKIRA GASVEQLAAAAGVPVERVERFAHPVLLERARAAELATAAHPVLADGPSVLTLLETVTKALVARGLDPDAV AWDAWRNEDSRWTVQLAWKAGRSDNVAHFRFTPGSHGGLVTASDDAAHQLINPDFARPLRPVAAVPQLEF EAPQPAQPAAPPQPAQAVPTPEPAPAPEQEPEPAPAPAPKRSRKARATVPAWEDVLLGVRSSGTQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5685 | - | - | 100% (276) | DNA-binding protein |
| M. smegmatis MC2 155 | MSMEG_6099 | - | 2e-07 | 50.88% (57) | transmembrane protein rich in alanine |
| M. smegmatis MC2 155 | MSMEG_4265 | - | 3e-07 | 35.63% (87) | MmpS3 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0907c | - | 1e-97 | 64.10% (273) | hypothetical protein Mb0907c |
| M. gilvum PYR-GCK | Mflv_1717 | - | 1e-113 | 73.74% (278) | hypothetical protein Mflv_1717 |
| M. tuberculosis H37Rv | Rv0883c | - | 1e-97 | 64.10% (273) | hypothetical protein Rv0883c |
| M. leprae Br4923 | MLBr_02137 | - | 9e-91 | 61.90% (273) | hypothetical protein MLBr_02137 |
| M. abscessus ATCC 19977 | MAB_0883c | - | 5e-91 | 61.31% (274) | hypothetical protein MAB_0883c |
| M. marinum M | MMAR_4649 | - | 3e-97 | 63.14% (274) | hypothetical protein MMAR_4649 |
| M. avium 104 | MAV_1010 | - | 3e-90 | 62.64% (273) | hypothetical protein MAV_1010 |
| M. thermoresistible (build 8) | TH_1481 | ftsY | 2e-06 | 48.98% (49) | PROBABLE CELL DIVISION PROTEIN FTSY (SRP RECEPTOR) (SIGNAL |
| M. ulcerans Agy99 | MUL_0267 | - | 7e-97 | 63.00% (273) | hypothetical protein MUL_0267 |
| M. vanbaalenii PYR-1 | Mvan_5034 | - | 1e-113 | 74.64% (276) | hypothetical protein Mvan_5034 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1717|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5685|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4649|M.marinum_M --------------------------------------------------
MUL_0267|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02137|M.leprae_Br4923 --------------------------------------------------
MAV_1010|M.avium_104 --------------------------------------------------
Mb0907c|M.bovis_AF2122/97 --------------------------------------------------
Rv0883c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0883c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1481|M.thermoresistible__bu VSEGLWIAIAIIAVVLVAALIVGLVLYRRRRIRLTKRDEAKPVERGGGYT
Mflv_1717|M.gilvum_PYR-GCK ----------------------MRELKVVGLDVDGTRIICETGDSGE---
Mvan_5034|M.vanbaalenii_PYR-1 ----------------------MRELRVVGLDVDGRRIICETGDSGE---
MSMEG_5685|M.smegmatis_MC2_155 ----------------------MRELRVVGLDVDGKRIICETADSAE---
MMAR_4649|M.marinum_M ----------------------MRELRVVGLDADGKYILCEGVDSSE---
MUL_0267|M.ulcerans_Agy99 ----------------------MRELRVVGLDADGKYILCEGVDSTE---
MLBr_02137|M.leprae_Br4923 ----------------------MRELKVVGLDPDSKTILCEGDIPGE---
MAV_1010|M.avium_104 ----------------------MRELKVVGLDADSKYLICESDDPAE---
Mb0907c|M.bovis_AF2122/97 ----------------------MRELKVVGLDADGKNIICQGAIPSE---
Rv0883c|M.tuberculosis_H37Rv ----------------------MRELKVVGLDADGKNIICQGAIPSE---
MAB_0883c|M.abscessus_ATCC_199 ----------------------MRELKVIGLSADGKRVICQDANGTD---
TH_1481|M.thermoresistible__bu TSSGITFSQSATPTKAPPTKAAPERIDTTGLPGVGDDATIPRDAPKRPIA
..: . ** .
Mflv_1717|M.gilvum_PYR-GCK ----------------KFVLRADDRLKAAVRGDRAASNQTTIDVEVPNML
Mvan_5034|M.vanbaalenii_PYR-1 ----------------KFVLRSDDRLKAAVRGDRAGSNQTTIDVEVPTLL
MSMEG_5685|M.smegmatis_MC2_155 ----------------MFTLRVDDRLRAALRGDKVASNQTEIDLEVQSVL
MMAR_4649|M.marinum_M ----------------KYKLPADDRLRAALKRQSIPPEQPQLDIEVTNML
MUL_0267|M.ulcerans_Agy99 ----------------KYKLPADDRLRAALKRQPIPPEQPQLDIEVTNML
MLBr_02137|M.leprae_Br4923 ----------------RFKLPADDRLRAAVRGDTTLLDQPQLDIQVTNML
MAV_1010|M.avium_104 ----------------QFKLPADDHLRAVLRHEAEPPEQPQLEIEVTNML
Mb0907c|M.bovis_AF2122/97 ----------------QFKLPVDDRLRAALRDDSVQPEQAQLDIEVTNVL
Rv0883c|M.tuberculosis_H37Rv ----------------QFKLPVDDRLRAALRDDSVQPEQAQLDIEVTNVL
MAB_0883c|M.abscessus_ATCC_199 ----------------KFAIDADDRLRAAARGDLSRLGQIQIEMESS--L
TH_1481|M.thermoresistible__bu DVRLPEPPAAPPKPPPPAEVPPTEPPAPPVATPSPAETAPPVEPEAAPET
: : . :: :
Mflv_1717|M.gilvum_PYR-GCK RPREIQSKIRAGASVEQIASAAG------VDIARVERFAHPVLLERSRAA
Mvan_5034|M.vanbaalenii_PYR-1 RPREIQSKIRAGASVEQVAASAG------VDIARVERFAHPVLLERARAA
MSMEG_5685|M.smegmatis_MC2_155 RPKEIQAKIRAGASVEQLAAAAG------VPVERVERFAHPVLLERARAA
MMAR_4649|M.marinum_M SPKEIQARIRAGASVEQVATASG------SDIARIQRFAHPVLLERSRAA
MUL_0267|M.ulcerans_Agy99 SPKEIQARIRAGASVEQVATASG------SDIARIQRFAHPVLLERSRAA
MLBr_02137|M.leprae_Br4923 SPKEIQARIRAGASVEQVAMASG------SDIARIRRFAHPVLLERSRAA
MAV_1010|M.avium_104 SPKEIQAKIRAGASVEQVAAASG------SDVSRVRRFAHPVLLERYRAA
Mb0907c|M.bovis_AF2122/97 SPKEIQARIRAGASVEQVAAASG------SDIARIRRFAHPVLLERSRAA
Rv0883c|M.tuberculosis_H37Rv SPKEIQARIRAGASVEQVAAASG------SDIARIRRFAHPVLLERSRAA
MAB_0883c|M.abscessus_ATCC_199 RPREIQARIRAGATVQQVATAAG------VDVSRIERFAHPVLLERQRAA
TH_1481|M.thermoresistible__bu TPEPEPGAAPAAPQLDEIAPAEGRLDRLRGRLAKSQTAIGRSMLGLLGGG
*. . *.. ::::* : * : : . :* ..
Mflv_1717|M.gilvum_PYR-GCK ELATAAHPVLAD-------GPSVLT-LLETVSTALIARGLDPEATTWDAW
Mvan_5034|M.vanbaalenii_PYR-1 ELASAAHPVLAD-------GPSVLT-LLETVTSALIARGLDPDGANWDAW
MSMEG_5685|M.smegmatis_MC2_155 ELATAAHPVLAD-------GPSVLT-LLETVTKALVARGLDPDAVAWDAW
MMAR_4649|M.marinum_M ELATAAHPMLAD-------GPAVLT-LLETITAALVTRGLNPERLDWDAW
MUL_0267|M.ulcerans_Agy99 ELATAAHPMLAD-------GPAVLT-LLETITAALVTRGLNPERLDWDAW
MLBr_02137|M.leprae_Br4923 ELATAAHPVLAD-------GPAVLT-LLETVSAALVKRGLEPDKLSWDAW
MAV_1010|M.avium_104 ELATAAHPMLAD-------GPAVLT-LLETVTAAFVTRGLRHDKLSWDAW
Mb0907c|M.bovis_AF2122/97 ELATAAHPVLAD-------GPAVLT-MQETVAAALVARGLNPDSLTWDAW
Rv0883c|M.tuberculosis_H37Rv ELATAAHPVLAD-------GPAVLT-MQETVAAALVARGLNPDSLTWDAW
MAB_0883c|M.abscessus_ATCC_199 EMASAAHPVRND-------GPAVST-LADTVAGAMFARGGDPDAIEWDAW
TH_1481|M.thermoresistible__bu DLDEESWEEIEDTLLIADLGPVVTTSVVEKLREQMAASRVRTEADARAVL
:: : * ** * * : :.: : : .
Mflv_1717|M.gilvum_PYR-GCK RN---EDSRWTVQLAWKAGLSDNVAHFRYAPGAHG-GTVTAFDDAASELI
Mvan_5034|M.vanbaalenii_PYR-1 RN---EDSRWTVQLAWKAGLSDNVAHFRYAPGAHG-GTVTAFDDAAAELI
MSMEG_5685|M.smegmatis_MC2_155 RN---EDSRWTVQLAWKAGRSDNVAHFRFTPGSHG-GLVTASDDAAHQLI
MMAR_4649|M.marinum_M RN---EDGRWTVQLAWKAGRSDNLAHFRFAPGAHG-GTVTAIDDAASELI
MUL_0267|M.ulcerans_Agy99 RN---EDGRWTVQLAWKAGRSDNLAHFRFAPGAHG-GTVTAIDDAASELI
MLBr_02137|M.leprae_Br4923 RN---EDSRWTVQLMWHAGRSDNLAHFCFTPGAHG-GTVTASDDAANELI
MAV_1010|M.avium_104 RN---EDNRWTVQLAWKVGRSDNVAHFCFTPGAHG-GTVTAIDDAATALI
Mb0907c|M.bovis_AF2122/97 RN---EDSRWTVQLAWKAGRSDNLAHFRFTPGAHG-GTATAIDDTAHELI
Rv0883c|M.tuberculosis_H37Rv RN---EDSRWTVQLAWKAGRSDNLAHFRFTPGAHG-GTATAIDDTAHELI
MAB_0883c|M.abscessus_ATCC_199 KV---EDGRWTVQLQWRTGRSDNKAHFRYTPGAHG-GTVTALDDSARELI
TH_1481|M.thermoresistible__bu REVLISELRPDLDRSVKALPHDDKPSVLLVVGVNGTGKTTTVGKLARVLV
: .: * :: :. *: . . . * :* * .*: .. * *:
Mflv_1717|M.gilvum_PYR-GCK DPTFARPLRP-----LAPVAQLA---------LGEPEPAPAPTP------
Mvan_5034|M.vanbaalenii_PYR-1 DPNFARPLRP-----VAAVAQLA---------LGEPEDPHAPVQ------
MSMEG_5685|M.smegmatis_MC2_155 NPDFARPLRP-----VAAVPQLE---------FEAPQPAQPAAPPQPAQA
MMAR_4649|M.marinum_M DPEYKAPLRP-----LAPVSHLA---------FDEPAKPAKQAKPAKPAK
MUL_0267|M.ulcerans_Agy99 DPEYKAPLRP-----LAPVSHLA---------FDEPAKPAKQAKPAKPPK
MLBr_02137|M.leprae_Br4923 DPDFNRPLRP-----LARVAHLD---------FVEPATPATVT-------
MAV_1010|M.avium_104 DPNFELPLRP-----LARVAHVD---------FDEPAKPPTAEAPA----
Mb0907c|M.bovis_AF2122/97 NPTFNRPLRP-----LAPVAHLD---------FDEPE-PAQPT-------
Rv0883c|M.tuberculosis_H37Rv NPTFNRPLRP-----LAPVAHLD---------FDEPE-PAQPT-------
MAB_0883c|M.abscessus_ATCC_199 DPTFTRSLRP-----VAAVSPLLPEPEPE--LFTESPAPLPEPEPAVAEE
TH_1481|M.thermoresistible__bu ADGRRVVLGAADTFRAAAADQLETWASRVGAEVVRGREGADPASVAFDAV
* . * . : .
Mflv_1717|M.gilvum_PYR-GCK APAPAPAPAPESIPEPQAEAPEDTPAAKTSRPRKSRPAVPAWEDVLLGVR
Mvan_5034|M.vanbaalenii_PYR-1 AATPAPEPAPVETPEP-------APTVKTPRPRKSRPAVPAWEDVLLGVR
MSMEG_5685|M.smegmatis_MC2_155 VPTPEPAPAPEQEPEP-------APAPAPKRSRKARATVPAWEDVLLGVR
MMAR_4649|M.marinum_M QTPPAPAEQPAS-------------------SRRGKPAIPAWEDVLLGVR
MUL_0267|M.ulcerans_Agy99 QTPPAPAEQPAS-------------------SRRGKPAIPAWEDVLLGVR
MLBr_02137|M.leprae_Br4923 -----PDNQLVS-------------------SRRGKPTIPAWEDVLLGVR
MAV_1010|M.avium_104 AEPAEPEEKPVH-------------------TRRGKPVIPAWEDVLLGVR
Mb0907c|M.bovis_AF2122/97 --LTVPSAQPVS-------------------NRRGKPAIPAWEDVLLGVR
Rv0883c|M.tuberculosis_H37Rv --LTVPSAQPVS-------------------NRRGKPAIPAWEDVLLGVR
MAB_0883c|M.abscessus_ATCC_199 HTETETTQAPAP-----------------RRSRRSKPAVPTWEDVLLGVR
TH_1481|M.thermoresistible__bu DTGIKNGADVVLIDTAGRLHTKTGLMDELGKVKRVVKKRAAVDEVLLVLD
:: .: ::*** :
Mflv_1717|M.gilvum_PYR-GCK SSGGQR--------------------------------------------
Mvan_5034|M.vanbaalenii_PYR-1 SSGGQR--------------------------------------------
MSMEG_5685|M.smegmatis_MC2_155 SSGTQR--------------------------------------------
MMAR_4649|M.marinum_M SSG-QR--------------------------------------------
MUL_0267|M.ulcerans_Agy99 SSG-QR--------------------------------------------
MLBr_02137|M.leprae_Br4923 SAG-QR--------------------------------------------
MAV_1010|M.avium_104 SGG-QR--------------------------------------------
Mb0907c|M.bovis_AF2122/97 SGG-RR--------------------------------------------
Rv0883c|M.tuberculosis_H37Rv SGG-RR--------------------------------------------
MAB_0883c|M.abscessus_ATCC_199 SSG-QN--------------------------------------------
TH_1481|M.thermoresistible__bu ATIGQNSLPQAKVFAEVVDITGVVLTKLDGTAKGGIVFRVQQELGVPVKL
: :.
Mflv_1717|M.gilvum_PYR-GCK ------------------------
Mvan_5034|M.vanbaalenii_PYR-1 ------------------------
MSMEG_5685|M.smegmatis_MC2_155 ------------------------
MMAR_4649|M.marinum_M ------------------------
MUL_0267|M.ulcerans_Agy99 ------------------------
MLBr_02137|M.leprae_Br4923 ------------------------
MAV_1010|M.avium_104 ------------------------
Mb0907c|M.bovis_AF2122/97 ------------------------
Rv0883c|M.tuberculosis_H37Rv ------------------------
MAB_0883c|M.abscessus_ATCC_199 ------------------------
TH_1481|M.thermoresistible__bu VGLGEGPDDLAPFEPAAFVDALLG