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GTMTATLVAKNVAGGFAHRTLFEGLDLTVARGDVIGVVGANGAGKSTLLRILAGDLDPLEGAVSVAPADA FVGWLPQEHERVPGETVAAYVARRAGCADATSAMEAAAAALADPTSNADPAVDPAEAYSAALDHWLATGA ADLDERLPAVLADLGLDTEMVRPDSTLMTALSGGQAARVGLAALLVSRFDIVLLDEPTNDLDLDGLDRLE AFVRDLRGGVVLVSHDREFLARSVTGVLELDLAQNTNTLYGGGYDSYLEEREVNRRHKREQYDEFAEKKA DLVARARVQREWSSQGVRNAIRKAPDNDKIRRRAATESSEKQAQKVRQMESRIARLEEVEEPRKEWVLQF SIGAAPRSSTVVATLDNAVVRQGNFVLGPVSLQVDAGERIGITGPNGAGKSTLLRLLLGRQEPDEGRASL GASVAIGEIDQARALFTGTARLVDRFEEFLPTWTTADVRTLLAKFGLRADHVEREVGRLSPGERTRAGLA LLQARGTNVLVLDEPTNHLDLPAIEQLEQALETYDGALLLVTHDRRMLQNVRLDRRWLVDGGRVTAV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6748 | - | - | 100% (558) | ABC transporter ATPase |
| M. smegmatis MC2 155 | MSMEG_5102 | - | 7e-61 | 33.33% (564) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3140 | - | 2e-57 | 32.09% (536) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1508 | - | 3e-56 | 32.63% (521) | macrolide ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_0995 | - | 0.0 | 85.53% (553) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1473 | - | 3e-56 | 32.63% (521) | macrolide ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01816 | - | 4e-56 | 32.63% (524) | ABC transporter ATP-binding protein, possibly in EF-3 subfamily |
| M. abscessus ATCC 19977 | MAB_4781c | - | 0.0 | 84.45% (553) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2279 | - | 7e-58 | 33.21% (524) | ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3306 | - | 7e-58 | 32.32% (526) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_3711 | - | 1e-59 | 34.61% (549) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_1481 | - | 1e-57 | 33.02% (524) | ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_5841 | - | 0.0 | 86.44% (553) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2279|M.marinum_M -----MITATDLEVRAGARILLSPDGPDLRVQPGDRIGLVGRNGAGKTTT
MUL_1481|M.ulcerans_Agy99 -----MITATDVEVRAGARILLSPDGPDLRVQPGDRIGLVGRNGAGKTTT
MAV_3306|M.avium_104 -----MITATDLEVRAGARILLSPDGPDLRVQPGDRIGLVGRNGAGKTTT
Mb1508|M.bovis_AF2122/97 -----MITATDLEVRAGARILLAPDGPDLRVQPGDRIGLVGRNGAGKTTT
Rv1473|M.tuberculosis_H37Rv -----MITATDLEVRAGARILLAPDGPDLRVQPGDRIGLVGRNGAGKTTT
MLBr_01816|M.leprae_Br4923 -----MITATDLEVRAGARILLSSDGPDLRVQPGDRIGLVGRNGAGKTTT
Mflv_0995|M.gilvum_PYR-GCK ---MTATLVAKNVAGGFAH-RTLFDGVDLTVAPGDVLGVVGVNGAGKSTL
Mvan_5841|M.vanbaalenii_PYR-1 ---MTATLVAKNVAGGFAH-RTLFEGVDLTVAPGDVVGVVGANGAGKSTL
MSMEG_6748|M.smegmatis_MC2_155 MGTMTATLVAKNVAGGFAH-RTLFEGLDLTVARGDVIGVVGANGAGKSTL
MAB_4781c|M.abscessus_ATCC_199 ---MTATLVAKNLAGGFAH-RTLFEGLDVTVAPGDVVGVVGANGAGKSTL
TH_3711|M.thermoresistible__bu -----MSIVFSDVSFAWPDGTALFTDLSFTIGPG-RTGLVAPNGAGKSTL
. . . . . .. : * *:*. *****:*
MMAR_2279|M.marinum_M LRILAGESEPYAGSVTRA---GEIGYLPQDPKEGDLEVLARDRVLSARGL
MUL_1481|M.ulcerans_Agy99 LRILAGESEPYAGSVTRA---GEIGYLPQDPKEGDLEVLARDRVLSARGL
MAV_3306|M.avium_104 LRILAGETEPYAGTIARS---GEIGYLPQDPKEGDLDVLARDRVLSARGL
Mb1508|M.bovis_AF2122/97 LRILAGEVEPYAGSVTRA---GEIGYLPQDPKVGDLDVLARDRVLSARGL
Rv1473|M.tuberculosis_H37Rv LRILAGEVEPYAGSVTRA---GEIGYLPQDPKVGDLDVLARDRVLSARGL
MLBr_01816|M.leprae_Br4923 LRILAGATEPYAGSVTWT---GEIGYLPQDPKVGNLDVLARDRVLSARGL
Mflv_0995|M.gilvum_PYR-GCK LRILARDLEPLEGTVSVAPADAFVGWLPQEHERVPGETVAAYIARRTGCA
Mvan_5841|M.vanbaalenii_PYR-1 LRILAGELEPLDGSVAVAPADAFVGWLPQEHERVPGETVAAYVARRTGCA
MSMEG_6748|M.smegmatis_MC2_155 LRILAGDLDPLEGAVSVAPADAFVGWLPQEHERVPGETVAAYVARRAGCA
MAB_4781c|M.abscessus_ATCC_199 LRILAGDLQPLSGTVGVAPGDAFIGWLPQEHERIPGETVAAYIARRTGCI
TH_3711|M.thermoresistible__bu LDLIAGARRPTSGSVTVD---GTVGHLPQHLPFMPEATVGDVLGITPVLT
* ::* * *:: . :* ***. .:. .
MMAR_2279|M.marinum_M DVLLTDLEKQQALMAEVADDAARDRAIRRYGQLEERFVALGGYGAESEAS
MUL_1481|M.ulcerans_Agy99 DVLLTDLEKQQALMAEVADDAARDRAIRRYGQLEERFVTLGGYGAESEAS
MAV_3306|M.avium_104 DVLLTDLEKQQALMAEVADDDARDRAIRRYGQLEERFVALGGYGAESEAS
Mb1508|M.bovis_AF2122/97 DVLLTDLEKQQALMAEVADEDERDRAIRRYGQLEERFVALGGYGAESEAG
Rv1473|M.tuberculosis_H37Rv DVLLTDLEKQQALMAEVADEDERDRAIRRYGQLEERFVALGGYGAESEAG
MLBr_01816|M.leprae_Br4923 DVLLTDLEKQQALMAEVADDDARDRAIRRYGQLEERFLALGGYSAESEAG
Mflv_0995|M.gilvum_PYR-GCK AATLRMDAAAEELADSEQGAD-------AYSAALEHWLATGAADLDERMP
Mvan_5841|M.vanbaalenii_PYR-1 EATRAMDAAAATLDDAGNGAD-------AYSAALDHWLATGAADLDERLP
MSMEG_6748|M.smegmatis_MC2_155 DATSAMEAAAAALADPTSNADPAVDPAEAYSAALDHWLATGAADLDERLP
MAB_4781c|M.abscessus_ATCC_199 AATEAMESAAAALADQVQGRAD---LADEYSVAFDRWLACGAADLEDRVP
TH_3711|M.thermoresistible__bu ALDALAAGDASEAVFAAIGDD---------------------WDVEERCR
. . :..
MMAR_2279|M.marinum_M RICASLGLPERVLTQQ---LRTLSGGQRRRVELARILFAASD---TGAGS
MUL_1481|M.ulcerans_Agy99 RICASLGLPERVLTQQ---LRTLSGGQRRRVELARILFAASD---TGAGS
MAV_3306|M.avium_104 RICASLGLPERVLTQQ---LRTLSGGQRRRVELARILFAAAEGGATGSGS
Mb1508|M.bovis_AF2122/97 RICASLGLPERVLTQR---LRTLSGGQRRRVELARILFAASE---SGAGN
Rv1473|M.tuberculosis_H37Rv RICASLGLPERVLTQR---LRTLSGGQRRRVELARILFAASE---SGAGN
MLBr_01816|M.leprae_Br4923 RICASLGLPERVLVQQ---LCTLSGGQRRRVELARILFAASRAGTGASGS
Mflv_0995|M.gilvum_PYR-GCK AVLADLGLDSDAVRPESTMMTALSGGQAARVGLAALMLSRFD--------
Mvan_5841|M.vanbaalenii_PYR-1 AVLADLGLDSDAVRPDSTPMTALSGGQAARVGLAALLLSRFD--------
MSMEG_6748|M.smegmatis_MC2_155 AVLADLGLDTEMVRPDSTLMTALSGGQAARVGLAALLVSRFD--------
MAB_4781c|M.abscessus_ATCC_199 AVLNDVGLGPDTVRPASTLMTSLSGGQAARVGLAALVLSRFD--------
TH_3711|M.thermoresistible__bu GMLDRLGLGEVAVDRR---LGSLSGGEVVAVGLAAQLLRRPE--------
: :** : : :****: * ** :.
MMAR_2279|M.marinum_M STVLLLDEPTNHLDADSVGWLRDFLRAHTGGLIIISHNVELLADVVNRVW
MUL_1481|M.ulcerans_Agy99 STVLLLDEPTNHLDADSVGWLRDFLRAHTGGLIIISHNVELLADVVNRVW
MAV_3306|M.avium_104 ATTLLLDEPTNHLDADSIGWLRDFLRAHTGGLVIISHNVELLADVVNRVW
Mb1508|M.bovis_AF2122/97 STTLLLDEPTNHLDADSLGWLRDFLRLHTGGLVVISHNVDLVADVVNKVW
Rv1473|M.tuberculosis_H37Rv STTLLLDEPTNHLDADSLGWLRDFLRLHTGGLVVISHNVDLVADVVNKVW
MLBr_01816|M.leprae_Br4923 GTTLLLDEPTNHLDADSLGWLRDFLRSHTGGLVVISHNVELIAAVVNRVW
Mflv_0995|M.gilvum_PYR-GCK --IVLLDEPTNDLDLDGLDRLERLVRELRGGVVLVSHDREFLARSVTRVL
Mvan_5841|M.vanbaalenii_PYR-1 --IVLLDEPTNDLDLDGLARLERFVSELRGGVVLVSHDREFLARTVTRVL
MSMEG_6748|M.smegmatis_MC2_155 --IVLLDEPTNDLDLDGLDRLEAFVRDLRGGVVLVSHDREFLARSVTGVL
MAB_4781c|M.abscessus_ATCC_199 --VVLLDEPTNDLDLDGLARLEDFVRDLRGGVVLVSHDREFLARSVTHVL
TH_3711|M.thermoresistible__bu --VLLLDEPTNNLDADARRRLHAALDDYPGTLLVVSHDRVLLDRMER---
:*******.** *. *. : * ::::**: ::
MMAR_2279|M.marinum_M FLDAVRGEVDVYNMGWHKYLDARATDEQRRRR-------ERANAERKATA
MUL_1481|M.ulcerans_Agy99 FLDAVRGEVDVYNMGWHKYLDARATDEQRRRR-------ERANAERKATA
MAV_3306|M.avium_104 FLDAVRGEVDVYNMSWQKYLDARATDEQRRRR-------ERANAERKAAA
Mb1508|M.bovis_AF2122/97 FLDAVRGQVDVYNMGWQRYVDARATDEQRRIR-------ERANAERKAAA
Rv1473|M.tuberculosis_H37Rv FLDAVRGQVDVYNMGWQRYVDARATDEQRRIR-------ERANAERKAAA
MLBr_01816|M.leprae_Br4923 FLDAVLGKVDVYNMGWYKYLDSRATDEQRRRR-------ERVNAERKATA
Mflv_0995|M.gilvum_PYR-GCK ELDLAQHTTTVFGGGYESYLEEREVNRRHRREQYEEFADRKADLVARARV
Mvan_5841|M.vanbaalenii_PYR-1 ELDLAQNTTTVFGGGYESYLEERAVNRRHRREQYEEFADKKADLVARARV
MSMEG_6748|M.smegmatis_MC2_155 ELDLAQNTNTLYGGGYDSYLEEREVNRRHKREQYDEFAEKKADLVARARV
MAB_4781c|M.abscessus_ATCC_199 ELDLAQNRTTVFGGGYESYLEERAVARRHRREQYEEFAEKKADLVARARI
TH_3711|M.thermoresistible__bu IAELYRGEMLFYGGNFTTYQRQLAADQQSARNDVRHAEQSLRREKRERQQ
: .:. .: * . .: . .
MMAR_2279|M.marinum_M LRTQAAKMGAKATKAVAAQN--------MLRRADRMMAALDEERVADKVA
MUL_1481|M.ulcerans_Agy99 LRTQAAKMGAKATKAVAAQN--------MLRRADRMMAALDEERVADKVA
MAV_3306|M.avium_104 LRTQAAKLGAKATKAVAAQN--------MLRRADRMMAALDEERVADKVA
Mb1508|M.bovis_AF2122/97 LRAQAAKLGAKATKAVAAQN--------MLRRADRMMAALDEERVADKVA
Rv1473|M.tuberculosis_H37Rv LRAQAAKLGAKATKAVAAQN--------MLRRADRMMAALDEERVADKVA
MLBr_01816|M.leprae_Br4923 LRTQAAKMGAKATKAVAAQN--------MLRRADRMMAALDEERVIEKVA
Mflv_0995|M.gilvum_PYR-GCK QREWSSQGVRNAIRKAPDN-------DKIRRRAASESSEKQAQKVRQMES
Mvan_5841|M.vanbaalenii_PYR-1 QREWSSQGTRNAIRKAPDN-------DKIRRRAATESSEKQAQKVRQMES
MSMEG_6748|M.smegmatis_MC2_155 QREWSSQGVRNAIRKAPDN-------DKIRRRAATESSEKQAQKVRQMES
MAB_4781c|M.abscessus_ATCC_199 QREWSSQGVRNAIRKAPDN-------DKIRRRAASESSEKQAQKVRQMES
TH_3711|M.thermoresistible__bu ARERAARRSGTAARTVKDAGLPRIVAGAMKRRAQESAGRTDEVRAARIAA
* ::: .* : . : *** . : :. :
MMAR_2279|M.marinum_M RIKFPTPAACGRVP-------------------LVVKGLSKTYGSLEVFT
MUL_1481|M.ulcerans_Agy99 RIKFPTPAACGRVP-------------------LVVKGLSKTYGSLEVFT
MAV_3306|M.avium_104 RIKFPTPAACGRTP-------------------LTATGLSKSYGSLEVFS
Mb1508|M.bovis_AF2122/97 RIKFPTPAACGRTP-------------------LVANGLGKTYGSLEVFT
Rv1473|M.tuberculosis_H37Rv RIKFPTPAACGRTP-------------------LVANGLGKTYGSLEVFT
MLBr_01816|M.leprae_Br4923 QIKFPTPAACGRTP-------------------LVAKGLSKTYGSLEVFT
Mflv_0995|M.gilvum_PYR-GCK RIARLEEVEEPRKE---WQLQFTIGSAPRSSSVVATLDKAVVRLPDFVLG
Mvan_5841|M.vanbaalenii_PYR-1 RIARLEEVEEPRKE---WTLQFTIGEAPRSSAVVATLDNAVVRQGDFVLG
MSMEG_6748|M.smegmatis_MC2_155 RIARLEEVEEPRKE---WVLQFSIGAAPRSSTVVATLDNAVVRQGNFVLG
MAB_4781c|M.abscessus_ATCC_199 RIARLEEVVEPRKE---WVLEFTIGAAPRSSAVVATLENAVVRQGEFVLG
TH_3711|M.thermoresistible__bu GRARLEEAEKRLRDDDAMVLDLPDTTVPAGRTVFAGSGLTVGN----VLR
. .. *:
MMAR_2279|M.marinum_M GVDLAIDRGSRVVVLGLNGAGKTTLLRLLAGVEHPDTGGLEPGHGLRIGY
MUL_1481|M.ulcerans_Agy99 GVDLAIDRGSRVVVLGLNGAGKTTLLRLLAGVEHPDTGGLEPGHGLRIGY
MAV_3306|M.avium_104 GVDLAIDRGSRVVVLGLNGAGKTTLLRLLAGAETPDTGRIEPGHGLRIGY
Mb1508|M.bovis_AF2122/97 GVDLAIDRGSRVVILGLNGAGKTTLLRLLAGVEQPDTGVLEPGYGLRIGY
Rv1473|M.tuberculosis_H37Rv GVDLAIDRGSRVVILGLNGAGKTTLLRLLAGVEQPDTGVLEPGYGLRIGY
MLBr_01816|M.leprae_Br4923 GVNLAIDRGSRVVVLGLNGAGKTTLLRVLAGAEKPDVGRLEPGHGLRIGY
Mflv_0995|M.gilvum_PYR-GCK PVSLQVDAGERIGITGPNGAGKSTLLRLLLGRCQPDDGRASLGANVAIGE
Mvan_5841|M.vanbaalenii_PYR-1 PVALQVDAGERIGITGPNGAGKSTLLRLLLGRLLPDEGRASMGASVEIGE
MSMEG_6748|M.smegmatis_MC2_155 PVSLQVDAGERIGITGPNGAGKSTLLRLLLGRQEPDEGRASLGASVAIGE
MAB_4781c|M.abscessus_ATCC_199 PVSLQVDAGERIGITGPNGAGKSTLLRLLLGRQQPDEGRASLGANVAIGE
TH_3711|M.thermoresistible__bu GIDLTVRGPERIALTGANGVGKTTLLRVIGGRLAPDAGTVTR-ADGRIAY
: * : .*: : * **.**:****:: * ** * . *.
MMAR_2279|M.marinum_M FAQEHDTLDNDATVWENIRHAAPESGEQELRGLLGAFMFTGPQLDQPAGT
MUL_1481|M.ulcerans_Agy99 FAQEHDTLDNDATVWENIRHAAPESGEQELRGLLGAFMFTGPQLDQPAGT
MAV_3306|M.avium_104 FAQEHDTLDNDATVWQNIRHAAPDSGEQDLRGLLGAFMFSGPQLDQPAGT
Mb1508|M.bovis_AF2122/97 FAQEHDTLDNDATVWENVRHAAPDAGEQDLRGLLGAFMFTGPQLEQPAGT
Rv1473|M.tuberculosis_H37Rv FAQEHDTLDNDATVWENVRHAAPDAGEQDLRGLLGAFMFTGPQLEQPAGT
MLBr_01816|M.leprae_Br4923 FAQEHDTLDNEDTVWQNIRHTAPEFGEQDLRGLLGAFMFSGPQLDQLAGT
Mflv_0995|M.gilvum_PYR-GCK IDQARAEFTGADRLVDRFEQRVPDWTTADVRTLLAKFGLTADHVERGIDE
Mvan_5841|M.vanbaalenii_PYR-1 IDQARAYFTGPERLLDRFEQRVPEWPTADVRTLLAKFGLGADHVERAVDE
MSMEG_6748|M.smegmatis_MC2_155 IDQARALFTGTARLVDRFEEFLPTWTTADVRTLLAKFGLRADHVEREVGR
MAB_4781c|M.abscessus_ATCC_199 IDQARADFTGTDRLVDRFEQRVPAWSTADARTLLAKFGLRADHVERTVDE
TH_3711|M.thermoresistible__bu LSQRLDLLDPGQTVLDNLAEFAPTLSVTGRRHLLARFLFDDKRIALPIRA
: * : : :.. . * * **. * : ::
MMAR_2279|M.marinum_M LSGGEKTRLALAGLVAST--ANVLLLDEPTNNLDPASREQVLDALRSYQG
MUL_1481|M.ulcerans_Agy99 LSGGEKTRLALAGLVAST--ANVLLLDEPTNNLDPASREQVLDALRSYQG
MAV_3306|M.avium_104 LSGGEKTRLALAGLVAST--ANVLLLDEPTNNLDPASREQVLDALRSYTG
Mb1508|M.bovis_AF2122/97 LSGGEKTRLALAGLVAST--ANVLLLDEPTNNLDPASREQVLDALRSYRG
Rv1473|M.tuberculosis_H37Rv LSGGEKTRLALAGLVAST--ANVLLLDEPTNNLDPASREQVLDALRSYRG
MLBr_01816|M.leprae_Br4923 LSGGEKTRLALAGLVAST--ANVLLLDEPTNNLDPASRKQVLDALRNYQG
Mflv_0995|M.gilvum_PYR-GCK LSPGERTRAGLALLQARG--TNVLVLDEPTNHLDLPAIEQLEAALDTYDG
Mvan_5841|M.vanbaalenii_PYR-1 LSPGERTRAGLALLQACG--TNVLVLDEPTNHLDLPAIEQLEQALESYDG
MSMEG_6748|M.smegmatis_MC2_155 LSPGERTRAGLALLQARG--TNVLVLDEPTNHLDLPAIEQLEQALETYDG
MAB_4781c|M.abscessus_ATCC_199 LSPGERTRAGLALLQACG--TNVLVLDEPTNHLDLAAIEQLEQALETYDG
TH_3711|M.thermoresistible__bu LSGGERLRATLACVLHAEPAPQLLLLDEPTNNLDLTSIAQLESALIAYRG
** **: * ** : .::*:******:** .: *: ** * *
MMAR_2279|M.marinum_M AVVLVTHDPGAAEALDPQRVVLLPDATEDYWSDEYRDLIELA
MUL_1481|M.ulcerans_Agy99 AVVLVTHDPGAAEALDPQRVVLLPDATEDYWSDEYRDLIELA
MAV_3306|M.avium_104 AVVLVTHDPGAAEALDPQRVVLLPDGTEDYWSDEYRDLIELA
Mb1508|M.bovis_AF2122/97 AVVLVTHDPGAAAALGPQRVVLLPDGTEDYWSDEYRDLIELA
Rv1473|M.tuberculosis_H37Rv AVVLVTHDPGAAAALGPQRVVLLPDGTEDYWSDEYRDLIELA
MLBr_01816|M.leprae_Br4923 AVVLVTHDPGAAKALDPQRVVLLPDGTEDYWSDEYRDLIELA
Mflv_0995|M.gilvum_PYR-GCK ALLLVTHDRRMLQNVRLDRYWRVDGGQVSETQR---------
Mvan_5841|M.vanbaalenii_PYR-1 ALLLVTHDRRMLQNVRLDRSWRVENGQVTEL-----------
MSMEG_6748|M.smegmatis_MC2_155 ALLLVTHDRRMLQNVRLDRRWLVDGGRVTAV-----------
MAB_4781c|M.abscessus_ATCC_199 ALLLVTHDRRMLQNVRLDRAWAVDNGCVTER-----------
TH_3711|M.thermoresistible__bu AFIVVSHDDRFVAAIGVNRRLRLSDGKLS-------------
*.::*:** : :* : ..