For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TQLVPESAAAEPEGTVKIRIENLKKAFGDLVVLDGITTTVKKGEVVCVIGPSGSGKSTFLRCLNKLEDIT DGKVVVDEFDLTDRKVDLDKVRQRIGMVFQHFNLFPHMTVIDNITLAPLLTKKMDKPAAEKRAMELLGQV GLAEKAHVKPATLSGGQKQRVAIARALAMNPSIMLFDEATSALDPEMVGDVLEVLRDLAEGGMTMVVVTH EMGFAREVASRVMFMADGNIVEDDTPAEIFDNPKHPRLQDFLSKVL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5316 | - | - | 100% (257) | glutamine ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3237 | - | 8e-74 | 56.15% (260) | ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_0178 | - | 8e-72 | 54.80% (250) | ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0074 | - | 7e-36 | 41.12% (197) | glutamine-transport ATP-binding protein ABC transporter GlnQ |
| M. gilvum PYR-GCK | Mflv_3165 | - | 1e-125 | 86.77% (257) | ABC transporter related |
| M. tuberculosis H37Rv | Rv0073 | - | 8e-36 | 41.12% (197) | glutamine-transport ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_00669 | ftsE | 1e-32 | 36.65% (221) | putative cell division ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_3050 | - | 2e-72 | 56.49% (239) | putative glutamate ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 7e-62 | 52.07% (242) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 2e-64 | 52.48% (242) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_1784 | - | 9e-69 | 52.99% (251) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 6e-36 | 37.24% (239) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_4704 | - | 1e-130 | 90.66% (257) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5316|M.smegmatis_MC2_155 ---MTQLVPESAAAEPEGTVKIRIENLKKAFG--DLVVLDGITTTVKKGE
Mvan_4704|M.vanbaalenii_PYR-1 ---MNQLVTEAAAAEPVGTVKIRIEGLKKSFG--DHVVLDGISTTISKGE
Mflv_3165|M.gilvum_PYR-GCK ---MSELITEAAASEPAGTVKIRIEGLKKSFG--DLVVLDGIDTTVSHGE
MAB_3050|M.abscessus_ATCC_1997 MPVSTDTSTSGESSSAPSVPMIALEHVNKHFG--DLHVLKDITLEIPRGQ
TH_1784|M.thermoresistible__bu -MDSAGADVAVADPAAEAVPMISMRGVNKYFG--SLHVLRDINLDVARGQ
MMAR_0060|M.marinum_M ---------MTRQDAGRQPVCLAARSIHQTLG--GSVVLRGVDLEVPAGT
MAV_0058|M.avium_104 ---------MS-NPASRASVSLACKDIHQTLN--GNAVLRGVDLDTPAGS
MUL_3658|M.ulcerans_Agy99 -----------MTGPGTGGHAIVVRDAFKQYG--DFVALDHVDFVVPAGS
MLBr_00669|M.leprae_Br4923 --------------------MITLDHVSKKYKSLARPALDNVNVKIDKGE
Mb0074|M.bovis_AF2122/97 ----------------MGDLSIQNLVVEYYSGGYALRPINGLNLDVAAGS
Rv0073|M.tuberculosis_H37Rv ----------------MGDLSIQNLVVEYYSGGYALRPINGLNLDVAAGS
: : : *
MSMEG_5316|M.smegmatis_MC2_155 VVCVIGPSGSGKSTFLRCLNKLEDITDGKVVVDEFDLTDRK-VDLDKVRQ
Mvan_4704|M.vanbaalenii_PYR-1 VVCVIGPSGSGKSTFLRCLNKLEDISGGKVVVDEFDLTDPK-IDLDKVRQ
Mflv_3165|M.gilvum_PYR-GCK VVCVIGPSGSGKSTFLRCLNKLEDITGGRVVVDEFDLTDPK-IDLDKVRQ
MAB_3050|M.abscessus_ATCC_1997 VVVILGPSGSGKSTLCRTINRLEPIDGGTIRIDGAILPEEG-RALASLRA
TH_1784|M.thermoresistible__bu VVVVLGPSGSGKSTLCRTLNRLEPIDSGAISIDGVALPAEG-RELARLRA
MMAR_0060|M.marinum_M TAAVIGPSGSGKSTLLRTLNRLHEPDSGDILLDGRSVLRD---NPNDLRQ
MAV_0058|M.avium_104 TVAVIGPSGSGKSTLLRTLNRLYEPDRGDILLDGRSVLHD---DPDQLRQ
MUL_3658|M.ulcerans_Agy99 LTALLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVP-----PQRR
MLBr_00669|M.leprae_Br4923 FVFLIGPSGSGKSTFMRLLLGAETPTSGDVRVSKFHVNKLPGRHIPRLRQ
Mb0074|M.bovis_AF2122/97 LVMLLGPSGCGKTTLLSCLGGILRPKSGAIKFDEVDITTLQGAELANYRR
Rv0073|M.tuberculosis_H37Rv LVMLLGPSGCGKTTLLSCLGGILRPKSGAIKFDEVDITTLQGAELANYRR
. ::****.**:*: : * : .. : *
MSMEG_5316|M.smegmatis_MC2_155 R-IGMVFQHFNLFPHMTVIDNITLAPLLTKKMDKPAAEKRAMELLGQVGL
Mvan_4704|M.vanbaalenii_PYR-1 R-IGMVFQHFNLFPHMTVIENITLAPLLTKKMDKAAAEKKAMELLGQVGL
Mflv_3165|M.gilvum_PYR-GCK H-IGMVFQHFNLFPHMTVLENVTLAPLLTKKMDKAAAEKKALQLLDQVGL
MAB_3050|M.abscessus_ATCC_1997 E-VGMVFQSFNLFSHKTILDNVTLAPIKVRKHNKETARKRAIELLERVGI
TH_1784|M.thermoresistible__bu D-VGMVFQQFNLFAHKTIVDNVALGPMKVRKTPREQARAEAMALLERVGV
MMAR_0060|M.marinum_M R-IGMVFQHFNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQLDRVGL
MAV_0058|M.avium_104 R-IGMVFQHFNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQLDRVGL
MUL_3658|M.ulcerans_Agy99 G-IGFVFQHYAAFKHLTVRDNVAYG-LKIRKRPKAEIRDKVDNLLEVVGL
MLBr_00669|M.leprae_Br4923 V-IGCVFQDFRLLQQKTVYENVAFALEVIGRRS-DAINQVVPDVLETVGL
Mb0074|M.bovis_AF2122/97 NKVGIVFQAFNLVPSLTAVENVMVP-LRSAGMSRRASRRRAEELLARVNL
Rv0073|M.tuberculosis_H37Rv NKVGIVFQAFNLVPSLTAVENVMVP-LRSAGMSRRASRRRAEELLARVNL
:* *** : . . :*: . . * *.:
MSMEG_5316|M.smegmatis_MC2_155 AEKAHVKPATLSGGQKQRVAIARALAMNPSIMLFDEATSALDPEMVGDVL
Mvan_4704|M.vanbaalenii_PYR-1 AEKAHVKPATLSGGQKQRVAIARALAMNPSIMLFDEATSALDPEMVGDVL
Mflv_3165|M.gilvum_PYR-GCK AEKAGVKPATLSGGQKQRVAIARALAMNPSIMLFDEATSALDPEMVGDVL
MAB_3050|M.abscessus_ATCC_1997 ASQKDKYPAQLSGGQQQRVAIARSLAMGPKVMLFDEPTSALDPEMVNEVL
TH_1784|M.thermoresistible__bu ADQADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMINEVL
MMAR_0060|M.marinum_M KHKANARPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPEMVKGIL
MAV_0058|M.avium_104 KHKAGARPATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPEMVKGIL
MUL_3658|M.ulcerans_Agy99 SGFHGRYPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLR
MLBr_00669|M.leprae_Br4923 SGKANRLPDELSGGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDIM
Mb0074|M.bovis_AF2122/97 AERMNHRPGDLSGGQQQRVAVARAIALDPPLILADEPTAHLDFIQVEEVL
Rv0073|M.tuberculosis_H37Rv AERMNHRPGDLSGGQQQRVAVARAIALDPPLILADEPTAHLDFIQVEEVL
* ****::**:*:**::. * ::: **. . ** :
MSMEG_5316|M.smegmatis_MC2_155 EVLRDLAEGG-MTMVVVTHEMGFAREVASRVMFMADGNIVEDDTPAEIFD
Mvan_4704|M.vanbaalenii_PYR-1 QVLRDLAEGG-MTMVVVTHEMGFAREVASRVVFMADGDIVEDAPPAELFD
Mflv_3165|M.gilvum_PYR-GCK EVLRTLARGG-MTMVVVTHEMGFAREVASRVIFMADGHIVEEGPPAEIFD
MAB_3050|M.abscessus_ATCC_1997 DVMVSLAKEG-MTMLVVTHEMGFARKAADRIIFMADGAIVEDSDPESFFT
TH_1784|M.thermoresistible__bu AVMSALAADG-MTMLVVTHEMGFARRASDRVVFMSDGAIVEDAEPARFFE
MMAR_0060|M.marinum_M ALIADLGADG-MTMVVVTHEMGFARSTSDAVVFMDHGTVVEAGPPEQLFE
MAV_0058|M.avium_104 QLIADLGAEG-MTMVVVTHEMGFARSASDAVIFMDHGKVVESGPPEQIFE
MUL_3658|M.ulcerans_Agy99 AWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYD
MLBr_00669|M.leprae_Br4923 DLLERINRTG-TTVLMATHDHHIVDSMRQRVVELSLGRLVRDEWCG-IYG
Mb0074|M.bovis_AF2122/97 RLIRELADGE--RVVVVATHDSRMLPMADRVVELTPDFAETNRPPETVHL
Rv0073|M.tuberculosis_H37Rv RLIRELADGE--RVVVVATHDSRMLPMADRVVELTPDFAETNRPPETVHL
: : ::.: . . : : . ..
MSMEG_5316|M.smegmatis_MC2_155 NPKHPRLQDFLSKVL-----------------------------------
Mvan_4704|M.vanbaalenii_PYR-1 NPKHPRLQDFLAKVL-----------------------------------
Mflv_3165|M.gilvum_PYR-GCK NPKHPRLQEFLSKVL-----------------------------------
MAB_3050|M.abscessus_ATCC_1997 NPKSERAKDFLGKILGH---------------------------------
TH_1784|M.thermoresistible__bu DPQTDRARDFLGKILHH---------------------------------
MMAR_0060|M.marinum_M AARTERLQRFLAQVL-----------------------------------
MAV_0058|M.avium_104 AAETERLQRFLSQVL-----------------------------------
MUL_3658|M.ulcerans_Agy99 APTNAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVT
MLBr_00669|M.leprae_Br4923 MDR-----------------------------------------------
Mb0074|M.bovis_AF2122/97 QAGEVLFEQSTMGDLIYVVSEGEFEIVHDWPTAVRNWSRLPGRG------
Rv0073|M.tuberculosis_H37Rv QAGEVLFEQSTMGDLIYVVSEGEFEIVHELADGGEELVKVAGPGDYFGEI
MSMEG_5316|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4704|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3165|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3050|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
MUL_3658|M.ulcerans_Agy99 RAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVR
MLBr_00669|M.leprae_Br4923 --------------------------------------------------
Mb0074|M.bovis_AF2122/97 ----------ITSAR-----------------------------------
Rv0073|M.tuberculosis_H37Rv GVLFHLPRSATVRARSDATAVGYTVQAFRERLGVGGLRDLIEHRALAND-
MSMEG_5316|M.smegmatis_MC2_155 ---------------------------------
Mvan_4704|M.vanbaalenii_PYR-1 ---------------------------------
Mflv_3165|M.gilvum_PYR-GCK ---------------------------------
MAB_3050|M.abscessus_ATCC_1997 ---------------------------------
TH_1784|M.thermoresistible__bu ---------------------------------
MMAR_0060|M.marinum_M ---------------------------------
MAV_0058|M.avium_104 ---------------------------------
MUL_3658|M.ulcerans_Agy99 ATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGGQ
MLBr_00669|M.leprae_Br4923 ---------------------------------
Mb0074|M.bovis_AF2122/97 ---------------------------------
Rv0073|M.tuberculosis_H37Rv ---------------------------------