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M. smegmatis MC2 155 MSMEG_5371 (ehuA)

annotation: ectoine/hydroxyectoine ABC transporter, ATP-binding protein
coordinates: 5448466 - 5449230
length: 254

MVRFENVVKRFGDKTVLDGMNFSVAPGERVTLIGPSGSGKTTILRLLMTLERVTDGVIWVDGEPFTHERR
GGRLVPASEKYLRRARRRIGMVFQQFNLFPNMTVIENLMEAPVSVLGLSKEQARARGTELLDKVGMTDFV
DAHPTTLSGGQQQRVAIARALAMEPDILLLDEVTSALDPELVVDVLGVLRDIADTTDITMLIVTHEMHFA
RDVSDRVLMFDKGVIIEDGPPSKIFNEPEHERTRTFLRAVLEER
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5371ehuA-100% (254)ectoine/hydroxyectoine ABC transporter, ATP-binding protein
M. smegmatis MC2 155MSMEG_3550ehuA3e-8259.13% (252) ectoine/hydroxyectoine ABC transporter, ATP-binding protein
M. smegmatis MC2 155MSMEG_3237-5e-6850.60% (251) ATP-binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2419ccysA19e-3936.73% (245) sulfate-transport ATP-binding protein ABC transporter CysA1
M. gilvum PYR-GCKMflv_3581-7e-6850.60% (251) ABC transporter related
M. tuberculosis H37RvRv2397ccysA19e-3936.73% (245) sulfate-transport ATP-binding protein ABC transporter CysA1
M. leprae Br4923MLBr_01122-3e-3334.29% (245) putative ABC transport protein, ATP-binding component
M. abscessus ATCC 19977MAB_4237c-2e-6146.80% (250) amino acid ABC transporter ATP-binding protein
M. marinum MMMAR_0060-9e-5243.90% (246) glutamine ABC transporter, ATP-binding protein
M. avium 104MAV_0058-3e-5144.53% (247) ABC transporter, ATP-binding protein
M. thermoresistible (build 8)TH_1784-5e-5846.61% (251) ABC transporter, ATP-binding protein GluA
M. ulcerans Agy99MUL_3658cysA16e-3836.78% (242) sulfate-transport ATP-binding protein ABC transporter CysA1
M. vanbaalenii PYR-1Mvan_2834-8e-6650.20% (251) ABC transporter-related protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2419c|M.bovis_AF2122/97           ----------MT------YAIVVADATKRYGDFVALDHVDFVVPTGSLTA
Rv2397c|M.tuberculosis_H37Rv        ----------MT------YAIVVADATKRYGDFVALDHVDFVVPTGSLTA
MUL_3658|M.ulcerans_Agy99           ----------MTGPGTGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTA
MMAR_0060|M.marinum_M               --------MTRQDAGRQPVCLAARSIHQTLGGSVVLRGVDLEVPAGTTAA
MAV_0058|M.avium_104                --------MS-NPASRASVSLACKDIHQTLNGNAVLRGVDLDTPAGSTVA
TH_1784|M.thermoresistible__bu      MDSAGADVAVADPAAEAVPMISMRGVNKYFGSLHVLRDINLDVARGQVVV
Mflv_3581|M.gilvum_PYR-GCK          ---------MTTSENSAHPMVKAELVCKDFGALKVLKGITLEVQKGQVLV
Mvan_2834|M.vanbaalenii_PYR-1       ---------MTADAVSAKPMVKAELVCKDFGALKVLKGITLEVQKGQVLV
MAB_4237c|M.abscessus_ATCC_199      ---------MSTIEVRG--------VRKSYGQVTALRDVNLTVHQGEVTV
MSMEG_5371|M.smegmatis_MC2_155      -------------------MVRFENVVKRFGDKTVLDGMNFSVAPGERVT
MLBr_01122|M.leprae_Br4923          ------------MSPLLEVTDLAVTFETNGEPVTAVRGISYRINAGEVVA
                                                                      .:  :      *   .

Mb2419c|M.bovis_AF2122/97           LLGPSGSGKSTLLRTIAGLD---QPDTGTITINGRDVTRVP---------
Rv2397c|M.tuberculosis_H37Rv        LLGPSGSGKSTLLRTIAGLD---QPDTGTITINGRDVTRVP---------
MUL_3658|M.ulcerans_Agy99           LLGPSGSGKSTLLRTIAGLD---QPDSGNITINGRDVTRVP---------
MMAR_0060|M.marinum_M               VIGPSGSGKSTLLRTLNRLH---EPDSGDILLDGRSVLRD----------
MAV_0058|M.avium_104                VIGPSGSGKSTLLRTLNRLY---EPDRGDILLDGRSVLHD----------
TH_1784|M.thermoresistible__bu      VLGPSGSGKSTLCRTLNRLE---PIDSGAISIDGVALPAEGR--------
Mflv_3581|M.gilvum_PYR-GCK          LVGPSGSGKSTLLRCINHLE---TVSAGRLYVDGTLVGYHERGGKLYEMK
Mvan_2834|M.vanbaalenii_PYR-1       LVGPSGSGKSTFLRCINHLE---TVSAGRLYVDGALVGYNERGGKLHEMK
MAB_4237c|M.abscessus_ATCC_199      IIGPSGSGKSTLLRALNHLE---KVDAGTIRIDGELIGYRQRGSVLYELP
MSMEG_5371|M.smegmatis_MC2_155      LIGPSGSGKTTILRLLMTLE---RVTDGVIWVDGEPFTHERRGGRLVPAS
MLBr_01122|M.leprae_Br4923          MVGESGSGKSAAAMAVVGLLPEYAQVRGSVRLHNTELVGLADKT------
                                    ::* *****::    :  *        * : :..  .             

Mb2419c|M.bovis_AF2122/97           -----PQRRGIGFVFQH-YAAFKHLTVRDNVAFG-LKIRK--RPKAEIKA
Rv2397c|M.tuberculosis_H37Rv        -----PQRRGIGFVFQH-YAAFKHLTVRDNVAFG-LKIRK--RPKAEIKA
MUL_3658|M.ulcerans_Agy99           -----PQRRGIGFVFQH-YAAFKHLTVRDNVAYG-LKIRK--RPKAEIRD
MMAR_0060|M.marinum_M               --NPNDLRQRIGMVFQH-FNLFPHRNVVDNVTLAPRKLRG--LSNEEARM
MAV_0058|M.avium_104                --DPDQLRQRIGMVFQH-FNLFPHRTVLDNVALAPRKLRR--LPAEAARE
TH_1784|M.thermoresistible__bu      --ELARLRADVGMVFQQ-FNLFAHKTIVDNVALGPMKVRK--TPREQARA
Mflv_3581|M.gilvum_PYR-GCK          PRDVARQRRDVGMVFQH-FNLFPHRTALGNVVEAPIQVKG--VKKDEAVT
Mvan_2834|M.vanbaalenii_PYR-1       PRDVAKQRRDVGMVFQH-FNLFPHRTALGNVVEAPIQVKG--VRKAQAIE
MAB_4237c|M.abscessus_ATCC_199      ERAILRQRSQVGFVFQN-FNLFPHLTVLENVIEAPLAARR--APRAELEA
MSMEG_5371|M.smegmatis_MC2_155      EKYLRRARRRIGMVFQQ-FNLFPNMTVIENLMEAPVSVLG--LSKEQARA
MLBr_01122|M.leprae_Br4923          --MSRFRGKAIGTVFQDPMSALTPVYTVGDQITEAIKVHQPRVGKKAAHR
                                              :* ***.    :       :                    

Mb2419c|M.bovis_AF2122/97           KVDNLLQVVGLSG---FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDE
Rv2397c|M.tuberculosis_H37Rv        KVDNLLQVVGLSG---FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDE
MUL_3658|M.ulcerans_Agy99           KVDNLLEVVGLSG---FHGRYPDQLSGGQRQRMALARALAVDPEVLLLDE
MMAR_0060|M.marinum_M               LALDQLDRVGLKH---KANARPDMLSGGQQQRVAIARALAMAPQVMFFDE
MAV_0058|M.avium_104                LALTQLDRVGLKH---KAGARPATLSGGQQQRVAIARALAMSPQVMFFDE
TH_1784|M.thermoresistible__bu      EAMALLERVGVAD---QADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDE
Mflv_3581|M.gilvum_PYR-GCK          RGRELLAQVGLAD---KADAYPAQLSGGQQQRVAIARALAMDPKLMLFDE
Mvan_2834|M.vanbaalenii_PYR-1       KGKELLAQVGLAD---KAGAYPAQLSGGQQQRVAIARALAMDPKLMLFDE
MAB_4237c|M.abscessus_ATCC_199      EATRLLERVGVAD---KAAQYPRRLSGGQQQRVAIARALALRPKVILFDE
MSMEG_5371|M.smegmatis_MC2_155      RGTELLDKVGMTD---FVDAHPTTLSGGQQQRVAIARALAMEPDILLLDE
MLBr_01122|M.leprae_Br4923          RAVELLELVGITQPDRRARAFPHELSGGERQRVVIATAIANDPDLLICDE
                                         *  **:          *  ****::**:.:* ::*  *.::: **

Mb2419c|M.bovis_AF2122/97           PFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHK
Rv2397c|M.tuberculosis_H37Rv        PFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHK
MUL_3658|M.ulcerans_Agy99           PFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNS
MMAR_0060|M.marinum_M               ATSALDPEMVKGILALIADLGADG-MTMVVVTHEMGFARSTSDAVVFMDH
MAV_0058|M.avium_104                ATSALDPEMVKGILQLIADLGAEG-MTMVVVTHEMGFARSASDAVIFMDH
TH_1784|M.thermoresistible__bu      PTSALDPEMINEVLAVMSALAADG-MTMLVVTHEMGFARRASDRVVFMSD
Mflv_3581|M.gilvum_PYR-GCK          PTSALDPELVGEVLAVMKKLAAQG-MTMVVVTHEMGFAREVADELVFMDE
Mvan_2834|M.vanbaalenii_PYR-1       PTSALDPELVGEVLGVMKKLAAQG-MTMVVVTHEMGFAREVADELVFMDA
MAB_4237c|M.abscessus_ATCC_199      PTSALDPELVTEVLDVIAQLARDG-ATLVIVTHEIGLAREIADTVVFMDR
MSMEG_5371|M.smegmatis_MC2_155      VTSALDPELVVDVLGVLRDIADTTDITMLIVTHEMHFARDVSDRVLMFDK
MLBr_01122|M.leprae_Br4923          PTTALDVTVQAQILEVLKTARDVTGAGVLIITHDLGVVTEFADQALVMYA
                                       ***  :   :   :           :::**:   .   :*   .:  

Mb2419c|M.bovis_AF2122/97           GRIEQVGSPTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMA
Rv2397c|M.tuberculosis_H37Rv        GRIEQVGSPTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMA
MUL_3658|M.ulcerans_Agy99           GRIEQVGSPTEVYDAPTNAFVMSFLGAVSALNGALVRPHDIRVGRTPEMA
MMAR_0060|M.marinum_M               GTVVEAGPPEQLFEAARTERLQRFLAQVL---------------------
MAV_0058|M.avium_104                GKVVESGPPEQIFEAAETERLQRFLSQVL---------------------
TH_1784|M.thermoresistible__bu      GAIVEDAEPARFFEDPQTDRARDFLGKILHH-------------------
Mflv_3581|M.gilvum_PYR-GCK          GVVVERGNPREVMSNPQHERTKAFLSKVM---------------------
Mvan_2834|M.vanbaalenii_PYR-1       GVVVERGAPREVMANPQHERTKAFLSKVM---------------------
MAB_4237c|M.abscessus_ATCC_199      GAIVEQGPPKEVLDSPSHPRTASFLSKVLS--------------------
MSMEG_5371|M.smegmatis_MC2_155      GVIIEDGPPSKIFNEPEHERTRTFLRAVLEER------------------
MLBr_01122|M.leprae_Br4923          GRVVESAQVSTLYRERQMPYTVGLLGSVPRLDATQGTRLVPIPGAPPSLA
                                    * : : .    .           :*  :                      

Mb2419c|M.bovis_AF2122/97           --------------------------VAAADGTAGSTGVLRAVVDRVVVL
Rv2397c|M.tuberculosis_H37Rv        --------------------------VAAADGTAGSTGVLRAVVDRVVVL
MUL_3658|M.ulcerans_Agy99           --------------------------VAAADGTGESTGVTRAVVDRIVVL
MMAR_0060|M.marinum_M               --------------------------------------------------
MAV_0058|M.avium_104                --------------------------------------------------
TH_1784|M.thermoresistible__bu      --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5371|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01122|M.leprae_Br4923          GLQQECPFAPRCPLVVDECRLREPELVEVRAGHRTACIRTDQVSGRSAAD
                                                                                      

Mb2419c|M.bovis_AF2122/97           GFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGG
Rv2397c|M.tuberculosis_H37Rv        GFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGG
MUL_3658|M.ulcerans_Agy99           GFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPPIAGA
MMAR_0060|M.marinum_M               --------------------------------------------------
MAV_0058|M.avium_104                --------------------------------------------------
TH_1784|M.thermoresistible__bu      --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5371|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01122|M.leprae_Br4923          IYGINTDTRTSATSDSSVVVRVRDLVKTYRLTKGVGLRRAIGEIRAVNGV
                                                                                      

Mb2419c|M.bovis_AF2122/97           VSGVDDAGVERVKVTST---------------------------------
Rv2397c|M.tuberculosis_H37Rv        VSGVDDAGVERVKVTST---------------------------------
MUL_3658|M.ulcerans_Agy99           APAVPDDGAGSTPRAAQIGVGGQ---------------------------
MMAR_0060|M.marinum_M               --------------------------------------------------
MAV_0058|M.avium_104                --------------------------------------------------
TH_1784|M.thermoresistible__bu      --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5371|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01122|M.leprae_Br4923          SFELQQGRTLGIVGESGSGKSTTLHEILRLAVPQSGSIEVLGIDVATLNR
                                                                                      

Mb2419c|M.bovis_AF2122/97           --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3658|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0060|M.marinum_M               --------------------------------------------------
MAV_0058|M.avium_104                --------------------------------------------------
TH_1784|M.thermoresistible__bu      --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5371|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01122|M.leprae_Br4923          ASRRSMRRNIQVVFQDPVASLDPRLPVFELIAEPLHANGFSKNYTQMRVA
                                                                                      

Mb2419c|M.bovis_AF2122/97           --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3658|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0060|M.marinum_M               --------------------------------------------------
MAV_0058|M.avium_104                --------------------------------------------------
TH_1784|M.thermoresistible__bu      --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5371|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01122|M.leprae_Br4923          ELLDIVGLRRDDATRYPTEFSGGQKQRIGIARALALQPKILAFDEPVSAL
                                                                                      

Mb2419c|M.bovis_AF2122/97           --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3658|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0060|M.marinum_M               --------------------------------------------------
MAV_0058|M.avium_104                --------------------------------------------------
TH_1784|M.thermoresistible__bu      --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5371|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01122|M.leprae_Br4923          DVSIQAGIINLLLDLQDRLGLSYLFVSHDLSVIKHLAHQVAVMLAGTIVE
                                                                                      

Mb2419c|M.bovis_AF2122/97           -----------------------------
Rv2397c|M.tuberculosis_H37Rv        -----------------------------
MUL_3658|M.ulcerans_Agy99           -----------------------------
MMAR_0060|M.marinum_M               -----------------------------
MAV_0058|M.avium_104                -----------------------------
TH_1784|M.thermoresistible__bu      -----------------------------
Mflv_3581|M.gilvum_PYR-GCK          -----------------------------
Mvan_2834|M.vanbaalenii_PYR-1       -----------------------------
MAB_4237c|M.abscessus_ATCC_199      -----------------------------
MSMEG_5371|M.smegmatis_MC2_155      -----------------------------
MLBr_01122|M.leprae_Br4923          QGDSHDVFRNPQHDYTRRLLGAIPRPEVG