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SVVCSNLSFSWPDDTVLFSDLSFSLGPGRTGLVAPNGAGKSTLLKLIAGEYRPTAGSVSVDGTVGYLPQS LPFTGDLTVAAVLGIAPVLDALTALAAGDASDDVFTTIGDDWDIEERSRAQLDRLGLDTVALDRRLDTLS GGEVVSLGLAAQLLKRPEVLMLDEPTNNLDSAARQRFYDALDGYSGCLLVVSHDRALLDRMDQIAELYRG EVVFYGGNFTAYRETVEANQRAAESSIRNAEQQLKREKRQMQEARERAARRSSAAARNLKDAGLPKIVAG KLKRDAQESAAKSDDVHAKRVDAARARLEDAERALRDDKVIVLDLPDTEVPAGRTLFTGTGLQISRGGRN LFADNGIDVSIRGPERIALTGSNGAGKSTLLRIIDGQLKPDGGTCQQADGRVAYLSQRLDLLDLDRSVAE SLAASAPSLTHTRRMHLLAQFLFRGDRIHLPVGALSGGERLRATLACVLFAEPAPQLLLLDEPTNNLDLV SVGQLESALNAYRGAFVVVSHDERFLDTIGIERRWHLEDGRLRVTAAAG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_5102 | - | - | 100% (540) | ABC transporter ATP-binding protein |
M. smegmatis MC2 155 | MSMEG_6748 | - | 7e-61 | 33.33% (564) | ABC transporter ATPase |
M. smegmatis MC2 155 | MSMEG_3140 | - | 5e-57 | 32.91% (550) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1508 | - | 3e-56 | 34.69% (539) | macrolide ABC transporter ATP-binding protein |
M. gilvum PYR-GCK | Mflv_2181 | - | 0.0 | 67.85% (535) | ABC transporter related |
M. tuberculosis H37Rv | Rv1473 | - | 3e-56 | 34.69% (539) | macrolide ABC transporter ATP-binding protein |
M. leprae Br4923 | MLBr_01248 | - | 9e-51 | 31.21% (535) | putative ABC transporter ATP-binding protein |
M. abscessus ATCC 19977 | MAB_1846 | - | 1e-126 | 48.55% (519) | putative ABC transporter ATP-binding protein |
M. marinum M | MMAR_2279 | - | 2e-55 | 33.65% (532) | ATP-binding protein ABC transporter |
M. avium 104 | MAV_3306 | - | 7e-58 | 34.50% (542) | ABC transporter ATP-binding protein |
M. thermoresistible (build 8) | TH_3711 | - | 0.0 | 68.67% (533) | PUTATIVE ABC transporter ATP-binding protein |
M. ulcerans Agy99 | MUL_1481 | - | 3e-56 | 33.83% (532) | ATP-binding protein ABC transporter |
M. vanbaalenii PYR-1 | Mvan_4514 | - | 0.0 | 70.49% (532) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_5102|M.smegmatis_MC2_155 ----------------------------MSVVCSNLSFSW---PDDTVLF TH_3711|M.thermoresistible__bu ----------------------------MSIVFSDVSFAW---PDGTALF Mflv_2181|M.gilvum_PYR-GCK MTPALPWNTCSRTEEPAPCPHLAESFRMPSITCTHLSYSFDAGPATAPLF Mvan_4514|M.vanbaalenii_PYR-1 ---------------------------MSSVVCSHLSFSW---PDDTPLF MAB_1846|M.abscessus_ATCC_1997 --------------------------MSAVISCGALTYTH---PDGSVAL MMAR_2279|M.marinum_M -----------------------------MITATDLEVRAG--ARILLSP MUL_1481|M.ulcerans_Agy99 -----------------------------MITATDVEVRAG--ARILLSP MAV_3306|M.avium_104 -----------------------------MITATDLEVRAG--ARILLSP Mb1508|M.bovis_AF2122/97 -----------------------------MITATDLEVRAG--ARILLAP Rv1473|M.tuberculosis_H37Rv -----------------------------MITATDLEVRAG--ARILLAP MLBr_01248|M.leprae_Br4923 -------------------------MAEFIYTMKKVRKAHG----DKVIL : MSMEG_5102|M.smegmatis_MC2_155 SDLSFSLGPG-RTGLVAPNGAGKSTLLKLIAGEYRPTAG--SVSVDGTVG TH_3711|M.thermoresistible__bu TDLSFTIGPG-RTGLVAPNGAGKSTLLDLIAGARRPTSG--SVTVDGTVG Mflv_2181|M.gilvum_PYR-GCK ADLTFSAGPG-RTGLVGSNGSGKSTLLRLIAGELSPTAG--AVTVDGVIG Mvan_4514|M.vanbaalenii_PYR-1 TDLSFTVGAG-RTGLVAANGAGKSTLLRLIAGELTATTG--AVTADGVVG MAB_1846|M.abscessus_ATCC_1997 DGLDMLVPAG-RSGLVGVNGSGKSTLLKLIAGELRPTSG--MVHASGEIG MMAR_2279|M.marinum_M DGPDLRVQPGDRIGLVGRNGAGKTTTLRILAGESEPYAG--SVTRAGEIG MUL_1481|M.ulcerans_Agy99 DGPDLRVQPGDRIGLVGRNGAGKTTTLRILAGESEPYAG--SVTRAGEIG MAV_3306|M.avium_104 DGPDLRVQPGDRIGLVGRNGAGKTTTLRILAGETEPYAG--TIARSGEIG Mb1508|M.bovis_AF2122/97 DGPDLRVQPGDRIGLVGRNGAGKTTTLRILAGEVEPYAG--SVTRAGEIG Rv1473|M.tuberculosis_H37Rv DGPDLRVQPGDRIGLVGRNGAGKTTTLRILAGEVEPYAG--SVTRAGEIG MLBr_01248|M.leprae_Br4923 DDVTLNFFPGAKIGVVGPNGAGKSSVLRIMAGMDKPNNGDAFLATGASVG . : .* : *:*. **:**:: * ::** . * : . :* MSMEG_5102|M.smegmatis_MC2_155 YLPQS-----LPFTGDLTVAAVLGIAPVLDALT-------ALAAGDASDD TH_3711|M.thermoresistible__bu HLPQH-----LPFMPEATVGDVLGITPVLTALD-------ALAAGDASEA Mflv_2181|M.gilvum_PYR-GCK HLPQT-----LPMRDDRRVAEVLGVAEAIDALN-------ALSDGDSRDT Mvan_4514|M.vanbaalenii_PYR-1 YLPQT-----LPLLDDRSVADVLGVAAVIDALN-------ALAAGDPSAH MAB_1846|M.abscessus_ATCC_1997 YLPQD-----LTIRADQSVPDLLGLTPVLAAIE-------AIENGSTDQT MMAR_2279|M.marinum_M YLPQDPKEGDLEVLARDRVLSARGLDVLLTDLEKQQALMAEVADDAARDR MUL_1481|M.ulcerans_Agy99 YLPQDPKEGDLEVLARDRVLSARGLDVLLTDLEKQQALMAEVADDAARDR MAV_3306|M.avium_104 YLPQDPKEGDLDVLARDRVLSARGLDVLLTDLEKQQALMAEVADDDARDR Mb1508|M.bovis_AF2122/97 YLPQDPKVGDLDVLARDRVLSARGLDVLLTDLEKQQALMAEVADEDERDR Rv1473|M.tuberculosis_H37Rv YLPQDPKVGDLDVLARDRVLSARGLDVLLTDLEKQQALMAEVADEDERDR MLBr_01248|M.leprae_Br4923 ILQQEPPLNEEKTVRGNVEEGLGDIKIKLDRFS----EVAELMATDSSSE * * .: : : : MSMEG_5102|M.smegmatis_MC2_155 VFTTIG---------DDWDIEERSRAQLDRLGLDTVALDRRLDTLSGGEV TH_3711|M.thermoresistible__bu VFAAIG---------DDWDVEERCRGMLDRLGLGEVAVDRRLGSLSGGEV Mflv_2181|M.gilvum_PYR-GCK VFAAIG---------DDWDVEERTRAQLDRLGLGHVALDRSLRSLSGGEV Mvan_4514|M.vanbaalenii_PYR-1 HFAMIG---------DDWDVEERTRAQLDRLGLGHIGLDRSLRSLSGGEV MAB_1846|M.abscessus_ATCC_1997 DFDTVG---------DDWDLAERVRAELDRLGLPAAVLDRSLGELSGGEV MMAR_2279|M.marinum_M AIRRYGQLEERFVALGGYGAESEASRICASLGLPERVLTQQLRTLSGGQR MUL_1481|M.ulcerans_Agy99 AIRRYGQLEERFVTLGGYGAESEASRICASLGLPERVLTQQLRTLSGGQR MAV_3306|M.avium_104 AIRRYGQLEERFVALGGYGAESEASRICASLGLPERVLTQQLRTLSGGQR Mb1508|M.bovis_AF2122/97 AIRRYGQLEERFVALGGYGAESEAGRICASLGLPERVLTQRLRTLSGGQR Rv1473|M.tuberculosis_H37Rv AIRRYGQLEERFVALGGYGAESEAGRICASLGLPERVLTQRLRTLSGGQR MLBr_01248|M.leprae_Br4923 LMEEMGRLQEELDHADAWDLDSQLEQAMDVLRCPP--PDEPVTNLSGGER : * . :. .. * . : ****: MSMEG_5102|M.smegmatis_MC2_155 VSLGLAAQLLKRPE----------VLMLDEPTNNLDSAARQRFYDALDGY TH_3711|M.thermoresistible__bu VAVGLAAQLLRRPE----------VLLLDEPTNNLDADARRRLHAALDDY Mflv_2181|M.gilvum_PYR-GCK VTLGLARELLRRPD----------VLLLDEPTNNLDADARGKLCDALDDF Mvan_4514|M.vanbaalenii_PYR-1 VSLGLARELLRRPD----------VLLLDEPTNNLDADARHRLYDALDDF MAB_1846|M.abscessus_ATCC_1997 IRLGLARLLLRRPD----------VLLLDEPTNNLDGESRRHLYDVVSAW MMAR_2279|M.marinum_M RRVELARILFAASD---TGAGSSTVLLLDEPTNHLDADSVGWLRDFLRAH MUL_1481|M.ulcerans_Agy99 RRVELARILFAASD---TGAGSSTVLLLDEPTNHLDADSVGWLRDFLRAH MAV_3306|M.avium_104 RRVELARILFAAAEGGATGSGSATTLLLDEPTNHLDADSIGWLRDFLRAH Mb1508|M.bovis_AF2122/97 RRVELARILFAASE---SGAGNSTTLLLDEPTNHLDADSLGWLRDFLRLH Rv1473|M.tuberculosis_H37Rv RRVELARILFAASE---SGAGNSTTLLLDEPTNHLDADSLGWLRDFLRLH MLBr_01248|M.leprae_Br4923 RRVALCKLLLSKPD----------LLLLDEPTNHLDAESVQWLEQHLAGY : *. *: .: *:******:**. : : : MSMEG_5102|M.smegmatis_MC2_155 SGCLLVVSHDRALLDRMDQ---IAELYRGEVVFYGGNFTAYRETVEANQR TH_3711|M.thermoresistible__bu PGTLLVVSHDRVLLDRMER---IAELYRGEMLFYGGNFTTYQRQLAADQQ Mflv_2181|M.gilvum_PYR-GCK TGCLLLVSHDRMLLDRMDR---IAELDRGEVVLYGGNFTAYQGAVADAQR Mvan_4514|M.vanbaalenii_PYR-1 GGCLLVVSHDRVLLDRMDR---IAELYRGQVRFYGGNFTAYQDAVTDAQR MAB_1846|M.abscessus_ATCC_1997 QRTLLVVSHDRELLEHVER---IGDLRDGGVTWYGGGYSDYAAAVAAEQE MMAR_2279|M.marinum_M TGGLIIISHNVELLADVVNRVWFLDAVRGEVDVYNMGWHKYLDARATDEQ MUL_1481|M.ulcerans_Agy99 TGGLIIISHNVELLADVVNRVWFLDAVRGEVDVYNMGWHKYLDARATDEQ MAV_3306|M.avium_104 TGGLVIISHNVELLADVVNRVWFLDAVRGEVDVYNMSWQKYLDARATDEQ Mb1508|M.bovis_AF2122/97 TGGLVVISHNVDLVADVVNKVWFLDAVRGQVDVYNMGWQRYVDARATDEQ Rv1473|M.tuberculosis_H37Rv TGGLVVISHNVDLVADVVNKVWFLDAVRGQVDVYNMGWQRYVDARATDEQ MLBr_01248|M.leprae_Br4923 AGAVLAVTHDRYFLDNVAE--WILELDRGRAYPYEGNYSTYLEKKAERLT :: ::*: :: : . : : * * .: * MSMEG_5102|M.smegmatis_MC2_155 AAESSIRNAEQQLKREKRQMQEARERAARRSSAAARNLKDAGLPKIVAGK TH_3711|M.thermoresistible__bu SARNDVRHAEQSLRREKRERQQARERAARRSGTAARTVKDAGLPRIVAGA Mflv_2181|M.gilvum_PYR-GCK AARDTVRNAEQTIKREQRQRQQARERADRRSGNAARTLKDAGLPKIVAGA Mvan_4514|M.vanbaalenii_PYR-1 AAQDAVRSAEQLLRREKHQRQQARERADRRAGTAARTLGDAGLPKIVAGA MAB_1846|M.abscessus_ATCC_1997 AAAQAISTAKAEVRRERRDLAEAERVIAQRRRYGAKMQANKREPKIVMGL MMAR_2279|M.marinum_M --------------RRRRERANAERKATALRTQAAKMGAKATKAVAAQNM MUL_1481|M.ulcerans_Agy99 --------------RRRRERANAERKATALRTQAAKMGAKATKAVAAQNM MAV_3306|M.avium_104 --------------RRRRERANAERKAAALRTQAAKLGAKATKAVAAQNM Mb1508|M.bovis_AF2122/97 --------------RRIRERANAERKAAALRAQAAKLGAKATKAVAAQNM Rv1473|M.tuberculosis_H37Rv --------------RRIRERANAERKAAALRAQAAKLGAKATKAVAAQNM MLBr_01248|M.leprae_Br4923 -----------------TQGRKDAKLQKRLTDELAWVRSGAKARQAKSKA : : . * MSMEG_5102|M.smegmatis_MC2_155 LKRDAQESAAKSDDVHAKRVDAARARLEDAERALRDDKVIVLDLPDTEVP TH_3711|M.thermoresistible__bu MKRRAQESAGRTDEVRAARIAAGRARLEEAEKRLRDDDAMVLDLPDTTVP Mflv_2181|M.gilvum_PYR-GCK RKRRAQESAARADDVHARRIDEAKLRLVSAERAVRDDDELALQLPATTVA Mvan_4514|M.vanbaalenii_PYR-1 RKRRAQETAGRSDDVHASRVDDARSRLEDAERAVRDDDALVLELPGTLVP MAB_1846|M.abscessus_ATCC_1997 RKRAAQESAAALKQTQTDRLDKARENLGEAQTRLRADRSIRIDLPGTEVP MMAR_2279|M.marinum_M LRRADRMMAALDEERVADKVARIKF--------------------PTPAA MUL_1481|M.ulcerans_Agy99 LRRADRMMAALDEERVADKVARIKF--------------------PTPAA MAV_3306|M.avium_104 LRRADRMMAALDEERVADKVARIKF--------------------PTPAA Mb1508|M.bovis_AF2122/97 LRRADRMMAALDEERVADKVARIKF--------------------PTPAA Rv1473|M.tuberculosis_H37Rv LRRADRMMAALDEERVADKVARIKF--------------------PTPAA MLBr_01248|M.leprae_Br4923 RLQRYEEMAAEAEKNRKFDFEEIQIP--------------------VGPR : . *. .. . : . MSMEG_5102|M.smegmatis_MC2_155 AGRTLFTGTGLQISRGGRNLFADNGIDVSIRGPERIALTGSNGAGKSTLL TH_3711|M.thermoresistible__bu AGRTVFAGSGLTVGNVLR------GIDLTVRGPERIALTGANGVGKTTLL Mflv_2181|M.gilvum_PYR-GCK AGRTVLQASALQVDRGGRTLLA--GVDLTIRGPERIALTGRNGAGKTTLL Mvan_4514|M.vanbaalenii_PYR-1 SARMVLRLNGIRVRRNGCDVLD--GIDLTVRGPERIALTGPNGAGKTTLL MAB_1846|M.abscessus_ATCC_1997 AGRVVLTTEQLVLRHGVP-------AHLDLRGPQRVGLVGPNGSGKTTLL MMAR_2279|M.marinum_M CGRVPLVVKGLSKTYGSLEVFT--GVDLAIDRGSRVVVLGLNGAGKTTLL MUL_1481|M.ulcerans_Agy99 CGRVPLVVKGLSKTYGSLEVFT--GVDLAIDRGSRVVVLGLNGAGKTTLL MAV_3306|M.avium_104 CGRTPLTATGLSKSYGSLEVFS--GVDLAIDRGSRVVVLGLNGAGKTTLL Mb1508|M.bovis_AF2122/97 CGRTPLVANGLGKTYGSLEVFT--GVDLAIDRGSRVVILGLNGAGKTTLL Rv1473|M.tuberculosis_H37Rv CGRTPLVANGLGKTYGSLEVFT--GVDLAIDRGSRVVILGLNGAGKTTLL MLBr_01248|M.leprae_Br4923 LGNMVVEVEHLDKGYGGRTLIK--DLSFTLPRNGIVGIIGPNGVGKTTLF .. . : . : : : * ** **:**: MSMEG_5102|M.smegmatis_MC2_155 RIIDGQLKPDGGTCQQADGR-VAYLSQRLDLLDLDRSVAESLAASAPSLT TH_3711|M.thermoresistible__bu RVIGGRLAPDAGTVTRADGR-IAYLSQRLDLLDPGQTVLDNLAEFAPTLS Mflv_2181|M.gilvum_PYR-GCK RTLRGDVVPDAGTVQVADGR-VAYLSQRLDLLDDDRTLSDNLAMSAPTLS Mvan_4514|M.vanbaalenii_PYR-1 RTLLGEIEPDAGAVEVADGR-VAYLSQRLDLLDEDRSVAENLAAFAPSLT MAB_1846|M.abscessus_ATCC_1997 HTIAGRIPAAEGSATVHVP--LGLLPQRLDLLDDSLSVADNVARRAPHAD MMAR_2279|M.marinum_M RLLAGVEHPDTGGLEPGHGLRIGYFAQEHDTLDNDATVWENIRHAAPESG MUL_1481|M.ulcerans_Agy99 RLLAGVEHPDTGGLEPGHGLRIGYFAQEHDTLDNDATVWENIRHAAPESG MAV_3306|M.avium_104 RLLAGAETPDTGRIEPGHGLRIGYFAQEHDTLDNDATVWQNIRHAAPDSG Mb1508|M.bovis_AF2122/97 RLLAGVEQPDTGVLEPGYGLRIGYFAQEHDTLDNDATVWENVRHAAPDAG Rv1473|M.tuberculosis_H37Rv RLLAGVEQPDTGVLEPGYGLRIGYFAQEHDTLDNDATVWENVRHAAPDAG MLBr_01248|M.leprae_Br4923 KTIVGLEQPDGGAVKIGETVKLSYVDQTRAGIDPKKIVWEVVSDGLDHIQ : : * . * :. . * :* : : : MSMEG_5102|M.smegmatis_MC2_155 H----TRRMHLLAQFLFRGDRIHLPVGALSGGERLRATLACVLFAEPAPQ TH_3711|M.thermoresistible__bu V----TGRRHLLARFLFDDKRIALPIRALSGGERLRATLACVLHAEPAPQ Mflv_2181|M.gilvum_PYR-GCK V----TRRRHLLAQFLFRGDAVDLPVRALSGGERLRATLACVLFSEPAPH Mvan_4514|M.vanbaalenii_PYR-1 V----TRRRHLLAQFLFRGDAVERPVRVLSGGERLRATLACVLYAEPAPQ MAB_1846|M.abscessus_ATCC_1997 V----NAVRARLARFLFRGNAADKLVGALSGGERFRATLAAVLLADPAPQ MMAR_2279|M.marinum_M E----QELRGLLGAFMFTGPQLDQPAGTLSGGEKTRLALAGLVASTAN-- MUL_1481|M.ulcerans_Agy99 E----QELRGLLGAFMFTGPQLDQPAGTLSGGEKTRLALAGLVASTAN-- MAV_3306|M.avium_104 E----QDLRGLLGAFMFSGPQLDQPAGTLSGGEKTRLALAGLVASTAN-- Mb1508|M.bovis_AF2122/97 E----QDLRGLLGAFMFTGPQLEQPAGTLSGGEKTRLALAGLVASTAN-- Rv1473|M.tuberculosis_H37Rv E----QDLRGLLGAFMFTGPQLEQPAGTLSGGEKTRLALAGLVASTAN-- MLBr_01248|M.leprae_Br4923 VGQTEVSSRAYVSAFGFKGPDQQKLAGVLSGGERNRLNLALTLKQGGN-- :. * * . .*****: * ** : MSMEG_5102|M.smegmatis_MC2_155 LLLLDEPTNNLDLVSVGQLESALNAYRGAFVVVSHDERFLDTIGIERRWH TH_3711|M.thermoresistible__bu LLLLDEPTNNLDLTSIAQLESALIAYRGAFIVVSHDDRFVAAIGVNRRLR Mflv_2181|M.gilvum_PYR-GCK LLLLDEPTNNLDLAGIAQLESALVAYRGAFIVVSHDAPFLDAIAVDRVVH Mvan_4514|M.vanbaalenii_PYR-1 LLLLDEPTNNLDLVSVGQLESALAAYRGAFIVVSHDASFLDAIGVDRVLR MAB_1846|M.abscessus_ATCC_1997 LLLLDEPTNNLDFASYDALVSALAEYRGAVLVASHDLGFLEDIGAAQVDW MMAR_2279|M.marinum_M VLLLDEPTNNLDPASREQVLDALRSYQGAVVLVTHDPGAAEALDPQRVVL MUL_1481|M.ulcerans_Agy99 VLLLDEPTNNLDPASREQVLDALRSYQGAVVLVTHDPGAAEALDPQRVVL MAV_3306|M.avium_104 VLLLDEPTNNLDPASREQVLDALRSYTGAVVLVTHDPGAAEALDPQRVVL Mb1508|M.bovis_AF2122/97 VLLLDEPTNNLDPASREQVLDALRSYRGAVVLVTHDPGAAAALGPQRVVL Rv1473|M.tuberculosis_H37Rv VLLLDEPTNNLDPASREQVLDALRSYRGAVVLVTHDPGAAAALGPQRVVL MLBr_01248|M.leprae_Br4923 LILLDEPTNDLDVETLGSLENALVNFPGCAVVISHDRWFLDRTCTHILAW ::*******:** : .** : *. :: :** MSMEG_5102|M.smegmatis_MC2_155 LEDGRLRVTAAAG------------------------------- TH_3711|M.thermoresistible__bu LSDGKLS------------------------------------- Mflv_2181|M.gilvum_PYR-GCK LAGGRLAEV----------------------------------- Mvan_4514|M.vanbaalenii_PYR-1 LADSTLAPG----------------------------------- MAB_1846|M.abscessus_ATCC_1997 RPDPVIG------------------------------------- MMAR_2279|M.marinum_M LPDATEDYWSDEYRDLIELA------------------------ MUL_1481|M.ulcerans_Agy99 LPDATEDYWSDEYRDLIELA------------------------ MAV_3306|M.avium_104 LPDGTEDYWSDEYRDLIELA------------------------ Mb1508|M.bovis_AF2122/97 LPDGTEDYWSDEYRDLIELA------------------------ Rv1473|M.tuberculosis_H37Rv LPDGTEDYWSDEYRDLIELA------------------------ MLBr_01248|M.leprae_Br4923 EGDDEGKWFWFEGNFGAYEENKVERLGAEAARPHRVTHRKLTRD .