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TSLELEGGGAADFSAGEVYFVGNATTVIRFCGISILTDPAFLHKGEHVYLGHGIWARREVEPACQIADLP PIDLVVLSHYHGDHFDDVAAEQLDKNLPIVSTADAIEKLSPLGFTQGHALSTWESLEVRKGEATLTITAM PAKHATDGAVNAMLMPVNGHLLDFSRGGEQLYRLYITGDTMLVEDLHEIPRRYSAIDLGLIHTGGTTFLV TVVTMTGEQGVRAVEITKPRVAIPIHYNDFSVFLSGLDDFQKAAQTSGAATEFVYLTHGDTYTFEPGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5109 | - | - | 100% (279) | hypothetical protein MSMEG_5109 |
| M. smegmatis MC2 155 | MSMEG_6233 | - | 5e-59 | 42.70% (267) | hypothetical protein MSMEG_6233 |
| M. smegmatis MC2 155 | MSMEG_5509 | - | 4e-12 | 26.21% (248) | hypothetical protein MSMEG_5509 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0930 | - | 1e-09 | 26.14% (241) | hypothetical protein Mb0930 |
| M. gilvum PYR-GCK | Mflv_2585 | - | 3e-61 | 45.83% (264) | protein Pfam: Lactamase_B |
| M. tuberculosis H37Rv | Rv0906 | - | 1e-09 | 26.14% (241) | hypothetical protein Rv0906 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0960 | - | 1e-06 | 22.36% (246) | hypothetical protein MAB_0960 |
| M. marinum M | MMAR_4624 | - | 2e-10 | 27.80% (241) | hypothetical protein MMAR_4624 |
| M. avium 104 | MAV_1029 | - | 5e-11 | 27.50% (240) | metallo-beta-lactamase family protein |
| M. thermoresistible (build 8) | TH_0095 | - | 3e-10 | 28.46% (246) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0235 | - | 1e-10 | 27.80% (241) | hypothetical protein MUL_0235 |
| M. vanbaalenii PYR-1 | Mvan_4991 | - | 2e-06 | 23.21% (224) | hypothetical protein Mvan_4991 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0095|M.thermoresistible__bu MSRSWLGLMRQAAGVATVLGGGWLIRALRGAPAAVGADRRDIRPVAQRSP
Mvan_4991|M.vanbaalenii_PYR-1 --MEVRTALRFGFGTASLFAGGWVLRALQGTPAALGATPPEIAPVARRSP
Mb0930|M.bovis_AF2122/97 ---MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSP
Rv0906|M.tuberculosis_H37Rv ---MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSP
MMAR_4624|M.marinum_M ---MVGRALRLAAGTASLAAGGWLMRALHGAPAALGADPAAIEAASDGSP
MUL_0235|M.ulcerans_Agy99 ---MVGRALRLAAGTASLAAGGWLMRALRGAPAALGADPAAIEAASDGSP
MAV_1029|M.avium_104 ----MRGTLRLVAGTASLAAGGWLVRALHGAPDALGADPASIAAVTSGSP
MAB_0960|M.abscessus_ATCC_1997 -----MRALWVGAGAA--IASTWIGRALRDVPQTLGASKGRIAEVAKGSP
MSMEG_5109|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2585|M.gilvum_PYR-GCK --------------------------------------------------
TH_0095|M.thermoresistible__bu NYRDGAFVNLDPASMISLDRQQQWVLAREFLDGRAATRPAAPIPLVTPNP
Mvan_4991|M.vanbaalenii_PYR-1 HYQDGKFVNLEPPSGITMDRDLQRMLLRDLANFASQGTPPGPIPLADPPV
Mb0930|M.bovis_AF2122/97 NYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRPAAPIPLASPNI
Rv0906|M.tuberculosis_H37Rv NYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRPAAPIPLASPNI
MMAR_4624|M.marinum_M NYRDGVFVNLDPASVFTLNREEMRLLAWELLANRGGSRPAKPIPLAAPQV
MUL_0235|M.ulcerans_Agy99 YYRDGVFVNLDPASVFTLNREEMRLLAWELLANRGGSRPAKPIPLAAPQV
MAV_1029|M.avium_104 HFRDGAFVNLEPASEIKMDREQLRLIAWELIANRGGSRPPAAIPLASPGV
MAB_0960|M.abscessus_ATCC_1997 QYRGGTFHNAEPARQFSPDAET-TTVVWDVLTRRGVGTPKGQVPLAVPEL
MSMEG_5109|M.smegmatis_MC2_155 ---------------------------------------MTSLELEGGGA
Mflv_2585|M.gilvum_PYR-GCK ------------------------------------------MQID----
: :
TH_0095|M.thermoresistible__bu ADHGVGAADLAVRWYGHSTAMVEVDGYRVLTDPIWSRRCSPSALVG---P
Mvan_4991|M.vanbaalenii_PYR-1 VDP--TPAPAAASWYGHSSTLIEVDGYRVLADPVWSNRCSPSRAVG---P
Mb0930|M.bovis_AF2122/97 YRG--DASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVG---P
Rv0906|M.tuberculosis_H37Rv YRG--DASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVG---P
MMAR_4624|M.marinum_M YQG--DASRLAVSWFGHSTAMVEIDGYRVLTDPVWSDRCSPSDLVG---P
MUL_0235|M.ulcerans_Agy99 YQG--DASRLAVSWFGHSTAMVEIDGYRVLTDPVWSDRCSPSDLVG---P
MAV_1029|M.avium_104 VDA--DPSRLAVSWFGHSTALLEIDGYRVLTDPVWSERCSPSDIVG---P
MAB_0960|M.abscessus_ATCC_1997 SGP---PADLAATWFGHSSVLVEIDGYRVLTDPVWSDRCSPSRVVG---P
MSMEG_5109|M.smegmatis_MC2_155 ADF----SAGEVYFVGNATTVIRFCGISILTDPAFLHKGEHVYLGHGIWA
Mflv_2585|M.gilvum_PYR-GCK -----------VTFIGTATTLIRCGNITVLTDPNFLHRGQRAYLGYGLWS
. : * ::.::. . :*:** : : . .
TH_0095|M.thermoresistible__bu RRLHEPPTPLEALPAVDAVLISHDHYDHLDMDTVVRLARTQRAPFLVPLG
Mvan_4991|M.vanbaalenii_PYR-1 QRMHDVPVLIEALPAVDAVIISHDHYDHLDIDTIVALAHTQRAPFVVPLG
Mb0930|M.bovis_AF2122/97 QRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLG
Rv0906|M.tuberculosis_H37Rv QRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLG
MMAR_4624|M.marinum_M QRLHPPPVQLDGLPAVDAVVISHDHYDHLDIDTVIALVRSQRAPFFVPLG
MUL_0235|M.ulcerans_Agy99 QRLHPPPVQLDGLPAVDAVVISHDHYDHLDIDTVIALVRSQRAPFFVPLG
MAV_1029|M.avium_104 QRLHPPPIQLEGLPAVDAVVISHDHYDHLDIDTVRALARTQRAPFFVPLG
MAB_0960|M.abscessus_ATCC_1997 HRQHPVPVELSALPALDAVVISHDHYDHLDMDSIIALTRSQNAVFVVPLG
MSMEG_5109|M.smegmatis_MC2_155 RREVEPACQIADLPPIDLVVLSHYHGDHFDDVAAEQLDKNLPIVSTADAI
Mflv_2585|M.gilvum_PYR-GCK KRRRAPGLTPEELPPIDAIVLSHMHGDHWDRVAERSLDRELPVITTHEAA
:* **.:* :::** * ** * : *
TH_0095|M.thermoresistible__bu VGAHLRTWRIPEHRIVELDWYESRRIGDLRITCTPARHFSG----RLFAR
Mvan_4991|M.vanbaalenii_PYR-1 IGAHLRKWGIPESRIVELDWNEAHRIGDLTLICTPARHFSG----RLFAR
Mb0930|M.bovis_AF2122/97 VGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSG----RFLSR
Rv0906|M.tuberculosis_H37Rv VGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSG----RFLSR
MMAR_4624|M.marinum_M VGAHLRSWGVPEDRIIELDWHQSAQVGELSVICMPARHFSG----RFMSR
MUL_0235|M.ulcerans_Agy99 VGAHLRSWGVPEDRIIEFDWHQSAQVGELSVICMPARHFSG----RFMSR
MAV_1029|M.avium_104 VGAHLRRWGIPEQRIVELDWHQSGKVDELTVTCVPARHFSG----RFLDR
MAB_0960|M.abscessus_ATCC_1997 VGAHLRGWGVSPARVIELDWDQSHQLGKLTLTCTQARHFSG----RSITR
MSMEG_5109|M.smegmatis_MC2_155 EKLSPLGFTQGHALSTWESLEVRKGEATLTITAMPAKHATDGAVNAMLMP
Mflv_2585|M.gilvum_PYR-GCK KALHRKGFTEAVGLSTWDPFVLTKDGETLTVTAMPGRHAPT-PVSRLLPP
: * : . .:* . :
TH_0095|M.thermoresistible__bu NTTLWASWVIAG--PRHRAFFGGDTGYTKSFTEIGVDHGPFDLTLLPIGA
Mvan_4991|M.vanbaalenii_PYR-1 DSTLWSSWVVTG--PTHKAFFGGDTGYTKSFAEIGAEHGPFDLTLLPIGA
Mb0930|M.bovis_AF2122/97 NTTLWASWAFVG--PNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGA
Rv0906|M.tuberculosis_H37Rv NTTLWASWAFVG--PNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGA
MMAR_4624|M.marinum_M NNTLWASWAFVG--PTHRAYFGGDTGYTKSFAEIGADHGPFDLTLMPIGA
MUL_0235|M.ulcerans_Agy99 NNTLWASWAFVG--PTHRAYFGGDTGYTKSFAEIGADHGPFDLTLMPIGA
MAV_1029|M.avium_104 NTTLWASWALAG--PTHRAYFGGDTGYTKTFAQTGAEHGPFDLTLLPIGA
MAB_0960|M.abscessus_ATCC_1997 NTTLWASWAFAG--PKHKVFFGGDTGYTKAFKVIGDTYGPFDLTLLPVGA
MSMEG_5109|M.smegmatis_MC2_155 VNGHLLDFSRGG-EQLYRLYITGDTMLVEDLHEIPRRYSAIDLGLIHTGG
Mflv_2585|M.gilvum_PYR-GCK VMGSMLDFDSGGGSSRRRVYISGDTLLIDELDEIPVRFNAIDAGVLHLGG
.: * : :: *** . : ...:* :: *.
TH_0095|M.thermoresistible__bu YHPAWPD----IHMNPEEAVRAHLDMAEADSGLLVPIHWATFRLAPHPWS
Mvan_4991|M.vanbaalenii_PYR-1 YHPAFAD----IHMNPEEAVRAHLDLADVDNSLMVPIHWATFRLAPHPWA
Mb0930|M.bovis_AF2122/97 YNTAWPD----IHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWG
Rv0906|M.tuberculosis_H37Rv YNTAWPD----IHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWG
MMAR_4624|M.marinum_M YNTGWPD----IHMNPEEAVRAHLDVSDTGSGLLVPIHWGTFRLAPHPWA
MUL_0235|M.ulcerans_Agy99 YSTGWPD----IHMNPEEAVRAHLDVSDTGSGLLVPIHWGTFRLAPHPWA
MAV_1029|M.avium_104 YNTAWPD----VHMNPEEAVRAHRDVTN--DGLLVPIHWGTFRLAPHPWA
MAB_0960|M.abscessus_ATCC_1997 YNTSWAD----IHMNPEEAVQTHLDLAT-AQAPLLPIHWATFNLALHPWA
MSMEG_5109|M.smegmatis_MC2_155 TTFLV-------TVVTMTGEQGVRAVEITKPRVAIPIHYNDFSVFLSGLD
Mflv_2585|M.gilvum_PYR-GCK TRLPFGDRLPVGLTVTMDGRQGAETVERLHLPRVIPVHFDDYRVFASPLA
. . : : :*:*: : :
TH_0095|M.thermoresistible__bu EPVERLLAAADPARVPVAVPRPGERVDRDSAGASDQWWRPADGR
Mvan_4991|M.vanbaalenii_PYR-1 EPAERLLTAADAERVRVAVPMPGQRVVPEST--FDPWWRF----
Mb0930|M.bovis_AF2122/97 EPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWRL----
Rv0906|M.tuberculosis_H37Rv EPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWRL----
MMAR_4624|M.marinum_M EPVERLLKAAESDQVQVAVPLPGQRIDPAGPLRFNPWWRL----
MUL_0235|M.ulcerans_Agy99 EPVERLLKAAESDQVQVAVPLPGQGVDPAGPLRFNPWWRL----
MAV_1029|M.avium_104 EPVERLLAAAEPAKVKVAVPVPGQRIDPAAPQKPDPWWRL----
MAB_0960|M.abscessus_ATCC_1997 EPIERVLAAAEEQGVTVVAPRPGQRADARQPAAPDGWWRLT---
MSMEG_5109|M.smegmatis_MC2_155 DFQKAAQTSGAATEFVYLTHGDTYTFEPGA--------------
Mflv_2585|M.gilvum_PYR-GCK DFHREMSRRGLADRVVTVERGQTVSL------------------
: . . .